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Linus Health to Demonstrate How Digital Health Powers Innovation at Clinical Trials on Alzheimer’s Disease (CTAD)

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Leaders to deliver four poster presentations showing how its digital health platform lowers investigator burden, enables precision recruitment, and delivers best-in-class outcomes assessments for streamlined and meaningful clinical trials

MADRID, Oct. 29, 2024 /PRNewswire/ — Clinical and research leaders from Linus Health, a digital health company enabling early detection of Alzheimer’s and other dementias, will deliver four poster presentations at a pre-eminent international conference on Alzheimer’s disease taking place this week.

Linus Health leaders will present their findings at the 17th annual Clinical Trials on Alzheimer’s Disease (CTAD) conference, which runs today through this Friday, Nov. 1, in Madrid, Spain. The conference is expected to attract 2,200 leading experts onsite and online to discuss the latest therapeutic advances in Alzheimer’s disease. Scientists from across the globe will present clinical trial results and new therapeutic strategies to treat people experiencing all stages of the disease, as well as the latest on Alzheimer’s prevention.

Posters from Linus Health and other researchers will be on display for in-person viewing on Nov. 1 from 7:15 a.m. to 5 p.m. Central European Time (6 hours ahead of Eastern Standard Time). All posters are also accessible via the CTAD24 digital platform.

“It is a privilege to be invited to present four poster presentations at such a prestigious conference that attracts a large, global audience,” said Linus Health CEO David Bates, PhD. “This honor certainly demonstrates the quality and relevancy of our research. It is also an indicator that the leaders in the field of Alzheimer’s disease and related dementias recognize the growing value of augmenting human clinical expertise with innovative technology to deliver much broader insight into cognitive function with greater efficiency.”

Linus Health poster presentations include:

“Streamlining Recruitment for AD Clinical Trials: Concurrent Detection of Cognitive Impairment and Amyloid-Beta PET Status with a Machine Learning Enabled Digital Cognitive Assessment.” Findings from Director of Cognitive Science Linus Health Ali Jannati, MD, PhD, show that the accuracy of Linus Health’s Digital Clock and Recall™ (DCR™) platform matched blood-based biomarkers in predicting cognitive impairment and were superior or comparable to traditional cognitive tests. The results demonstrate that the DCR effectively streamlines recruitment for clinical trials, offers a cost-effective solution for selecting suitable participants, and reduces screen failure rates.”Incorporating personally defined brain health priorities in clinical trials outcomes: the electronic Person Specific Outcome Measure approach in the U.S.” This study by Chief Medical Officer Alvaro Pascual-Leone, MD, PhD, found heterogeneity in individual-level brain health priorities in the United States. The findings indicate that self-reported confidence in managing personally meaningful priorities may be an appropriate construct to incorporate the person’s voice in study outcomes. They also suggest that Linus Health’s electronic Person Specific Outcome Measure tool supports the establishment of clinical meaningfulness in Alzheimer’s disease trials and is now being validated in other global populations.”Identification of Cognitive Impairment in Alzheimer’s Disease with Drawing and Speech-Based Assessments and Metrics.” The poster from Data Scientist Tanya Talkar, PhD, showcases the benefits of combining speech- and linguistic-based metrics with drawing- and process-based metrics in screening for cognitive impairment. Since the screening can be administered both in the clinic and remotely, it offers researchers accessible, repeated recordings to screen for clinical trials or evaluation of disease-modifying therapies.”Digital Assessment of Cognition for Optimizing Neuropsychology Workflow.” Jannati is presenting another study he led that proposes a workflow involving a technology-enabled psychometry assistant (TPA), a medical assistant equipped with the Linus Health Core Cognitive Evaluation (CCE) and Clinical Decision Support (CDS) system, to streamline the initial cognitive assessment process at the primary care level. The proposed workflow significantly improved the efficiency of neuropsychological evaluations by reducing the workload of specialists, avoiding unnecessary referrals, and prioritizing those that need further assessment.

The 17th annual CTAD conference will take place at the Madrid Marriott Auditorium Hotel and Conference Center, and via the CTAD virtual platform.

