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Accelerated Model of Age-Related Muscle Loss in Microgravity Could Lead to New Sarcopenia Treatments

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ISS National Lab Enables Valuable Muscle Tissue Chip Studies in Microgravity

KENNEDY SPACE CENTER, Fla., Oct. 16, 2024 /PRNewswire/ — According to the World Health Organization, more than 50 million people around the world have sarcopenia. This age-related condition causes loss of muscle mass, strength, and function and increases the risk of falls and bone fractures. Currently, the only treatment for sarcopenia is exercise. Through ISS National Lab-sponsored research, University of Florida researchers successfully modeled age-related muscle loss using tissue chips in microgravity. The model can be used to test new treatments and study sarcopenia in ways not possible on Earth.

The team’s research is detailed in an article in the latest issue of Upward, official magazine of the ISS National Lab. Principal investigator Siobhan Malany, associate professor in the College of Pharmacy at the University of Florida, commented on the value of space-based research in Upward, saying, “Through insight we gather from microgravity, we can understand not just the end result of [sarcopenia], but really look at the progressive change in young and old cells to see what happens as cells age.”

Age-related muscle changes are hard to study because they happen slowly over decades. In microgravity, muscle deterioration is accelerated, allowing researchers to analyze muscle loss on a much quicker timescale. In a series of investigations funded by the National Institutes of Health, the team developed a muscle tissue chip system and tested whether microgravity-induced muscle loss in space mimics age-related muscle loss on Earth. The tissue chips contained muscle bundles engineered using skeletal muscle cells from young, active adults and older, sedentary individuals. Some tissue chips also contained electrodes that delivered electrical stimulation to induce contraction in the muscle bundles. 

Results showed that in microgravity, several genes associated with human muscle aging on Earth were upregulated (had increased expression) in the tissue chips containing cells from young active adults. These findings validate that the space-based muscle tissue chip system provides an accurate model of age-related muscle loss. The system provides a valuable new tool for researchers to improve their understanding of sarcopenia and test new potential therapeutics. 

Initial findings were published in npj Microgravity, and the team is currently working on several additional publications. Malany recently received an award for these compelling results at the 2024 ISS Research and Development Conference.

See how Malany and her team are using muscle tissue chips in space to help people with sarcopenia on Earth in the Upward feature, “The Beauty of Accelerated Aging.”

Download a high-resolution photo for this release: preparing hardware for flight

About the International Space Station (ISS) National Laboratory:
The International Space Station (ISS) is a one-of-a-kind laboratory that enables research and technology development not possible on Earth. As a public service enterprise, the ISS National Laboratory® allows researchers to leverage this multiuser facility to improve quality of life on Earth, mature space-based business models, advance science literacy in the future workforce, and expand a sustainable and scalable market in low Earth orbit. Through this orbiting national laboratory, research resources on the ISS are available to support non-NASA science, technology, and education initiatives from U.S. government agencies, academic institutions, and the private sector. The Center for the Advancement of Science in Space™ (CASIS™) manages the ISS National Lab, under Cooperative Agreement with NASA, facilitating access to its permanent microgravity research environment, a powerful vantage point in low Earth orbit, and the extreme and varied conditions of space. To learn more about the ISS National Lab, visit our website.

As a 501(c)(3) nonprofit organization, CASIS accepts corporate and individual donations to help advance science in space for the benefit of humanity. For more information, visit our donations page.

Media Contact:         

Patrick O’Neill 

904-806-0035 

PONeill@ISSNationalLab.org

 

International Space Station (ISS) National Laboratory
Managed by the Center for the Advancement of Science in Space, Inc. (CASIS)

6905 N. Wickham Rd., Suite 500, Melbourne, FL 32940 • 321.253.5101 • www.ISSNationalLab.org

 

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SOURCE International Space Station National Lab

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Stoneridge, Inc. To Broadcast Its Third Quarter 2024 Conference Call On The Web

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October 17, 2024

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NOVI, Mich., Oct. 17, 2024 /PRNewswire/ — Stoneridge, Inc. (NYSE: SRI) will webcast its third quarter 2024 earnings conference call live on Thursday, October 31, 2024, at 9:00 a.m. ET with president and chief executive officer, Jim Zizelman, and chief financial officer, Matt Horvath.

The webcast can be accessed on the Presentations & Events page of the Investors section of the Company’s website, www.stoneridge.com. 

Stoneridge, Inc., headquartered in Novi, Michigan, is a global designer and manufacturer of highly engineered electrical and electronic systems, components and modules for the automotive, commercial, off-highway and agricultural vehicle markets. Additional information about Stoneridge can be found at www.stoneridge.com.

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SOURCE Stoneridge, Inc.

