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Vanderbilt University School of Medicine Basic Sciences Adds Carterra’s LSAXT Instrument to Speed Drug and Vaccine Research and Advance Patient Care

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The Center for Structural Biology in the School of Medicine Basic Sciences will be a hub of research innovation using Carterra’s platform in traditional and AI-driven workflows for characterizing both antibodies and other biomolecules

SALT LAKE CITY and NASHVILLE, Tenn. , Sept. 25, 2024 /PRNewswire/ — Carterra® Inc., the world leader in innovative technologies enabling high-throughput biology, and the Vanderbilt University School of Medicine Basic Sciences announced today the addition of the Carterra LSAXT label-free interaction analysis platform to the Center for Structural Biology (CSB). Vanderbilt and Vanderbilt University Medical Center researchers will be able to discover and characterize large molecules including antibodies.

“Many of our researchers are trying to identify antibodies that bind to a protein involved in health or disease,” said Borden Lacy, director of the CSB and Edward and Nancy Fody Chair in Pathology and professor of biochemistry and pathology, microbiology and immunology. “The ability to rapidly screen and quantify binding for large libraries of antibodies will shape the way molecular discovery moves forward at Vanderbilt. The work we spend months on will now be completed in a matter of days. It is incredibly exciting.” 

Carterra’s LSA platform was used by pharmaceutical giant Eli Lilly during the COVID-19 pandemic to find antibodies effective against SARS-CoV-2. Within 90 days of isolating antibodies from an early COVID-19 survivor, Lilly was in clinical trials with the world’s first COVID-19 therapeutic, the antibody Bamlanivimab.

BAM, as it became known, is the fastest drug ever discovered and saved countless lives.  The publication in Science describing the feat concluded, “The resulting speed at which this drug discovery and development effort progressed…is a testament to the advanced discovery and characterization platforms.”

Vanderbilt investigators will now be able to leverage the Carterra platform for a variety of research aims. 

Two projects that are getting early traction include:

Stephanie Wankwicz, assistant professor of molecular physiology and biophysics and a faculty affiliate of the Center for Applied AI in Protein Dynamics, is elucidating the role of entropy in substrate specificity and catalysis.  Wankowicz is planning to use Carterra’s platform to more quickly and efficiently analyze a large panel of peptide sequence variants against a kinase. Older methods are very low throughput and would require high concentrations of the protein/peptide solution.

Brian Wadzinski, associate professor of pharmacology, recently submitted a grant application to characterize pan- and phosphor-specific nanobodies for investigating MAPK and PP2A signalling. Affinity measurements for these large panels of nanobodies and high-resolution epitope binning can only be performed on Carterra’s platform.

The LSAXT instrument includes hardware and software features that build upon the capabilities of Carterra’s original and highly successful LSA instrument while maintaining its impressive throughput and sample efficiency. The LSA platform delivers 100 times the data in 10 percent of the time-to-answer and uses only 1 percent of the sample required by other label-free platforms.

Just last year, Vanderbilt launched the Center for Applied AI in Protein Dynamics which will also benefit from the addition of Carterra’s platform.  The LSA® is the only label-free biosensor that can generate enough data, quickly and efficiently, to train algorithms and learning models used to predict the affinity and epitope coverage of drug candidates. Pharmaceutical and biotech companies who have now moved to AI-driven drug discovery workflows have standardized on the LSA.

Vanderbilt has always led its peers in research innovation,” commented Tim Germann, Chief Commercial Officer at Carterra. “To enable the use of AI in antibody discovery and characterization by adding the LSAXT to its stable of technologies cements Vanderbilt’s position as the academic leader in this rapidly evolving research landscape.”

Since its launch in 2018, Carterra’s interaction analysis platform has penetrated 19 of the largest 20 pharmaceutical companies, major universities and vaccine makers, contract research organizations (CROs), and biotechs on four continents. Characterizing binding kinetics and epitope coverage of large numbers of antibodies in early research has been transformative. The LSA platform has been profiled in multiple Science, Nature, and Cell peer-reviewed papers.

Media Contact:
Cheri Salazar, Sr. Marketing Manager
Carterra, Inc.
(408) 594-9400
Csalazar@carterra-bio.com 

About Carterra, Inc.
Carterra® is privately held and is the leading provider of high-throughput technologies designed to accelerate and improve the discovery of novel therapeutic candidates. Carterra’s LSA® instrument, software, and consumables for biotherapeutic discovery and characterization deliver up to 100 times the throughput of existing platforms in 10% of the time while using only 1% of the sample required by other systems. The LSA combines patented microfluidics technology with real-time high-throughput Surface Plasmon Resonance (HT-SPR) and industry-leading data analysis and visualization software to revolutionize mAb screening. The new LSAXT provides enhanced optics to enable additional applications in biotherapeutic discovery and characterization. Carterra, Inc. is based in Salt Lake City, Utah, and has Customer Experience Centers in San Francisco, Salt Lake City, Boston, Manchester, England, and Munich, Germany. Carterra products are available in Asia-Pacific and Oceania through our exclusive distributor, Revvity. For additional information, please visit www.carterra-bio.com.