To learn more about Linus Health’s research and solutions for clinical trials, or to take a closer look at our platform’s suite of digital assessments, click here

About Linus Health
Linus Health is a Boston-based digital health company focused on transforming brain health for people across the world. By advancing how we detect and address cognitive and brain disorders – leveraging cutting-edge neuroscience, clinical expertise, and artificial intelligence – our goal is to enable a future where people can live longer, happier and healthier lives with better brain health. Linus Health’s digital cognitive assessment platform delivers a proven, practical means of enabling early detection; empowers providers with actionable clinical insights; and supports individuals with personalized action plans. We are proud to partner with leading healthcare delivery organizations, research institutions and life sciences companies to accelerate more proactive intervention and personalized care in brain health. To learn more about our practical solutions for proactive brain health, visit www.linushealth.com or follow us on LinkedIn.

Media Contact
Tara Stultz
Amendola for Linus Health
440-225-9595
tstultz@acmarketingpr.com 

 

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Rockwell Automation unveils innovative solutions at ADIPEC 2024 empowering customers to achieve sustainability goals in their energy transition journey

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DUBAI, UAE, Oct. 30, 2024 /PRNewswire/ — Rockwell Automation, Inc. (NYSE: ROK), the world’s largest company dedicated to industrial automation and digital transformation, and Sensia, Rockwell Automation’s joint venture with SLB, will showcase industry-leading technology and services at ADIPEC 2024, 4-7 November in Abu Dhabi, United Arab Emirates.

The Middle East’s energy sector is rapidly transforming towards a low-carbon future, with technology playing a pivotal role in this shift. For companies to enhance their sustainability efforts, they must have a clear and accurate understanding of their emissions profile, which often relies on real-time data that can be challenging to capture. The answer lies in leveraging the latest automation technologies, robotics, and artificial intelligence to provide the necessary precision and insights and drive meaningful progress.

“At Rockwell Automation, we are committed to supporting companies on their sustainability journey by helping them integrate sustainable practices with operational efficiency,” said Emmanuel Guilhamon, global vice president for sustainability at Rockwell Automation. “Sustainability works best when it makes business sense, driving environmental and economic benefits. Our approach ensures that companies can thrive in a future where collaboration is key; either we all move forward together or risk falling behind.”

Redefining what is possible in manufacturing and production processes

Industrial robots transform manufacturing by enabling smarter, more robust production processes in a safer way. Integrated robotic technology now offers simplified processes and robust, meaningful data, helping producers thrive in a global market.

Robots are critical to addressing significant manufacturing challenges, from navigating skills shortages to enhancing flexible production and handling more SKUs. The future of robot automation lies in connectivity; robots must be as intelligent, intuitive, and integrated as the systems within which they operate.

Rockwell Automation will highlight a Taurob robot on its ADIPEC 2024 stand following its recent partnership agreement with Taurob. This collaboration enables industrial organizations to move toward autonomous operations through advanced robotic solutions. The collaboration between Rockwell Automation and Taurob marks a strategic step towards advancing autonomous industrial operations, leveraging Rockwell’s expertise in digital transformation. Through Kalypso, Rockwell’s digital services arm, the partnership aims to integrate robotic solutions with digital twin and Industrial Internet of Things (IIoT) technologies.

This approach provides a comprehensive framework for automating critical inspection and maintenance tasks, enhancing efficiency and safety while aligning with sustainability goals. By combining Taurob’s ATEX-certified ground robots with Kalypso’s digital capabilities, this initiative underscores Rockwell’s leadership in robotic automation and digital twin solutions, helping clients drive operational excellence and accelerate their net-zero ambitions. 

AI-driven solutions for process industries at ADIPEC 2024

Rockwell Automation will also showcase how AI technologies revolutionize decision-making and operational efficiency in process industries. A key focus will be on their human machine interface (HMI) solutions. The FactoryTalk® Optix ™ platform serves as a crucial enabler of human-machine interface (HMI) solutions by integrating AI-driven processes while prioritizing the human element, allowing operators to maintain intuitive control. This approach enhances visibility and situational awareness across industrial operations, leading to more efficient and informed decision-making.

