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Science in Space to Cure Disease on Earth–the International Space Station National Lab and NASA Announce New Funding Opportunity

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Joint solicitation will award up to $4 million for biomedical R&D leveraging the orbiting laboratory

KENNEDY SPACE CENTER, Fla., Aug. 15, 2024 /PRNewswire/ — The International Space Station (ISS) National Laboratory is collaborating with NASA on a solicitation for space-based research addressing some of the most significant diseases of our time—such as cancer, cardiovascular disease, and neurodegenerative disease. ISS National Lab Research Announcement (NLRA) 2024-09: Igniting Innovation: Science in Space to Cure Disease on Earth, released in partnership with NASA’s Biological and Physical Sciences division, is aimed at overcoming challenges hindering progress in disease prevention, diagnosis, and treatment. This NLRA will offer up to $4 million in total funding for an expected two to three awards for multiflight translational and transformative research and technology development.

Through this joint solicitation, the ISS National Lab and NASA seek projects that leverage the space environment to improve existing or develop new technologies that help solve health problems on Earth. Therapies for cancer and cardiovascular, immune, muscle and bone, and neurodegenerative diseases face obstacles that thwart scientific advancements and the translation of research findings into clinical applications. These challenges frequently overlap and share common elements, despite the complexity and variability of mechanisms within and among these diseases. Many of these challenges can be mitigated using accelerated disease models in microgravity through ISS National Lab resources.

This NLRA aims to foster collaboration between academia, industry, and government to develop innovative, commercially viable products and technologies to improve medical outcomes on Earth. Below are topics of particular interest for this NLRA:

Enhanced Models to Study Disease Mechanisms: It is difficult to unravel the intricate dynamics of disease onset and progression and to identify effective therapeutic targets. Leveraging microgravity to improve cell-based models like tissue chips and organoids could deepen understanding of disease mechanisms and lead to personalized therapies.Population and Disease Heterogeneity: Population and disease heterogeneity pose significant obstacles to drug discovery. Variability in genetic and demographic factors, such as age and sex, leads to differing treatment responses across individuals. Genetic and phenotypic diversity in diseases themselves must also be considered.Drug Screening and Development: Microgravity enables high-throughput drug screening in 3D cell cultures and tissue models that more accurately simulate the human body. Innovative approaches and technologies to identify preclinical drug candidates are needed to accelerate development of new, more effective therapeutics.Drug Delivery: Innovation in drug delivery, such as nanotechnology and targeted therapies, is vital to enhance treatment precision and reduce side effects. Additionally, the absence of well-defined biomarkers complicates treatment selection, and innovative strategies for biomarker discovery are needed to improve treatment outcomes.Drug Resistance and Toxicity: Drug resistance poses significant challenges in treating many diseases. For example, cancer cells can become resistant due to genetic mutations or changes in signaling pathways, decreasing drug efficacy. Additionally, the toxicity of treatments like chemotherapy requires careful balancing of efficacy and adverse effects.

Last month, at the annual ISS Research and Development Conference in Boston, the ISS National Lab and NASA announced five projects selected through the inaugural Igniting Innovation NLRA, which sought to harness the unique space environment to advance cancer research to benefit patients on Earth.

“We are proud to collaborate again this year with NASA’s Biological and Physical Sciences division on this important initiative to bring the transformative power of space-based inquiry into the fight against diseases that touch all of our lives,” said ISS National Lab Chief Scientific Officer Michael Roberts. “Our inaugural solicitation in 2023 resulted in the selection of five innovative concepts to leverage microgravity and the space station to benefit patients on Earth. We look forward to enabling access to even more ideas that ignite innovation and fuel research and development for the benefit of humanity.”

“Space-based research has a long history of contributing to advancements on Earth,” said Lisa Carnell, director of NASA’s Biological and Physical Sciences division. “Continuing the Igniting Innovation solicitation could contribute to the next big leap in disease therapies. We are excited to collaborate with the ISS National Lab on this endeavor to help address some of the biggest health challenges facing the world today.” 

This research announcement will follow a three-step proposal submission process (Step 1A: Concept Summary, Step 1B: Technology Roadmap, and Step 2: Full Proposal). Step 1A: Concept Summaries must be submitted by end of day on September 26, 2024.

Those interested in learning more about this research announcement can register for a webinar hosted by the ISS National Lab on August 22, 2024, at 1 p.m. EDT.

For more information on this funding opportunity and how the space-based environment can accelerate research and technology development for the benefit of life on Earth, please visit the official solicitation page.

To download a high-resolution image for this release, click here.

