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Biopharma exec says Bitcoin could help industry through ‘biotech winter’

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NASDAQ-listed biopharmaceutical firm Atai Life Sciences says cryptocurrencies like Bitcoin could be key to survival for biotech startups as they wade through years of regulatory approvals. 

Atai, which is developing mental health treatments using psychedelics like DMT and MDMA, has become the latest public company to announce plans to buy Bitcoin.

It plans to buy $5 million of Bitcoin (BTC), its founder and chair Christian Angermayer wrote in a March 20 Substack post.

“Drug development is a cash-hungry, long-term venture,” he said. “The necessary steps to achieve regulatory approval can easily take more than a decade.”

TechCrunch reported in January that, according to multiple data sets, the number of startups shutting down rose in 2024 compared to 2023 as firms failed to receive more funding to keep running.

Angermayer said the approval process is essential for drug development, but it exposes firms to financial risks while sticky inflation and high interest rates have caused the current “biotech winter.”

Source: Christian Angermayer

He added that the current industry approach is to put cash reserves in near-zero-yield accounts, as “preserving capital was more important than earning a return on their cash balance.”

“This context sets the stage for considering unconventional treasury moves — like adding Bitcoin to the treasury — to address the twin threats of inflation and low-yielding reserves, and in general to optimize and maximize shareholder value.”

Atai will join at least five other public medical companies that have bought Bitcoin in recent months with the aim of boosting shareholder returns.

Biotech firm Quantum BioPharma said on March 20 that it had now spent $3.5 million in total to buy BTC and other cryptocurrencies after an initial $1 million investment in December. 

Medical device maker Semler Scientific said last month that since it started in May, it had spent a total of $280.4 million buying 3,192 BTC.

Hoth Therapeutics, Acurx Pharmaceuticals and Enlivex Therapeutics said in separate statements on Nov. 20 that each of them would buy $1 million in Bitcoin.

Related: Michael Saylor’s Strategy plans to offer 5M shares to buy more Bitcoin

Atai’s Angermayer said his firm’s Bitcoin buy would primarily be as a long-term inflation hedge but also a short-term diversification play. He added that Bitcoin is likely to have short-term price fluctuations, so the Berlin-based firm is holding mostly US dollars, short-term securities, and stocks for its desired run rate into 2027.

Atai’s $5 million put would mean it is able to buy just over 59 BTC at its current price of around $84,300 and make it the world’s 52nd largest holder among public firms, according to Bitbo data.

Bitcoin has struggled to keep afloat amid a wider market rout due to US President Donald Trump’s tariff threats and fears of a US recession, which Trump hasn’t ruled out.

Atai’s share price rose early in March 20 trading to a peak of $1.47 but tapered off to close the day down 1.44% at $1.37, according to Google Finance. Its stock has sunk nearly 93% from its mid-2021 public debut peak but is up 3% so far this year.

Magazine: Crypto fans are obsessed with longevity and biohacking — Here’s why

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Bitget CEO slams Hyperliquid’s handling of “suspicious” incident involving JELLY token

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Gracy Chen, CEO of cryptocurrency exchange Bitget, criticized Hyperliquid’s handling of a March 26 incident on its perpetual exchange, saying it put the network at risk of becoming “FTX 2.0.”

On March 26, Hyperliquid, a blockchain network specializing in trading, said it delisted perpetual futures contracts for the JELLY token and would reimburse users after identifying “evidence of suspicious market activity” tied to the instruments. 

The decision, which was reached by consensus among Hyperliquid’s relatively small number of validators, flagged existing concerns about the popular network’s perceived centralization.

“Despite presenting itself as an innovative decentralized exchange with a bold vision, Hyperliquid operates more like an offshore [centralized exchange],” Chen said, after saying “Hyperliquid may be on track to become FTX 2.0.”

FTX was a cryptocurrency exchange run by Sam Bankman-Fried, who was convicted of fraud in the US after FTX’s abrupt collapse in 2022. 

Chen did not accuse Hyperliquid of specific legal infractions, instead emphasizing what she considered to be Hyperliquid’s “immature, unethical, and unprofessional” response to the event.

“The decision to close the $JELLY market and force settlement of positions at a favorable price sets a dangerous precedent,” Chen said. “Trust—not capital—is the foundation of any exchange […] and once lost, it’s almost impossible to recover.”

Source: Gracy Chen

Related: Hyperliquid delists JELLY perps, citing ‘suspicious’ activity

JELLY incident

The JELLY token was launched in January by Venmo co-founder Iqram Magdon-Ismail as part of a Web3 social media project dubbed JellyJelly. 

It initially reached a market capitalization of roughly $250 million before falling to the single digit millions in the ensuing weeks, according to DexScreener. 

On March 26, JELLY’s market cap soared to around $25 million after Binance, the world’s most popular crypto exchange, launched its own perpetual futures tied to the token. 

The same day, a Hyperliquid trader “opened a massive $6M short position on JellyJelly” and then “deliberately self-liquidated by pumping JellyJelly’s price on-chain,” Abhi, founder of Web3 company AP Collective, said in an X post.

BitMEX founder Arthur Hayes said initial reactions to Hyperliquid’s JELLY incident overestimated the network’s potential reputational risks.

“Let’s stop pretending hyperliquid is decentralised. And then stop pretending traders actually [care],” Hayes said in an X post. “Bet you $HYPE is back where [it] started in short order cause degens gonna degen.”

Binance launched JELLY perps on March 26. Source: Binance

Growing pains

On March 12, Hyperliquid grappled with a similar crisis caused by a whale who intentionally liquidated a roughly $200 million long Ether (ETH) position. 

