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Alzheimer’s Drug Discovery Foundation’s Diagnostics Accelerator (DxA) invests $10M in Alamar Biosciences, Inc. to Advance Precision Medicine in Alzheimer’s Disease

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Largest DxA investment to date supports development of Alamar’s ARGO™ DX System and future in vitro diagnostic tests

NEW YORK and FREMONT, Calif., Jan. 8, 2025 /PRNewswire/ — The Alzheimer’s Drug Discovery Foundation (ADDF)‘s Diagnostics Accelerator (DxA) today announced a $10M investment in Alamar Biosciences, Inc. This landmark investment, the largest in DxA history, will expedite the translation of the ARGO-HT research platform into an FDA-cleared system to support the development of in vitro diagnostic (IVD) tests – the gold standard of diagnostics. Alamar’s ARGO HT System automates high-throughput NULISA™ assays, offering ultrasensitive protein detection and multiplexing for analyzing blood-based biomarkers related to Alzheimer’s and other dementias.

“In cancer and other diseases of aging, we have biomarker panels that allow clinicians to better differentiate from many underlying causes of the disease and more importantly, how to tailor treatments based on each patient’s individual biomarker profile,” said Howard Fillit, MD, Co-Founder and Chief Science Officer at the ADDF. “There is a pressing need to have biomarker panels for Alzheimer’s patients so we can better diagnose and develop new treatments. Alamar’s innovative platform provides the opportunity for a first of its kind blood panel in Alzheimer’s, which will be an important step as we move forward to delivering a more personalized approach for patients.”

“The powerful combination of ultra-high sensitivity and multiplexing unlocks the potential to measure novel biomarker signatures, enabling differential diagnosis in neurodegeneration,” said Niranjan Bose, Managing Director, Health and Life Sciences at Gates Ventures. “The investment in the development of ARGO DX focuses on translating this capability onto a scalable platform for widespread clinical use. We are excited to partner with the Alamar team to bring this vision to reality and advance the molecular diagnostics landscape in Alzheimer’s disease.”

The holy grail for Alzheimer’s diagnostics is to develop an accessible and scalable blood panel that can detect multiple biomarkers, providing clinicians with a better understanding of each patient’s individual disease biology. Alamar’s NULISA™ technology is unique in that it enables ultra-high sensitivity with the ability to test for multiple targets at once.

“Experts in the field have showcased the performance of the NULISA technology in detecting essentially all the important biomarkers in blood for Alzheimer’s and related dementias,” said Yuling Luo, Ph.D., Founder, Chairman, and CEO of Alamar Biosciences, Inc. “The ARGO DX platform can potentially revolutionize the biomarker space by allowing researchers to go from discovery to detection of biomarker panels that stratify patient subsets and disease factors that would otherwise have gone unnoticed.”

“A diagnostic platform such as Alamar’s, that can detect and measure multiple disease pathways, will be instrumental in paving the way for early detection, biology of aging-based differential diagnosis, allowing for a precision medicine approach in Alzheimer’s,” commented Dr. Fillit.

This recent investment in Alamar reflects the DxA’s larger vision to accelerate the development of new biomarkers and diagnostic tools to enable early detection and diagnosis of Alzheimer’s. To date, the DxA has invested more than $80 million in nearly 70 projects, underscoring its commitment to bringing accessible, affordable, and scalable diagnostics to patients struggling with Alzheimer’s disease. Along with blood tests, the DxA’s diverse portfolio includes retinal scans and digital tools that will not only provide patients with early and accurate diagnoses but also work in tandem and have the potential to be used for screening, prognostic, and prevention efforts. 

