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SOPHiA GENETICS Presents Ground-Breaking Multimodal Research on AI-Driven Patient Stratification at ESMO 2024

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Research highlights the use of multimodal machine learning to identify non-small cell lung cancer patients predicted to derive the most benefit from combination immunotherapy

BOSTON and ROLLE, Switzerland, Sept. 14, 2024 /PRNewswire/ — SOPHiA GENETICS (Nasdaq: SOPH), a cloud-native healthcare technology company and a leader in data-driven medicine, will unveil new research at the European Society for Medical Oncology (ESMO) 2024. The study, conducted in collaboration with AstraZeneca, leverages advanced AI-driven techniques to identify subgroups of stage IV non-small cell lung cancer (NSCLC) patients who could most benefit from the addition of tremelimumab to durvalumab and chemotherapy.

The research is a retrospective, multimodal analysis of the POSEIDON Phase 3 clinical trial (NCT03164616). This trial originally demonstrated that the combination of tremelimumab, durvalumab, and chemotherapy significantly increases progression-free survival (PFS) and overall survival (OS) versus chemotherapy in patients with metastatic NSCLC, which lead to approval of this regiment globally in 1L mNSCLC. The SOPHiA GENETICS study used cutting-edge multimodal machine learning models to analyze clinical, biological, genomic, and imaging data, pinpointing patient subgroups who are most likely to benefit from the combination treatment.

The research highlighted signatures identifying patients with non-squamous metastatic NSCLC who may derive higher OS benefit from the addition of tremelimumab to durvalumab plus chemotherapy in the first-line treatment setting. In particular, EGFR wild-type, FGFR3 wild-type, CDKN2A wild-type, KRAS mutation, and STK11 mutation comprised elements of a signature was identified as being associated with a higher OS benefit. These findings could have significant implications for the treatment of NSCLC, as it provides an exploration avenue towards a more tailored approach to patient care.

“Our collaboration with AstraZeneca represents a major step forward in personalized oncology. Non-small cell lung cancer remains one of the most challenging cancers to treat due to its complex biology and the late stage at which it is often diagnosed,” said Jurgi Camblong, Ph.D., Co-founder and CEO of SOPHiA GENETICS. “This study harnesses the power of multimodal data and advanced AI to identify which patients are most likely to benefit from specific therapies. By tailoring treatment strategies based on a patient’s unique multimodal profile, we aim to improve outcomes and offer new hope to those battling this difficult disease.”

The study will be presented as a poster by Ferdinandos Skoulidis, Department of Thoracic Medical Oncology, University of Texas MD Anderson Cancer Center at ESMO 2024 hosted in Barcelona, Spain from September 13-17, 2024. His presentation showcases the operational feasibility and clinical impact of large-scale multimodal analyses in identifying heterogeneous treatment effects in oncology.

For more information on SOPHiA GENETICS, visit SOPHiAGENETICS.COM, or connect on LinkedIn.

About SOPHiA GENETICS 
SOPHiA GENETICS (Nasdaq: SOPH) is a cloud-native healthcare technology company on a mission to expand access to data-driven medicine by using AI to deliver world-class care to patients with cancer and rare disorders across the globe. It is the creator of the SOPHiA DDM™ Platform, which analyzes complex genomic and multimodal data and generates real-time, actionable insights for a broad global network of hospital, laboratory, and biopharma institutions. For more information, visit SOPHiAGENETICS.COM and connect with us on LinkedIn.

SOPHiA GENETICS products are for Research Use Only and not for use in diagnostic procedures unless specified otherwise. The information in this press release is about products that may or may not be available in different countries and, if applicable, may or may not have received approval or market clearance by a governmental regulatory body for different indications for use. Please contact support@sophiagenetics.com to obtain the appropriate product information for your country of residence. 

