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New England Biolabs® Launches EM-seq™ v2, an updated kit for more sensitive detection of 5mC and 5hmC

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This bisulfite-free method of methylation detection is updated with a faster, more streamlined workflow that enables highly sensitive methylation analysis with as little as 100 pg input.

IPSWICH, Mass., Jan. 6, 2025 /PRNewswire/ — New England Biolabs (NEB®) announces the launch of EM-seq™ v2, a high-performance enzyme-based alternative to bisulfite sequencing for the identification of 5mC and 5hmC. The enzyme-based conversion workflows for EM-seq and E5hmC-seq avoid the pitfalls of whole genome bisulfite treatment, including DNA damage that results in fragmentation, loss and bias. The newly updated kit delivers improved performance for wider input range (100 pg to 200 ng), and a faster, more streamlined workflow as compared to the original EM-seq kit.

“EM-seq v2 will be particularly valuable for researchers working in clinical research and epigenetics who often face challenges sequencing samples less than 10 ng that are below the input range of bisulfite sequencing and our original EM-seq kit,” says Andrew Barry, Associate Director of Product Portfolio Management for NEB’s sequencing product line. “The kit’s high-quality data from low input samples will enable researchers to get improved data for the same amount of sequencing, or similar data with less sequencing.”

Key improvements in EM-seq v2 include:

Substantially Lower DNA Input: The minimum input requirement has been reduced from 10 ng to 100 picograms, making EM-seq v2 suitable for applications with limited sample availability.Streamlined Workflow: EM-seq v2 features a faster incubation step and eliminates a cleanup step, resulting in a time savings of approximately 30-45 minutes.Improved Performance: The kit delivers enhanced data quality, with greater mapping efficiency, more even GC coverage and detection of more CpGs with fewer sequence reads.

“As an ISO 17025 accredited laboratory, we need reliable and reproducible kits and protocols,” says Dr. Marta Gut, Head of the Sequencing Unit at Centro Nacional de Análisis Genómico (CNAG) in Barcelona, Spain. “After thorough benchmarking of NEBNext Enzymatic Methyl-Seq v2 interrogating 5mC, the standard bisulfite conversion method lost its reference status for our methylation analyses. NEBNext EM-seq v2 and the NEBNext E5hmC-seq Kit for detecting 5hmC specifically, are now our methods of choice to study both modifications.”

EM-seq v2 is compatible with automation for easy scale-up and with 5hmC-seq for specific detection of 5hmC. Indexing primers are now supplied separately, providing greater flexibility for multiplexing samples. For further streamlining, enzymatic fragmentation of DNA compatible with EM-seq and E5hmC-seq workflows can be achieved using NEBNext UltraShear®.

The original EM-seq kit is not being discontinued at this time. More details and extensive performance data can be found at www.NEBNext.com

About New England Biolabs

For 50 years, New England Biolabs (NEB) has pioneered the discovery and production of innovative products tailored for molecular biology research. Our commitment to scientific discovery is evident in all that we do, including our ever-expanding product portfolio, investment in our basic and applied research program, and support of customers’ research in academia and industry, including cutting-edge technologies for use in molecular diagnostics and nucleic-acid vaccines development. Guided by our founding principles, NEB proactively invests in efforts to improve the well-being of our employees, surrounding communities, as well as the future of our planet. NEB remains a privately held company with global reach, supported by our headquarters in Ipswich, MA, USA, subsidiary offices in 10 countries, and over 60 distribution partners around the world. For more information about New England Biolabs, visit www.neb.com.

NEB®, NEW ENGLAND BIOLABS® and NEBNEXT ULTRASHEAR® are registered trademarks of New England Biolabs, Inc.
EM-Seq™ is a trademark of New England Biolabs, Inc.

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SOURCE New England Biolabs, Inc.

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Morrison Foerster Opens Amsterdam Office, Extending the Reach of Its Premier Privacy + Data Security Practice

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The firm’s 18th office worldwide and 4th in Europe, will create deeper connections with global clients.

