Technology

APA POLL: FUTURE OF NATION, ECONOMY AND PRESIDENTIAL ELECTION TOP U.S. STRESSORS

Published

4 hours ago

October 22, 2024

Most U.S. adults concerned about political violence, end of democracy

WASHINGTON, Oct. 22, 2024 /PRNewswire/ — More than 7 in 10 adults said the future of the nation (77%) is a significant source of stress in their lives, with the economy (73%) and the 2024 U.S. presidential election (69%) following closely behind, according to the latest Stress in America™ survey released today by the American Psychological Association.

People have faced a political climate that is highly charged, which has led to the erosion of civil discourse.

At the same time, the poll found many common stressors among people with different political party affiliations. The survey was conducted by The Harris Poll on behalf of APA among more than 3,000 U.S. adults age 18+ between Aug. 1 and 23, 2024.

Compared with the previous two U.S. presidential elections, stress related to the election was similar to 2020 (69% vs. 68%) but significantly higher than in 2016 (52%). What sets the 2024 poll apart from previous APA election surveys is the collective stress about the potential fallout from the election results: More than 7 in 10 adults (72%) said they are worried the election results could lead to violence, and more than half of adults (56%) said they believed the 2024 presidential election could be the end of democracy in the U.S. Meanwhile, around a third of adults (32%) said the political climate has caused strain among themselves and their family members, with (30%) who said they limit their time with family because they don’t share the same values.

“For nearly a decade, people have faced a political climate that is highly charged, which has led to the erosion of civil discourse and strained our relationships with our friends and our families. But isolating ourselves from our communities is a recipe for adding more stress to our lives,” said APA CEO Arthur C. Evans Jr., PhD. “We must remember that the most extreme voices are often the loudest, and that the majority of adults share similar values and concerns.”

Stress in America™ 2024: A Nation in Political Turmoil reveals a country where trust has been shaken in the government and in each other. Most adults (54%) reported they have very little to no trust in the U.S. government, and 41% of adults reported the state of the nation has made them consider moving to a different country. Half of adults (50%) said tension around social and political topics makes them less likely to want to connect with other people and around 3 in 10 (28%) said they have nothing in common with people who have different political opinions than they do. More than 2 in 5 adults (46%) wouldn’t date someone who didn’t share the same political opinions (47% of women said this, and 45% of men).

Yet the survey showed commonalities regardless of political party affiliation, with the future of the nation being the stressor that was most commonly rated as significant by Republicans (80%), Democrats (79%) and independents (73%). Further, Republicans, Democrats and independents agreed that the country’s system of checks and balances isn’t working (76% of Republicans, 71% of Democrats and 74% of independents). They also reported being stressed that politicians aren’t talking about the things that are most important to them (62%, 58% and 60%, respectively), and that the political climate has caused strain between them and their family members (32%, 35% and 32%, respectively).

Mis- and disinformation have dialed up the volume on stress, as many adults (73%) reported it is stressful to know how real fake information can look or seem. A strong majority (82%) of U.S. adults were worried that people may be basing their values and opinions on false or inaccurate information.

Despite the pervasive stress about the nation’s future and the fear of violence, this year’s survey showcased how participants are using the political climate as a springboard for activism and driving positive change. More than three-quarters of adults (77%) said they intend to vote in the presidential election, and half of adults (51%) said they feel more compelled to volunteer or support causes they value — significantly higher than the 45% who said so in 2019 during the lead up to the 2020 presidential election. Diverse communities in particular are being moved to act; 73% of Black adults and 67% of Latino/a/e adults reported feeling that their vote matters.

In addition, 3 in 5 adults reported feeling hopeful about the change this election will bring (61%), and that this election will lead to a more inclusive society (59%). More than 2 in 5 adults (42%) said they haven’t felt this excited about an election in years. Significantly, although Black and Latino/a/e groups and those who identify as LGBTQ reported personal safety as a major stressor (47%, 47% and 50%, respectively), they have remained optimistic; 64% of Black and Latino/a/e adults reported feeling hopeful that the election could mean a more inclusive future.

“Stress surrounding the upcoming election seems overwhelming. But despite concerns about a nation divided across cultural identities and political parties, it’s encouraging that hope could be the catalyst, where people can come together and have a stake in deciding their future,” said Evans. “We see people’s desire for positive change as an opportunity to channel our collective stress into meaningful conversations and actions that promote healing and understanding.”

For more information on the survey findings and helpful resources on how to handle stress, go to www.stressinamerica.org.