About the Vanderbilt Center for Structural Biology
The Vanderbilt Center for Structural Biology promotes the broad use of structural biology approaches in all life science research and provides resources for education and training in state-of-the-art technologies. Uniquely, the CSB merges applications of high resolution structural biology disciplines, X-ray crystallography, NMR spectroscopy, cryo-electron microscopy and computational biology, with the biophysical instrumentation needed to characterize biomolecular interactions. This strategy allows researchers to solve fundamental structural problems in medicine and biology. The CSB facilitates collaborations with investigators across a range of Departments in both the College of Arts and Science, the School of Medicine Basic Sciences, and the School of Medicine in Vanderbilt University Medical Center. The CSB is directed by Borden Lacy, Edward and Nancy Fody Chair in Pathology and professor of biochemistry and pathology, microbiology and immunology.

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Rad Power Bikes Expands Its Omnichannel Retail Experience to Include BestBuy.com and Select Best Buy Stores

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Additional physical and digital channels provide Rad Power Bikes customers more ways to interact with the brand and access Rad’s latest ebike models.

SEATTLE, Sept. 25, 2024 /PRNewswire/ — Rad Power Bikes™ today announced its teaming up with Best Buy to increase the brand’s retail presence to include 150 Best Buy stores nationwide and BestBuy.com. After several product launches, this availability enhances the seamless integration of Rad’s retail channels, enriching the customer journey from online to in-store. This expansion of Rad’s omnichannel experience underscores the company’s dedication to creating a world where transportation is not only energy-efficient and accessible but also enjoyable for everyone, no matter where they shop or how they engage with the brand.

Rad Power Bikes Expands Its Omnichannel Retail Experience to Include BestBuy.com and Select Best Buy Stores

As Rad continues to redefine sustainable transportation, the expansion to Best Buy will provide more customers with direct access to Rad’s industry-leading products in physical retail locations and online. Starting today, customers can purchase some of our rider’s favorite Rad products and accessories at BestBuy.com, and next month in 150 Best Buy stores nationwide.

“Rad Power Bikes is strategically positioning itself for sustained growth by focusing on safety, reliability, and customer accessibility,” said Phil Molyneux, CEO of Rad Power Bikes. “Our commitment to strengthening our product offerings and broadening our retail experiences for customers ensures more people can experience the benefits of ebikes. As we continue to innovate and grow beyond our direct-to-consumer roots, we remain dedicated to maintaining the highest standards of safety, quality, and customer satisfaction, which have been key in building our strong reputation with customers and retailers large and small.”

Rad is also expanding its retail partner program and is pleased to announce the appointment of industry veteran George Lee as Director of Sales. This key addition will further strengthen and grow the company’s retail partnerships, enhancing the overall customer experience and accelerating growth.

Rad Power Bikes is also planning exciting Black Friday deals on its versatile ebikes to offer even more customers the opportunity to experience the freedom and convenience of Rad Power Bikes at a great value.

Rad Power Bikes offers test rides and in-store support at its RadRetail locations, ensuring that customers can find the right ebike for their needs, whether commuting, adventuring, delivery, or hauling kids. For more information on how Rad Power Bikes is making ebikes more accessible, and to locate a store near you, visit here.

About Rad Power Bikes
Rad Power Bikes boasts a full lineup of affordable ebikes and accessories that are changing the way people and products ride for good. Founded in 2007, Rad’s team of passionate ebike enthusiasts creates products and service solutions that are purpose-built for everything, whether for commuting, adventuring, delivery, or hauling kids. The ebikes and accessories are all designed in-house at its Seattle headquarters. The company serves riders across the U.S. and Canada, and has nine RadRetail locations, and more than 1,200 retail and service partners across North America.Recognized by TIME, Fast Company, and Inc. as one of the most innovative and influential companies, Rad Power Bikes is on a mission to build a world where transportation is energy-efficient, enjoyable, and accessible to all.

