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NeoPhore appoints Michael Shih as Chief Executive Officer

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Highly experienced corporate development leader with a track record of international pharma and biotech deal-makingNew CEO to drive growth strategy to maximise the potential of drug discovery pipeline to treat cancer

LONDON, Dec. 16, 2024 /PRNewswire/ — NeoPhore Limited, a small molecule neoantigen immuno-oncology company, today announces the appointment of Michael Shih as Chief Executive Officer (CEO) and to the Board of Directors, effective immediately.

Michael Shih has nearly 20 years of experience in business development, licensing and mergers & acquisitions. Michael was most recently Vice President of Corporate Development at Kite Pharma, where he led multiple business development opportunities for the Company. Before this, Michael was Senior Vice President, Head of Business Development at Biogen, leading the team responsible for sourcing, structuring and executing strategic collaborations and merger and acquisition opportunities. Prior to joining Biogen, Michael was Vice President and Head of Global Transactions at Sanofi, where he oversaw the structuring and negotiation of business development transactions across Sanofi’s business units. Michael has also held senior business development roles at Epizyme, Forest Laboratories and Eisai. 

Robert James, Chairman of the Board, NeoPhore, said: “Michael joins at an exciting stage in NeoPhore’s development having raised a significant Series B financing round which was supported by Bristol Myers Squibb. As we move closer to being a clinical Company Michael’s experience as a corporate development leader in pharma and biotech will be instrumental in driving NeoPhore’s next phase of growth.”

Michael Shih, newly appointed Chief Executive Officer and Board of Director, NeoPhore commented: “NeoPhore’s differentiated approach to targeting the MMR pathway has huge potential to treat cancer. I am looking forward to working with the highly experienced NeoPhore team, who are all clearly aligned to advance the Company’s pipeline.”

An attorney by training, Mr. Shih previously practiced law at several New York firms and held senior legal positions in-house at Eisai Inc., specialising in licensing, corporate transactions, and litigation.

NeoPhore is developing a pipeline of highly validated, first-in-class small molecule drugs targeting proteins across the MMR pathway to improve the efficacy and durability of revolutionary immunotherapies to treat cancer. The appointment of Michael Shih as CEO follows the close of the Company’s oversubscribed Series B financing. The financing and new appointment of the CEO strengthen NeoPhore’s position to drive its growth strategy and maximise the potential of its pipeline.

About NeoPhore Ltd

NeoPhore, UK is focused on the discovery and development of novel small molecule therapies to treat cancer through stimulation of the immune system. Generation of cancer neoantigens in tumours can be exploited by the patients’ immune system to overcome natural defence mechanisms in cancer. The Company’s approach targets the DNA mismatch repair (MMR) pathway, which has been proven to promote neoantigen creation and subsequent immunity against numerous cancers. Using these insights, NeoPhore aims to generate next-generation immuno-oncology therapeutics to improve clinical outcomes for cancer patients. NeoPhore was spun-out of the University of Turin and PhoreMost Ltd by the CRT Pioneer Fund. For more information, please visit www.neophore.com

 

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CSharpCorner Announces 2025 Industry-Leading Conference Lineup to Drive Education and Innovation in Software Development

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NEW YORK, Dec. 27, 2024 /PRNewswire/ — CSharpCorner, the world’s premier developer community, is excited to announce its 2025 lineup of industry-leading conferences, addressing the growing demand for events that drive education, networking, and innovation in all areas of software development, including Web3 and AI. These conferences, attended by hundreds of thousands annually, continue to provide valuable opportunities for developers to Learn, Earn, and Grow.

CSharpCorner’s 2025 calendar offers a dynamic mix of virtual and in-person events, providing cutting-edge content, career growth opportunities, and networking with industry experts to support a thriving developer ecosystem.