AMSTERDAM, Netherlands, Jan. 8, 2025 /PRNewswire-PRWeb/ — Morrison Foerster (MoFo), a leading global law firm, is pleased to announce that it has opened an office in Amsterdam to further extend the reach of its premier Privacy + Data Security practice, and forge deeper connections with global clients operating in Europe.
The office is the firm’s 18th globally and 4th in Europe, and will be led by partner Alex van der Wolk, co-chair of MoFo’s preeminent Global Privacy & Data Security practice. Initially, the office will include van der Wolk, partner Marijn Storm, and senior of counsel Lokke Moerel, all admitted to practice in the Netherlands, with further additions to the office expected following the office’s formal opening.

MoFo’s new Amsterdam office enables the firm to further entrench its roots with disputes and transactions clients globally and in the European market, offering closer and more strategic ties with clients that the firm is already advising in the Netherlands, alongside the opportunity to forge new relationships.

“Establishing a presence in the Netherlands creates an exciting proposition for clients as we grow Morrison Foerster’s global platform,” said Eric McCrath, Chair of Morrison Foerster. “Amsterdam represents a thriving, multi-industry hub, with many of the globe’s biggest corporations present in the city alongside innovative new startups and scale-ups. The founder members of our Amsterdam office have been practicing in the Netherlands for many years and already have an established network in the region, affording us a running start as we open our newest office in the MoFo network. We are excited at what Amsterdam can bring to our platform and look forward to the success of our newest office.”

The firm’s Amsterdam office will look to build on its strong Privacy + Data Security practice, advising a cross-section of companies in the technology, life sciences, and artificial intelligence industries.

“Having advised numerous Netherlands-based clients for many years, I am excited to lead our new office in Amsterdam, welcoming existing and new clients to Morrison Foerster’s premier global platform for data privacy and security matters,” said van der Wolk. “Our team in Amsterdam, with market-leading attorneys in data privacy, will not only lead on complex work in their own right, but are also play a crucial role on an array of the firm’s global mandates, from cross-border disputes to billion-dollar deals. I am excited to build the firm’s 18th office in its global network.”

Media Contact

Alexander Smith, Morrison Foerster, +44 (20) 79204064, alexandersmith@mofo.com, mofo.com

View original content:https://www.prweb.com/releases/morrison-foerster-opens-amsterdam-office-extending-the-reach-of-its-premier-privacy–data-security-practice-302345915.html

SOURCE Morrison Foerster

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AmpUp and Hubject Join Forces to Accelerate EV Charging Across North America

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New collaboration to introduce Plug&Charge technology, followed by expanded access through the eRoaming network

SANTA CLARA, Calif., Jan. 8, 2025 /PRNewswire/ — AmpUp, a leading provider of electric vehicle (EV) charging solutions, and Hubject, the global leader in eRoaming and Plug & Charge services, today announced a partnership aimed at accelerating the EV charging experience across North America.

Under this collaboration, AmpUp will first implement Hubject’s Plug&Charge technology across its new charging stations. This innovative feature simplifies charging by allowing EV drivers to initiate payment without relying on app-based methods or RFID cards. Following this rollout, AmpUp’s charging stations will be integrated into Hubject’s extensive eRoaming network, providing seamless access to over 1 million charging points globally.

“Charger availability and ease of use are vital for making the EV transition accessible to all,” said Tom Sun, CEO and co-founder of AmpUp. “By partnering with Hubject, we are committed to enhancing the charging experience for our customers while expanding charging opportunities in their communities.”

Key benefits of the partnership include:

Plug&Charge Implementation: A simplified payment process for EV drivers.Access to a Vast Network: Integration into Hubject’s global network of over 1 million charging points.Enhanced Interoperability: Ensures driver choice and access to charging infrastructure across borders.

Trishan Peruma, Hubject North America CEO, said, “We welcome AmpUp as a valued partner in the Hubject eMobility ecosystem as we look to provide a seamless and secure charging experience for even more drivers across North America.”

The partnership between AmpUp and Hubject marks a pivotal advancement in expanding reliable and user-friendly EV charging infrastructure across the continent. Together, the companies are driving toward a future where sustainable transportation is accessible to everyone.