Rockwell’s AI technologies including the FactoryTalk® Analytics™ LogixAI® and GuardianAI™ solutions enable predictive maintenance and process optimization. LogixAI continuously monitors production operations, making real-time predictions to prevent product quality issues and maintain process integrity. GuardianAI delivers early warnings of equipment failures, allowing maintenance teams to proactively address issues and reduce unplanned downtime.

These advanced solutions empower process industries to stay ahead of equipment failures, improve operational throughput, and enhance production performance.

“At Rockwell Automation, we are excited to collaborate with our customers and our partner ecosystem, supporting all energy actors and heavy industries such as mining, metals, critical minerals and chemical, ” said Sebastien Grau, global industry vice president for process industries at Rockwell Automation. “Our focus is on delivering unified solutions across various verticals, whether lower-intensity fossil energy, green energy, or carbon capture, by connecting our customers into an ecosystem that drives innovation. Through automation and autonomous operations, we bring speed and scale to the energy transition, helping our customers navigate the complexities and disruptions that lie ahead.”

About Rockwell Automation

Rockwell Automation, Inc. (NYSE: ROK), is a global leader in industrial automation and digital transformation. We connect the imaginations of people with the potential of technology to expand what is humanly possible, making the world more productive and more sustainable. Headquartered in Milwaukee, Wisconsin, Rockwell Automation employs approximately 29,000 problem solvers dedicated to our customers in more than 100 countries. To learn more about how we are bringing the Connected Enterprise to life across industrial enterprises, visit www.rockwellautomation.com.

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WITH ANTISEMITISM AT AN ALL-TIME HIGH, JUST AHEAD OF KRISTALLNACHT, IMMERSIVE XR EXPERIENCE LAUNCHES, GIVING VIEWERS UNPRECEDENTED LOOK INSIDE A PIVOTAL MOMENT IN THE HOLOCAUST

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The Claims Conference With Partners, USC Shoah Foundation, Meta, Makemepulse And UNESCO Release A cutting edge Mixed-Reality Experience Detailing The Fear-Provoking Time During And After Kristallnacht – The Night Of Broken Glass.

NEW YORK, Oct. 30, 2024 /PRNewswire/ — Today, just ahead of the 86th anniversary of Kristallnacht, the Conference on Jewish Material Claims Against Germany (Claims Conference) announced the launch of Inside Kristallnacht, an unprecedented, mixed-reality project bringing users inside the Night of Broken Glass, when words of hate led to actions of hate. Viewers will undergo Holocaust survivor and activist, Dr. Charlotte Knobloch’s harrowing experience of survival from Kristallnacht through the end of the Holocaust. This experience, illustrating the dangers of unchecked hate, launches at a time when antisemitism is at an all-time high.

Gideon Taylor, President of the Claims Conference said, “This level of technology isn’t just giving a powerful experience – it provides learning opportunities that can reach an audience in a very personal way. Allowing individuals to feel as though they are on the street in the aftermath of Kristallnacht enables them not just to learn about what happened at the onset of World War II but to understand it in a very immersive way. This is the kind of education we need to reach future generations who will be far removed from the experience of hearing the first-hand testimonies of survivors.”

Dr. Charlotte Knobloch, the Holocaust survivor on which Inside Kristallnacht is based, was born in 1932 in Munich, Germany. She eloquently recounts the night of November 9, 1938, when as a six-year-old she walked through the terrifyingly volatile streets with her father. It was the historic moment when a growing hatred peaked, catalyzing into acts of violence and rage, when citizens turned on their longtime neighbors, roaming the streets in mobs, breaking the glass of Jewish homes and shops. The Claims Conference commissioned the USC Shoah Foundation and immersive technology company makemepulse to create a sensitive and evocative mixed-reality experience animating Knobloch’s memories in a powerful, minimalist way, delivering to users a deeper, more emotional understanding of Knobloch’s survival, of Kristallnacht and of the years that followed.

Dr. Charlotte Knobloch, Holocaust survivor and featured storyteller, said, “Being part of this high-tech experience gives me great pride. There are fewer survivors every year who can share their memories of the Holocaust and knowing that the lessons they have to share will last beyond any of us gives me hope for the future and makes me feel that those lessons will not be lost.”