2025 Conference Lineup:

March: .NET Virtual Conference. A premier event showcasing the latest advancements in .NET technologies, tools, and frameworks to help developers stay at the forefront of innovation.May: Modern Database Conference. Focused on modern database systems, this conference covers trends, solutions, and best practices for efficiently managing data.June: Code Quality Conference. Dedicated to improving software quality, the event explores techniques, tools, and methodologies to write cleaner, more efficient, and maintainable code.July: Cloud Summit. A comprehensive summit covering the major cloud platforms—Amazon Web Services, Microsoft Azure, and Google Cloud—helping developers build, scale, and deploy cloud-based solutions.August: Software Architecture Conference – A deep dive into the principles, strategies, and best practices of software architecture, empowering developers to design scalable and robust systems.October: Action AI Conference & BCrypt Conference. The Action AI Conference highlights the latest breakthroughs in Artificial Intelligence, while the BCrypt Conference focuses on Web3 technologies, blockchain, and decentralized solutions.November: Frontend Days – Angular, React, Vue, and Blazor. A must-attend event for frontend developers to explore trends, frameworks, and tools in building dynamic and engaging user interfaces.December: Growth Mindset Conference. Designed to inspire and motivate, this event focuses on personal and professional development to help developers thrive in their careers and embrace a growth mindset.

“At CSharp, our mission is to empower developers by offering platforms where they can access cutting-edge content, connect with like-minded professionals, and advance their careers,” said Mahesh Chand, founder & CEO of CSharpCorner. “Our 2025 conferences are designed to meet the evolving needs of the developer community, driving innovation in areas like Web3, AI, cloud computing, and software architecture.”

CSharpCorner plays a pivotal role in supporting developers worldwide, equipping them with the knowledge and tools they need to succeed in an ever-changing technology landscape.

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SOURCE CSharp Inc

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Nest Partners with Dinari to Deliver Real World Yield Through First Tokenized Blackstone ETF on Plume

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NEW YORK, Dec. 27, 2024 /PRNewswire/ — Nest, the flagship RWA staking protocol exclusive to Plume Network, today announced the first tokenized Blackstone ETF vault through its partnership with Dinari. Nest’s new permissionless vault features the Blackstone Senior Loan ETF, and will deliver real world yields to DeFi users once the vault is launched on Plume mainnet. This announcement marks a significant expansion of Dinari’s long-term partnership with Plume, as the established tokenization platform brings institutional-grade assets into the rapidly growing Plume ecosystem.

The first tokenized Blackstone ETF on Plume Network joins Nest’s suite of yield-generating solutions, which includes the Treasuries Vault for professional firms and the High Yield Vault for growth-focused strategies.

“By launching this first-ever tokenized Blackstone ETF vault, we’re creating new opportunities for users to access institutional yields,” said Teddy Pornprinya, Co-founder at Plume. “Our partnership with Dinari transforms traditionally exclusive products into accessible opportunities through permissionless infrastructure.”

Through this latest vault, users who stake stablecoins into a vault on Nest receive yield tokens that appreciate in value as SRLN.d, Dinari’s tokenized version of the SPDR Blackstone Senior Loan ETF, generates returns. The ETF provides strong downside protection through floating rate yields indexed to SOFR (Secured Overnight Financing Rate).

The vault benefits from SRLN.d’s key features: competitive yields with automatic dividend accrual and reinvestment, full backing by the underlying Blackstone ETF, and guaranteed 1:1 USDC redemption. Blackstone oversees the management of the underlying assets, while Alpaca Securities provides brokerage services for asset transactions.

The floating rate structure provides natural protection against interest rate fluctuations. Blackstone’s ETF is included in a variety of vaults on Nest, where it provides the base level stability and yield. It’s paired with liquidity from yield-bearing stablecoin protocols Mountain and M^0, serving both retail users and liquidity providers.

Nest’s infrastructure has been secured by multiple firms. The protocol’s smart contracts have been audited by SlowMist, while Trail of Bits and Zellic have audited the broader protocol infrastructure. All Nest vaults, including this latest offering, are assessed by institutional risk manager Cicada Partners.

The integration of Dinari’s Blackstone ETF products marks only the beginning of a longstanding collaboration between Nest and Dinari. Future plans include deeper integration through shared global neobank initiatives and expanded access to highly liquid, yield-bearing assets, all powered by Plume’s infrastructure.

