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Gattaca Genomics Launches Landmark Study to Revolutionize Embryo Selection in IVF

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Gattaca Genomics has received approval for a landmark study to combine timelapse imaging and genetic testing to enhance embryo selection in IVF. Partnering with IVF clinics worldwide, the study aims to identify key developmental patterns that predict healthy embryos, potentially improving IVF success rates.

FT. LAUDERDALE, Fla., May 31, 2024 /PRNewswire-PRWeb/ — Gattaca Genomics, a pioneer in genetic diagnostics and reproductive technologies, is proud to announce Institutional Review Board (IRB) approval for its multi-center study, “Embryo Assessment Utilizing Timelapse Imaging in Conjunction With Preimplantation Genetic Testing for Aneuploidy With Next Generation Sequencing.” This groundbreaking study will examine the relationship between embryo development and aneuploidy, a condition where embryos have an abnormal number of chromosomes.

The study is currently recruiting IVF centers interested in participating, by collaborating with clinics worldwide, Gattaca Genomics aims to collect a large and diverse dataset that will provide valuable insights into the complex relationship between embryo development and aneuploidy.

“This study could be a game-changer for hopeful parents struggling with infertility,” said Dr. Mari said Dr. Mari Mitrani, Chief Science Officer and co-founder at Gattaca Genomics.

“By harnessing the power of time-lapse imaging and genetic testing, we aim to give experts the tools they need to identify the strongest embryos, potentially making IVF more successful.”

“Aneuploidy is a major obstacle for many couples pursuing IVF, and we believe this study has the potential to unlock new insights into how we can better identify and select embryos with the greatest chance of resulting in a healthy pregnancy,” said Dr. Eva Schenkman, Director of Embryology Services at Gattaca Genomics.

Understanding and Assessing Aneuploidy

Aneuploidy is a genetic condition where cells have an abnormal number of chromosomes. In humans, cells typically have 46 chromosomes arranged in pairs. Aneuploidy occurs when cells have either an extra chromosome (trisomy) or a missing chromosome (monosomy). This can lead to various genetic disorders, including Down syndrome (trisomy 21).

In the context of IVF and embryo selection, aneuploidy is a significant concern as it can impact the viability of embryos and increase the risk of miscarriage. Identifying and selecting embryos without aneuploidy is crucial in improving IVF success rates.

Timelapse imaging, a technology that allows embryologists to assess embryo development in real-time, has been available for nearly a decade. However, previous studies have been limited by small sample sizes or have failed to establish a definitive correlation between timelapse data and genetic outcomes. Gattaca Genomics aims to address these limitations by leveraging its extensive network of partner clinics to collect data from multiple sites, creating a robust dataset that combines timelapse imaging with next-generation sequencing.

“This study represents a truly collaborative effort, uniting IVF clinics in the pursuit of scientific discovery and improved patient care,” said Dr. Tyl Taylor, Director of Genetic Services at Gattaca Genomics. “By pooling our resources and expertise, we can unlock valuable insights that will ultimately benefit countless families on their journey to parenthood.”

The study is currently recruiting IVF clinics that are interested in participating. Participating clinics will receive a timelapse incubator to facilitate data collection. By collaborating with clinics across the country, Gattaca Genomics aims to collect a large and diverse dataset that will provide valuable insights into the complex relationship between embryo development and aneuploidy.

More information about the study design can be found at ClinicalTrials.gov

About Gattaca Genomics

Gattaca Genomics is a trailblazer in reproductive health, offering cutting-edge genetic testing to empower individuals and couples in their family planning journey. Our expertise in Preimplantation Genetic Testing (PGT) and Whole Genome Sequencing (WGS) provides crucial insights to inform meaningful decisions. Led by CEO Michael Carbonara and Chief Scientific Officer Dr. Maria Ines “Mari” Mitrani, our team combines visionary leadership with scientific rigor to deliver personalized support and a deep understanding of each family’s unique needs. By harnessing the power of advanced technology, Gattaca Genomics is transforming family planning, offering sophisticated solutions that enhance the chances of a healthy pregnancy while minimizing genetic risks.

For further information, please contact:

Press:

Marley Peters

Gattaca Genomics PR

marley@dontbealittlepitch.com

Trial participation:

Tyl Taylor

Director of Genetic Services

trials@gattacagenomics.com

https://gattacagenomics.com/

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SOURCE Gattaca Genomics

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Earth’s pulse monitored: a review highlights remote sensing time series progress

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As urbanization accelerates and environmental dynamics shift, the need for accurate and timely terrestrial monitoring has never been more urgent. A review has introduced a novel approach to remote sensing time series analysis, integrating multi-source data to enable near real-time monitoring. This innovative methodology promises to transform environmental conservation and urban planning by providing unprecedented insights into terrestrial changes and offering a more precise understanding of environmental dynamics.