METHODOLOGY
The 2024 Stress in America™ survey was conducted online within the United States by The Harris Poll on behalf of the American Psychological Association between Aug. 1–23, 2024, among 3,305 adults ages 18+ who reside in the U.S. that serves as a nationally representative sample. In addition to the national sample, oversamples were collected to allow for subgroup analysis within race/ethnicity groups. Sample sizes across the national and oversamples are as follows: 801 Black, 855 Hispanic and 804 Asian. Interviews were conducted in English and Spanish. Throughout the report, mentions of political parties are defined by those who self-identify as registered voters of the Democratic, Republican, or independent party. A full methodology is available.

The American Psychological Association, in Washington, D.C., is the largest scientific and professional organization representing psychology in the United States. APA’s membership includes over 157,000 researchers, educators, clinicians, consultants and students. Through its divisions in 54 subfields of psychology and affiliations with 60 state, territorial and Canadian provincial associations, APA works to advance the creation, communication and application of psychological knowledge to benefit society and improve people’s lives.

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SOURCE American Psychological Association

Technology

SINBON Is Expanding Possibilities Across Industries at Electronica 2024

Published

52 mins ago

October 22, 2024

Brand’s technological innovation and broad capabilities are making ideas into reality across Europe’s key sectors

MUNICH and TAIPEI, Oct. 22, 2024 /PRNewswire/ — SINBON, a Taiwan-based electronic interconnect design and integration service provider, is unveiling its latest solutions to be showcased at the upcoming Electronica 2024 trade show. The lineup illustrates how the brand’s robust technological innovation and broad customization capabilities are expanding possibilities for Europe’s most critical industries.

Please join SINBON at Hall A2, Booth 241 at Electronica 2024: Messe München, Nov. 12 – 15, 2024

For visitors to experience firsthand, SINBON will have over 60 products for various industries on display, including several solutions new to Electronica this year:

Industrial IoT: Hybrid SPE connectors—the topic of a SINBON webinar to be broadcast live at the booth—and customized solutions for smart factories, robotics, and warehouse systemsGreen energy: Customized solutions for solar energy infrastructureElectric vehicle and e-mobility: NACS AC/DC charging cables; swappable batteries; customized connectors; CCS1 and CCS2 DC charging cables and inlets; connectors tailored to e-scooters and e-motorcycles; and system integration for e-bikesMedical: Solutions for patient monitoring equipment and surgical instruments; and the Electrical Muscle Stimulation (EMS) Impulse Pack with Arm Straps

Transforming the impossible to the possible across industries: VIRALIETY

SINBON’s theme for Electronica this year will be “VIRALIETY: Unreal to Real”— coined by combining the limitless possibilities of “virtual reality” with “variety.” The theme reflects the company’s ability to innovate to overcome challenges for customers with novel solutions, as well as its extensive capabilities and reach across industries.

“SINBON keeps some of Europe’s biggest industries linked with the latest connector technologies,” noted Barrie Ryan, President of SINBON Europe. “We’ve achieved this reach by transforming our clients’ ideas into reality. Often a solution doesn’t exist yet, and we have the capabilities to turn the impossible into the possible across a wide variety of sectors.”

Exploring how hybrid SPE accelerates industrial IoT

Hybrid single pair ethernet (SPE) delivers greater power and data transmission speeds while minimizing cables in industrial spaces. To explore this new connectivity technology, SINBON’s booth will feature a live broadcast of the company’s webinar Elevating Industrial Connectivity: Hybrid Single Pair Ethernet on Thursday, November 14, 2024, 10:30AM Central European Summer Time (UTC +02:00).

Webinar details and registration: https://us02web.zoom.us/webinar/register/WN_B2c6tSpSQw24W4-kBO6Hyg#/registration

Interactive, hands-on experiences at Electronica 2024

Offering a new and memorable way to interact with SINBON experts, visitors to the booth will have the chance to play a game that involves finding the SINBON guru using Augmented Reality. Participants will be able to win a unique gift from the company.

Booth visitors will also have the chance to test SINBON’s solutions for themselves. For industrial and automotive industries, the company is making its charging cables for robots and EVs available for attendees to experience how quickly and seamlessly they charge. In addition, visitors can also try out the new EMS Arm Straps. Lastly, SINBON will share numerous product stories that explore how they came to life and how they solve customer pain points.

About SINBON Electronics

Established in 1989 in Taiwan, SINBON Electronics is a leading provider of integrated design and production services for bespoke interconnect solutions. Driven by a commitment to customer centricity and the principles of ESG, the company offers a wide range of products and OEM/ODM services that ensure reliability and efficiency, combining extensive engineering expertise, industry knowledge, and leading innovations to customize solutions for long-term customer success. SINBON has a global footprint, with operations in Taiwan, China, Japan, the United Kingdom, Germany, Hungary, and the United States.

