Connect with us

Technology

CS Genetics Unveils SimpleCell™: A New Era in Single-Cell Genomics

Published

on

Single-cell genomics made simple, scalable, and seamless

DENVER, Nov. 6, 2024 /PRNewswire/ — CS Genetics, a leader in next-generation single-cell genomics, today announced the launch of SimpleCell™ 3′ Gene Expression kits, its first commercial offering designed for accessible and scalable single-cell transcriptomics.

The SimpleCell™ platform leverages Kinetic Confinement – a groundbreaking molecular process – to deliver the most accessible, instrument-free, and scalable solution in single-cell genomics.

Luke Edelman, Founder and Chief Technology Officer at CS Genetics, remarked, “After several years of development, we are so excited to be releasing our first SimpleCell™️ products commercially. Single cell is a very important and impactful modality for biological measurement, and we feel strongly that a diverse ecosystem of technology platforms – now including Kinetic Confinement and SimpleCell™️ – is good for the field and for the cadence of discovery. It’s a privilege to be sharing our work with the scientific community, and we are totally stoked to see how customers start using it.”

Key features of the SimpleCell™️ 3′ Gene Expression kits include:

Workflow: Single-day cells-to-sequencer workflow, using only standard lab equipment and pipettingCost-effectiveness: Under $500 per sample, regardless of experiment scale or purchase volumeSample compatibility: Supports blood/PBMCs, cell lines, disaggregated solid tissues, and more

The company is presenting details about Kinetic Confinement technology and the SimpleCell™️ product line at the 2024 Annual Meeting of the American Society for Human Genetics in Denver. Visit CS Genetics at booth 402 and join the SimpleCell™ CoLab talk on Wednesday, November 6, at 4:00 PM in Theater 3 to explore the future of single-cell genomics.

Charlly Kao, Principal Scientist at the Center for Applied Genomics (CAG) at the Children’s Hospital of Philadelphia and an early SimpleCell™️ customer remarked, “We’ve been eagerly waiting for something like SimpleCell™️ that can perform single-cell transcriptome profiling in a flexible, instrument-free, and simple-to-use workflow at a more attractive price point. Our evaluation of the platform showed it was able to successfully profile sample types at the single-cell level within our biorepository, and we now look forward to adopting SimpleCell™️ more broadly both for our own research and as a shared tool with researchers across our ecosystem as a service offering through the CAG Core.”

Hákon Hákonarson, Director of the Center for Applied Genomics at the Children’s Hospital of Philadelphia, and Professor of Pediatrics at the Perelman School of Medicine, remarked, “Kinetic Confinement and the SimpleCell™️ platform are timely new additions to the single cell universe. As a translational research facility with access to a very large number of clinical specimens, we are particularly excited about the opportunities presented by the platform to enable significantly larger-scale single cell studies than has been realistically possible with other tools.”

Yuriy Alekseyev, director of the Single Cell and NGS core laboratory at the Boston University Chobanian & Avedisian School of Medicine, commented, “In the core lab setting, we see researchers who need more affordable, flexible, and easy-to-use options for single cell analysis. SimpleCell™️ checks these boxes well. It’s simple to set up, cost-effective, and a welcome addition for users who’ve been looking for a platform that doesn’t require a huge learning curve or large costs for each experiment. Even our less-experienced technician performed this protocol for the first time and obtained great results.”

The SimpleCell™️ 3′ Gene Expression kits are available in 8-sample and 16-sample sizes. Now accepting orders for shipment across the U.S., U.K., Europe, and select global regions. Visit www.csgenetics.com to learn more or place an order.

About CS Genetics
CS Genetics is a privately held genomics-technology company based in San Diego, California and Cambridge, UK. The company has developed a radically new, instrument-free platform for single-cell genomics with disruptive simplicity, speed, and scalability that will launch a new era of NGS-based cellular analysis. The company’s technology leverages a molecular process known as Kinetic Confinement that is categorically different to other single cell technologies, and plugs seamlessly into standard, widespread lab infrastructure. The company holds a large global intellectual property estate covering its single cell platform and related reagent, workflow, manufacturing and application technologies. For more information, visit www.csgenetics.com.

Media Contact:
Shannon Wilsey
CS Genetics PR
info@csgenetics.com

View original content to download multimedia:https://www.prnewswire.com/news-releases/cs-genetics-unveils-simplecell-a-new-era-in-single-cell-genomics-302297777.html

SOURCE CS Genetics

Continue Reading
Click to comment

Leave a Reply

Your email address will not be published. Required fields are marked *

Technology

Jereh Showcases Digitalized Exhibit at ADIPEC 2024, Highlighting Smart, Sustainable Energy Solutions

Published

on

By

ABU DHABI, UAE, Nov. 7, 2024 /PRNewswire/ — Amidst a year of expansion and technological breakthroughs, Jereh brings a dynamic showcase to ADIPEC 2024. Pushing the boundaries of high-end engineering and equipment, Jereh is highlighting innovations in efficient oil & gas development, surface engineering, digital oilfield technologies and oilfield environmental management that resonate with a industry eager for greener and smarter solutions.