The trade cost depositors into Hyperliquid’s liquidity pool, HLP, roughly $4 million in losses after forcing the pool to unwind the trade at unfavorable prices. Since then, Hyperliquid has increased collateral requirements for open positions to “reduce the systemic impact of large positions with hypothetical market impact upon closing.” 

Hyperliquid operates the most popular leveraged perpetuals trading platform, controlling roughly 70% of market share, according to a January report by asset manager VanEck. 

Perpetual futures, or “perps,” are leveraged futures contracts with no expiry date. Traders deposit margin collateral, such as USDC, to secure open positions.

According to L2Beat, Hyperliquid has two main validator sets, each comprising four validators. By comparison, rival chains such as Solana and Ethereum are supported by approximately 1,000 and 1 million validators, respectively. 

More validators generally lessen the risk of a small group of insiders manipulating a blockchain. 

Magazine: What are native rollups? Full guide to Ethereum’s latest innovation

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GameStop jumps 12% after Bitcoin purchase plans announced

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GameStop shares jumped nearly 12% on March 26 after the company announced plans to purchase Bitcoin (BTC).

The company plans to finance the purchase through debt financing. After markets closed on March 26, GameStop announced a $1.3 billion convertible notes offering.

The convertible senior notes — debt that can later be converted into equity — will be used for general corporate purposes, including acquiring Bitcoin, according to a company statement.

“GameStop expects to use the net proceeds from the offering for general corporate purposes, including the acquisition of Bitcoin in a manner consistent with GameStop’s Investment Policy,” it said.

The company revealed on March 25 plans to use a portion of its corporate cash or future debt to buy digital assets, including Bitcoin and US-dollar-pegged stablecoins. GameStop’s cash reserves stood at $4.77 billion on Feb. 1 compared to $921.7 million one year earlier.

According to Google Finance, GameStop shares closed at $28.36 on the NYSE, marking an 11.65% gain for the day.

GameStop stock performance on March 26. Source: Google Finance

The company reported a net income of $131.3 million for Q4 2024 compared to $63.1 million for the prior year Q4. Although net sales had fallen $511 million year-over-year, the company has been aggressively cutting expenses, including closing 590 stores throughout the United States in 2024.

GameStop was once at the center of the 2021 meme stock craze when retail traders orchestrated a “short squeeze” that sent the price of the stock soaring. Some hedge funds closed down as a result of losses sustained during the short squeeze, giving the GameStop meme stock rise a “David vs. Goliath” narrative.

Related: GameStop buying Bitcoin would ‘bake the noodles’ of TradFi: Swan exec

More companies adopt Bitcoin reserve strategy

GameStop is following the lead of Strategy, which first added Bitcoin to its treasury in August 2020. As of December 2024, Strategy’s stock had gained 3200% since adopting its crypto strategy.

Metaplanet, a Japanese company with plans to buy 21,000 BTC by 2026, saw its stock price rise 4800% since announcing the move. In promotional materials, Metaplanet said it had attracted a significant number of new investors, with its market capitalization rising by 6300%.

Semler Scientific also saw a spike in its share price after announcing plans to purchase Bitcoin.

According to CoinGecko, 32 publicly traded companies hold BTC on their balance sheets.

Magazine: SEC’s U-turn on crypto leaves key questions unanswered

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Yield-bearing stablecoins could kill banking — US Senator Gillibrand

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Stablecoin issuers should be restricted from providing yield-bearing opportunities to protect the legacy banking system, which issues home mortgages and small business loans, US Senator Kirsten Gillibrand said at a summit in Washington, DC.

Speaking at the 2025 DC Blockchain Summit on March 26, the Democratic senator from New York praised her state for having some of the most robust financial regulations in the world, and said they should be adopted by all financial services sectors.

According to Gillibrand, these regulations need to be applied to stablecoin issuers, whether they are regulated at the state or federal levels, to ensure compliance with existing laws and to protect consumer safety. Gillibrand then turned her attention to protecting the banking industry:

“Do you want a stablecoin issuer to be able to issue interest, probably not, because if they are issuing interest, there is no reason to put your money in a local bank. If there is no reason to put your money in a local bank, who is going to give you a mortgage?

“If there is no deposit, small banks cannot do that anymore; it will collapse the financial services system that people rely on for their businesses and mortgages,” Gillibrand continued.

Senator Gillibrand speaking at a panel during the DC Blockchain Summit. Source: DC Blockchain Summit

Related: US stablecoin bill likely in ‘next 2 months’ — Trump’s crypto council head

Gillibrand is a co-sponsor of the GENIUS stablecoin legislation — a bill introduced by Senator Bill Hagerty in February that would establish a comprehensive regulatory framework for digital fiat tokens.

On March 10, Hagerty updated the bill to include stricter anti-money laundering provisions, know your customer (KYC) requirements, financial transparency regulations, and consumer protection controls.

The Senate Banking Committee advanced the GENIUS bill in an 18-6 vote on March 13. The bill must clear both chambers of Congress in floor votes before it hits US President Donald Trump’s desk for signing.

The GENIUS Act of 2025. Source: United States Senate

Critics of the GENIUS stablecoin bill say the legislation is a thinly veiled attempt to establish a central bank digital currency (CBDC) in the United States through privatized means.

Jean Rausis, co-founder of the decentralized trading platform Smardex, argued that centralized stablecoins provide avenues for financial censorship and state surveillance that could culminate in the government’s ability to turn off money or lock individuals out of the financial system.

Magazine: Unstablecoins: Depegging, bank runs and other risks loom

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