To learn more about SINBON’s services, please visit www.sinbon.com or follow on LinkedIn.

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Technology

Ariceum Therapeutics Presents Outstanding Data on its First-in-Class Radiopharmaceutical Drug 225Ac-Satoreotide at the European Association of Nuclear Medicine 2024

Published

53 mins ago

October 22, 2024

225Ac-Satoreotide is a first-in-class somatostatin receptor 2 antagonist targeting extensive stage small cell lung cancer and is the first antagonist labelled with 225Ac to enter clinical developmentSatoreotide expressed a superior pharmacokinetic profile relative to DOTA-TATE with a higher pre-clinical anti-tumour efficacy, irrespective of radionuclide used100% survival with a single dose of 30 kBq 225Ac-satoreotide but not with 225Ac-DOTA-TATE

BERLIN, Oct. 22, 2024 /PRNewswire/ — Ariceum Therapeutics (Ariceum), a private biotech company developing radiopharmaceutical products for the diagnosis and treatment of certain hard-to-treat cancers, today announces that it presented data on its proprietary radiolabelled peptide SS0110 (satoreotide), a first-in-class antagonist of the somatostatin receptor 2 (SSTR2), at this year’s European Association of Nuclear Medicine (EANM) Annual Conference, held in Hamburg, Germany from 19-23 October 2024.

The Top-Rated Oral Presentation (TROP) entitled ‘225Ac-SSO110 induces long-lasting anti-tumour responses in contrast to 225Ac-DOTA-TATE and 161Tb-DOTA-TATE in the treatment of SSTR2-positive tumour xenografts’, details the anti-tumour efficacy of different radiolabelled satoreotide antagonists (225Ac, 161Tb, 177Lu-labelled SSO110) versus respective DOTA-TATE agonists (225Ac- and 161Tb-labelled DOTA-TATE) in mice engrafted with SSTR2 positive xenografts of small cell lung cancer (SCLC) and pancreatic cancer using clinically relevant associated dose ranges.

Results demonstrate that 225Ac-satoreotide shows the strongest anti-tumoural effect in vivo at a low single dose when evaluating satoreotide and DOTA-TATE radiolabelled with different radionuclides. Irrespective of the radionuclides used, satoreotide demonstrated a higher pre-clinical anti-tumour efficacy when compared to DOTA-TATE which was less potent and required increased dose levels. Satoreotide was well tolerated across all dose levels and with all used radionuclides. These comparisons between satoreotide and DOTA-TATE will facilitate and guide further clinical development of satoreotide across multiple indications expressing SSTR2, such as SCLC, pancreatic cancers and Merkel Cell Carcinoma (MCC).

Previous comparisons between satoreotide and DOTA-TATE demonstrated that antagonist, 225Ac-satoreotide, is multiple times more potent than SSTR2 agonist, 225Ac-DOTA-TATE, signifying a durable complete response in standard murine xenograft models of SCLC in animal models, versus tumour growth delay.

Ariceum had previously shown at the Society of Nuclear Medicine and Molecular Imaging (SNMMI) Annual Meeting 2024 that 212Pb was not seen to be more potent than Lutetium or Terbium but caused more side effects and hence was not further pursued.

Manfred Rüdiger, Chief Executive Officer at Ariceum Therapeutics, said: “These results provide strong evidence for satoreotide and its potential to clinically outperform SSTR2 targeting agonists, by demonstrating significantly better efficacy in tumour growth control, up to complete tumour eradication depending on isotope used. In addition, when a single dose of 30 kBq 225Ac-satoreotide was administered, we observed high frequency of complete durable responses and 100% survival which strongly supports further clinical development for the treatment of SCLC, MCC and other cancers.”

Details of the oral presentation are as follow:

Title: 225Ac-SSO110 induces long-lasting anti-tumour responses in contrast to 225Ac-DOTA-TATE and 161Tb-DOTA-TATE in the treatment of SSTR2-positive tumour xenografts

Presenting Author: Prachi Desai, Scientist at Ariceum Therapeutics

Session Number: 1204
Session Title: M2M Track – TROP Session: Radiopharmaceutical Sciences + Translational Molecular Imaging & Therapy Committee: From Radionuclide to Clinical Translation

Oral Presentation Date & Time: Tuesday 22 October 2024, 09:00 AM – 09:10 AM CEST

Abstract Authors: Prachi Desai, Manuel Sturzbecher
– Hoehne,
Dennis Mewis, Manfred Ruediger & Anika Jaekel of Ariceum Therapeutics

Abstracts are available in the September edition of Springer’s European Journal of Nuclear Medicine and Molecular Imaging (EJNMMI) abstract book here and on the Ariceum website here.