Showcasing a range of digital innovations, Jereh’s booth drew a large crowd eager to explore its advanced solutions. Distinguished visitors included His Excellency Omar Suwaina AlSuwaidi, Undersecretary at the UAE Ministry of Industry and Advanced Technology. This year also marks the 40th anniversary of diplomatic relations between China and the UAE, and Jereh had the honor of hosting Chinese Ambassador to the UAE, Zhang Yiming, at its booth.

As industries and governments intensify their focus on AI, its ability to tackle major challenges and shape the future of energy becomes increasingly clear. In response, ADIPEC 2024 has introduced a dedicated Energy AI Zone, specifically designed to explore how artificial intelligence can drive innovations and efficiency within the energy landscape.

Aligned with this trend, Jereh’s commitment to digital transformation becomes a major draw for ADIPEC visitors this year. Jereh’s Gas-Powered Electric Fracturing Solution features a 35MW gas turbine generator, electric frac trailers, an intelligent manifold system, and a smart command center for comprehensive site support. Its solutions, from remote equipment control to predictive maintenance, is able to create a decision-making model that ensures rapid, expert responses to any anomalies. This fully electric, smart site allows one-click operations from the command center, reducing the workforce from eight operators to three.

Expanding its digital expertise, Jereh also provides integrated digital solution for smart oil & gas fields engineering. On the second day of ADIPEC, Jereh signed a $920 million EPC contract with ADNOC Onshore to execute a transformative AI-powered well digitalization program. Under this contract, Jereh will install advanced remote sensing and operational equipment in over 2,000 wells across various fields. The project will enable real-time data transmission, monitoring, and analysis across these wellsites, helping ADNOC transition from traditional inspection methods to an advanced, fully digitalized, and largely autonomous management model.

Through its digitalized innovations and strategic partnerships, Jereh demonstrates its commitment to pioneering the energy industry. As ADIPEC 2024 underscores, Jereh is not only meeting current energy demands with sustainable solutions but is actively shaping a more resilient, data-driven, and efficient energy future.

Photo – https://mma.prnewswire.com/media/2550178/Jereh_ADIPEC_2024_BOOTH10410.jpg

Photo – https://mma.prnewswire.com/media/2550179/Jereh_ADIPEC2024.jpg

View original content:https://www.prnewswire.co.uk/news-releases/jereh-showcases-digitalized-exhibit-at-adipec-2024-highlighting-smart-sustainable-energy-solutions-302298144.html

Continue Reading

Technology

Digital Realty Trust, L.P. Announces Pricing of $1.0 Billion Exchangeable Senior Notes Offering

Published

on

By

AUSTIN, Texas, Nov. 6, 2024 /PRNewswire/ — Digital Realty Trust, Inc. (NYSE: DLR), (“Digital Realty”), the largest global provider of cloud- and carrier-neutral data center, colocation, and interconnection solutions, today announced that its subsidiary, Digital Realty Trust, L.P. (“Digital Realty L.P.”), priced its offering of $1,000,000,000 aggregate principal amount of 1.875% exchangeable senior notes due 2029 (the “notes”) in a private offering to qualified institutional buyers pursuant to Rule 144A under the Securities Act of 1933, as amended (the “Securities Act”). Digital Realty will fully and unconditionally guarantee the notes on a senior, unsecured basis. The issuance and sale of the notes are scheduled to settle on November 12, 2024, subject to customary closing conditions. Digital Realty L.P. also granted the initial purchasers of the notes an option to purchase, for settlement within a period of 13 days from, and including, the date the notes are first issued, up to an additional $150,000,000 principal amount of notes.

The notes will be senior, unsecured obligations of Digital Realty L.P. and will accrue interest at a rate of 1.875% per annum, payable semi-annually in arrears on May 15 and November 15 of each year, beginning on May 15, 2025. The notes will mature on November 15, 2029, unless earlier repurchased, redeemed or exchanged. Before August 15, 2029, noteholders will have the right to exchange their notes only upon the occurrence of certain events. From and after August 15, 2029, noteholders may exchange their notes at any time at their election until the close of business on the second scheduled trading day immediately before the maturity date. Digital Realty L.P. will settle exchanges in cash and, if applicable, shares of Digital Realty’s common stock. The initial exchange rate is 4.7998 shares of Digital Realty’s common stock per $1,000 principal amount of notes, which represents an initial exchange price of approximately $208.34 per share of Digital Realty’s common stock. The initial exchange price represents a premium of approximately 20.0% over the last reported sale price of $173.62 per share of Digital Realty’s common stock on November 6, 2024. The exchange rate and exchange price will be subject to adjustment upon the occurrence of certain events.

