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LenioBio Collaborates with ReciBioPharm to Scale Up ALiCE® Technology and Expedite Vaccine Production

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Advancing CEPI’s 100 Days Mission to Accelerate Vaccine Development

DUSSELDORF, Germany, Oct. 2, 2024 /PRNewswire/ — LenioBio, the leader in rapid cell-free protein expression technologies, is pleased to announce a collaboration with ReciBioPharm, a global contract development and manufacturing organization (CDMO), to scale up protein manufacturing capabilities and expedite vaccine production.

This collaboration is part of the expansion in scope of LenioBio’s CEPI-funded project, which aims to showcase the capacity and speed of LenioBio’s proprietary ALiCE® protein expression technology to accelerate production of vaccine-relevant proteins for use in clinical trials. This project fully aligns with the 100 Days Mission spearheaded by CEPI.

The project extension follows a successful first six months during which LenioBio achieved all key milestones. They successfully demonstrated  ALiCE®’s ability to reliably produce vaccine-relevant proteins at small scales from cell-free DNA formats, and developed a suite of novel quality control assays to ensure the highest standards of product integrity and safety throughout the protein production process.

Building on this success, LenioBio will be collaborating with ReciBioPharm to achieve scaled production of vaccine proteins using ALiCE®. ReciBioPharm’s expertise in process development and manufacturing of complex biologics, along with its global footprint, will be instrumental in unlocking the full potential of ALiCE® for vaccine manufacturing and pave the path towards future GMP applications.

“Being involved in the 100 Days Mission is both an honor and a significant responsibility,” said André Goerke, CEO of LenioBio. “Our collaboration with ReciBioPharm brings us one step closer to making the vision of rapid vaccine development a reality. By transferring protein production with ALiCE® to a leading CDMO, we aim to meet the urgent need for swift vaccine production, crucial for containing emerging health threats.”

The newly announced collaboration will include technology transfer for 10-liter scale protein production of a vaccine candidate, using ALiCE®- including both upstream and downstream unit operations – to ReciBiopharm’ site in Oeiras, Portugal. This process will involve initial process and analytical method transfer and will deliver material to be used in pre-clinical studies. Establishing the ALiCE® technology in a scaled manufacturing environment is a critical first step in a roadmap toward GMP and the production of material for clinical trials and vaccine manufacture.

Vikas Gupta, president, ReciBioPharm, said: “Our collaboration with LenioBio represents a significant step forward in recombinant protein manufacturing. LenioBio’s ALiCE® technology is well-positioned to make a meaningful impact on global health, and accelerate the development of vaccines and other critical biologics. ReciBioPharm is glad to play a crucial role in proving LenioBio’s innovative platform at-scale and look forward a future where such technology will be used in clinical trials. This partnership perfectly aligns with our commitment to innovation. We are making the vision of a future where vaccines can be developed and deployed more rapidly in response to emerging threats, a reality.”

Looking ahead, LenioBio plans to conduct in-depth evaluations of ALiCE®-produced protein quality through in vivo studies focusing on dosage and efficacy. The company also intends to engage in further regulatory discussions to position ALiCE® as a platform technology for expedited development of protein medicines, aiming to reduce the time it takes for vaccines and therapeutics to reach clinical trials.

The 100 Days Mission:

The 100 Days Mission, spearheaded by CEPI and embraced by global leaders in the G7 and G20, seeks to dramatically shorten the vaccine development timeline. By reducing the time it took to develop the first licensed COVID-19 vaccines by two-thirds, this initiative has the potential to prevent future epidemics from escalating into pandemics.

About LenioBio

LenioBio is a life sciences biotech company, pioneering a disruptive protein expression platform. Using ALiCE® technology, enabling customers – researchers and biopharma manufacturers to streamline and accelerate their protein discovery, development, and production processes. LenioBio simplifies manufacturing and speeds up the delivery of drugs to the patients.

About ReciBioPharm

ReciBioPharm, a division of Recipharm, is a contract development and manufacturing organization (CDMO) specifically established to focus on serving companies seeking to develop and commercialize advanced therapy medicinal products (ATMPs). ReciBioPharm’s specialized CDMO capabilities include pre-clinical to clinical and commercial development and manufacture for new biological modalities encompassing technologies based on live viruses and viral vectors, live-microbial biopharmaceutical products, nucleic acid-based mRNA and plasmid DNA production. Led by a management team and technical experts with a proven track record in both process development and contract manufacturing, ReciBioPharm offers the knowledge and resources necessary to help customers develop and manufacture promising new therapies to meet the needs of patients across the world.

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Government of Canada leverages new technologies to improve HR and pay operations and support employees

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GATINEAU, QC, Oct. 2, 2024 /CNW/ – The Government of Canada is committed to supporting employees and resolving outstanding pay issues for federal public servants while working to improve their overall human resources (HR) and pay experience. Pay issues that employees continue to face are unacceptable and it is our top priority to resolve them.

