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AusperBio to Present Ongoing AHB-137 Clinical Data in Late-Breaking Oral Presentation at AASLD 2024

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SAN FRANCISCO, Oct. 17, 2024 /PRNewswire/ — AusperBio Therapeutic, Inc. and Ausper Biopharma Co., Ltd. (together AusperBio), a clinical-stage biotechnology company, today announced that new clinical data from its lead candidate AHB-137, an antisense oligonucleotide (ASO) therapeutic, will be featured in a late-breaking oral presentation at the 2024 Liver Meeting®, organized by the American Association for the Study of Liver Diseases (AASLD). The conference will take place from November 15-19, 2024, in San Diego, California.

AHB-137 is being developed to achieve a functional cure for chronic hepatitis B. This presentation will showcase key findings from the ongoing clinical trials, highlighting its potential to impact patient outcomes.

Oral presentation details are as follows:

Title: HBsAg loss and seroconversion in HBeAg-negative chronic hepatitis B subjects on NA therapy after AHB-137 treatment: preliminary data from an ongoing multicenter, randomized, open-label phase IIa study

Session: Late Breaking Abstract Parallel Session 2

Session Time: November 18, 2024, 5:00pm – 6:30pm PDT

Presentation Time: November 18, 2024, 6:00 pm – 6:15 pm PDT

Authors: Yanhua Ding, Xian Yu, Xieer Liang, Hong Ren, Chongyuan Xu, Wen Wang,

                Zhihong Liu, Yi Yang, Hong Zhang, Jinlin Hou, Shan Zhong, Hong Chen,

                Yilei Wen, Tingting Lu, Xiao Qiu, Lidan Wang, Di Zhao, Chen Yang, Miao

                Wang, Chris Yang, Guofeng Cheng, Junqi Niu

About AHB-137

AHB-137, a novel unconjugated antisense oligonucleotide (ASO) developed within AusperBio’s proprietary Med-Oligo™ ASO technology platform, was designed to treat chronic hepatitis B for a functional cure. Its compelling preclinical and Phase 1 clinical data was highlighted at the 2023 EASL™ conference and the 2024 EASL™ conference, respectively. This novel dual-mechanism ASO is presently undergoing a Phase 1b trial across multiple international study sites and a concurrent Phase 2 trial in China. Through a global development strategy, AHB-137 is advancing rapidly towards the goal of HBV cure.

About AusperBio.

AusperBio is a clinical-stage biopharmaceutical company with operations in the USA and China, dedicated to advancing oligonucleotide and targeted delivery technologies for transformative therapies, with an initial focus on curing chronic hepatitis B infection. The company has developed a proprietary Med-Oligo™ ASO platform which has been shown to substantially enhance the current ASO therapeutics, through novel insights into ASO design. Combining with efficient targeted delivery conjugation technologies, the modular Med-Oligo™ Platform empowers ASO therapeutics to treat a broad range of diseases, including viral infections, metabolic conditions, genetic disorders, and immune diseases. For more information, visit www.ausperbio.com

Media Contact
Email: info@ausperbio.com

Investor Contact
Tel: 650-888-1756 (US)
Email: growth@ausperbio.com

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SOURCE AusperBio Therapeutics Inc.

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HevenDrones Partners with SMARTSHOOTER for Drone Defense

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New partnership addresses mission-critical demand for counter-drone technology amid escalating global conflicts

MIAMI, Jan. 15, 2025 /PRNewswire/ — HevenDrones (Heven), the market leader in hydrogen-powered drones, announced today a partnership with SMARTSHOOTER, a global innovator in fire control systems that significantly increase hit probability against static and moving ground and aerial targets.

The collaboration integrates SMARTSHOOTER’s SMASH Dragon platform with Heven’s H100 and Urban drone platforms, enabling precision targeting and engagement of both ground and aerial threats.

“As drone conflicts escalate, we know that counter-drone technology will prove critical to the evolving needs of the armed forces,” said Bentzion Levinson, CEO of Heven. “By integrating our drones with SMARTSHOOTER’s fire control systems, we aim to address customer demand for the future needs of remotely-controlled warfare.”

SMASH Dragon is an advanced robotic weapon payload that can be mounted on various drones and unmanned aerial platforms. Leveraging SMARTSHOOTER’s SMASH proprietary fire control and target acquisition algorithms, along with ballistic-calculated shot release, the system directs the weapon and accurately times the shot to achieve a precise hit. The system is uniquely designed to lock, track, and engage unknown targets in unpredictable environments, whether static or dynamic, day or night, unaffected by target movements or human errors such as fatigue and stress.

Staying at the forefront of military technology innovation, SMASH’s proven track record includes recent successful deployments and significant contracts to supply the SMASH 3000 system to NATO Countries for counter-drone operations and equipping the British Army with SMASH systems for counter-unmanned aerial system (C-UAS) capabilities.

About HevenDrones

HevenDrones was founded in 2019 with a clear vision: To unlock the immense potential of the drone economy. Heven’s hydrogen-powered, runway-independent drones are designed with endurance and adaptability in mind. Built for the most complex missions, Heven’s drones operate anywhere—efficiently, quietly, and reliably— providing the warfighter with the technology to get the job done.

About SMARTSHOOTER

Founded in 2011, SMARTSHOOTER is an Israeli-based company that has developed world-leading fire control systems to enhance the accuracy and effectiveness of small arms. Their SMASH product line, which includes the SMASH Dragon, utilizes artificial intelligence, computer vision, and advanced algorithms to enable precise targeting of both ground and aerial threats, including drones. Headquartered in Yagur, Israel, SMARTSHOOTER also operates subsidiaries in the U.S. (Maryland), Europe (Germany), and Australia, serving a diverse array of global clients such as the Israel Defense Forces, U.S. Army, British Army, and other NATO member forces.

