Connect with us

Technology

CytoSite Bio Announces Agreement with Lantheus for Granzyme B Targeted PET Imaging Radiotracer for Immunotherapy Assessment

Published

on

A global collaboration agreement has been signed for the development and commercialization of a Granzyme B-targeted Positron Emission Tomography (PET) imaging radiotracer.

This radiotracer has the potential to support the monitoring of patient immune response and supports the accelerated development for CytoSite.

CytoSite will lead initial clinical development with Lantheus having an exclusive option to acquire worldwide development and commercialization rights to the radiotracer.

BOSTON, March 26, 2025 /PRNewswire/ — CytoSite Bio (CytoSite) announced today that they have signed a collaboration agreement for the clinical development and potential commercialization of CytoSite’s investigational Phase 1 ready granzyme B-targeted Positron Emission Tomography (PET) imaging tracer with Lantheus Holdings, Inc. This agreement provides Lantheus with an exclusive option to license worldwide rights to CytoSite’s novel imaging technology.

The two companies will collaborate on clinical development, with Lantheus having the option to acquire exclusive worldwide rights for further development and commercialization of the product. Under the terms of the agreement, CytoSite is eligible to receive payments for development, regulatory and commercial milestones, plus royalties on future product sales.

Granzyme B is an enzyme released upon activation of immune cells to destroy harmful cells, including cancer. Early studies of the investigational imaging tracer have shown potential to evaluate whether immunotherapies are working effectively to activate the immune system. This investigational PET imaging radiotracer could enable physicians to measure the early efficacy of such therapies within days of first dose and modify treatment accordingly rather than waiting for months to fully understand if the treatment is working. Additionally, pharmaceutical developers can use the investigational imaging tracer to gain an early read-out of efficacy for new therapies, enabling faster decision-making and more efficient allocation of resources.

“The clinical data we have generated to date validates our belief that use of PET imaging to detect active Granzyme B has the potential to transform outcomes in immuno-oncology, autoimmune-mediated and inflammatory diseases,” said Benjamin Larimer, PhD, Co-founder and CEO of CytoSite. “We are excited to be partnering with Lantheus to bring Granzyme B PET imaging to the forefront. This strategic collaboration creates a clear path to commercialization with an ideal partner in the radiopharmaceutical space while providing significant value potential for CytoSite as we advance this promising technology in parallel with our own radiotherapeutic program.”

“If approved, CytoSite’s proprietary Granzyme B biomarker could provide a valuable tool for oncologists, radiologists and medical professionals to enable improved outcomes for cancer patients and rapidly expand options for new immunotherapies,” said Umar Mahmood, MD, PhD, Co-founder of CytoSite, Chief of Nuclear Medicine and Molecular Imaging in the Department of Radiology at Massachusetts General Hospital (MGH) and Professor of Radiology at Harvard Medical School.

About CytoSite Bio

CytoSite Bio is developing novel radiopharmaceuticals that enable the quantification and modulation of immune activation to improve cancer immunotherapy. The lead product detects active Granzyme B, the primary protein responsible for the killing of tumor cells by the immune system. CytoSite’s products enable individually optimized treatments for patients, and more rapid evaluation of new drugs and drug combinations, using non-invasive, whole-body PET imaging combined with targeted radiotherapy.

For more information: www.cytositebio.com

Contacts:
Ben Larimer, PhD
CEO, CytoSite Bio
781-608-9916
blarimer@cytositebio.com

View original content:https://www.prnewswire.com/news-releases/cytosite-bio-announces-agreement-with-lantheus-for-granzyme-b-targeted-pet-imaging-radiotracer-for-immunotherapy-assessment-302412492.html

SOURCE CytoSite Bio

Continue Reading
Click to comment

Leave a Reply

Your email address will not be published. Required fields are marked *

Technology

Local Moving Company in San Jose Earns Customer Loyalty Award

Published

on

By

ALL REASONS MOVING & STORAGE awarded Top Quality Award

SAN JOSE, Calif., March 30, 2025 /PRNewswire-PRWeb/ — ALL REASONS MOVING & STORAGE, an agent of Wheaton World Wide Moving, recently earned the distinctive Customer Loyalty Award, an award from the van line honoring moving companies that achieve a Net Promoter Score® (NPS) of 70 or above.

