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Flagship Pioneering Unveils Abiologics to Pioneer Supranatural Biologics, A New Biotherapeutic Class

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The Abiologics platform leverages cutting-edge generative AI and high throughput chemical protein synthesis to create Synteins™, a new class of programmable medicines that aims to redefine what therapeutics can achieve for patients

The company emerges after 3 years of platform development and an initial commitment of $50 million from Flagship Pioneering

CAMBRIDGE, Mass., July 23, 2024 /PRNewswire/ — Flagship Pioneering, the bioplatform innovation company, today unveiled Abiologics, a company reimagining biologics with the creation of a new class of supranatural and programmable medicines, called Synteins™. Synteins are computationally-generated and synthesized with novel building blocks, endowing them with extraordinary properties to bring life-changing treatments to patients across a wide range of diseases. Flagship has initially committed $50 million to advance the company’s platform and develop a diverse pipeline of medicines, with an initial focus on oncology and immunology indications.

“Biologics have transformed medicine in the past forty years, but only a fraction of their potential has been realized because we’ve been limited by the boundaries of nature,” said Noubar Afeyan, Ph.D., Founder and CEO of Flagship Pioneering and Co-Founder and Chairman of the Strategic Oversight Board of Abiologics. “With the convergence of advancements in generative artificial intelligence, automated polymer synthesis and chemical functionalization coupled with a vision to develop more powerful medicines with unprecedented diversity, we asked, what if we could design biologics entirely from new building blocks that could overcome the most critical limitations of today’s medicines?”

The Abiologics platform is a fully integrated digital and automated wet-lab infrastructure to create supranatural biologics with powerful, desirable pharmacological properties. The platform leverages state-of-the-art generative artificial intelligence (AI) to computationally-design Synteins de novo using a broad set of artificial building blocks, far beyond the 20 naturally occurring amino acids that form the basis of today’s biologic medicines. These include biologics built with D-amino acids, chemically identical mirror images of standard amino acids. Once designed, Abiologics chemically synthesizes its digitally-optimized Synteins with pioneering new technologies. As a result, Synteins can be programmed to interact with virtually any therapeutic target while evading the body’s natural defenses. By surpassing the limitations of traditional biologics discovery tools, Abiologics is the first to discover, prototype and scale-up polymers composed solely of artificial building blocks, and to date has successfully generated Synteins made entirely of D-amino acids that bind a diversity of therapeutically relevant targets while remaining ultrastable.

“For the first time, we are able to imagine and generate chemically synthesized biologics at scale and with increasing programmability, offering a new class of medicines with transformative potential,” said Avak Kahvejian, Ph.D., Co-Founder and CEO of Abiologics and General Partner at Flagship Pioneering. “Creating protein biologics with artificial building blocks rather than naturally occurring amino acids allows Synteins to go unrecognized by the immune system, offering significant advantages compared to today’s biologics such as less frequent dosing, oral delivery and the ability to reach parts of the body that were previously impossible to access and treat. With Synteins, Abiologics is poised to bring boundary-breaking medicines to patients across a range of diseases.”

In addition to Afeyan and Kahvejian, Abiologics’ founding team includes Mike Hamill, Ph.D., Chief Innovation Officer of Abiologics and Senior Principal at Flagship Pioneering, Kala Subramanian, Ph.D., Founding President of Abiologics and Operating Partner at Flagship Pioneering, Jaclyn Dunphy, Ph.D., Senior Director of Strategy and Research Operations at Abiologics, and Alicia Kaestli, Ph.D., Senior Associate at Flagship Pioneering. Bradley Pentelute, Ph.D., Professor of Chemistry at MIT, is an Academic Co-Founder of Abiologics.

About Abiologics
Abiologics is pioneering a new class of supranatural and programmable biologics, called Synteins™. The Abiologics platform leverages cutting-edge generative artificial intelligence and high-throughput chemical protein synthesis to create Synteins with powerful, desirable pharmacological properties, redefining what therapeutics can achieve for patients across a range of disease areas. Abiologics was founded by Flagship Pioneering in 2021. For more information, visit us at www.abiologics.com and follow us on LinkedIn and X/Twitter.