SOPHiA GENETICS Forward-Looking Statements: 
This press release contains statements that constitute forward-looking statements. All statements other than statements of historical facts contained in this press release, including statements regarding our future results of operations and financial position, business strategy, products, and technology, as well as plans and objectives of management for future operations, are forward-looking statements. Forward-looking statements are based on our management’s beliefs and assumptions and on information currently available to our management. Such statements are subject to risks and uncertainties, and actual results may differ materially from those expressed or implied in the forward-looking statements due to various factors, including those described in our filings with the U.S. Securities and Exchange Commission. No assurance can be given that such future results will be achieved. Such forward-looking statements contained in this press release speak only as of the date hereof. We expressly disclaim any obligation or undertaking to update these forward-looking statements contained in this press release to reflect any change in our expectations or any change in events, conditions, or circumstances on which such statements are based, unless required to do so by applicable law. No representations or warranties (expressed or implied) are made about the accuracy of any such forward-looking statements.

 

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SOURCE SOPHiA GENETICS

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Automotive Seat Heater Market to Reach $5.5 Billion, Globally, by 2033 at 6% CAGR: Allied Market Research

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Key factors contributing to the growth of the automotive heat seater market include advancements in heating technology, such as the integration of more efficient heating elements and improved temperature control systems.

WILMINGTON, Del., Sept. 20, 2024 /PRNewswire/ — Allied Market Research published a report, titled, “Automotive seat heater Market by Type (Carbon Heater and Composite Heater), Vehicle Type (Passenger Cars and Commercial Vehicles), and Sales Channel (OEM and Aftermarket): Global Opportunity Analysis and Industry Forecast, 2024-2033″. According to the report, the automotive seat heater market was valued at $3.1 billion in 2023, and is estimated to reach $5.5 billion by 2033, growing at a CAGR of 6% from 2024 to 2033.

The global automotive seat heaters market is driven by increased demand for comfort and customization. As increasing numbers of individuals utilize the roads, the number of affordable vehicles available in recent years has skyrocketed. As a result, there is a greater need for vehicles with interiors that are both visually appealing and practical. The market for vehicle interior materials is being driven by rising consumer demand for customization and technical developments across the industry. In response to client demand, companies are now offering customization choices for creating modern interiors. Consumers increasing health consciousness is also driving the development of environmentally friendly automotive interior materials that contribute to increased comfort. 

Request Sample of the Report on Automotive Seat Heater Market   Forecast 2033: https://www.alliedmarketresearch.com/request-sample/A323768

Prime determinants of growth 

The growing level of competition in the automotive industry is a primary driver of the automotive seat heater market’s expansion. Furthermore, improving consumer affordability, rising consumer income, and the availability of easy financing to purchase a vehicle are all driving forces in the global automobile sector. Furthermore, expansion in the automobile industry causes growth in the global market. Rising popularity of carbon fiber technology, rising demand for comfort and energy efficiency in vehicles, and rising preferences for high-end passenger cars are some of the major and insightful factors that will most likely drive the growth of the automotive seat heater market during the forecast period. The health benefits, such as reduction from discomfort backs and rapid warming, are driving market expansion. The expanding aftermarket sales of car seat heaters are driving the market forward.

Have a Question? Connect to our Analyst – https://www.alliedmarketresearch.com/connect-to-analyst/A323768

By Type 

The carbon heater segment is expected to grow faster throughout the forecast period.

The carbon heater segment is anticipated to experience faster growth in the automotive seat heater market. Carbon fiber meshed weave heating pads will remain the largest market segment as this type of seat heater ensures good strength and requires very low voltage to produce heat. a growing preference for energy-efficient and environmentally friendly components, aligning with the broader push towards sustainable automotive solutions. The integration of advanced technologies, such as automatic climate control systems that adjust seat heating based on ambient temperature and individual preferences, is becoming increasingly popular.  

By Vehicle Type

The passenger car segment is expected to grow faster throughout the forecast period.

The passenger car segment is anticipated to experience growth in the automotive seat heater market. The increasing expenditure on passenger and driver comfort. The development of premium features and the surge in passenger vehicle numbers in Europe and North America significantly contribute to this growth. Additionally, there is a rising demand for SUVs and luxury vehicles in emerging markets. Automotive manufacturers are continuously innovating electronic technologies, which create new opportunities for the application of heated seats in passenger cars. This trend is further bolstered by the emphasis on enhancing vehicle comfort and the integration of advanced climate control systems. 