All Reasons Moving & Storage earned a Customer Loyalty Award, while achieving a Net Promoter Score of 70; almost unheard of in the service industry.

“An NPS score of 70 is almost unheard of in the service industry,” said Mark Kirschner, CEO of Wheaton World Wide Moving. “We’re proud to announce that ALL REASONS MOVING & STORAGE has garnered this rating from customers through their exceptional work in 2024.”

The Customer Loyalty program is designed to recognize moving companies in the Wheaton World Wide Moving network that offer the highest possible quality experiences to those using their services. Agents must receive at least ten responses throughout the program year and meet or exceed the van line’s average response rate.

ALL REASONS MOVING & STORAGE is located at 600 East Trimble Road, San Jose CA 95131 and can be reached at 408-240-0244 or online at www.allreasonsmoving.com.

About Wheaton World Wide Moving

Wheaton | Bekins is one of the world’s most highly regarded providers of transportation services. The van line owns five household goods relocation brands, Wheaton World Wide Moving, Bekins Van Lines, Stevens Worldwide Van Lines, Arpin Van Lines and Clark & Reid. The van line is the fourth largest household goods carrier. Headquartered in Indianapolis, Ind., through its brands Wheaton | Bekins offers private and corporate domestic and international household goods relocation services as well as special commodities and logistic services. The United States military is one of the company’s largest customers. The van line is partner to more than 350 Wheaton and Bekins agents nationwide. To learn more, visit www.wheatonworldwide.com/why-wheaton/partners.

Media Contact

Jo Torres, Top Shelf Logic, 1 4694552777, jo@topshelflogic.com, https://topshelflogic.com/

View original content:https://www.prweb.com/releases/local-moving-company-in-san-jose-earns-customer-loyalty-award-302414717.html

SOURCE Wheaton World Wide Moving

Continue Reading

Technology

Ligent Inc. and Hisense to Showcase Innovations at OFC 2025

Published

on

By

Ligent Inc. and Hisense will be showcasing their latest innovations at the 2025 Optical Fiber Communication Conference and Exhibition (OFC) from March 30th to April 3rd. You can find them at booth #4321 and OIF’s booth #5745. Additionally, they will present a leading research paper at the event.

SAN JOSE, Calif., March 30, 2025 /PRNewswire-PRWeb/ — Ligent Inc., a global leader in optical transceivers, active optical cables (AOCs), ONTs, and Terminal Devices, is excited to announce its participation in the Optical Fiber Communication Conference and Exhibition (OFC) 2025. Ligent will be showcasing a series of groundbreaking demos highlighting its latest advancements in high-speed optical communication.

“We’re here to lead, innovate, and showcase how our cutting-edge technologies support and empower our customers” Dr. Jin Hong, CEO and President of Ligent.

Featured Demos at Booth #4321:

1.6T OSFP 2xDR4 Silicon Photonics and EML-based fully and half re-timed: Demonstrating unmatched performance and efficiency for next-generation AI clusters.1.6T 2xVR4 VCSEL and peek into 400G per Lane for 3.2T Transceivers: Showcasing advancements with 200G VCSELs and 400G TFLN modulators, setting the stage for high-capacity, ultra-efficient future data centers.800G QSFP-DD ZR & LR4: Live demonstrations of long-range, high-capacity optical connectivity for demanding DCI/metro applications.Interoperability of 400/800G fully re-timed, LPO and half re-timed LRO or TRO: Featuring products like 800G 2xFR4/2xDR4 Silicon Photonics-based LPO, 800G 2xFR4 EML-based half retimed LRO or TRO, and 800G 2xFR4/2xDR4 EML-based fully retimed with I3C support.