About the International Space Station (ISS) National Laboratory:
The International Space Station (ISS) is a one-of-a-kind laboratory that enables research and technology development not possible on Earth. As a public service enterprise, the ISS National Laboratory® allows researchers to leverage this multiuser facility to improve quality of life on Earth, mature space-based business models, advance science literacy in the future workforce, and expand a sustainable and scalable market in low Earth orbit. Through this orbiting national laboratory, research resources on the ISS are available to support non-NASA science, technology, and education initiatives from U.S. government agencies, academic institutions, and the private sector. The Center for the Advancement of Science in Space™ (CASIS™) manages the ISS National Lab, under Cooperative Agreement with NASA, facilitating access to its permanent microgravity research environment, a powerful vantage point in low Earth orbit, and the extreme and varied conditions of space. To learn more about the ISS National Lab, visit our website.

As a 501(c)(3) nonprofit organization, CASIS accepts corporate and individual donations to help advance science in space for the benefit of humanity. For more information, visit our donations page.

Media Contact:

Patrick O’Neill 

904-806-0035 

PONeill@ISSNationalLab.org

 

International Space Station (ISS) National Laboratory

Managed by the Center for the Advancement of Science in Space, Inc. (CASIS)

6905 N. Wickham Rd., Suite 500, Melbourne, FL 32940 • 321.253.5101 • www.ISSNationalLab.org

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SOURCE International Space Station National Lab

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Nuvve Updates Shareholders on Compliance Measures

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SAN DIEGO, Sept. 24, 2024 /PRNewswire/ — Nuvve Holding Corp. (Nasdaq: NVVE), a leader in vehicle-to-grid (V2G) technology, has issued a letter to shareholders regarding actions taken to regain compliance with Nasdaq’s Bid Price Rule. 

Nuvve recently executed a 1-for-10 reverse stock split, resulting in 652,727 shares outstanding. The Company encourages shareholders to protect their shares against market manipulation through actions such as holding shares in cash accounts and requesting “no loan” status. 

For shareholder letter: https://nuvve.com/shareholder-letter/  

For more information, contact investors@nuvve.com

About Nuvve Holding Corp. Nuvve (Nasdaq: NVVE) transforms electric vehicles into grid resources, driving the transition to a net-zero future. Learn more at nuvve.com 

View original content to download multimedia:https://www.prnewswire.com/news-releases/nuvve-updates-shareholders-on-compliance-measures-302257834.html

SOURCE Nuvve Holding Corp.

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Wire and tube industry expos to spark international trade in Shanghai

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SHANGHAI, Sept. 25, 2024 /PRNewswire/ — The wire China 2024 and Tube China 2024, organized by Shanghai Electric Cable Research Institute Co., Ltd., Messe Düsseldorf (Shanghai) Co., Ltd., Metallurgical Council of the China Council for the Promotion of Int’l Trade (MC-CCPIT), are scheduled to be held from September 25 to 28 at the Shanghai New International Expo Centre, aiming to drive industry advancement and foster connections.

This year, the two expos will span 10 pavilions, encompassing a total exhibition area of 109,250 square meters. Nearly 1,500 businesses from about 30 countries and regions are expected to participate. The two exhibitions will cover the entire industry chain of cables, wires and tubes, offering a professional and efficient one-stop platform for exchanges worldwide.

wire China 2024: supporting enterprises to foster new quality productive forces

The wire China 2024 event is poised to occupy an area of 80,500 sqm, setting a milestone in its growth trajectory. With the participation of nearly 1,100 enterprises from 26 countries and regions, the expo will serve as a platform to showcase the latest developments and trends in the industry.

The exhibition will showcase an array of offerings including wire and cable manufacturing and processing machinery, auxiliary cable processing equipment, raw and auxiliary materials for cables (optical cables), finished wire products and cables, measurement and control technology, testing engineering solutions. The showcase is designed to assist enterprises in accelerating their transition toward digitalization, fostering flexibility, enabling smart production, nurturing new quality productive forces and enhancing the production competitiveness of businesses. The 2024 edition will cover five major areas: Digital Intelligent & Innovative Equipment, Technology Tools & Auxiliary Materials, Green and Low-carbon Solutions, Wires & Cables and Measures & Control Technology.

China has been promoting development of new quality productive forces since the start of 2024, with burgeoning sectors like artificial intelligence; new materials; commercial aerospace; the low-altitude economy and smart connected vehicles. These innovations are infusing the wire industry with vitality and drawing the attention of numerous overseas enterprises to China. This year, the event will host businesses from countries and regions such as South Korea, Japan, the United States, Switzerland, the United Kingdom, Spain and Turkiye. Business delegations from Germany, Italy, France and Austria will be present at the W1 Pavilion to exhibit their innovations and latest breakthroughs.