About Ariceum Therapeutics

Ariceum Therapeutics (Ariceum) is a private, clinical stage radiopharmaceutical company focused on the diagnosis and precision treatment of certain neuroendocrine and other aggressive, hard-to-treat cancers. The name Ariceum is an anagram of ‘Marie Curie’ whose discovery of radium and polonium have been huge contributions to finding treatments for cancer.

Ariceum’s lead targeted systemic radiopharmaceutical product, 177Lu-satoreotide tetraxetan (“Satoreotide”), is an antagonist of the somatostatin type 2 (SSTR2) receptor which is overexpressed in neuroendocrine tumours (NETs) and some aggressive cancers such as small cell lung cancer (SCLC), or Merkel Cell Carcinoma (MCC), all of which have few treatment options and poor prognosis. Satoreotide is being developed as a ‘theranostic’ pair for the combined diagnosis and targeted radionuclide treatment of these tumours. Ariceum is also developing a radiolabelled PARP-inhibitor (ATT001), currently in Phase 1 clinical development under the trial name CITADEL-123. ATT001 was part of the acquisition of Theragnostics Ltd which was closed in June 2023.

Ariceum Therapeutics, launched in 2021, acquired all rights to Satoreotide from Ipsen. Ipsen remains a shareholder in the Company. Ariceum is headquartered in Berlin, with operations in Germany, Switzerland, Australia, United Kingdom and United States of America and with activities currently across the globe.

Ariceum is led by a highly experienced management team and supported by specialist investors including EQT Life Sciences (formerly LSP), HealthCap, Pureos Bioventures, Andera Partners and Earlybird Venture Capital. For further information, please visit www.ariceum-therapeutics.com.

About European Association of Nuclear Medicine (EANM)

The European Association of Nuclear Medicine (EANM) is a non-profit organization that promotes nuclear medicine and aims to improve public health. The EANM’s mission is to advance nuclear medicine through personalized healthcare, innovation in diagnosis and treatment, and raising awareness of nuclear medicine

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Technology

Kotak811 Launches ‘Scam The Scammers’ Playlist to Empower Customers

Published

53 mins ago

October 22, 2024

MUMBAI, India, Oct. 22, 2024 /PRNewswire/ — Kotak811 announced the launch of its new YouTube playlist, ‘Scam The Scammers’. This innovative initiative aims to equip customers with the knowledge and tools to protect themselves from financial fraud.

With the surge in digital transactions, financial scams have become increasingly sophisticated. Recognising the need to empower customers, Kotak811 has curated this playlist to serve as a comprehensive resource. The videos cover a wide range of topics, including phishing attacks, fake call scams, and unauthorised transactions, offering viewers a clear understanding of how these scams operate and how to avoid falling victim.

Learn how to scam the scammer

For a deeper understanding of how to stay away from online frauds, explore the dedicated playlist ‘Scam The Scammers’ on YouTube. From detailed explanations to practical tips, these videos offer valuable insights into the safety measures in place.

Watch now: https://www.youtube.com/watch?v=xZreQiJole8&list=PL_M0wBiHI2EMh6X4LfGyXsydBe1wv_nvm&index=4

About Kotak 811

When 8th November 2016 changed the way India transacted forever, Kotak811 was conceptualized to simplify banking and make it fully accessible online. Kotak811 was launched on 29th March 2017. As one of India’s first full service, truly digital bank, it offers customers a simple and convenient way to open a savings account and transact digitally using 180+ features on its Kotak811 Mobile Banking app, from home or on the move.

On 29th March 2022, Kotak811 presented itself as a bank within a bank, adopting a fresh and new brand identity with ‘digital at its core. As a brand ethos, Kotak811 continuously inquires into India’s banking challenges, innovates to bridge these gaps, and inspires Indians to adopt a way of banking that lets them take full control.

Kotak811 has customers from 1,000+ Cities & Towns covering over 10,000 pin codes, across the country. Every 5 seconds, a new Account is opened digitally. Interestingly, more than 50% of 811 Accounts are opened outside banking hours. Kotak 811 offers instant account opening in 3 mins and KYC via video call in 5 mins.

For more information, please visit the digital bank’s website at https://www.kotak811.com/zero-balance-savings-account-online/

Download the Kotak811 mobile banking app now:

● For Android users: Mobile Banking App

● For iOS users: Kotak811 Mobile Banking App

Disclaimer: This Article is for information purpose only

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