Today, the second quarterly progress report was published, which provides an update on ongoing progress related to HR and pay. This summer, we have been working on various projects to better support employees, while also improving current operations and continuing to explore a new HR and pay solution. The report includes details on:

Pay Centre virtual assistant;MyGCPay improvements;Dayforce user awareness sessions;New Case Client Relationship Management tool

In 2021, we began exploring and testing the Dayforce solution, a viable option for the next modern HR and pay system. This fall, we started the Dayforce user sessions to provide public servants with an opportunity to try Dayforce and provide their feedback.

To help resolve pay issues and improve our operations, we launched various HR and pay initiatives, such as a new artificial intelligence (AI) based virtual assistant to support compensation advisors and significantly reduce processing times. We are also in the early stage of exploring options for a new and modern Case Client Relationship Management tool, which will allow for more efficient management of pay transactions.

The Government of Canada will continue engaging with employees and stakeholders while working on various initiatives to support its employees, resolve HR and pay issues, and make progress on exploring a possible replacement for Phoenix. Quarterly updates on the progress of HR and pay projects will also be provided.

Quote

“We are improving our current operations to better serve federal public servants, while working towards a new HR and pay system that meets our needs now and into the future.  It is our responsibility to ensure public servants are paid accurately and on time.”

The Honourable Jean-Yves Duclos
Minister of Public Services and Procurement and Quebec Lieutenant

“All public service employees deserve to be paid accurately and on time. As we work on improvements to our systems by reducing the number of HR systems in the core public administration and facilitating automation, we will work closely with bargaining agents to simplify overall human resources processes for employees, managers and pay practitioners.”

The Honourable Anita Anand
President of the Treasury Board and Minister of Transport

Quick facts

$135 million was allocated in Budget 2024 to explore a new HR and pay solution for 2024-25, $112.1 million is allocated to PSPC and $22.7 million is allocated to TBS. The total includes an allocation of $85 million to amend the contract with Dayforce to continue to expand testing and design the system to our specific needs.The current HR and pay systems are used to deliver pay to over 430,000 current and former public servants from over 100 departments and agencies. In 2023, this represented approximately 13.1 million payments, totalling approximately $36 billion.So far in 2024, we’ve achieved an enterprise-wide average biweekly payroll accuracy of 97.8%The Public Service Pay Centre provides pay services for 49 organizations serving over 250,000 clients.As part of Budget 2024, the Government of Canada allocated an additional $135 million to expand testing and design of a new HR and pay solution for the public service. This decision supports the eventual replacement of the Phoenix pay system and its HR systems.

Associated links

Summer 2024 Quarterly progress report 

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SOURCE Public Services and Procurement Canada

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Institutional Investor Launches the First Global Think Tank for the Asset Management Industry

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NEW YORK, Oct. 2, 2024 /PRNewswire/ — After over two decades of leading peer-to-peer learning and networking, Institutional Investor (II) is proud to announce the launch of the Asset Management Institute (AMI) — the first global think tank and private C-suite network designed exclusively for the asset management industry. The launch coincides with the release of II’s inaugural Global Asset Management Survey.

“This is part of II’s strategic vision to partner holistically with clients across every function,” said Kat Storfer, Head of North America at Institutional Investor. “We are proud to be the only organization capable of delivering value to asset management firms through an exclusive, prestigious C-suite network on a global scale.”

With the current wave of change affecting the sector — from leadership transitions to advancements in technology and AI — now is the ideal moment for the industry to have a dedicated private platform for sharing insights, benchmarking, and discussing its future.

The Institute will have dedicated sub-networks tailored for key C-suite roles, including CEOs, CIOs, CFOs, COOs, CHROs, General Counsel, Chief Compliance Officers, Chief Marketing Officers, Chief Technology Officers, Chief Product Officers, and Heads of Distribution. This structure underscores the growing strategic importance of these leadership positions within asset management firms and their influence at the board level. And with its global reach, AMI is uniquely positioned to align with the international scope of the asset management community and the broader financial industry.

Jim McCaughan, Chairman of the Asset Management Institute, added: “AMI members are at the forefront of the industry, constantly driving innovation and learning from one another. The Institute will amplify knowledge and create meaningful connections as investment management undergoes a time of tremendous transformation.”

Membership in the Asset Management Institute is by invitation only. For more information about AMI, please visit https://eml.iiconferences.com/l/81142/2024-07-23/667g4x/81142/1727702061ureg3lPn/AMI_Overview___Oct24.pdf or contact David Braham, +1 (212) 224-3212, david.braham@institutionalinvestor.com.