Heavyweight participants

This year, the event has garnered robust backing from prominent industry associations, including the Asian Wire & Cable Industry Corporation Alliance (AWCCA); Germany’s Federal Ministry for Economic Affairs and Climate Action (BMWK); the Association of the German Trade Fair Industry (AUMA); the German Mechanical Engineering Industry Association (VDMA); the ITA/ICE-Italian Trade Agency (ITA); the Italian Wire Machinery Manufacturers Association (ACIMAF) and the Austrian Federal Economic Chamber (WKÖ).

List of some well-known participating brands:

NIEHOFF, WAFIOS, SIKORA, MAILLEFER, ROSENDAHL NEXTROM, BOROUGE, SAMP, PROTON, ELANTAS, ENEOS NUC, HANWHA, TOTOKU, KOS, MFL GROUP, TEIJIN ARAMID, ZUMBACH, EUROLLS, SWPG, ESTEVES, SHENG CHYEAN, PETROFER, HUNTSMAN, DSR, SMATER, SINGCHEER, HONTA, G.Y.M., HANDING, JCDOFAMA, XINGMING, GOLDEN TECHNOLOGIES , INOVANCE, DONY GROUP, LIQIANG MECHANICAL & ELECTRICAL, AEROSPACE NANHAI, YI TENG ELECTRIC, HUAYUAN, PANGHAO, WANMA MACROMOLECULE, TIANRONG, CGN GROUP, CABLE, ORIGINAL, PAMICA, QLPM, ATPOIMER, etc.. 

(*Information is updated as of August 31st, 2024. Listing is in no particular order)

Fostering new quality productive forces

Centering on digital intelligence and innovation, the expo will be a key platform to display products and services. Singcheer will introduce the SiMOM for remote collaborative manufacturing operations and an AGV logistics system tailored for the cable industry. Maillefer from Finland will showcase the latest AI panoramic scanner 2.0, while Inovance from Shenzhen will present a motorized cable extrusion solution using advanced control algorithms and the MD810 multi-drive. These digital intelligence and innovation products cover manufacturing equipment, industrial software, visual inspection and other specific businesses, empowering cable companies to transit toward intelligent manufacturing.

Leading new trends

The wire China 2024 is not just a trade platform, but a place to communicate the latest market trends and release new products and solutions. This year, there will be nearly 60 high-end technological communication events.

The annual China Wire and Cable Industry Annual Conference will have in-depth discussions on new quality productive forces and high-quality development. Participants will share opinions on new market opportunities and challenges, exchange insights on the market trends, analyze the development status of the wire and cable industry, release annual reports on the development of international and domestic cable standardization work, as well as business competitiveness analysis reports. Simultaneously, the conference will address quality and technical issues related to typical products, unveil significant common technical research accomplishments and identify challenges and hurdles in emerging technological domains within the cable industry. The event aims to inspire businesses, bolster their confidence, foster courage in confronting challenges, and contribute to enhancing the development standards of both the industry chain and the supply chain.

The themed forums for wire and cable businesses will cover industrial economics and the development of the cable industry; the role of intelligent equipment in supporting high-quality development; green and low-carbon innovations in cable materials; high-quality special materials aiding the development of new energy vehicles; efficient and energy-saving electrical equipment; cable industry resource recycling technologies and digital intelligence empowering the development of the cable manufacturing industry.

Tube China 2024: 20 years of companionship, jointly shaping the new future of the industry.

As one of leading professional expos for tubes in Asia, Tube China 2024 has a total exhibition area of 28,750 sqm. Nearly 400 brands from 13 countries and regions including Germany, Japan, South Korea, Italy, the Netherlands, Latvia, Norway, Switzerland, and the United Kingdom will participate in the event. Tube China will present a high-level industry feast of intelligence and tube manufacturing for the Chinese tube industry and its upstream and downstream sectors.

This year, the expo will welcome some first-time participants including Fanuc. Industry-leading players including Fanuc, IPG, Kinkelder, Stark, Inductotherm, SINOAUDE, Halifax Fan and ENRX will bring their latest developments to the event. Enterprises such as IPG, Changen, Longxin, Huibaisheng and Huinengda will focus on showcasing innovative products and applications related to lasers and optoelectronics; optics and optical manufacturing; testing and quality control; as well as the innovative products and application solutions of infrared technology and applications.