About The Alzheimer’s Drug Discovery Foundation (ADDF)
Founded in 1998 by Leonard A. and Ronald S. Lauder, the Alzheimer’s Drug Discovery Foundation is dedicated to rapidly accelerating the discovery of drugs to prevent, treat and cure Alzheimer’s disease. The ADDF is the only public charity solely focused on funding the development of drugs for Alzheimer’s, employing a venture philanthropy model to support research in academia and the biotech industry. The ADDF’s leadership and contributions to the field have played a pivotal role in bringing the first Alzheimer’s PET scan (Amyvid®) and blood test (PrecivityAD®) to market, as well as fueling the current robust and diverse drug pipeline. Through the generosity of its donors, the ADDF has awarded more than $360 million to fund over 760 Alzheimer’s drug discovery programs, biomarker programs and clinical trials in 21 countries. To learn more, please visit: http://www.alzdiscovery.org/.

ABOUT THE DIAGNOSTICS ACCELERATOR (DxA)
The Diagnostics Accelerator, created in July 2018, is a $100 million global research initiative from partners including ADDF Co-Founder Leonard A. Lauder, Bill Gates, Jeff Bezos, MacKenzie Scott, the Dolby family, the Charles and Helen Schwab Foundation, The Association for Frontotemporal Degeneration, among others, to develop novel biomarkers for the early detection of Alzheimer’s disease and related dementias.

This research initiative is dedicated to accelerating the development of affordable and accessible biomarkers to diagnose Alzheimer’s disease and related dementias and advance the clinical development of more targeted treatments. Through translational research awards and access to consulting support from industry experts, this program will challenge, assist and fund the research community in both academia and industry to develop novel peripheral and digital biomarkers.

About Alamar Biosciences, Inc.
Alamar Biosciences is a privately held life sciences company with a mission to power precision proteomics to enable the earliest detection of disease. The company’s proprietary NULISA Platform along with the ARGO™ HT System work seamlessly with the latest advances in genomics to achieve single digit attomolar detection sensitivity, greatly surpassing the most sensitive protein detection technology on the market today. For more information, please visit alamarbio.com.

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SOURCE Alzheimer’s Drug Discovery Foundation

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SPEYSIDE COMPLETES ACQUISITION OF GSC

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Transaction enables Speyside to fuel the company’s next growth phase.

ANN ARBOR, Mich., Jan. 9, 2025 /PRNewswire/ — Speyside Equity Advisers (“Speyside”) announced that it has completed the acquisition of GSC Technologies, Inc. (“GSC”). The transaction will allow Speyside’s continued investment in GSC and fuel the company’s next growth phase. GSC is a leading manufacturer of plastic goods in North America.

“We are very excited about the GSC acquisition,” said Eric Wiklendt, Managing Director at Speyside. “GSC is similar to a great deal we did in a prior fund, with similar opportunities. GSC has a great growth and value-creation plan that we look forward to facilitating.”

GSC CEO Dave Barrow noted, “My team and I look forward to working with the Speyside team to execute our strategic plan. Speyside has a strong operational background that clearly differentiates it from other investment groups. The new capitalization structure and value-creation system that Speyside brings will help us achieve our vision and drive results.”

Nick Lardo, Managing Director at Speyside, noted, “GSC is our second closed deal in Speyside Equity Fund II. We are gaining strong momentum in the fund based on increased staff, AUM, and deal activity. We see 2025 as a year full of great opportunity.”

About Speyside
Speyside is a Detroit-based private equity firm. The firm invests in middle-market, buyout transactions in the manufacturing and value-added distribution sectors. Targeted portfolio companies often possess balance sheet, legal, environmental, labor, or transactional complexity. Speyside Equity focuses on creative transaction structures and is comfortable investing in carveouts of large multinational companies, industry consolidations, family-owned businesses, bankruptcies, workouts, and other special situations. Speyside takes an operational approach to creating value in these situations. Speyside has completed 37 investments. For more information, please visit speysideequity.com.