This growing partnership will continue to bring institutional-grade investment opportunities to Plume’s expanding ecosystem of protocols and users.

About Nest
Nest is a flagship staking protocol for users to earn RWA yield on their stablecoins. Designed to be a precisionless way for global users to deposit into vaults, the protocol lets fund managers, issuers, and RWA protocols create their own structured offerings. Audited by Trail of Bits and Zellic, Nest leverages Plume’s unique infrastructure to let its global user base participate in traditionally limited asset classes. For more information, visit https://nest.credit and https://x.com/NestCredit

About Dinari
Dinari is at the forefront of delivering innovative digital economy solutions, empowering individuals and organizations alike. With a steadfast commitment to transparency and accessibility, Dinari specializes in blockchain-based offerings, including the pioneering Dinari Securities-Backed Tokens (dShares), ensuring direct exposure to globally esteemed assets with unequivocal 1:1 backing. For more information, visit https://dinari.com

About Plume Network
Plume is the first fully integrated L1 modular blockchain focused on RWAfi, offering a composable, EVM-compatible environment for onboarding and managing diverse real-world assets. With 180+ projects on its private devnet, Plume provides an end-to-end tokenization engine and a network of financial infrastructure partners, simplifying asset onboarding and enabling seamless DeFi integration for RWAs. For more information, visit https://plumenetwork.xyz

CONTACT: press@plumenetwork.xyz

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SOURCE Plume Network

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Strictly Money Launches Crowdcube Campaign, Inviting European Investors to Fuel its Growth Journey

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LONDON, Dec. 27, 2024 /PRNewswire/ — Strictly Money Ltd, the London-based fintech, has launched a crowdfunding campaign on Crowdcube to invite European investors to fuel its next phase of growth. Crowdcube, Europe’s largest private market investment platform, has powered success stories like Revolut, Qonto, and Monzo. Regulated by the UK’s Financial Conduct Authority (FCA), Crowdcube provides a trusted and innovative platform for investors to participate in transformative ventures.

Strictly Money’s primary objective with this campaign is to accelerate its growth, fuel product development, and expand its shareholder base. The funding will enable Strictly Money to launch its payment card and banking app in early 2025 and to strengthen its market presence in Scandinavia, the UK, and Ireland. The company plans to introduce hedge fund returns products, broadening investment options for consumers by the end of 2025.

Discover how you can be part of Strictly Money’s growth journey by visiting our Crowdcube campaign at https://crowdcube.getstrictlymoney.com.

Will Povey, CEO and Co-Founder of Strictly Money, said: “At Strictly Money, our vision is to empower everyday investors with access to wealth-building tools and opportunities that were previously reserved for high-net-worth individuals. With this crowdfunding campaign, we aim to bring together a diverse community of investors who share our passion for financial innovation and inclusivity. This funding will not only help us launch our innovative debit card and app but also drive the development of new products that deliver real value to our users.”

About Strictly Money:

Strictly Money is a UK-based financial technology company set to launch a debit card and a cutting-edge banking app in early 2025. The company aims to democratize access to high-performing hedge fund returns, providing innovative investment strategies and financial solutions tailored to investors, savers, and entrepreneurs. Strictly Money’s mission is to open up premium investment opportunities traditionally limited to high-net-worth individuals (HNWIs). For more information, visit https://strictly-money.com.

For media inquiries contact:
Mary Prendergast
Email: ir@getstrictlymoney.com 

Important Notice: 

Investing in startups and early-stage businesses involves risks, including illiquidity, lack of dividends, loss of investment and dilution. It should be done only as part of a diversified portfolio. Crowdcube is targeted exclusively at investors who are sufficiently sophisticated to understand these risks and make their own investment decisions. Please read the full Risk Warning on Crowdcube’s website before deciding to invest.

Logo – https://mma.prnewswire.com/media/2588210/Strictly_Money_Logo.jpg

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