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Baylin Technologies Announces Deployment of Multibeam Antennas for Upcoming High-Profile Events at Rogers Stadium, Toronto and BC Place, Vancouver

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October 17, 2024

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TORONTO, Oct. 17, 2024 /CNW/ – Baylin Technologies Inc. (TSX: BYL) (the “Company”) is pleased to announce that its multibeam antennas have been selected for deployment for National Events at both Rogers Stadium, Toronto and BC Place, Vancouver.

The Galtronics multibeam antennas will provide coverage for several upcoming high-profile events, including Taylor Swift concerts in Toronto and Vancouver in November and December of this year.

“Antenna performance is increasingly important at stadiums. With the right connectivity, venue operators elevate the fan experience. Event attendees now expect the stadium experience to allow them to post to social media during the event, and video streaming capabilities are mandatory, not optional.” said Leighton Carroll, Baylin’s CEO.

Baylin’s patented multibeam antennas have now been sold and deployed by all three national carriers in Canada, all three national carriers in the USA and both national carriers in Mexico.

About Baylin

Baylin is a leading diversified global wireless technology company. Baylin focuses on research, design, development, manufacturing and sales of passive and active radio-frequency products, satellite communications products, and supporting services. Baylin aspires to exceed its customers’ needs and anticipate the direction of the market. For further information, please visit www.baylintech.com.

Forward Looking Statements

This press release includes forward-looking information and forward-looking statements (together, “forward-looking statements”) within the meaning of applicable securities laws. Forward-looking statements are not statements of historical fact. Rather, they are disclosure regarding conditions, developments, events or financial performance that we expect or anticipate may or will occur in the future, including, among other things, information or statements concerning our objectives and strategies to achieve those objectives, statements with respect to management’s beliefs, estimates, intentions and plans, and statements concerning anticipated future circumstances, events, expectations, operations, performance or results. Forward-looking statements can be identified generally by the use of forward looking terminology, such as “anticipate”, “believe”, “could” “should”, “would”, “estimate”, “expect”, “forecast”, “indicate”, “intend”, “likely, “may”, “outlook”, “plan”, “potential”, “project”, “seek”, “target”, “trend” or “will”, or the negative or other variations of these words or other comparable words or phrases, and are intended to identify forward-looking  statements, although not all forward-looking statements contain these words.

The forward-looking statements in this press release include statements regarding the quality and performance of the multibeam antennas. Forward-looking statements are based on certain assumptions and estimates made by us in light of the experience and perception of historical trends, current conditions, expected future developments, including projected growth and sales in passive and active radio frequency and terrestrial microwave products and services, and other factors we believe are appropriate and reasonable in the circumstances, but there can be no assurance that such assumptions and estimates will prove to be correct.

Many factors could cause our actual results, level of activity, performance or achievements or future events or developments to differ materially from those expressed or implied by the forward-looking statements, including the risk factors discussed in the Company’s most recent Annual Information Form, which is available on the Company’s profile on SEDAR+ at www.sedarplus.ca. All the forward-looking statements in this press release are qualified by these cautionary statements and other cautionary statements or factors in this press release. There can be no assurance that the actual results or developments will be realized or, even if substantially realized, will have the expected consequences to, or effects on, the Company. Unless required by applicable securities law, the Company does not intend and does not assume any obligation to update these forward-looking statements.

SOURCE Baylin Technologies Inc.

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DFIN to Announce Third-Quarter Results and Host Investor Conference Call on October 31, 2024

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October 17, 2024

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CHICAGO, Oct. 17, 2024 /PRNewswire/ — Donnelley Financial Solutions (NYSE: DFIN) will hold a conference call and webcast on Thursday, October 31, 2024, at 9:00 a.m. Eastern time to discuss its third-quarter fiscal year 2024 financial results, provide a general business update and respond to analyst questions.

A live webcast of the call will also be available on the Company’s investor relations website. Please visit investor.dfinsolutions.com at least fifteen minutes prior to the start of the event to register, download and install any necessary audio software.

If you are unable to participate live, a replay of the webcast will be available following the conference call on the Company’s investor relations website, along with the earnings press release, and related financial tables.

DFIN’s financial report for the third quarter will be released before the market opens on Thursday, October 31, 2024 via a filing with the SEC on Form 8-K and will also be posted on the Company’s investor relations website.

About Donnelley Financial Solutions (DFIN)
DFIN is a leading global provider of innovative software and technology-enabled financial regulatory and compliance solutions. We provide domain expertise, enterprise software and data analytics for every stage of our clients’ business and investment lifecycles. Markets fluctuate, regulations evolve, technology advances, and through it all, DFIN delivers confidence with the right solutions in moments that matter. Learn about DFIN’s end-to-end risk and compliance solutions online at DFINsolutions.com or you can also follow us on X (formerly Twitter) @DFINSolutions or on LinkedIn.

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SOURCE Donnelley Financial LLC

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