About GSC Technologies, Inc.
Founded in 1982 with a single plastic molding machine, GSC Technologies Inc. is a leading and groundbreaking manufacturer of plastic goods in North America focused on environmentally aware plastic solutions for organizing daily life today and in the future. Based in St-Jean-sur-Richelieu (Quebec/Canada), GSC designs and manufactures attractive, practical storage and organization lifestyle products for better modern living. With manufacturing plants that use contemporary equipment and technology and distribution facilities in the US, Canada, and China, GSC uses global testing and quality standards to ensure the best value, highest quality products. For more information, please visit gsctechnology.com.

Honigman LLP acted as Speyside’s legal advisor.

View original content to download multimedia:https://www.prnewswire.com/news-releases/speyside-completes-acquisition-of-gsc-302347022.html

SOURCE Speyside Equity

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Batteries Plus’s Strategic Partnerships Drive Nearly 130% Sales Increase

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Transformative Collaborations Fuels Record-Breaking Sales Growth for Batteries Plus FranchiseePartnerships Elevate Customer Experience, Expand Service OfferingsNew Jersey Franchisee’s Store Emerges as Top Repair Destination in Network

SPRINGFIELD, N.J., Jan. 9, 2025 /PRNewswire/ — Batteries Plus, the world’s leading specialty battery franchise, has achieved remarkable success through strategic partnerships with industry leaders in device protection and insurance. These collaborations have led to significant growth for franchisees over the last two years, as exemplified by Angel Cartagena’s store in Springfield, NJ.

Enhanced Customer Experience
By combining Batteries Plus’s extensive retail network and repair expertise with advanced mobile device protection programs from industry partners, Batteries Plus stores are equipped to handle subscribers’ phone protection needs, covering lost or damaged devices. This comprehensive approach has paved the way for improved customer satisfaction, ultimately increasing revenue for franchisees and strengthening brand loyalty overall.

“We’re not just fixing phones; we’re creating opportunities for customers to discover additional products and services they didn’t know they needed, from car batteries to key fobs,” Cartagena said. “This has contributed to increased ticket counts and higher margins across our business.”

Growth and Expansion
After serving with the U.S. Air Force for 37 years, Cartagena began franchising with Batteries Plus in 2008. In the 18 years since, his store has grown to become the top-performing location for repairs in the entire Batteries Plus network, with repair volumes nearly 50% higher than other stores.

Since implementing these strategic partnerships, Cartagena’s Batteries Plus location has experienced unprecedented growth:

217.7% increase in device repair sales year-over-year128.6% increase in total business sales year-over-year147.8% increase in average ticket value year-over-year10.6% increase in gross profit year-over-year

The success of these partnerships has led to significant expansion for Cartagena’s store, necessitating the hiring of three additional team members to help manage the increased volume.

“These strategic partnerships have been transformative for our business,” said Cartagena. “We’ve seen a dramatic increase in customer traffic and sales, particularly in our device repair services. These collaborations have not only boosted our bottom line but also enhanced our ability to serve our community with top-notch repair solutions. It’s been great for business, allowing us to expand our team and offer more comprehensive services to our customers.”

Batteries Plus has become a global leader in supplying the battery needs of its customers for cars, boats, phones, key fobs and more. With over 800 store locations in operation and development nationwide, Batteries Plus has also carved out a unique niche in the industry with its ‘plus’ services – including cell phone repair and key fob replacement. Positioned for the battery-powered future, Batteries Plus was ranked on Franchise Times Top 400 list, coming in at #130. Plus, for the 30th year in a row, the brand ranked on Entrepreneur Magazine’s Franchise 500 list, climbing 53 spots over last year’s rank and even becoming one of only 49 franchise brands to be inducted into Entrepreneur’s Franchise 500 Hall of Fame.

To learn more about Batteries Plus, visit batteriesplusfranchise.com.

