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Cutting-Edge PK and Immunogenicity Strategies for Next-Generation ADCs, ARCs, and Conjugated Biotherapeutics, Upcoming Webinar Hosted by Xtalks

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In this free webinar, learn about the latest bioanalytical techniques for antibody-drug conjugates (ADCs), antibody-RNA-conjugates (ARCs) and antibody-peptide conjugates, including ligand-binding assays, LC-MS/MS and multiplexing approaches. The featured speakers will share insights into essential PK methods, platform selection strategies and immunogenicity challenges in bioanalysis, supported by real-world case studies. The speakers will also discuss the regulatory requirements for the bioanalysis of conjugated drugs, key reagent selection and strategies to ensure compliance in drug development.

TORONTO, March 28, 2025 /PRNewswire-PRWeb/ — In this webinar, the expert speakers will explore advanced conjugation technologies such as antibody-drug conjugates (ADCs), antibody-RNA-conjugates (ARCs), siRNA/oligos and antibody-peptide conjugates, as well as discuss the best bioanalytical support strategies for these therapies.

Having a therapeutic entity with multiple distinct components means that we need to have analytical methodologies for various components.

Bioanalysis for support of next-generation ADCs and ARCs have exploded recently due to the efficacy and safety that these therapies offer for immuno-oncology, rare diseases, vaccines and potentially many other diseases.

ADCs tend to consist of a toxic small molecule payload attached via a linker to an antibody. The application of these drugs had mainly been in oncology where their mode of action is for the antibody to attach at the desired target site with subsequent release of the small molecule to combat tumor cells. Recently, we have seen a much wider application or use of “ADCs” to other modalities such as antibody-peptide conjugates, ARCs or even other more complicated multi-functional entities.

Having a therapeutic entity with multiple distinct components means that we need to have analytical methodologies for various components. Traditionally, LC-MS/MS has mainly been applied to the quantitation of the small molecule payload or the linker moiety. Ligand-binding assays had been successful for quantitation of the intact ADC or the antibody portion.

The expert speakers will discuss the latest and greatest conjugation technologies (ADCs, ARCs/siRNA/Oligo’s, antibody-peptide conjugates) and how best to support them bioanalytically. Those attending will specifically have the benefit of learning which PK methods are required for bioanalysis of conjugated drugs, various platforms used for PK methods, strategies for selection of the platform to be used for PK methods and PK case studies of conjugated drugs.

Additionally, this webinar will discuss immunogenicity strategies and case studies for support of conjugated drugs. Attendees will also learn what critical reagents are needed/recommended for support of conjugated drugs, challenges with multiplexing PK assays and regulatory expectations. Register for this webinar to learn how best to address these challenges.

Join experts from KCAS Bio, Dominic Warrino, PhD, Senior Director of Scientific Services; and Dawn Dufield, PhD, Scientific Officer, Mass Spectrometry, for the live webinar on Thursday, April 17, 2025, at 11am EDT (4pm BST/UK).

For more information, or to register for this event, visit Cutting-Edge PK and Immunogenicity Strategies for Next-Generation ADCs, ARCs, and Conjugated Biotherapeutics.

ABOUT XTALKS

Xtalks, powered by Honeycomb Worldwide Inc., is a leading provider of educational webinars and digital content to the global life science, food, healthcare and medical device communities. Every year, thousands of industry practitioners (from pharmaceutical, biotechnology, food, healthcare and medical device companies, private & academic research institutions, healthcare centers, etc.) turn to Xtalks for access to quality content. Xtalks helps professionals stay current with industry developments, regulations and jobs. Xtalks webinars also provide perspectives on key issues from top industry thought leaders and service providers.

To learn more about Xtalks visit https://xtalks.com
For information about hosting a webinar visit https://xtalks.com/why-host-a-webinar/

Contact:
Vera Kovacevic
Tel: +1 (416) 977-6555 x371
Email: vkovacevic@xtalks.com

Media Contact

Vera Kovacevic, Xtalks, +1 (416) 977-6555 x371, vkovacevic@xtalks.com, www.xtalks.com

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WAVLINK Giant Stream6 AI-Powered WiFi 6 Router Receives Strong Support Within 48 Hours on Kickstarter

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Combining AI-enhanced connectivity with Advanced Security, the Giant Stream6 Brings the Future of WiFi to Every Home

NEW YORK, April 4, 2025 /PRNewswire/ — Just two days after launching on Kickstarter, the WAVLINK Giant Stream6 AI-Enhanced AX6000 Router has captured the attention of tech enthusiasts and families alike, quickly surpassing initial funding goals. The Giant Stream6 is designed for a new generation of high-speed, AI-optimized internet that adapts seamlessly to the connectivity needs of every household, delivering performance and security with effortless precision. By combining cutting-edge WiFi 6 technology, intelligent traffic management, and robust security features, the Giant Stream6 is changing how users experience home connectivity.