The notes will be redeemable, in whole or in part (subject to certain limitations), for cash at Digital Realty L.P.’s option at any time, and from time to time, on or after November 22, 2027 and on or before the 40th scheduled trading day immediately before the maturity date, but only if the last reported sale price per share of Digital Realty’s common stock exceeds 130% of the exchange price for a specified period of time and certain other conditions are satisfied. The redemption price will be equal to the principal amount of the notes to be redeemed, plus accrued and unpaid interest, if any, to, but excluding, the redemption date.

If certain corporate events that constitute a “fundamental change” occur, then, subject to a limited exception, noteholders may require Digital Realty L.P. to repurchase their notes for cash. The repurchase price will be equal to the principal amount of the notes to be repurchased, plus accrued and unpaid interest, if any, to, but excluding, the applicable repurchase date.

The notes will be entitled to the benefits of a registration rights agreement pursuant to which Digital Realty will agree to register, under the Securities Act, the resale of the shares of Digital Realty’s common stock, if any, issuable upon exchange of the notes within specified time periods and subject to certain limitations.

Digital Realty L.P. estimates that the net proceeds from the offering will be approximately $979.3 million (or approximately $1,126.8 million if the initial purchasers fully exercise their option to purchase additional notes), after deducting the initial purchasers’ discounts and commissions and Digital Realty L.P.’s estimated offering expenses. Digital Realty L.P. intends to use the net proceeds from the offering to temporarily repay borrowings outstanding under its global revolving credit facilities, acquire additional properties or businesses, fund development opportunities, and to provide for working capital and other general corporate purposes, including potentially for the repayment of other debt or the repurchase, redemption, or retirement of outstanding debt securities, or a combination of the foregoing.

The offer and sale of the notes, the guarantee and any shares of Digital Realty’s common stock issuable upon exchange of the notes have not been registered under the Securities Act or any other securities laws, and the notes and any such shares cannot be offered or sold except pursuant to an exemption from, or in a transaction not subject to, the registration requirements of the Securities Act and any other applicable securities laws. Although Digital Realty L.P. and Digital Realty will enter into a registration rights agreement pursuant to which Digital Realty will agree to register, under the Securities Act, the resale of the shares of Digital Realty’s common stock, if any, issuable upon exchange of the notes, the registration rights agreement will contain significant limitations, and a resale registration statement may not be available at the time investors wish to resell the shares of Digital Realty’s common stock, if any, issuable upon exchange of their notes. This press release does not constitute an offer to sell, or the solicitation of an offer to buy, the notes or any shares of Digital Realty’s common stock issuable upon exchange of the notes, nor will there be any sale of the notes or any such shares, in any state or other jurisdiction in which such offer, sale or solicitation would be unlawful.

About Digital Realty
Digital Realty brings companies and data together by delivering the full spectrum of data center, colocation and interconnection solutions. PlatformDIGITAL®, the company’s global data center platform, provides customers with a secure data meeting place and a proven Pervasive Datacenter Architecture (PDx®) solution methodology for powering innovation and efficiently managing Data Gravity challenges. Digital Realty gives its customers access to the connected data communities that matter to them with a global data center footprint of 300+ facilities in 50+ metros across 25+ countries on six continents.

Investor Relations
Jordan Sadler / Jim Huseby
Digital Realty
+1 415 275 5344
InvestorRelations@digitalrealty.com

Safe Harbor Statement
This press release includes forward-looking statements, including statements regarding the completion of the offering and the expected amount and intended use of the net proceeds. Forward-looking statements represent Digital Realty’s current expectations regarding future events and are subject to known and unknown risks and uncertainties that could cause actual results to differ materially from those implied by the forward-looking statements. Among those risks and uncertainties are market conditions, the satisfaction of the closing conditions related to the offering and risks relating to Digital Realty’s business, including those described in periodic reports that Digital Realty files from time to time with the SEC. Digital Realty L.P. may not consummate the offering described in this press release and, if the offering is consummated, cannot provide any assurances regarding its ability to effectively apply the net proceeds as described above. The forward-looking statements included in this press release speak only as of the date of this press release, and neither Digital Realty nor Digital Realty L.P. undertakes to update the statements included in this press release for subsequent developments, except as may be required by law.