This immersive project depicts the November Pogroms featuring Dr. Knobloch in dual roles: as the narrator of her own devastating story and as the subject of an interactive interview in which users are able to relive Charlotte’s harrowing story while also asking questions that she will respond to in real-time. Charlotte Knobloch’s memories detail the moments before, during and after this pivotal event in history when words of hate became acts of violence, and more than 30,000 Jews were rounded up and sent to concentration camps marking the onset of the Holocaust.

Greg Schneider, Executive Vice President of the Claims Conference, said, “Preserving Shoah history through emerging technology allows us to provide an experience that educates future generations about the Holocaust and gives users a clear understanding of the impact of unchecked hatred. Using Charlotte’s experience as a background makes the history more relatable and humanizes the devastating toll these key historical moments took on the Jewish population.”

This virtual reality project integrates real-life footage, photographs, music, and other audio of Kristallnacht, as well as meticulously researched historical context, into the hand-drawn world of Dr. Knobloch’s story with stunning artwork created by immersive technology company, makemepulse. When users have questions about the experience they are having, they can engage in an interactive Q&A with Dr. Knobloch that uses natural language processing technology in which her prerecorded answers are matched with the questions. These answers cover diverse topics about Charlotte Knobloch’s experience during Kristallnacht, her family and the Holocaust in general. The mixed-reality project will be displayed in museums and film festivals, and accompanying educational materials are currently under development.

Dr. Robert J. Williams, Finci-Viterbi Executive Director of USC Shoah Foundation, UNESCO Chair on Genocide Education, Advisor to the International Holocaust Remembrance Alliance, said, “The USC Shoah Foundation is proud to partner with the Claims Conference on this immersive experience. This technology transports viewers into one of the most pivotal moments in modern history, the nights of violence and terror during the Holocaust. Initiatives like this can spark interest while fostering a deep connection with the history and relevance of the Holocaust. By embracing technology in ways that are responsible and engaging, we have the potential to enhance our collective memory and ensure that we honor the survivors, the victims and the immeasurable loss suffered during some of the twentieth century’s most tragic years of antisemitic violence.”

UNESCO Director-General Audrey Azoulay, stated, “Charlotte Knobloch’s story reminds us of the imperative to preserve the memory of the Holocaust, at a time when only but a few survivors can testify to their experience. We must also explore the possibilities offered by new technologies to help amplify the voices of survivors, preserve their testimonies and thereby combat Holocaust denial and distortion. It is also by confronting the past that we can prevent antisemitism and future violence. UNESCO is proud to support this innovative initiative as part of its international education program on the Holocaust and genocide.”

Nicolas Rajabaly, Co-Founder, Chief Creative Officer, makemepulse, said, “Inside Kristallnacht, is a groundbreaking project that harnesses the power of XR to bring history to life. This isn’t just about recounting the past—it’s about forging deep, emotional connections with stories of survival and resilience. In a time when empathy and understanding are more critical than ever, this project stands as a powerful reminder of the human spirit’s endurance. Our team is deeply committed to exploring how cutting-edge technology can be a vehicle for storytelling to create experiences that not only preserve history but inspire future generations to learn from it.”

Jordana Cutler, Public Policy Director, Israel & the Jewish Diaspora at Meta, said, “Meta is proud to partner with the Claims Conference on this incredible and unique experience with Charlotte Knobloch. Studies have found that VR can positively improve learning outcomes and this project is a crucial step in transforming Holocaust education. As Metaverse technologies have the potential to change traditional educational models, Claims Conference has again bravely stepped into new territory by bringing Charlotte’s voice and the voices of other survivors, into a platform that will engage and educate future generations.”

Inside Kristallnacht was commissioned by and with assistance from the Conference on Jewish Material Claims Against Germany and supported by the German Federal Ministry of Finance and the Foundation Remembrance, Responsibility and Future.

