Technology

Pusan National University Researchers Explore the Interplay Between High-Affinity DNA and Carbon Nanotubes

Published

5 months ago

July 26, 2024

Researchers demonstrate the intricate interactions between single-stranded DNA sequences and carbon nanotubes

BUSAN, South Korea, July 26, 2024 /PRNewswire/ — Single-walled carbon nanotubes (SWCNTs) have emerged as promising candidates for applications in biotechnology and nanoelectronics due to their exceptional physical and chemical properties. Despite their potential, challenges like insolubility and toxicity have hindered their widespread use. Prior studies have been investigating diverse strategies to functionalize and modify the surfaces of SWCNTs to overcome these challenges.

In a recent study, researchers from the Pusan National University led by Professor Sanghwa Jeong, Assistant Professor in the School of Biomedical Convergence Engineering, have attempted to fill this gap. This study has gone beyond conventional techniques by employing high-throughput screening methods to elucidate the relationship between DNA sequences and their binding affinity to carbon nanotubes. It focused on optimizing the binding affinity and stability of these constructs through advanced sequence design and molecular dynamics simulations. This recent study was published in the journal of Advanced Science on 25th June 2024. Discussing the background of their study Dr. Jeong explains, “Researchers have been exploring various strategies to engineer SWCNT surfaces to overcome the challenges of limited applications owing to insolubility and potential toxicity. One promising approach is the use of single-stranded DNA (ssDNA) as a wrapping surfactant for SWCNTs.”

The researchers employed a rigorous methodology to ensure precise characterization and optimization of single-stranded DNA (ssDNA)-SWCNT complexes. Initially, a diverse random 30-nucleotide (nt) ssDNA library underwent iterative rounds of screening to identify high-affinity sequences.

Computational modeling, particularly molecular dynamics simulations, provided insights into the structural dynamics of the SWCNT constructs. Furthermore, the researchers used several machine-learning models to understand the pattern of sequences that affect binding affinity. They have successfully created a freely accessible online service that predicts the binding affinity of ssDNA sequences to SWCNTs. These integrated approaches not only validated the experimental findings but also guided the design of high-performance ssDNA-SWCNT constructs.

The findings revealed significant advancements in the stability and functionality of ssDNA-SWCNT complexes. High-affinity 30-nt ssDNA sequences, rich in adenine and cytosine, exhibited superior binding strength, validated through surfactant displacement experiments. Molecular dynamics simulations highlighted the formation of stable intramolecular hydrogen bonds near the SWCNT surface, underscoring their enhanced structural integrity. The machine-learning models effectively predicted the binding affinities of ssDNA sequences, further supporting the design of the tailored ssDNA-SWCNT constructs.

Moreover, the study demonstrated notable improvements in the resistance of these complexes to enzymatic degradation compared to free ssDNA, making them highly suitable for long-term biological applications.

In conclusion, the development of high-affinity ssDNA-SWCNT constructs marks a significant advancement in nanobiotechnology. The exceptional characteristics of ssDNA-SWCNTs make them ideal candidates for cell or tissue-specific drug delivery systems as well as the development of high-performance nano electronic devices.

Dr. Jeong concludes, “Our study not only makes a substantial contribution to our understanding of the interplay between ssDNA and SWCNTs but also offers practical avenues for harnessing these interactions in a wide range of advanced technologies. In the future, developing nanomaterials and devices with enhanced stability will show promise in driving innovation in nanoelectronics and biotechnology.”

Reference
Title of original paper: Systematic Selection of High Affinity ssDNA Sequences to Carbon Nanotubes
Journal: Advanced Science

DOI: https://doi.org/10.1002/advs.202308915

About the institute
Website: https://www.pusan.ac.kr/eng/Main.do

Contact:
Jae-Eun Lee
82 51 510 7928
380885@email4r.com

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SOURCE Pusan National University

Technology

Rovshan Rasulov, Founder and CEO of Rgand, Joins the Forbes Business Council

Published

1 hour ago

January 1, 2025

Rovshan Rasulov, Founder and CEO of Rgand, an expert in technological entrepreneurship specializing in building and strategically scaling trading and logistics platforms across industries, has been invited to join the Forbes Business Council, one of the world’s premier communities for business leaders.

