Caltech Spin-Out Aims to Empower Women with Non-Invasive Hormone Monitoring

LOS ANGELES, Oct. 31, 2024 /PRNewswire/ — Persperity Health, Inc., a new company spun out of Caltech, announced today it has raised $1 million in pre-seed funding to accelerate the development of its groundbreaking sweat-sensing technology, set to transform women’s health by providing real-time, non-invasive hormonal insights. Led by Freeflow Ventures with participation from Caltech, Wilson Hill Ventures, Heritage Group, and ATMA Capital, this investment underscores the revolutionary potential of Persperity’s platform to redefine personalized health monitoring.

Exclusively licensed from Caltech and developed by Dr. Wei Gao and Dr. Cui Ye, Persperity Health’s advanced technology enables real-time hormone monitoring through device-based sweat analysis. This innovation grants women unprecedented access to personalized health data, fundamentally changing how they and their providers can manage fertility and menopause care.

“If you look at what’s commercially available, devices can track heartbeat and steps, but they aren’t capable of studying your health at a molecular level,” said Dr. Wei Gao, co-founder and inventor of the core technology at Persperity Health. “By analyzing sweat, our device provides detailed information about what’s happening inside your body. Once you realize the potential of sweat for health monitoring, it’s hard to go back to conventional methods.”

Sweat contains a wealth of information about hormonal health, including critical hormones like estradiol, progesterone, and luteinizing hormone (LH), which are vital to women’s reproductive health and overall well-being. Persperity’s technology leverages a non-invasive process called iontophoresis to induce sweat on demand, allowing women to monitor their hormone levels anytime, anywhere—without strenuous exercise or invasive procedures.

Persperity Health is also proud to announce its involvement in a prestigious $3 million ARPA-H Spark Award aimed at accelerating innovation in women’s health. Spearheaded by Principal Investigator Dr. Wei Gao at Caltech, the project was one of only 23 awardees selected from over 1,700 global applicants to advance a wearable sweat-sensing system for chronic pain assessment, especially benefiting women.

Dr. Pauline M. Maki, a renowned expert in women’s cognitive health and menopause and a co-investigator on the grant, emphasized the project’s significance, stating: “This innovative technology has the potential to transform women’s health research by enabling, for the first time, the non-invasive collection of biological markers in sweat, including estrogen—a crucial factor in numerous health conditions that disproportionately affect women, such as migraine.”

Dr. Heather Lukas, co-founder and Chief Scientific Officer at Persperity Health, highlighted the broader implications: “We’re not just creating another wearable device; we’re unlocking a new dimension of personalized health monitoring. By making the invisible visible, we’re empowering women to understand their bodies like never before. This is more than a technological advancement—it’s a revolution in women’s health.”

With the infusion of new capital, Persperity Health will accelerate product development, pursue strategic partnerships, and navigate the regulatory approval process. The company’s long-term vision includes expanding its platform to analyze additional biomarkers, with potential applications in mental health, stress management, and early detection of other women’s health issues.

About Persperity Health
Persperity Health is at the forefront of health technology innovation, pioneering sweat-sensing technology to revolutionize continuous health monitoring. Focused on women’s health, the company’s platform delivers real-time, actionable insights into hormonal health, fertility, and menopause. Led by co-founders CEO Shiv Shukla, Dr. Wei Gao, and Dr. Heather Lukas, with clinical collaborator Dr. Pauline Maki, Persperity Health is dedicated to improving how women monitor their health with non-invasive, personalized solutions.

Contact Information
Shiv Shukla
CEO, Persperity Health
press@persperityhealth.com
(818) 466-0080
https://persperityhealth.com/

For more information about Persperity Health and its mission to revolutionize women’s health, visit persperityhealth.com.

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SOURCE Persperity Health, Inc.

SpryPoint has been selected by Local Government Information Systems (LOGIS) to provide its comprehensive suite of utility software solutions. This partnership aims to significantly enhance customer service and improve operational efficiency for LOGIS members, empowering Minnesota’s local governments with the tools needed to better serve their communities.

CHARLOTTETOWN, PE, Oct. 31, 2024 /PRNewswire-PRWeb/ — SpryPoint, a leading provider of cloud-native utility software solutions, is pleased to announce that it has been selected by Local Government Information Systems (LOGIS) to provide its organization members with SpryPoint’s comprehensive utility software suite. This offering enables LOGIS members to improve both customer service and utility operations and includes SpryCIS (customer information system), SpryEngage (customer portal), SpryMobile (mobile field service), and SpryIDM (interval data management).

LOGIS provides technological solutions and support that help Minnesota’s local governments and the communities they serve thrive. In addition to its utility billing application offering, LOGIS offers software solutions that meet financial, human resources, public safety, permitting and inspections, GIS, and other critical needs, as well as a complete package of network services, including infrastructure and system design, security, and other managed services.

“We quickly recognized that LOGIS embodies the ideal membership for collaboration with SpryPoint. LOGIS employs a forward-thinking vision that invests in technology and software to provide best-in-class solutions that improve the lives of both its member’s employees and the local communities they serve,” Kyle Strang, SpryPoint CEO shared, “Through this partnership, member utilities within LOGIS can leverage a trusted relationship, alleviate operational challenges, and deliver an exceptional customer experience using SpryPoint’s suite of cloud-native products”.