List of some well-known participating brands:

FANUC, IPG, KINKELDER, STARK, INDUCTOTHERM, SINOAUDE, HALIFAX FAN, ENRX, HUIBAISHENG, SINOFORM, CHANGEN, HANDUK, KTM, TOYOKOHAN, TAELIM, VICTAULIC-TUWEI, TEMA, DONGAN, FIELD, AMPCO, ARES, JINYI, SONGYANG STAINLESS STEEL INDUSTRY ASSOCIATION, CHENLONG, ZHONGYONG, CHANGFENG, WAN-RUN DA , BOKENA, TUS PIPE, LONGXIN, NANYANG, CONTOR M & E, SHENGTIAN, NEW VICTOR, HUAYANG, HUILITONG, BAOFENG, JINCHUANG XINTIAN, HAIQIANWEI, FUGANG, ASCENDING, JUYI, LIWAN, VICTORY, ZHONGHAO, YOUFA, etc..

(*Information is updated as of August 31st, 2024. Listing is in no particular order)

Concurrent events, including the China International Steel Tube & Pipe Summit and the 2024 Heat Treatment Technology Seminar, will be organized during the expo to enhance communication, foster partnerships, drive technological innovation and uphold high-quality development within the industry.

A variety of activities will be organized to celebrate the 20th anniversary of the annual expo and the longstanding support from all participants of the expo.

Looking ahead, organizers of wire & Tube China will continue to promote development of the event to promote exchanges and bolster quality development of the industry.

View original content:https://www.prnewswire.com/apac/news-releases/wire-and-tube-industry-expos-to-spark-international-trade-in-shanghai-302255418.html

SOURCE Messe Düsseldorf Shanghai

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PayMongo and Brankas Now Offer the Widest Range of Payment Options in the Philippines

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Enable seamless, secure, and direct online banking payments with Brankas through PayMongo, featuring top Philippine banks BDO, Metrobank, and Landbank.

MANILA, Philippines, Sept. 25, 2024 /PRNewswire/ — PayMongo has partnered with Brankas to add new payment options to the PayMongo platform, making it the payment gateway with the widest range of payment options for Filipino businesses. PayMongo payment options include credit cards, e-wallets, BNPL, QRPh, and online banking. PayMongo merchants can now accept direct online banking payments from three additional Philippine banks — BDO, Metrobank, and Landbank — offering greater convenience and flexibility for both merchants and customers.

eCommerce stores, food delivery websites, ride-hailing apps, and gaming platforms that are PayMongo merchants can accept more forms of payments by integrating Brankas Direct API. This pay-by-bank channel is another trusted payment method that makes transactions faster and enhances the overall payment experience for users.

“Brankas and PayMongo share the same commitment to deliver fast and secure payment experience for users. Offering more payment options is a win-win for both customers and merchants as we offer greater payment flexibility and customer reach at the same time.” said Todd Schweitzer, Brankas CEO and Co-founder.

How to Get Started with Brankas Direct

To start accepting direct online banking payments, existing PayMongo merchants simply need to contact PayMongo Customer Support to request the activation of BDO, Metrobank, and Landbank payment options. The feature is available for Shopify plug-in users, PayMongo’s Custom & Checkout API, PayMongo Pages, and PayMongo Links. Users of the custom API require minimal updates, and the PayMongo developer website provides the full details.

Ready to enhance your payment offerings and provide a better customer experience? Enable Brankas Direct through PayMongo now. Visit Brankas Direct or PayMongo to learn more.

About PayMongo

PayMongo is a leading financial infrastructure platform in the Philippines, designed to simplify how businesses manage their finances. From payment processing to embedding financial services, PayMongo provides solutions that enable businesses to accept payments both online and in-person, streamline financial operations, and drive profitability. By offering a wide range of payment options and seamless integration, PayMongo empowers businesses to grow their revenue and succeed in the digital economy.

About Brankas 

Brankas is a leading global open finance technology provider. We provide API-based solutions, data and payments solutions for financial service providers (like banks, lenders and e-wallets) and online businesses. Brankas partners with banks to build and manage their open finance infrastructure, producing APIs for real-time payments, identity and data, new account opening, remittances, and more. With Brankas’ secure open banking technology, online businesses, fintech companies and digital banks can use Brankas APIs to create new digital experiences for their users.

Media Enquiries: 

Yiyang Teo
yiyang.teo@brank.as

View original content to download multimedia:https://www.prnewswire.com/apac/news-releases/paymongo-and-brankas-now-offer-the-widest-range-of-payment-options-in-the-philippines-302255016.html

SOURCE Brankas

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