About Flagship Pioneering
Flagship Pioneering invents and builds bioplatform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in more than $75 billion in aggregate value. To date, Flagship has deployed over $3.8 billion in capital toward the founding and growth of its pioneering companies alongside more than $27 billion of follow-on investments from other institutions. The current Flagship ecosystem comprises 40 companies, including Foghorn Therapeutics (NASDAQ: FHTX), Moderna (NASDAQ: MRNA), Sana Biotechnology (NASDAQ: SANA), Generate BiomedicinesInariIndigo Agriculture, and Tessera Therapeutics.

Media Contact:
press@flagshippioneering.com

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SOURCE Flagship Pioneering

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TELUS Acquires Additional Shares of TELUS Digital

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VANCOUVER, BC, Sept. 27, 2024 /PRNewswire/ – TELUS Corporation (“TELUS”) today announced that it has acquired, through a wholly owned subsidiary, an aggregate of 2,593,631 subordinate voting shares (the “Purchased Shares”) in the capital of TELUS International (Cda) Inc. (“TELUS Digital”) by way of market purchases over the facilities of the Toronto Stock Exchange. As a result of the acquisition of these subordinate voting shares, TELUS has acquired an additional 2.35% interest in the TELUS Digital subordinate voting shares since TELUS’ prior early warning report filed on August 16, 2024. When added to the 4,031,191 subordinate voting shares held prior to the last report, TELUS now holds approximately 5.99% of the outstanding subordinate voting shares.

“We continue to hold confidence in TELUS Digital and its long term profitable growth strategy,” said Darren Entwistle, President and CEO of TELUS. “In recognition of the considerable opportunities ahead, we are once again increasing our existing share ownership of the subordinate voting shares in the public market. These purchases are not part of a strategy to privatize the business, but rather, a reflection of our strong belief in the meaningful and sustainable value that TELUS Digital will create for stakeholders in the years to come.”

The purchase of the Purchased Shares is being made pursuant to the normal course purchase exemption set forth in section 4.1 of National Instrument 62-104.

Before giving effect to the purchase subsequent to our August 15th news release, TELUS held an aggregate of 152,004,019 multiple voting shares of TELUS Digital and 4,031,191 subordinate voting shares. These securities represented approximately 92.5% of the outstanding multiple voting shares and 86.9% of the outstanding voting rights attached to all shares of TELUS Digital and approximately 56.8% of the total shares outstanding, reflecting the conversion by Riel B.V. of multiple voting shares into subordinate voting shares. The 2,593,631 Purchased Shares were acquired at an average purchase price of C$4.90, representing a total additional investment, before trading commissions, of C$12,703,197. After giving effect to the market purchases, TELUS holds an aggregate of 152,004,019 multiple voting shares and 6,624,822 subordinate voting shares. The shares held by TELUS now represent approximately 92.5% of the outstanding multiple voting shares, 6.0% of the outstanding subordinate voting shares, 57.7% of the outstanding shares of TELUS Digital and 87.0% of the outstanding voting rights of TELUS Digital. The multiple voting shares of TELUS Digital may be converted into subordinate voting shares on a one-for-one basis at any time.

TELUS purchased the Purchased Shares for investment purposes and may or may not purchase or sell multiple voting shares, subordinate voting shares or other securities of TELUS Digital in the future on the open market or in private transactions, depending on market conditions and other factors. TELUS currently has no other plans or intentions that relate to its investment in TELUS Digital. Depending on market conditions, general economic and industry conditions, TELUS Digital’s business and financial condition and/or other relevant factors, TELUS may at any time develop other plans or intentions in the future relating to one or more of the above items. A copy of the early warning report to be filed by TELUS in connection with the acquisition will be available on TELUS Digital’s profile on SEDAR+ at sedarplus.ca. Alternatively, you may contact TELUS Investor Relations at 1-800-667-4871 in order to obtain a copy of the report.

The headquarters and principal executive offices of TELUS Digital are located at Floor 5, 510 West Georgia Street, Vancouver, British Columbia, Canada V6B 0M3

About TELUS

TELUS (TSX: T, NYSE: TU) is a dynamic, world-leading communications technology company with more than $20 billion in annual revenue and over 19 million customer connections spanning wireless, data, IP, voice, television, entertainment, video, and security. Our social purpose is to leverage our global-leading technology and compassion to drive social change and enable remarkable human outcomes. Our longstanding commitment to putting our customers first fuels every aspect of our business, making us a distinct leader in customer service excellence and loyalty. The numerous, sustained accolades TELUS has earned over the years from independent, industry-leading network insight firms showcase the strength and speed of TELUS’ global-leading networks, reinforcing our commitment to provide Canadians with access to superior technology that connects us to the people, resources and information that make our lives better.