MIAMI, Jan. 1, 2025 /PRNewswire-PRWeb/ — Rovshan Rasulov, Founder and CEO of Rgand, an expert in technological entrepreneurship specializing in building and strategically scaling trading and logistics platforms across industries, has been invited to join the Forbes Business Council, one of the world’s premier communities for business leaders.

“It’s a tremendous honor to join the Forbes Business Council,” said Rovshan Rasulov. “This recognition motivates me and my team to continue delivering cutting-edge solutions to our clients and driving innovation in the industry.”

Rovshan is widely recognized as the visionary behind the Rgand Marketplace, Sample Box Marathon, and Direct Trade Foundation, pioneering technologies that redefine sales strategies. In 2023, he was honored with an award for his groundbreaking innovations in sales technology.

The Forbes Council selection committee recognized Rovshan for his exceptional business achievements and his impactful contributions to the industry. His membership highlights his professionalism, leadership, and commitment to excellence throughout his career.

About Rgand

Rgand is an online wholesale marketplace that connects food producers directly with U.S. restaurants, eliminating middlemen such as wholesalers and distributors.

The platform offers services like Rgand Prime Fulfillment, which provides integrated warehousing and same-day fulfillment solutions for businesses on the Rgand Marketplace. The innovative Sample Box Marathon enables producers to streamline their entry into the restaurant industry supply chain by delivering curated sample boxes directly to potential buyers.

In September 2024, Rgand announced a $100 million accelerator program to support global suppliers entering the U.S. market.

About Forbes Councils

Forbes Councils is a collective of invitation-only communities that bring together exceptional business leaders, connecting them with the resources, insights, and networks needed to thrive and achieve their goals.

Media Contact

Rgand LLC, Rgand LLC, 1 (754) 226-6700, company@rgand.com, https://www.rgand.com/

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SOURCE Rgand LLC

Technology

Ushering 2025 in a New High: OneOdio Studio Max 1 Breakthrough and OpenRock X Forbidden City Edition at CES 2025

Published

4 hours ago

January 1, 2025

HONG KONG, Jan. 1, 2025 /PRNewswire/ — OneOdio, a professional DJ headphone brand with a decade of expertise, together with its dynamic sports sub-brand, OpenRock, is gearing up to dazzle attendees at CES 2025 (Jan. 7-10). Visit Booth #31106, South Hall 1, to explore how these two brands are setting a new standard for audio innovation, presenting their cutting-edge products to the world’s largest technology stage.

OneOdio and ShowStoppers at CES 2025

This year, OneOdio is taking its CES 2025 presence to new heights. In addition to showcasing its latest innovations at the booth, the brand will shine at the exclusive ShowStoppers event on January 7, 2025, from 6:00 PM to 10:00 PM PST at Booths #D07 & D09. This high-energy media reception connects top tech companies with over 1,000 leading journalists and industry influencers.

Introducing the Unmatched Studio Max 1: The Best of CES 2025

A centerpiece of OneOdio’s display at CES 2025 will be its latest flagship headphone, the Studio Max 1. Co-branded with Italian DJ Arianna, who has already performed with it in two major European events, this model redefines professional audio, with its most important features outlined below.

Rapid WiLL+ Connection Technology: Super 20ms ultra-low latency, seamless audio
LDAC & Dual Hi-Res Certification: Studio-grade sound, capturing every detail in high-resolution clarity.
4-in-1 Functionality: Switch between Wireless DJ, Bluetooth, Wired Monitoring, and Wired DJ modes for maximum versatility.

With other features like Dual-Mic ENC Noise Reduction and 120-hour battery life, Studio Max 1 keeps DJs fully focused on their performance, lasting for days without recharging. All of these advantages have been recognized by Gadgety Awards and AndroidHeadlines Technology Awards, with it earning the prestigious title of The Best of CES 2025, underscoring its exceptional innovation and performance in the audio technology world.

OpenRock X: Award-Winning Design with Sports in Mind

OpenRock X, OpenRock’s flagship model, was honored with the Good Design Award 2024, a prestigious accolade from Japan that has celebrated excellence in design since 1957. Its innovative adjustable ear-hook design ensures a secure, non-slip fit, making it the ideal companion for sports lovers.

Main Features of OpenRock X – Forbidden City Limited

Taking its innovations further, OpenRock has also presented the Forbidden City Limited version of the OpenRock X. This unique edition blends cultural artistry with superior engineering, making it a standout product in both aesthetics and performance. The version will be showed at CES 2025.