GUANGZHOU, China, Dec. 22, 2024 /PRNewswire-PRWeb/ — An international team of researchers from South China Normal University, the University of Connecticut, and the Chinese Academy of Sciences has made a significant breakthrough in remote sensing. Their review, published (DOI: 10.34133/remotesensing.0285) in the Journal of Remote Sensing on December 11, 2024, addresses key challenges in remote sensing, such as incomplete data and noise interference. The team’s new time series analysis technique leverages advanced data reconstruction and fusion methods, significantly enhancing the precision and efficiency of remote sensing for monitoring environmental changes.

The research team has developed an advanced time series analysis technique that combines deep learning algorithms with traditional remote sensing methods to integrate data from various remote sensing sources. This innovative approach allows for the extraction of subtle patterns from large, complex datasets, which is crucial for monitoring critical environmental parameters such as land use and vegetation health. Unlike conventional techniques that struggle with incomplete or noisy data, this new methodology offers enhanced accuracy and more reliable insights into terrestrial dynamics, paving the way for more effective environmental monitoring.

Central to the study’s success is the integration of Long Short-Term Memory (LSTM) networks and Generative Adversarial Networks (GANs) to address the challenges posed by missing or noisy data. The LSTM networks capture temporal trends over time, while the GANs generate synthetic data that mimics real-world observations to fill gaps and correct for atmospheric distortions. This dual approach has resulted in a cleaner, more accurate time series dataset, which was validated against independent ground truth measurements. The researchers demonstrated significant improvements in key vegetation indices, such as the Normalized Difference Vegetation Index (NDVI), setting a new benchmark in the field of remote sensing.

Experts in the field have lauded the study’s potential to revolutionize remote sensing applications. They see the method as a transformative tool for enhancing high-resolution monitoring and extending its coverage, particularly in agricultural surveillance, urban planning, and environmental management. “This method represents a crucial advancement in our ability to monitor environmental changes,” says Professor Fu. “As it evolves, it could play a key role in addressing climate change and other global challenges.”

The methodology’s future applications are vast, especially in global environmental monitoring and supporting sustainable development goals. By integrating multi-temporal data from Landsat and Sentinel-2 satellites, the team has created a framework for accurate and continuous terrestrial analysis. As computational power advances and algorithms improve, this technology is expected to become a vital tool for natural resource management, disaster response, and climate change mitigation. In the years to come, it could provide critical data to help policymakers address pressing environmental issues on a global scale.

References

DOI

10.34133/remotesensing.0285

Oiginal Source URL

https://doi.org/10.34133/remotesensing.0285

Funding information

This work was supported by the National Nature Science Foundation of China (grant numbers 42425001 and 42071399).

About Journal of Remote Sensing

The Journal of Remote Sensing, an online-only Open Access journal published in association with AIR-CAS, promotes the theory, science, and technology of remote sensing, as well as interdisciplinary research within earth and information science.

Media Contact

George Hua, Chuanlink Innovations, 1 8656606278, TranSpread1@gmail.com, http://chuanlink-innovations.com/

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ZINZINO AB (PUBL.): ENTERS INTO AGREEMENT TO PROVIDE DIP FINANCING TO ZURVITA INITIATING CHAPTER 11 PROCESS

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GOTHENBURG, Sweden, Dec. 22, 2024 /PRNewswire/ — Zinzino has in a press release dated 20240617 announced that a letter of intent to acquire 100% of the shares in the North American direct selling company Zurvita Inc. “Zurvita or the Company” was signed. Since then, Zinzino has negotiated with the owners of Zurvita Inc. and instead concluded that the purchase of Zurvita’s assets in a Chapter 11 proceeding for the Company is in Zinzino’s best interest.

Zinzino is providing a debtor-in-possession (DIP) financing to Zurvita, which filed for Chapter 11 bankruptcy proceedings on the 20th December 2024. By entering as a financier in Zurvita’s Chapter 11 with loans totaling USD 4.5 million, Zinzino simultaneously makes an offer to acquire the company’s assets via a so-called stalking horse bid. If the bid is accepted, the DIP loan will be converted into part of a debt-settled purchase price, which will be determined after Zurvita has completed the sale process that is subject to higher and better offers in accordance with the applicable terms of Chapter 11. Other bidders have the right to submit bids for Zurvita during the process and if another bid is accepted, Zinzino’s loan will be repaid and certain of its costs associated with the process will be reimbursed. 