Interop Demos at Booth #5745:

In addition to these demos, Ligent Inc. and Hisense will also participate in OIF interoperability demonstrations:

CEI-448G, 224G, and 112G: Multi-vendor demos of 224Gbps and 112Gbps CEI across various applications, including a live 448G demo for AI network scaling. Featured products include OSFP 1.6T 2xDR4+ Silicon Photonics half retimed LRO or TRO, and OSFP 1.6T 2xDR4+ Silicon Photonics fully retimed.800ZR, 400ZR, and Multi-Span Optics: Showcasing advancements in pluggable coherent optics interoperability, featuring 800ZR and 400ZR applications, and multi-span connections like OpenZR+, 100ZR, and 800G OpenROADM (PCS). Featured products include the 800G QSFP-DD ZR.CMIS: Demonstrating physical layer management interoperability across diverse network equipment and pluggable modules, highlighting the CMIS industry-standard management interface. Featured products include the 800G 2xSR4/2xDR4+/2xFR4 LPO.

Research Presentation:

Ligent will unveil an important research paper by Dr. Jianying Zhou and his team, titled “Performance Limitations and Optimizations of Linear Driver Optics for 200G/Lane and Beyond.” This presentation, scheduled for March 31 at 10:30 AM in room 213-214, will explore the challenges and solutions for optimizing 1.6T LPO optics, paving the way for future AI and cloud applications.

“Our presence at OFC 2025 shows our new commitment to our vision to be a leading force in the optical connectivity space,” said Dr. Jin Hong, CEO and President of Ligent. “We’re here to lead, innovate, and showcase how our cutting-edge technologies support and empower our customers. At Ligent, our mission is clear: to align deeply with our customers and provide solutions that exceed expectations.”

Media Contact

Media Relations, Ligent, 1 4083530623, mediarelations@ligent.com, www.ligent.com

View original content:https://www.prweb.com/releases/ligent-inc-and-hisense-to-showcase-innovations-at-ofc-2025-302415075.html

SOURCE Ligent

Continue Reading

Technology

BFA’s 10th Religious Sub-forum Highlights Global Digitization Project of Buddhist Scriptures

Published

on

By

QIONGHAI, China, March 30, 2025 /PRNewswire/ — The Sub-forum on Religious Harmony and Mutual Learning Among Civilizations took place at the BFA (BFA) Annual Conference 2025 on March 28. The sub-forum focused on the theme “Countless Dharma Doors Converge in a Square Inch: A Discussion on the Future of Digitization Project of Buddhist Scriptures.” The gathering brought together 12 eminent monks and cultural researchers from six countries and regions to explore the current state and future of digitizing Buddhist scriptures. Chaired by Venerable Master Yin Shun, Vice President of the Buddhist Association of China, and President of the Buddhist Association of Hainan Province, the event aimed to advance the preservation and development of Buddhist culture through international collaboration.

 

BFA’s Decade of Progress: A Solid Foundation for the Future

Yin Shun, reflecting on the ten-year journey of the BFA Religious Sub-forum, noted its steadfast commitment to the foundational goal of building a global community united by a common destiny. The sub-forum has been instrumental in promoting religious harmony and fostering cross-cultural dialogues, while also enhancing international cooperation in the fundamental domains of religion, culture, education, philanthropy, and healthcare. A notable achievement of the sub-forum has been in the area of digital preservation and accessibility of Buddhist teachings. It has effectively used digital technology to compile the Encyclopedic Dictionary of Chinese Buddhist Terms and has facilitated the digital translation of Buddhist classics across the economically important Pan-South China Sea region. Furthermore, it has proposed initiatives to raise the digitization of these texts as a major national concern. The South China Sea Buddhist Academy, China’s premier international Buddhist educational platform targeting Southeast Asia, has made significant contributions by educating 106 international students from several nations, most notably from Laos, Mongolia, Cambodia, and Nepal, and, by doing so, playing a crucial role in the international effort to digitize Buddhist scriptures.