Contact: Bryan Fox
Marketing Director
bryan.fox@institutionalinvestor.com

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SOURCE Institutional Investor

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G2 Customer Reviews Name Appdome Leader in Five New Categories

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Appdome wins ‘Anti-Fraud,’ ‘Mobile Data Protection,’ ‘Best Meets Requirements,’ ‘Easiest Setup’ and ‘Easiest to Do Business With’ Among Other Recognition

SAN FRANCISCO, Oct. 2, 2024 /PRNewswire/ — Appdome, the experience leader in mobile defense, today revealed it has been recognized as the market leader and high performer in five (5) additional categories on G2, the world’s largest and most trusted software marketplace. The five (5) new leadership categories include Anti-Fraud, Mobile Data Protection, Meets Requirements, Easiest Setup and, as a company, Easiest to do Business With. This extends Appdome’s experience leadership, adding to its prior customer recognition as Most Likely to Recommend and Users Love Us.

“Our customers trust Appdome to provide always-on, continuous defense for their mobile business,” said Jamie Bertasi, Chief Customer Officer of Appdome. “Appdome isn’t a point product. This customer recognition spans the full range of the value proposition we provide every mobile business, in mobile app security, anti-fraud, bot defense, DevSecOps, compliance and more.”

The Appdome Platform provides full lifecycle defense for mobile brands and enterprises. It’s the only solution that can centralize mobile defense for external-consumer and internal-employee use cases into one platform and workflow, and streamline the secure, monitor and respond lifecycle for 340+ mobile defenses with ease. Appdome 340+ defenses work with all Android & iOS platforms and apps and include the widest defense selection offered by any one vendor. These defenses are offered in broad feature categories including mobile app security, anti-fraud, anti-malware, anti-cheat, anti-bot, geo compliance, social engineering, Mobile EDR, Mobile XDR, and more. To simplify deployment, maintain agility, and shorten incident response times, Appdome uses AI/ML to code the defenses into Android & iOS applications and mobile SDKs as well as to monitor and respond automatically to threats and attacks as they arise. To use Appdome, there’s no SDK, no server, no code or coding needed by an engineering team.

“The architecture and technology behind Appdome are the difference,” said Chris Roeckl, Chief Product Officer of Appdome. “While others try to add a GUI on top of their SDK-based point products, Appdome’s GUI isn’t the story. The story is the modular architecture and how we use AI/ML to code the defenses into mobile apps, adapting the defense to each application. Continuous defense is our advantage.”

Customers report robust feature coverage, high quality support, and ease of setup with rapid time to implement for fast ROI. For example, one customer in Healthcare says “Easy security with Appdome… very extensive set of security features allow us to improve security applications very fast.” While a Security Engineering Manager said “The product stands out for ease of implementation… with just a few clicks all necessary protections can be enabled.” A customer in Financial Services noted “dedicated and attentive onboarding team and customer support with fast and meaningful turnarounds on all support requests.”

“The industry is seeing a significant surge in mobile fraud and bot attacks, which in turn is causing significant financial loss and customer frustration,” said Brian Reed, SVP Marketing at Appdome, “Mobile brands and enterprises are starting to ask ‘Why spend time and resources trying to stitch together multiple point products to handle the myriad of security and fraud threats we’re facing, when we can seamlessly and efficiently deliver all the protection needed in the mobile business with a click of a button and let AI/ML do the work?’ They’re right. Appdome’s approach makes business sense.”

Learn more about what real users have to say about Appdome on G2’s review page.

For more information on the Appdome Unified Mobile App Defense Platform, visit https://www.appdome.com

About Appdome
Appdome is the experience leader in mobile defense. Our award-winning, and patented, mobile defense platform uses AI-ML to automate the work and complexity out of securing mobile businesses, apps and users. With Appdome, mobile brands and enterprises enjoy a single pane of glass to create Certified Secure™ mobile apps with ease, eliminating multiple point products and SDKs, and unifying mobile app security, anti-fraud, anti-bot, anti-malware, geo compliance, social engineering and other defenses with real time threat monitoring, mobile EDR, XDR, and IR for external-consumer and internal-employee facing mobile apps. At 340+ mobile app defense features and growing, Appdome provides the most comprehensive and extensible mobile defense solution on the market. The platform is fully automated out of the box using pre-built plugins to the full DevOps, CI/CD and Enterprise automation and support stack. Appdome also leads the market in user experience and support, with its industry leading, in-app, Threat-Events™ threat intelligence framework and GenAI powered Threat Resolution Center™. These, combined with a host of enterprise grade and compliance features built into the platform, allow all stakeholders, including mobile engineering, cyber teams, network security, DevOps, SecOps, IT, UEM-MAM, mobile support teams, and mobile end users to benefit from using Appdome. Appdome holds several patents including U.S. Patents 9,934,017 B2, 10,310,870 B2, 10,606,582 B2, 11,243,748 B2 and 11,294,663 B2. Additional patents pending. 

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SOURCE Appdome

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