ABOUT BATTERIES PLUS: Batteries Plus, founded in 1988 and headquartered in Hartland, WI, is a leading omnichannel retailer of batteries, specialty light bulbs and phone repair services for the direct-to-consumer and commercial channels. The retailer also offers key programming, replacement and cutting services. Through a nationwide network of stores, the company offers a differentiated value proposition of unrivaled product selection, in-stock availability and customer service. Batteries Plus is owned by Freeman Spogli, a private equity firm based in Los Angeles and New York City. To learn more about one of Forbes®’ Best Franchises to Buy in America, visit https://www.batteriesplusfranchise.com.  

MEDIA CONTACT: Cole Koretos, Fishman Public Relations, ckoretos@fishmanpr.com or 847-331-1190

View original content to download multimedia:https://www.prnewswire.com/news-releases/batteries-pluss-strategic-partnerships-drive-nearly-130-sales-increase-302347179.html

SOURCE Batteries Plus

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MobileX Partners with Ethika to Launch ‘ethikaX,’ Merging Style with Mobile Connectivity

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 LAS VEGAS, Jan. 9, 2025 /PRNewswire/ — Today at CES, MobileX, the most customizable wireless service designed to save consumers money, and Ethika, a leading lifestyle brand driven by personal identity, announced an exciting new collaboration. Together, the two companies will be launching “ethikaX” – a collection that seamlessly merges mobile-friendly design with bold self-expression and dynamic style. This partnership represents a groundbreaking moment where mobile meets fashion, blending cutting-edge technology with style and originality.

The ethikaX line will debut in Q1 2025, featuring a range of apparel and accessories tailored for the modern, mobile lifestyle. The initial collection will include hoodies and t-shirts with phone-friendly pockets, phone cases, and even a limited-edition set of ethikaX-branded headphones.

“At MobileX, we’re passionate about empowering our customers to live untethered, connected lives,” said Peter Adderton, CEO of MobileX. “By partnering with Ethika, we’re able to bring that vision to life through thoughtfully designed apparel that embraces uniqueness and creativity while seamlessly integrating with our mobile services.”

Ethika’s commitment to celebrating individuality and self-expression across diverse cultures including motorsports, BMX, music, art and fashion aligns perfectly with MobileX’s mission to empower consumers through customizable, user-focused mobile service that ensures they only pay for what they use. The ethikaX collection will be available for purchase through the MobileX app and website, as well as select Ethika retail partners. Customers can also sign up for MobileX at these retail locations by purchasing a SIM Kit or scanning a QR code and activating with eSIM.

“We’re thrilled to be working with the innovative team at MobileX to redefine the intersection of mobile and fashion,” said Matt Cook, CEO of Ethika. “This collaboration allows us to extend the Ethika brand into new territories while continuing to celebrate those who stand out from the crowd and share our core values of quality, style and originality.”

Stay tuned for updates on ethikaX’s launch in Q1 2025 here.

 About MobileX
Headquartered in Orange County, California, MobileX is the world’s most customizable mobile carrier delivering the ultimate in choice and cost control. MobileX is a unique service that uses artificial intelligence to predict how much data customers need, dramatically reducing costs while ensuring reliable speed and service. MobileX was founded by Peter Adderton, who also founded both Boost Mobile and Digital Turbine. For more information, please visit mymobilex.com.

 About Ethika
Ethika is a leading lifestyle brand which started in San Clemente, CA and is now based in Lake Forest. Since the inception of the brand, Ethika and its team have been determined to live life, innovate, and deliver quality products, while staying true to the brand’s biggest asset – the FAMILIE. Ethika employees, friends, athletes, artists and customers are the core of the brand and the reason Ethika exists. More Ethika news, photos, and videos can be found on X (@ethika), Instagram (@ethika), and online at www.ethika.com.

Press contact:
Illume PR for MobileX
mobilex@illumepr.com

View original content to download multimedia:https://www.prnewswire.com/news-releases/mobilex-partners-with-ethika-to-launch-ethikax-merging-style-with-mobile-connectivity-302346661.html

SOURCE Mobile X Global, Inc.

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