For more information, please visit: www.claimscon.org

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Finnish VTT in historic collaboration with US entities – commercial fusion energy closer than ever

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ESPOO, Finland, Oct. 30, 2024 /PRNewswire/ — VTT, based in Finland, has been selected as the first-ever foreign partner to join an ARPA-E research program funded by the US Department of Energy, focusing on enabling the commercialisation of fusion energy. Related to the collaboration, VTT and Lawrence Livermore National Laboratory (LLNL) in California, US, have signed a memorandum of understanding for science and technology cooperation. Through these joint projects, VTT’s expertise will play a central role in global technology development.

VTT Technical Research Centre of Finland has joined an ARPA-E (Advanced Research Projects Agency – Energy) program funded by the US Department of Energy, aiming to accelerate the commercial use of fusion energy. The collaboration aims to solve the challenges of materials needed in extreme conditions, which are a bottleneck in the commercialisation of fusion energy.

“Fusion energy is considered the ‘holy grail’ of clean energy, but issues with material durability have slowed breakthroughs for decades,” says Anssi Laukkanen, Research Professor at VTT.

What makes this collaboration particularly exceptional is that the US Department of Energy is directly funding the participation of a European research institution. ARPA-E is known for its top-tier research projects that focus on solving the biggest challenges in the energy sector. This is the first time the US Department of Energy has brought in a foreign partner to this project.

VTT brings its expertise in computational materials engineering and AI-based simulation methods to the initiative. These methods allow for testing the durability of materials in extreme conditions by simulating hundreds of millions of computational experiments.

“The traditional process of developing new materials can take decades. VTT’s simulation and AI technologies shorten the development cycles to months, allowing us to quickly discover, optimise and create case-specific materials tailored to a specific need,” Laukkanen explains.

The project focuses on developing materials for the first wall of fusion reactors, which must withstand extreme temperatures and radiation for several years. The lack of materials that meet these requirements has been a significant barrier to the commercial implementation of fusion reactors.

“Fusion energy has long been a vision that has always been said to be 50 years away. Now research is advancing to the point where the first commercial players expect applications in just 5-10 years from now. If successful, fusion energy could revolutionise energy production and help solve global climate challenges,” Laukkanen says.

VTT and LLNL collaborate to solve critical energy and sustainability issues

The collaboration between VTT and Lawrence Livermore National Laboratory (LLNL) aims to develop revolutionary solutions for both the energy market and sustainable development.

The collaboration covers five key research areas: biotechnology, critical materials and green technologies, quantum computing, energy materials and structural alloys and materials for fusion energy. The agreement is the result of VTT’s particularly strong expertise in developing materials and computational models for extreme conditions.

In material development, VTT uses unique AI-assisted VTT ProperTune computing and simulation technology, which has enabled the development of better material solutions, for example for fusion energy. VTT has also heavily invested in the development of quantum algorithms and software. These factors made VTT an attractive partner.

“The new agreement allows us to deepen our long-standing collaboration and advance research more systematically. Collaboration with a top-tier research institution like LLNL offers a unique opportunity to tackle the critical problems of our time,” says VTT CEO Antti Vasara.

VTT’s involvement in internationally significant research projects raises the profile of European technology in the United States and lays the foundation for new business opportunities in Europe as well.

“For us, this is not just about research, but also about bringing Finnish innovations to international markets. Now, we have an opportunity to be involved in developing new technologies with enormous market potential. The success of even one area could have significant impacts on economic growth,” says Tua Huomo, Executive Vice President of VTT’s sustainable products and materials business area.

Media material

https://vtt.contenthub.fi/ui/shares/w17367579/0l0wyAPYhY/en/ 

LLNL Deputy Director for Science and Technology Pat Falcone, right, and VTT Chief Executive Officer Antti Vasara, sign the MOU on Oct. 1. (Photo: Blaise Douros/LLNL)

For more information, please contact:
Anssi Laukkanen, Research Professor,
+358 40 820 8039, anssi.laukkanen@vtt.fi

Further information on VTT:
Satu Holm-Jumppanen
Manager, Communications
+358 50 305 4718, satu.holm-jumppanen@vtt.fi 
www.vtt.fi

This information was brought to you by Cision http://news.cision.com

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Finnish VTT in historic collaboration with US entities — commercial fusion energy closer than ever

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VTT LLNL MoU Signing 2024 1

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