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SOURCE Rad Power Bikes

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Admitad’s new generation promo code solution boosts conversion for affiliates by 40%

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DUBAI, UAE, Sept. 25, 2024 /PRNewswire/ — Admitad, a global leader in partner marketing, launches New Generation Promo codes — a turnkey solution that offers a hassle-free way to attribute sales directly to affiliates through promo codes. Publishers receive full credit for every sale generated, regardless of how or where the transaction occurs. Brands enjoy increased tracking transparency and accuracy, wider reach and boosted sales. The loyalty of publishers to advertisers is also growing due to increased profits at the same traffic volumes.

By assigning a dedicated code to each affiliate, the solution ensures personalised promotions that increase the relevance and impact of marketing campaigns, while for publishers it guarantees no risk of promo code theft or cookie stuffing. Through access to a broader network, including social media influencers and content creators, businesses can expand their reach, diversify traffic sources, and unlock new audience segments.

Solution embraces the CPS model, guaranteeing that businesses only pay for completed sales. This makes marketing spend more predictable, enabling companies to optimise their ROI. Promo codes are automatically withdrawn from publishers failing to generate sales within a specified timeline and are then reallocated to those who consistently deliver results.

Promo code tracking also solves the problem of cross-device order attribution, including tracking on mobile devices and within mobile applications. Admitad’s solution is able to bypass other tracking obstacles as well. It works seamlessly even if ad blockers, privacy settings and other extensions interfere with traditional cookie tracking.

Affiliates using New Generation Promo codes alongside their affiliate links have experienced a significant spike in conversions. Admitad compared the number of actions and growth rate of partners who previously worked only with affiliate links. Calculations showed consistent 30-40% growth in the number of actions and sales after just 3 months of promo code usage.

More conversions translate directly into increased commissions and revenue growth. By offering discounts or special offers, they incentivize consumers to make purchases that might not have otherwise been considered. It also offers publishers a powerful tool to foster deeper customer engagement.

Publishers and brands can access New Generation Promo codes through the Promo code Catalog in the Admitad Store. These codes are recommended to be used alongside the affiliate links, offering a powerful combination that ensures the best possible tracking and maximizes the conversion potential.

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SOURCE Admitad

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Swan Bitcoin Has Achieved SOC2 Type 1 Compliance

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The independent audit and certification affirms that Swan’s platform, infrastructure, tools, and processes meet industry best practices to protect sensitive client information. 

CALABASAS, Calif., Sept. 25, 2024 /PRNewswire/ — Swan Bitcoin is proud to announce that it has successfully achieved SOC 2 Type 1 compliance, marking a significant milestone in its dedication to ensuring the highest standards of security, availability, and confidentiality for its customers. This certification, awarded by Schellman, a high-ranking IT compliance attestation firm, details the suitability of design and operating effectiveness of controls relevant to security, availability, and confidentiality to protect sensitive data.

“Every day, we handle mission-critical information,” said Yan Pritzker, Swan CTO. “This requires Swan to implement thorough security and risk controls across our whole domain, including network security, systems availability, and data confidentiality. With a SOC2-compliant environment, we are assuring our customers and partners that we can meet their stringent compliance requirements.”

SOC 2 reports are performed in accordance with the Statement on Standards for Attestation Engagements 18 (SSAE 18) attestation standard issued by the American Institute of Certified Public Accountants (AICPA). Achieving SOC 2 Type 1 certification demonstrates that Swan meets industry best practices to assure clients that their data is being handled with the utmost care and protection.

“At Swan, security is a top priority,” said Scott Kisser, Swan CISO. “Achieving SOC 2 compliance underscores our commitment to building trust by adhering to industry-leading security practices. This independent verification is another step in our continued journey to provide the most secure and trusted Bitcoin platform for our clients.”

SOC 2 compliance brings critical benefits such as reduced risk, enhanced client trust, and the confidence that Swan Bitcoin is continuously improving its security posture. The completion of Swan’s SOC 2 Type 1 report is the result of an independent audit conducted to ensure the proper design and effectiveness of a variety of controls. For more information, please visit trust.swanbitcoin.com.

About Swan

Swan is a leading Bitcoin financial services company with more than 130,000 clients. Established in 2019, Swan helps individuals and institutions to understand and invest in Bitcoin. The Swan app simplifies Bitcoin purchases with instant and recurring buys. Swan IRA provides a tax-advantaged solution for saving Bitcoin in retirement accounts. For HNWIs and businesses, Swan Private provides white-glove service for large purchases, treasury solutions, and inheritance planning. With Swan Vault, clients can easily custody their own Bitcoin with peace of mind. Swan Managed Mining provides clients with fully segregated and dedicated mining operations, catering to their unique requirements, opportunities, and strategic advantages. Swan prides itself on exceptional client service, making Bitcoin approachable to all. For more information, please visit swan.com.

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SOURCE Swan Bitcoin

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