View original content to download multimedia:https://www.prnewswire.com/news-releases/digital-realty-trust-lp-announces-pricing-of-1-0-billion-exchangeable-senior-notes-offering-302298154.html

SOURCE Digital Realty Trust

Continue Reading

Technology

Western Sydney University and MindChamps join forces to transform early childhood education

Published

on

By

SINGAPORE, Nov. 7, 2024 /PRNewswire/ — Western Sydney University and MindChamps have announced a Memorandum of Understanding (MoU) aimed at revolutionising early childhood education, enhancing workforce development, and fostering global pathways for education.

This collaboration harnesses the University’s research expertise and maximises MindChamps’ over a quarter of a century of research, teaching methodology and groundbreaking education pedagogy to elevate learning standards in Australia and globally.

The partnership builds on MindChamps’ research-backed approach which has been hailed as the Education Movement of the 21st Century by No. 1 New York Times and Wall Street Journal bestselling author, Dr Joseph A. Michelli.

Western Sydney University Vice-Chancellor and President, Distinguished Professor George Williams AO, emphasised the transformative potential of the partnership to drive educational innovation and make quality early childhood education accessible.

“Collaborating with MindChamps will allow us to nurture the next generation of early childhood educators, provide tailored educational pathways, and address workforce shortages,” said Distinguished Professor Williams.

“By combining research and practical training, we’re creating a unique platform that supports both students and communities, fostering a brighter future for early learners and educators alike.”

MindChamps Founder and CEO, Mr David Chiem, highlighted the partnership’s shared vision of holistic education.

“From the very beginning we set out in our Social Charter our intention ‘to challenge and lift education standards globally and to provide educational opportunities to those who would not otherwise have the means.’ With this partnership with Western Sydney University we will advance early childhood education with groundbreaking research, arts integration, and real-world training that prepares educators to meet the demands of a rapidly changing educational landscape and a world that is being transformed by Artificial Intelligence.”

“At MindChamps, our revolutionary 3-Mind Education Model – the Champion, Learning and Creative Mind, nurtures children’s Champion, Learning and Creative Minds through a unique curriculum crafted by global leaders in the four domains of Education, Psychology, Neuroscience and Theatre. We are thrilled to collaborate with the University to lift education standards globally, and provide the means for world class education.”

About MindChamps

“MindChamps is the Global Education Movement of the 21st Century.

While the companies featured in my prior books, Mercedes-Benz, The Ritz-Carlton Hotel Company and Starbucks demonstrate impressive brand power, none have been in a position to fundamentally shape society on par with MindChamps.”
Dr Joseph A. Michelli
No. 1 New York Times & Wall Street Journal Bestselling Author

While there are thousands of education brands across the world, only one:

Is hailed as a Global Education Movement by No. 1 New York Times and Wall Street Journal bestselling author, Dr Joseph A. Michelli.Has successfully created a breakthrough education methodology that has attained patent programme status across three continents – the US, UK and Australia.Has world-renowned neuroscientist Emeritus Professor Allan Snyder, Fellow of the Royal Society and Marconi Prize Winner as its Chancellor and Chair of the MindChamps Global Research, Advisory & Programme Development Team, comprising of award-winning, world-leading experts in the 4 Domains of ● Education ● Psychology ● Neuroscience ● TheatreHas created the revolutionary 3-Mind Education Model – the Champion, Learning and Creative Mind.Has a proprietary Reading & Writing programme backed by research, producing over 200 eBooks.Has the proven Optimal Flow MethodTM and Art of Learning techniques, along with Champion Mindset coaching, which have enabled students to achieve up to 6 grade improvements in English, Maths, Science and Chinese, as verified by Forvis Mazars, a leading internationally integrated partnership, specialising in audit, accountancy, advisory and tax services.*Has been accorded the WIPO-IPOS IP Award by the World Intellectual Property Organization for excellence in the brand’s Trademark Portfolio.Requires all its teachers to undergo up to 200 hours of professional training and accreditation, regardless of previous teaching experience or qualifications.Has its research and education philosophy published in 6 bestselling books by major world publishing houses.Nurtures every child to face the unpredictable world with the mindset of 100% Respect and Zero Fear!

*The results have been verified by Forvis Mazars LLP (fka Mazars LLP) in Singapore to supporting records provided by the Company, based on specified procedures in accordance with the Singapore Standard on Related Services SSRS 4400 Engagements to Perform Agreed-upon Procedures Regarding Financial Information.

 

View original content to download multimedia:https://www.prnewswire.com/apac/news-releases/western-sydney-university-and-mindchamps-join-forces-to-transform-early-childhood-education-302297478.html

SOURCE MindChamps Education Group

Continue Reading

Trending