“We are beyond thrilled by the support and enthusiasm we’ve received,” shares John, WAVLINK’s CEO. “It’s clear that today’s users are ready for a smarter, more intuitive router experience, and the Giant Stream6 delivers just that. We designed this router to handle everything from gaming to streaming to remote work—all while providing top-tier security and ease of use for families.”

Standout Features of the Giant Stream6:

AI-Enhanced QoE Modes: Adaptive modes (AI, Gaming, Streaming, Meeting, and Work From Home) automatically prioritize bandwidth to fit the moment, ensuring each device gets the performance it needs, precisely when it needs it.WiFi 6 Speeds and Coverage: With dual-band speeds reaching up to 6000 Mbps and eight omnidirectional antennas, the Giant Stream6 blankets large homes with fast, reliable connectivity.Advanced Security Suite: Built-in AD GuardHome, Secure DNS, VPN Privacy Protection, and a dedicated Guest WiFi network offer peace of mind, safeguarding the family’s digital experience.Mesh Compatibility: Paired with WAVLINK Everything Mesh, the Giant Stream6 eliminates dead zones, providing seamless coverage across every room.Parental Controls & Easy Management: Users can set screen time limits, content filters, and device prioritization from an intuitive interface, making network management simple and accessible.

Elevating Home Connectivity with Intelligent, User-Friendly Design

The Giant Stream6 is more than just a high-performance router; it’s a digital companion designed to evolve with users’ needs. Its AI-driven QoE modes adapt automatically, managing traffic without the need for constant adjustments. From uninterrupted gaming sessions to smooth video calls and secure browsing, the Giant Stream6 is redefining what a home network can achieve.

WAVLINK: Redefining Connectivity for Modern Living

WAVLINK continues to innovate with the mission to enhance daily life through better connectivity. The Giant Stream6 is the latest addition to a lineup of products aimed at making tech simple, efficient, and powerful—empowering users to do more in a connected world.

To join the campaign and back the Giant Stream6 on Kickstarter, visit here.

More WAVLINK products, click here.

Contact: 
zhouying@wavlink.com

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BlackDoctor.org Announces Inductees in First Hall of Fame, BDOs Highest Distinction, Recognizing Lifetime Achievements in the US Healthcare Industry

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CHICAGO, April 4, 2025 /PRNewswire/ — In a historic moment, BlackDoctor.org (BDO) inducts its first class into the inaugural TBH Hall of Fame, BDOs highest distinction. This milestone, to be announced during the 10th anniversary of the Top Blacks in Healthcare Awards Ceremony, honors those who have made groundbreaking contributions and impacted the lives of generations to come.

A Key Partner to Healthcare Stakeholders, BDO Prepares Unforgettable Experience at Fontainebleau Miami April 9-10, 2025.

The inductees, selected through a rigorous and thoughtful process, have demonstrated unwavering dedication to improving and saving lives. Their innovations, leadership, and advocacy have transformed the lives of millions of Black Americans.

“It is our honor and pleasure to recognize 11 exceptional individuals who are industry leaders in healthcare. Their long-lasting impact should never be forgotten,” said Reggie Ware, CEO, BlackDoctor.org. “The TBH Hall of Fame is a first for BDO, and we felt it was the perfect time given it’s our 10th anniversary for Top Blacks in Healthcare and our 20th anniversary for BlackDoctor.org.” 

Added Executive Editor Jade Curtis, “The TBH Hall of Fame inductees leave a legacy that will continue to inspire future generations, and we remain committed to sharing their stories because we know that where there is no vision, the people perish.”

Introducing: The Inaugural class of 2025 TBH Hall of Fame Inductees

The Hall of Fame honors 11 medical giants to cement their rich legacy in their rightful place in history. In addition to the Hall of Fame, BDO recognizes this year’s 12 distinguished TBH honorees for innovative thinking, contributions and leadership that inspire greatness in our industry – for now and for generations to come.

Vanessa Broadhurst, EVP, Global Corporate Affairs, Johnson & Johnson, Zoetis Board Member
Craig Emmitt Cole, MD, Hematologist, Karmanos Cancer Institute    
Tony Ezell, Executive Vice President, President of the Americas, BD (Becton, Dickinson and Company)
Reshema Kemps-Polanco, Executive Vice President and Chief Commercial Officer, Novartis
Michael LeNoir, MD, F.A.A.P, F.A.A.A.A Pediatrician, allergist
Freda Lewis-Hall, MD, Life Sciences Leader
Ted Love, MD, Chair, BIO Board of Directors
Myrtle Potter, Chair and CEO, Director, Former Chair & CEO, Sumitomo Pharma America
Reed Tuckson, MD, FACP, Managing Director of Tuckson Health Connections
Mitzi Joi Williams, MD, Founding Medical Director at Joi Life Wellness Group Neurology Center in Atlanta, GA
Richard Allen Williams, MD, Founder and President of the Minority Health Institute and Association of Black Cardiologists (ABC)

Hall of Fame inductees offer advice for aspiring leaders:

“Innovate with empathy.  When empathy is combined with transformational science and excellent business acumen, the remarkable is possible,” said Reshema Kemps-Polanco, Executive Vice President and Chief Commercial Officer, Novartis. “Seek to understand the lived experiences of those you aim to serve- patients, caregivers, healthcare systems, and those who invest in your endeavors.”