Operating in 32 countries around the world, TELUS Digital Experience (TSX and NYSE: TIXT) is a leading digital customer experience innovator that designs, builds, and delivers next-generation solutions, including AI and content moderation, for global and disruptive brands across strategic industry verticals, including tech and games, communications and media, eCommerce and fintech, banking, financial services and insurance, healthcare, and others.

TELUS Health is a global healthcare leader, which provides employee and family primary and preventive healthcare and wellbeing solutions. Our TELUS team, along with our 100,000 health professionals, are leveraging the combination of TELUS’ strong digital and data analytics capabilities with our unsurpassed client service to dramatically improve remedial, preventive and mental health outcomes covering over 75 million lives, and growing, around the world. As the largest provider of digital solutions and digital insights of its kind, TELUS Agriculture & Consumer Goods enables efficient and sustainable production from seed to store, helping improve the safety and quality of food and other goods in a way that is traceable to end consumers.

Driven by our determination and vision to connect all citizens for good, our deeply meaningful and enduring philosophy to give where we live has inspired TELUS and our team to contribute $1.7 billion, including 2.2 million days of service since 2000. This unprecedented generosity and unparalleled volunteerism have made TELUS the most giving company in the world. Together, let’s make the future friendly.

For more information about TELUS, please visit telus.com, follow us at @TELUSNews on X and @Darren_Entwistle on Instagram.

Investor Relations
Robert Mitchell
(647) 837-1606
ir@telus.com

Ian McMillan
(604) 317-8768
ir@telus.com 

Media Relations
Steve Beisswanger
(514) 865-2787
Steve.Beisswanger@telus.com

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SOURCE TELUS Corporation

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Observo AI, the AI-Powered Telemetry Data Pipeline, Joins the Azure Marketplace

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Observo AI, the AI-powered security and observability telemetry pipeline is now available on Azure Marketplace.

FREMONT, Calif., Sept. 27, 2024 /PRNewswire-PRWeb/ — Observo AI, a pioneer in creating security and observability data pipelines powered by Artificial Intelligence, today announced a partnership with Microsoft and the availability of Observo on Azure Marketplace. This will make it easier for Azure customers to quickly adopt Observo to help control costs, manage data sprawl, boost productivity, and identify and resolve critical incidents faster.

There is huge growth in data sent to analytics platforms by security teams. Costs for MS Sentinel are increasing at an untenable pace. Azure customers now have access to Observo AI through Azure Marketplace to optimize this data, route it to Sentinel, and save as much as 50% on SIEM costs.

Customers can now deploy Observo AI at speed while benefiting from Azure’s trusted and secure infrastructure, as well as its global commercial footprint. Availability on the Azure Marketplace will enable seamless purchasing and invoicing, with customers able to use their existing Microsoft Azure Consumption Commitment (MACC) to purchase Observo AI.

“Many of our customers who have moved to Azure are experiencing a huge increase in telemetry data sent to analytics platforms by Security and DevOps teams. Expenditures on tools like Microsoft Sentinel are increasing at an untenable pace,” said Ricky Arora, Co-Founder and COO of Observo AI. “Azure Cloud customers now have access to Observo AI through the Azure Marketplace to optimize this data, route it to Sentinel or any other analytics tool, and save as much as 50% on security costs.”

“Observo AI, available on the Azure Marketplace, offers a solution for Microsoft Azure and Sentinel customers struggling with the relentless growth of security data,” said Jatinder Mann, CEO of Cetark, a cyber security services company specializing in Microsoft Security portfolio. “Observo AI empowers Security teams to optimize costs, speed incident response, and ensure robust security and compliance with a seamless, fast, and easy purchase option through the Azure Marketplace.”