Zurvita is a direct selling health company with operations in the United States, Canada and Mexico. The brand portfolio offers a range of innovative health and wellness products. The business has total annual sales of approximately USD 30 million with good gross margins. A potential transaction with Zinzino is expected to add growth through the synergies arising from the joint networks, combined with Zinzino’s test-based product concept. The profitability of the Company will thus be able to develop well by utilizing Zinzino’s existing technical platform and organization.

A visionary mindset, tech first perspective, test-based nutrition at the cellular level and a strong position to capitalize on current trends will form the basis of the new partnership. Following the acquisitions of VMA Life in 2020, Enhanzz in 2022, the strategic partnership with ACN and the recently completed asset acquisition of Xelliss, Zinzino has been looking for further strong investments to maintain its sustainable, profitable growth, strengthen its distribution power, expand into new markets and leverage the product portfolio in new consumer areas.

– “Individualized advice and tailored solutions are the future, and not just in health and wellness,” says Dag Bergheim Pettersen, CEO of Zinzino. “Together, we have years of combined industry experience and everything it takes to drive the modern, personalized shopping experience through direct sales”. Jay Shafer, CEO and co-founder of Zurvita, states “After considering multiple options for the company and under the guidance of our attorneys and third-party advisors, we feel this presents the best opportunity to continue Zurvita’s mission, deliver the highest quality products, and provide continuity for our staff and consultants. We are excited to see what the future holds for Zurvita.” 

For more information:
Dag Bergheim Pettersen CEO Zinzino +47 (0) 932 25 700, www.zinzino.com

Pictures for publication free of charge:
marketing@zinzino.com

Certified Adviser:
Carnegie Investment Bank AB (publ.)

Zinzino AB (publ.) is obliged to publish this information in compliance with current EU regulations governing market abuse. The information was provided by the above contact person for publication at 20.00 on the 21st of December 2024.

This information was brought to you by Cision http://news.cision.com

https://news.cision.com/zinzino/r/zinzino-ab–publ–enters-into-agreement-to-provide-dip-financing-to-zurvita-initiating-chapter-11-pr,c4086040

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Meet With Culture: Exquisite Craftsmanship of Traditional Chinese Architecture

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BEIJING, Dec. 22, 2024 /PRNewswire/ — The Temple of Agriculture in Beijing played a significant role during the Ming (1368-1644) and Qing (1644-1911) dynasties. Over nearly 600 years, 25 emperors personally visited or sent ministers to perform spring farming ceremonies and offer sacrifices to Shennong, the god of agriculture.

 

Built in 1420 during the Yongle reign, the temple’s predecessor was the Temple of Mountains and Rivers in Nanjing. When Emperor Zhu Di moved the Ming capital to Beijing, he constructed a larger temple inspired by the Nanjing temple, which gradually evolved into the Temple of Agriculture.

The Taisui Hall, the largest building complex in the temple, now serves as a major exhibition hall of the Beijing Ancient Architecture Museum, showcasing models of classical Chinese buildings and demonstrating the solemnity of royal architecture.

Ancient Chinese architecture is predominantly wooden-structured, chosen for its availability, versatility, and earthquake resistance. Artisans developed sophisticated techniques in material selection and construction. The wooden framework consists of columns, beams, girders, and purlins, with innovative structural forms like lifting-beam and piercing-bracket structures.

A unique architectural element is the dougong (bracket sets), which supports weight and connects beam frames with column walls. Mortise-tenon joints were invented to create elastic frameworks by connecting different components.

While discussing the Temple of Agriculture, it’s worth noting another remarkable example of architectural hierarchy which could be found in the Temple of Heaven. The hierarchy of architectural designs reflected social stratification, with eave structures like the triple-layered eaves of the Hall of Prayer for Good Harvest representing the highest-level architectural design.

Over centuries, the Temple of Agriculture has transformed from an imperial garden to a public park and a museum for historical architecture, now standing as a significant cultural landmark that symbolizes China’s agricultural civilization and architectural heritage along Beijing’s Central Axis.

Quickly join Alexandre to study and explore the traditional Chinese architecture.
https://youtu.be/YpA03WiZ9Wc

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SOURCE China International Communications Group

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