About AmpUp
AmpUp is breaking down barriers to widespread EV adoption with the most reliable, flexible, and user-friendly EV charging platform. Since its founding in 2018, AmpUp has powered over 1,500 charging networks across 75 North American markets, enabling businesses and property owners to seamlessly deploy and manage EV charging solutions. Trusted by industry leaders such as JLL, CBRE, Domino’s Pizza, Goodyear, Under Armour, and Hilton, AmpUp is at the forefront of advancing sustainable transportation. For more information, visit www.ampup.io. For marketing inquiries, please contact randa@ampup.io

About Hubject
Hubject simplifies the charging of electric vehicles. Through its eRoaming platform intercharge, the eMobility specialist connects Charge Point Operators (CPOs) and eMobility Service Providers (EMPs) to provide standardized access to charging infrastructure regardless of any network. Hubject has established the world’s largest cross-provider charging network for electric vehicles by connecting CPO networks encompassing over 1 million connected charging points and more than 2,250 B2B partners across 63 countries and four continents. In addition, Hubject is a trusted consulting partner in the Mobility market, advising automotive manufacturers, charging providers, and other EV-related businesses looking to launch eMobility services or implement Plug&Charge using ISO15118-2 and ISO15118-20. In essence, Hubject promotes eMobility and its advancement worldwide. For more information, please visit www.hubject.com follow us on LinkedIn.

 

View original content to download multimedia:https://www.prnewswire.com/news-releases/ampup-and-hubject-join-forces-to-accelerate-ev-charging-across-north-america-302345957.html

SOURCE AmpUp

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Therap Services Strengthens Documentation with Advanced HIPAA-Compliant Secure Video Documentation Tool

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TORRINGTON, Conn., Jan. 8, 2025 /PRNewswire/ — Therap Services, the national leader in HIPAA-compliant electronic documentation solutions for organizations in the Long-Term Services and Supports (LTSS), Home and Community-Based Services (HCBS), and other human services industries, strengthens its documentation capabilities with the Secure Video Documentation tool and giving service providers a highly secure and HIPAA-compliant solution for managing videos containing Protected Health Information (PHI). This tool is designed to meet the needs of organizations that require efficient, secure, and integrated video documentation within their workflows.

The Secure Video Documentation tool allows users to upload and store videos in a centralized Video Library. These videos can be attached directly to existing modules within the Therap system, including General Event Reports (GER), GER Resolution, Individual Home Page, ISP Program, and T-Logs. This integration strengthens the documentation process by enabling providers to enhance traditional records with video evidence, improving both the clarity and comprehensiveness of reports.

Therap’s solution ensures that PHI-related video content is managed in a secure environment, with access strictly controlled through user privilege assignments. Based on their roles, users can view or download videos as needed, supporting collaborative workflows while safeguarding sensitive data. This functionality aligns with Therap’s commitment to privacy and security, ensuring that service providers can meet regulatory requirements while improving care and operational efficiency.

Designed specifically for service providers, the Secure Video Documentation tool is an invaluable resource for documenting incidents. By integrating video content into their systems, organizations can achieve better communication, more detailed documentation, and greater accountability in their service delivery.

The availability of this tool highlights Therap’s dedication to providing innovative and practical solutions for the human services sector. Service providers using the Therap system now have a reliable and secure way to incorporate video documentation into their processes, further enhancing their ability to deliver high-quality care while maintaining compliance with privacy regulations.

For more information on Therap’s HIPAA Compliant Secure Video Streaming, please visit:
https://www.therapservices.net/products/hipaa-compliant-video-storage/

About Therap

Therap’s comprehensive and HIPAA-compliant software is used in human services settings for documentation, communication, reporting, EVV and billing.

Learn more at  www.therapservices.net.

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http://www.therapservices.net

View original content:https://www.prnewswire.com/news-releases/therap-services-strengthens-documentation-with-advanced-hipaa-compliant-secure-video-documentation-tool-302345921.html

SOURCE Therap Services

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