Join Us at CES 2025

Discover how OneOdio and OpenRock are setting new benchmarks in professional and sports audio at CES 2025. Follow us on Facebook and Instagram for the latest updates, and enjoy an exclusive 50% OFF CES discount (code: ATFCUG5N) on the Pro C in champagne gold on Amazon US from January 1–10. Plus, explore other premium audio gear with special CES discounts.

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SOURCE OneOdio

Technology

TESSAN x Rachael Yamagata: Inspiring Charging Moments of Innovation and Connection

Published

4 hours ago

January 1, 2025

NEW YORK, Jan. 1, 2025 /PRNewswire/ — As the new year unfolds, the leading charging solution brand TESSAN proudly announces an inspiring collaboration with the American singer-songwriter Rachael Yamagata. Together, they are embarking on a journey of innovation, encouraging people to discover and engage with the world around them.

Rachael Yamagata has made a significant impact on the global music scene with her soulful and emotionally resonant songs. Her music, characterized by its raw honesty and heartfelt lyrics, has garnered a dedicated international fanbase. Rachael has toured extensively and has a strong following. Her ability to connect deeply with audiences through her music has solidified her place as a beloved and influential artist on the global stage.

For Rachael, a journey represents the balance between planning future destinations and appreciating the present moment. It is a rich tapestry of life, interwoven with new encounters and personal growth. This vision aligns seamlessly with the “connection” concept of TESSAN’s mission, resulting in a strong partnership between TESSAN and Rachael.

Rachael’s experiences as an international traveler have shaped her perspective on the essentials needed for a seamless journey. She emphasizes the importance of efficient packing when traveling, particularly for tours. “You can only take so much because you go on trains, planes, you’re walking through cities, you’re getting cabs, you’re literally changing cities every day,” she shared.

One of Rachael’s main travel challenges is balancing the need to bring essential items without overpacking. TESSAN’s WTA series travel adapter emerges as an indispensable companion to address such challenges during modern travelers’ global exploration. As a user of the WTA series, Rachael finds the series highly appealing due to its excellent connectors, lightweight design, compact size, durability, fast charging capabilities, and ability to charge multiple devices simultaneously.

Weighing only 0.62lb and featuring a compact design, the WTA series fits easily into any luggage. Its classic slider design includes EU, UK, and US plugs, with rotatable pins for sockets in Australia and China, ensuring compatibility worldwide. GaN technology contributes to its lightweight nature and enables faster charging while maintaining a stable temperature, preventing overheating. The WTA series can simultaneously charge multiple devices, including iPhones, Macs, iPads, cameras, and CPAP machines. Built-in safety features, such as double-patented 10A auto-resetting fuses, provide peace of mind when using high-power devices.

As part of the collaboration, TESSAN conducted an exclusive interview with Rachael, capturing the entire process in a documentary. On January 4th, the documentary will premiere on YouTube, offering a glimpse into Rachael’s journey and insights. Through this exchange, TESSAN encourages audiences to ponder “What’s Your Next Journey,” inspiring them to embark on new explorations as a New Year’s resolution.

To support this initiative, TESSAN is launching a series of activities aimed at inspiring users to share the stories in their journeys. Including the sharing of the documentary trailer released on YouTube on January 1st allows participants to enter a prize draw. Then, on January 4th, the TESSAN website will showcase a limited time offer on the WTA series. The excitement will reach its peak on January 8th with a TikTok live event, featuring giveaways of prizes and Rachael Yamagata posters.

This collaboration between TESSAN and Rachael Yamagata is an invitation to explore, connect, and discover new horizons. As the new year begins, it calls for individuals to embark on their own journeys, starting from the comfort of home and reaching out to the world.

About TESSAN

TESSAN, a trusted partner in charging solutions, is committed to enriching experiences both at home and during travel. The brand offers a wide array of products, including multifunctional power strips, travel adapters, wall extenders, and smart home devices. Supported by a robust R&D and production team, TESSAN develops innovative socket products for users across the globe. With the trust of over 20 million users, TESSAN empowers their journeys from home to every destination, promoting environmentally conscious electricity usage.

For more information, visit www.tessan.com or the TESSAN Amazon store, and follow TESSAN on Facebook, Instagram, and YouTube.

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SOURCE TESSAN