Procure Complete Report (324 Pages PDF with In-depth Insights, Charts, Tables, and Figures): https://www.alliedmarketresearch.com/checkout-final/automotive-seat-heater-market-A323768

By Sales Channel

The aftermarket segment is expected to grow faster throughout the forecast period.

The aftermarket segment is anticipated to experience growth in the automotive seat heater market. One of the standardization of temperature control seats in various mid-range and high-end vehicles is helping the OEM section of the automobile seat heater industry. Seat heater replacement rates are predicted to rise due to excessive wear and tear, as well as changing climatic circumstances in cold locations, driving up aftermarket sales. When compared to OEM products, aftermarket products are more cost-effective. Furthermore, owners of vehicles without seat heaters add this equipment in the aftermarket, which boosts seat heater aftermarket sales.

By Region

Europe to maintain its dominance by 2033.

Europe is expected to maintain its dominance in the automotive heat seater market by 2033 owing to robust industrialization, infrastructural development, and growing investments in automotive and manufacturing sectors. has witnessed a surge in the popularity and necessity of automotive seat heaters. As the nation’s economy expands and consumer prosperity grows, there is a corresponding increase in the demand for vehicles equipped with advanced comfort amenities. Once considered a luxury, seat heaters are now becoming more accessible to a wider demographic, fueling their adoption among consumers.

Europe will maintain its pivotal role as a significant market for automotive seat heaters. This is primarily due to the increasing demand from end users who prioritize cabin comfort, especially in the winter months. Seat heaters are favored for their ability to significantly enhance occupant comfort during this season.

Players: –

Continental AGPanasonic CorporationGentherm IncorporatedII-VI IncorporatedRoadwire LLCRostra Precision Controls Inc.Firsten Automotive Electronics Co., Ltd.Guangzhou Tachibana Electronic Co., Ltd.SINOMASChampion Auto Systems

The report provides a detailed analysis of these key players in the global automotive seat heater market. These players have adopted different strategies such as new product launches, collaborations, expansion, joint ventures, agreements, and others to increase their market share and maintain dominant shares in different regions. The report is valuable in highlighting business performance, operating segments, product portfolio, and strategic moves of market players to showcase the competitive scenario. 

Recent Industry News

In August 2020, Lear and Gentherm introduced INTU™ Thermal Comfort Seating with ClimateSense™ Technology.

For More In-depth Insights: https://www.alliedmarketresearch.com/automotive-seat-heater-market-A323768

AVENUE- A Subscription-Based Library (Premium on-demand, subscription-based pricing model) Offered by Allied Market Research:

AMR introduces its online premium subscription-based library Avenue, designed specifically to offer cost-effective, one-stop solution for enterprises, investors, and universities. With Avenue, subscribers can avail an entire repository of reports on more than 2,000 niche industries and more than 12,000 company profiles. Moreover, users can get an online access to quantitative and qualitative data in PDF and Excel formats along with analyst support, customization, and updated versions of reports.

Get an access to the library of reports at any time from any device and anywhere. For more details, follow the link: https://www.alliedmarketresearch.com/library-access

About Allied Market Research:

Allied Market Research (AMR) is a full-service market research and business-consulting wing of Allied Analytics LLP based in Wilmington, Delaware. Allied Market Research provides global enterprises as well as medium and small businesses with unmatched quality of “Market Research Reports” and “Business Intelligence Solutions.” AMR has a targeted view to provide business insights and consulting to assist its clients to make strategic business decisions and achieve sustainable growth in their respective market domains. AMR offers its services across 11 industry verticals including Life Sciences, Consumer Goods, Materials & Chemicals, Construction & Manufacturing, Food & Beverages, Energy & Power, Semiconductor & Electronics, Automotive & Transportation, ICT & Media, Aerospace & Defense, and BFSI.

We are in professional corporate relations with various companies and this helps us in digging out market data that helps us generate accurate research data tables and confirms utmost accuracy in our market forecasting. Allied Market Research CEO Pawan Kumar is instrumental in inspiring and encouraging everyone associated with the company to maintain high quality of data and help clients in every way possible to achieve success. Each and every data presented in the reports published by us is extracted through primary interviews with top officials from leading companies of domain concerned. Our secondary data procurement methodology includes deep online and offline research and discussion with knowledgeable professionals and analysts in the industry.