Chris Miller, Executive Director of LOGIS commented, “When LOGIS began searching for a new utility CIS system, we conducted a comprehensive review of numerous solutions that might meet our business customers’ everyday needs. SpryPoint emerged as the only product that would replace our legacy system and provide enhanced capabilities that we had sought for many years. Our partnership with SpryPoint strategically positions us to help local communities thrive for the foreseeable future.”

LOGIS member projects are underway with the cities of Waconia and Maple Grove.

About LOGIS

Founded in 1972, LOGIS was created out of individual necessity but continued to grow and evolve through successful collaboration. In the late 1960’s and early 1970’s, local governments struggled to meet their technology needs due to high costs and a lack of software geared towards their unique environment. The solution was to combine resources from multiple government agencies to develop software that met those needs. LOGIS was created to carry out that objective. We understand local government because we are local government. We’re an extension of our members’ staff and helping them succeed is our number one priority.

LOGIS employs a diverse workforce with varied experience, skillsets, and perspectives. We’re committed to providing avenues for personal and professional growth, and opportunities for career advancement. Each employee is asked to participate in our planning processes to ensure member outcomes are improved, and our long-term strategies are fulfilled.

About SpryPoint

SpryPoint is the leading provider of software for public utilities, focusing on delivering innovative and efficient technologies to enable exceptional customer service while optimizing operations. With a robust product line that addresses everything from customer information systems to field service management, SpryPoint is at the forefront of the digital transformation in the utilities sector. To learn more about SpryPoint, please visit us at sprypoint.com, by phone at 1-855-879-7779 (855-TRY-SPRY) or info@sprypoint.com.

Media Contact

Emily Beardsley, SpryPoint, 1 855-879-7779, info@sprypoint.com, www.sprypoint.com

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SOURCE SpryPoint

Recently published in the Journal of Oral Implantology, authors in this study evaluated the precision and predictability outcomes of conventional and dynamic navigation methods for computer-guided implant placements.

LAWRENCE, Kan., Oct. 31, 2024 /PRNewswire-PRWeb/ — Journal of Oral Implantology – Implant dentistry has become the face of modern dentistry when replacing missing teeth. The stability and longevity of implants have revolutionized the industry and allowed dentists to provide better options to patients needing prosthetic rehabilitation. Two approaches to computer-guided implant placements exist: static-guided and dynamic-navigation systems. The static-guided system is a free-hand technique when placing the implant, while the dynamic-navigation system uses computer imaging to guide the placement.

Researchers from Vinshu Dental College in Andhra Pradesh, India, and Sahyog Maxillofacial Center in Maharashtra, India, recently published a study in the Journal of Oral Implantology to assess the use of the static-guided system compared with the dynamic-navigation system. Lead author Gautami S. Penmetsa, MDS, and colleagues state, “Computer-aided implants, a more recent innovation in Implantology, have limited research literature. Hence, there is a dire need to conduct this research to evaluate the precision and predictability outcomes of conventional and dynamic navigation methods.”

Penmetsa et al. conducted a randomized controlled clinical trial in 40 patients needing zygomatic implants. Twenty patients were randomly assigned to a control group using the static-guided system and 20 to the dynamic-navigation system. Inclusion criteria included patients in good physical and oral health; exclusion criteria included poor health, smoking, restricted mouth opening, and a history of head/neck radiotherapy. Upon implant placement, the researchers compared the entry, apex, and angular deviations between both treatment groups.

The results showed statistically significant mean deviations at the entry site in the dynamic-navigation group. At the apex, there was more variation in the static group, and a higher accuracy level was found in the dynamic group regarding angular deviation. The researchers also compared both groups’ right- and left-side accuracy and precision and discovered better predictability for the dynamic group.

This clinical trial shows that the dynamic-navigation system outperformed the static-guided system regarding entry, apex, and angular deviation. These findings lead Penmetsa and colleagues to conclude, “Dynamic navigation technology has proven to be more effective in precision and accuracy, emphasizing that computer-aided implantology will be the future of implant dentistry.” They also note, “Despite the cost and learning curve associated with dynamic navigation technology, its superior predictability in accuracy and precision makes it essential for clinicians to master.”

Full text of the article “Comparative Evaluation of the Accuracy of Dynamic Navigation and Free Hand Methods During Zygomatic Implant Placement: A Randomized Controlled Trial,” Journal of Oral Implantology, Vol. 50, No. 5, 2024, is available at https://doi.org/10.1563/aaid-joi-D-23-00096.

About Journal of Oral Implantology

The Journal of Oral Implantology is the official publication of the American Academy of Implant Dentistry and the American Academy of Implant Prosthodontics. It provides valuable information to general dentists, oral surgeons, prosthodontists, periodontists, scientists, clinicians, laboratory owners and technicians, manufacturers, and educators. The JOI distinguishes itself as the first and oldest journal in the world devoted exclusively to implant dentistry. For more information about the journal or society, please visit: http://www.joionline.org/orimonline/?request=index-html.

Media Contact

Samantha Weinkauf, KnowledgeWorks Global Ltd., 1 785-289-2649, samantha.weinkauf@kwglobal.com

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SOURCE Journal of Oral Implantology