“Be prepared to work hard,” advised Ted Love, MD, Chair, BIO Board of Directors. “The path to success in this field is competitive. However, if you genuinely love the work, you’ve already won half the battle.”

“Keep your mentors but secure sponsors, who are senior individuals who take actions on your behalf,” advised Myrtle Potter, Chair and CEO, Director, Former Chair & CEO Sumitomo Pharma America

“Be authentic. Apply your unique insights, perspectives and experiences to your work. You will then bring truly novel solutions,” said Freda Lewis-Hall, MD, Life Sciences Leader.

“My best advice for future generations of Black doctors is not to let anyone define you and tell you what you can or cannot do,” said Richard Allen Williams, MD, Founder and President of the Minority Health Institute and Association of Black Cardiologists (ABC).

About BlackDoctor.org (BDO)  

BlackDoctor.org is the leading health and wellness destination for people of color, leveraging culture, content and technology to transform people’s lives for the better.

Celebrating its 20th year, BDO has a monthly audience reach of 26 million on social media and 6.5 million monthly visitors to its website. BlackDoctor.org boasts the largest online database of Black physicians and dentists as part of its free doctor search tool.  BDO has leveraged AI to create the “BlackDoctor Chat bot” which is the first AI tool providing culturally relevant answers to Black consumers’ most pressing health questions.  Consumers can ask it anything they want!

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Axon Global CEO Israel Martinez Named Security Expert of the Year at HMG Strategy Summit in Dallas

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Israel Martinez, CEO and Global CTO of Axon Global, was named Security Expert of the Year at the HMG Strategy Summit in Dallas, the largest network of CIOs and CISOs in the U.S. with over 300,000 technology executives globally. Martinez was honored for his groundbreaking work in AI-driven cybersecurity and a 20-year track record of zero reportable breaches across high-risk, high-impact environments. He also spoke on a featured panel addressing the escalating threat of geopolitical cyberattacks and the critical need for global cyber resilience.

DALLAS, April 4, 2025 /PRNewswire-PRWeb/ — Israel Martinez, CEO and Global CTO of Axon Global, was honored with the HMG Global Leadership Institute Award for Security Expert of the Year at the HMG Strategy Executive Leadership Summit in Dallas. The event brought together top technology executives from across the country for a day of thought leadership, innovation, and strategic insights.

“Israel is fearlessly committed to innovation and integrity—and when lives are on the line, his team shows up.” — August Pelliccio, Executive Editor, Digital, HMG Strategy,

Martinez also took the stage as a featured speaker during the Executive Panel: Securing the Future Against Geopolitical Cyber Risks, joining Mignona Cote (CISO, Infor Global Solutions) and Art Harvey (CISO, Dovenmuehle) for a dynamic conversation on the rising threat of state-sponsored cyberattacks and the critical importance of international collaboration, proactive threat intelligence, and executive-led cyber resilience.

During the award presentation, HMG Strategy highlighted Martinez’s exceptional track record:

“Israel has helped protect everything from billion-dollar enterprises to space programs, with a track record of zero reportable breaches—by the way—across twenty years and countless high-risk clients.

Right now he’s pioneering an AI agent-driven model, building out a team of two hundred LLM-powered experts that already compete and win against the best in the world.

How’s this for a case study? One of the teams he worked with monetized IT for the Olympics, turning it into a profit engine rather than just a cost center. They increased media revenue by 300% and eliminated redundant global oversight.

Israel is fearlessly committed to innovation and integrity, and when lives are on the line, his team shows up. As one Commander put it, ‘Thank you for pulling so many technology resources together to rescue my daughter.’

There are only so many clips I can share in the brief time we have on stage, but I hope what I’ve shared expresses some of the gravity of the work Israel has done—and how deserving he is of this honor.”

HMG Strategy is recognized as the largest network of CIOs and CISOs in the United States, with over 300,000 IT executives globally. Its Executive Leadership Summits are known for convening top-tier professionals to tackle the most urgent challenges in technology and business.

Media Contact

Kaitlyn Procter, Axon Global, 1 2027055053, kaitlynpr@axoncyber.com, https://axoncyber.com

View original content to download multimedia:https://www.prweb.com/releases/axon-global-ceo-israel-martinez-named-security-expert-of-the-year-at-hmg-strategy-summit-in-dallas-302421119.html

SOURCE Axon Global

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