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/R E P E A T — MEDIA ADVISORY – Minister Wilkinson to Make a Critical Minerals Infrastructure Announcement/

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VANCOUVER, BC, Sept. 19, 2024 /CNW/ – The Honourable Jonathan Wilkinson, Minister of Energy and Natural Resources, and Ranj Pillai, the Premier of Yukon, will make a funding announcement in support of critical minerals infrastructure projects. A media availability will follow.

Date: September 20, 2024

Time: 10:30 a.m. PT

All accredited media are asked to pre-register by emailing media@nrcan-rncan.gc.ca. A dial-in line is available for media and will be provided upon registration.

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SOURCE Natural Resources Canada

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Olink Proteomics Announces the ‘Olink Proteomics World’ Virtual Conference: A Novel Platform Exploring the Latest Advancements in Proteomics and Proteogenomics

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The ‘Olink Proteomics World’ Virtual Conference will bring together scientists from around the globe to explore the latest advancements in proteomics and proteogenomics across fields such as immunology, oncology, neuroscience, aging, and inflammation on September 26th, 2024.

WALTHAM, Mass., Sept. 20, 2024 /PRNewswire-PRWeb/ — Olink Proteomics, part of Thermo Fisher Scientific, a leading provider of advances proteomics solutions, is exited to announce its upcoming virtual conference, Olink Proteomics World, on September 26th, 2024.

The digital event features presentations from esteemed scientists and provides a platform to connect with peers, identify potential collaborations, and explore advanced protein biomarker discovery tools and results.

This innovative virtual conference will bring together scientists from around the globe to explore the latest advancements in proteomics and proteogenomics across fields such as immunology, oncology, neuroscience, aging, and inflammation. The digital event features presentations from esteemed scientists and provides a platform to connect with peers, identify potential collaborations, and explore advanced protein biomarker discovery tools and results.

Our lineup of esteemed presenters will cover a wide range of topics, including:

The Aged Tumor Microenvironment: Understanding how aging influences the tumor microenvironment and its implications for cancer therapy.Infectious Diseases Dynamics: Unravelling how proteomics can enhance our understanding and management of infectious diseases.Alzheimer’s Diagnostics and Disease Monitoring: Exploring the latest tools and biomarkers for early detection and monitoring of Alzheimer’s disease.Aging Mechanisms: Insights into the biological processes of aging and how they can inform healthcare strategies.Predicting Disease Risks: Utilizing multiomics data to forecast disease risks and improve preventive measures.Genetics and Proteomics of Obesity: Investigating the complex interplay between genetics, proteomics, and obesity.Microbiome Transplantation Effects: Evaluating the impact of faecal transplants on human health and disease.Biomarker Discovery in Multiple Sclerosis: Cutting-edge research on identifying biomarkers for better diagnosis and treatment of Multiple Sclerosis.

In addition to these topics, our speakers will delve into various aspects of multiomics research, offering insights into how integrated approaches are shaping the future of personalized medicine and healthcare.

To see the full agenda and list of speakers for this event click here.

In addition to expert presentations, attendees can participate in interactive sessions, visit the digital poster hall, and engage in real-time Q&A sessions with speakers.

For further information about the event & to register for free, click here.

About Olink Proteomics
Olink’s mission is to accelerate proteomics together with the scientific community, to understand real-time biology and gain actionable insights into human health and disease. Our innovative solutions deliver highly sensitive and accurate protein quantification, giving scientists the power to investigate complex biological processes with precision.

About Labroots
Labroots is the leading scientific social networking website, & primary source for scientific trending news & premier educational virtual events & webinars & more. Contributing to the advancement of science through content sharing capabilities, Labroots is a powerful advocate in amplifying global networks & communities. Founded in 2008, Labroots emphasizes digital innovation in scientific collaboration & learning. Offering more than articles & webcasts that go beyond the mundane & explore the latest discoveries in the world of science, Labroots users can stay atop their field by gaining continuing education credits from a wide range of topics through their participation in the webinars & virtual events.

Media Contact

Akshay Masand, Labroots, 714-463-4673, akshay.masand@labroots.com, https://olink.com/ 

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SOURCE Labroots

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