Learn More

For more details on how Azure customers can take advantage of Observo AI’s AI-powered pipelines, read the complete announcement on the Observo AI blog. Visit the Observo AI Website at www.observo.ai Watch the Observo AI explainer video at https://vimeo.com/899662669

About Observo AI

Observo AI was created to help solve the biggest telemetry data problems. Observo helps reduce security costs by 50% or more while resolving incidents more than 40% faster. Our AI-Powered Observability Pipeline helps break-free from static, rules-based pipelines. Observo automates security and observability with a pipeline that constantly learns and improves. Minimize risks, enhance visibility, protect sensitive data, and stay in compliance with Observo AI.

Media Contact

Bryan Turriff, Observo AI, 1 5014129978, bryan@observo.ai, www.observo.ai

View original content to download multimedia:https://www.prweb.com/releases/observo-ai-the-ai-powered-telemetry-data-pipeline-joins-the-azure-marketplace-302260671.html

SOURCE Observo AI

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VXI Global Solutions to grow Morrow, GA location with up to 300 new positions to support new clients

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VXI Global Solutions announced today an expansion of their customer service center at 1000 Southlake Circle, adding over 300 new full-time positions to support multiple new clients.

MORROW, Ga., Sept. 27, 2024 /PRNewswire-PRWeb/ — VXI Global Solutions, a leading provider of customer experience (CX) and business process outsourcing (BPO) solutions, announced today an expansion of their customer service center at 1000 Southlake Circle, adding over 300 new full-time positions to support multiple new clients.

“We have an amazing group of people at VXI,” said Tommy Thompson, Director of Operations for VXI Morrow. “I am delighted to be able to bring meaningful job opportunities to this community. Over 85% of our leaders are promoted internally, so there are real opportunities for career growth.”

The state-of-the-art facility offers full-time positions where high performers can earn $40,000 per year with impressive weekly incentives depending on the client program they support. VXI is looking for applicants with experience in Customer Service, Sales, and Tax Preparation all with start dates throughout October and November 2024.

Local Head of Talent Acquisition, Chelsea Yancoskie, shared, “We are excited to welcome our new clients and offer these on-site positions to the local community, providing opportunities to share in our success. We’re not only looking for customer service professionals but also individuals with significant experience in sales and income tax preparation. Starting wages begin at $17 per hour, with some positions offering up to $19 per hour depending on the candidate’s qualifications.”

VXI provides paid training, comprehensive medical, dental, and vision benefits, 401(k) options, paid time off, and one of the industry’s best unlimited employee referral programs. VXI Morrow is located in Southlake Mall, so employees can easily access the Food Court and retail shops just steps away, offering convenience during breaks and before or after shifts. Team members are encouraged to “Stand Out & Fit In” by participating in the Visionaries & Passion4 volunteer programs focused on promoting an inclusive workplace and community support events. Additional perks include discounted cell phone plans, rewards programs, and frequent prize giveaways and free luncheons.

“We have an amazing group of people at VXI,” said Tommy Thompson, Director of Operations for VXI Morrow. “I am delighted to be able to bring meaningful job opportunities to this community. As one of the largest certified minority-owned businesses in the US, VXI was recently recognized as one of Newsweek’s Greatest Places to Work for Diversity and our culture is second to none. Over 85% of our leaders are promoted internally, so there are real opportunities for career growth.”

To learn more and apply, please visit the VXI Careers website or click the link: VXI Morrow apply

About VXI Global Solutions 

VXI Global Solutions is a BPO leader in customer service, customer experience, and digital solutions. Founded in 1998, the company has over 40,000 employees in more than 40 locations in North America, Asia, Europe, and the Caribbean. VXI delivers omnichannel and multilingual support, software development, quality assurance, and CX advisory, automation, and process excellence to the world’s most respected brands.

VXI is backed by private equity investor Bain Capital and is one of the fastest growing, privately held business services organizations in the United States and the Philippines, and one of the few U.S.-based customer care organizations in China.

For more information, visit http://www.vxi.com.

Media Contact

VXI Corporate Communications, VXI Global Solutions, (213) 637-1300, comms@vxi.com, https://vxi.com/

View original content:https://www.prweb.com/releases/vxi-global-solutions-to-grow-morrow-ga-location-with-up-to-300-new-positions-to-support-new-clients-302261560.html

SOURCE VXI Global Solutions

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