View original content:https://www.prnewswire.com/news-releases/hevendrones-partners-with-smartshooter-for-drone-defense-302352140.html

SOURCE Heven Drones

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HevenDrones Partners with SMARTSHOOTER for Drone Defense

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New partnership addresses mission-critical demand for counter-drone technology amid escalating global conflicts

MIAMI, Jan. 15, 2025 /PRNewswire/ — HevenDrones (Heven), the market leader in hydrogen-powered drones, announced today a partnership with SMARTSHOOTER, a global innovator in fire control systems that significantly increase hit probability against static and moving ground and aerial targets.

The collaboration integrates SMARTSHOOTER’s SMASH Dragon platform with Heven’s H100 and Urban drone platforms, enabling precision targeting and engagement of both ground and aerial threats.

“As drone conflicts escalate, we know that counter-drone technology will prove critical to the evolving needs of the armed forces,” said Bentzion Levinson, CEO of Heven. “By integrating our drones with SMARTSHOOTER’s fire control systems, we aim to address customer demand for the future needs of remotely-controlled warfare.”

SMASH Dragon is an advanced robotic weapon payload that can be mounted on various drones and unmanned aerial platforms. Leveraging SMARTSHOOTER’s SMASH proprietary fire control and target acquisition algorithms, along with ballistic-calculated shot release, the system directs the weapon and accurately times the shot to achieve a precise hit. The system is uniquely designed to lock, track, and engage unknown targets in unpredictable environments, whether static or dynamic, day or night, unaffected by target movements or human errors such as fatigue and stress.

Staying at the forefront of military technology innovation, SMASH’s proven track record includes recent successful deployments and significant contracts to supply the SMASH 3000 system to NATO Countries for counter-drone operations and equipping the British Army with SMASH systems for counter-unmanned aerial system (C-UAS) capabilities.

About HevenDrones

HevenDrones was founded in 2019 with a clear vision: To unlock the immense potential of the drone economy. Heven’s hydrogen-powered, runway-independent drones are designed with endurance and adaptability in mind. Built for the most complex missions, Heven’s drones operate anywhere—efficiently, quietly, and reliably— providing the warfighter with the technology to get the job done.

About SMARTSHOOTER

Founded in 2011, SMARTSHOOTER is an Israeli-based company that has developed world-leading fire control systems to enhance the accuracy and effectiveness of small arms. Their SMASH product line, which includes the SMASH Dragon, utilizes artificial intelligence, computer vision, and advanced algorithms to enable precise targeting of both ground and aerial threats, including drones. Headquartered in Yagur, Israel, SMARTSHOOTER also operates subsidiaries in the U.S. (Maryland), Europe (Germany), and Australia, serving a diverse array of global clients such as the Israel Defense Forces, U.S. Army, British Army, and other NATO member forces.

View original content:https://www.prnewswire.com/news-releases/hevendrones-partners-with-smartshooter-for-drone-defense-302352140.html

SOURCE Heven Drones

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Extinguishing Wildfires with Light at Meta Photonix

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SAN FRANCISCO, Jan. 15, 2025 /PRNewswire/ — MetaPhotonix Inc. (MPI), a Silicon Valley startup, is developing a revolutionary method to extinguish large-scale wildfires using nothing but light – eliminating water! The innovative technology also aims to significantly reduce the need for aircraft, and firefighters, enabling fires to be extinguished by AI remotely at the speed of light.

In 2024, MPI achieved a small yet groundbreaking milestone, by remotely extinguishing a tiny flame, equivalent to the size of a candle, using only light. While small in scale compared to actual wildfires, this experiment serves as a vital proof-of-concept, paving the way for a future where wildfires can be managed quickly and cost-effectively.

“It’s like the first transistor—early stage, but with transformative potential,” said CEO, Dr. Leo DiDomenico, a former NASA Jet Propulsion Laboratory scientist.

MPI’s technology, known as photopyrokinesis, leverages “structured light” from lasers and millimeter-wave sources. These initially low-intensity beams traverse the atmosphere where they would get focused to high-intensity at the disaster area to suppress wildfires without water, chemicals, or close-range human intervention.

This innovation could save the U.S. up to $1 trillion annually in wildfire-related costs, an amount rivaling the nation’s military budget, while addressing up to 20% of global CO₂ emissions.

Using precise light beams, MPI’s technology can potentially even target fires near buildings, offering a critical tool for protecting lives and property. Therefore, this approach is a potential game-changer for the insurance industry, allowing them to keep insuring homes, by reducing claims from wildfires. Each community might someday have its own quick-acting AI fire sentry protecting lives and homes – making fire insurance viable again.

Photopyrokinesis works by directing beams of structured light to fire zones to manipulate the electronic structure of the atmosphere and create localized shockwaves that deny oxygen to the fire. This process provides millions of tiny, controlled explosions each second, extinguishing flames rapidly and efficiently. It is like using dynamite to put out an oil well fire, but much more controlled and targeted.

The structured light’s unique properties allow it to even propagate on curved trajectories, like water from a hose, enabling precise targeting of the fire even in extreme wind conditions like Santa Ana winds.

Founded in 2022 by Dr. DiDomenico, MetaPhotonix Inc. is advancing in the XPRIZE Wildfire competition, but needs visionary investors to help scale this technology and protect lives, ecosystems, and economies from the devastating effects of wildfires.

 

View original content to download multimedia:https://www.prnewswire.com/news-releases/extinguishing-wildfires-with-light-at-meta-photonix-302351269.html

SOURCE MetaPhotonix Inc

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