Digital Empowerment: Advocating for the Chinese Adaptation of Buddhism

Ven. Guang Quan, Deputy Secretary General of the Buddhist Association of China and President of the Buddhist Association of Zhejiang Province, noted the crucial role of digitizing Chinese Buddhist scriptures in enhancing the international dissemination of Buddhist culture. He highlighted the accomplishments of Hangzhou Lingyin Temple in this area, including the development of an AI-based OCR engine for ancient books, production and tool platforms for digitizing ancient books, and a Buddhist scriptures reading hub. Building on these advancements, efforts are underway to digitize Buddhist canons, citing, in particular, the Jingshan Canon, the Yongle Northern Canon and the Siji Canon. Guang Quan’s initiatives aim to further the interconnection of civilizations through digital technology, breathing new life into Asian Buddhist wisdom in the digital realm.

Bhikshu HUIMIN, President, Comprehensive Buddhist Electronic Text Archive Foundation (CBETA) Taiwan, China, reflected on the establishment of the Electronic Buddhist Text Initiative (EBTI). He provided an overview of the current status of global Buddhist text digitization, highlighting its evolution from digital archives (DA) to digital humanities (DH). Additionally, he unveiled the groundbreaking concept of Artificial Intelligence and Brain-Computer Interface (AI – BCI) for the digitization of Buddhist culture. He stressed that the transition of Buddhism from traditional scriptures to cloud-based platforms represents not only the future of Buddhism but also a new civilization where mindfulness and technology merge.

Hong Xiang, Research Assistant at the Centre of Buddhist Studies, The University of Hong Kong, highlighted the transformative impact of digital technology on the collation and proofreading of the Dunhuang manuscripts, starting from the digitization project. He noted that the preservation of the Dunhuang manuscripts, which embody the essence of a multi-faceted and symbiotic civilization, demands interdisciplinary collaboration. Moreover, he advocated for global resource sharing in the digitization of Buddhist scriptures.

Zhu Cuiping, Editor-in-Chief of Zhonghua Book Company GuLian (Beijing) Digital Media Tech Co., Ltd, China, pointed out that the digitization of Buddhist scriptures is an enormous undertaking that requires a collaborative effort among the government, religious organizations, universities, research institutes, and publishing entities. She called for the initiation of a global initiative to compile Buddhist literature to drive the worldwide project of digitizing Buddhist scriptures.

International Cooperation: Jointly Advancing the Global Digitization Project of Buddhist Scriptures

The sub-forum placed particular emphasis on the contributions of Japanese and Korean Buddhism to the digitization of Buddhist scriptures. KAWANAKA KOKYO, Director-General of Administration of Jodoshu, Japan, presented the “Digitization of Zōjō-ji’s Three Great Buddhist Canons” project. He urged all parties to collaborate in furthering the global effort to digitize Buddhist scriptures, with the aim of fostering a more peaceful and harmonious future for humanity.

JONG-RIM, Honorary Chairman of Tripitaka Koreana Research Institute, Jogye Order of Korean Buddhism, shared insights from the digitization efforts of the Tripitaka Koreana at Haeinsa Temple in Korea. He proposed the future goal of completing a comprehensive Tripitaka and developing a dictionary of concepts and terms utilizing digital technology.

South China Sea Buddhist Friendship Circle: Fostering Digital Connections

The sub-forum highlighted the role of the South China Sea Buddhist Friendship Circle in the digitization of Buddhist scriptures. Ven. PHRAPROMMASITH (Thongchai Sukkayano) Supreme Patriarchs, elaborated on Thailand’s experience in safeguarding Buddhist cultural heritage. He urged international cooperation to facilitate the digitization of Buddhist scriptures, aiming to provide convenient access to anyone anywhere with an interest in reading and better understanding the Dharma.

SANDI MARBHIVAMSA, Chairman of Sangha Maha Nayaka Committee, Myanmar, and Ven. (Dr.) KIRINDE ASSAJI, Chief Prelate (Malwatta Chapter) Sanghanayaka of Sri Lanka’s Western Province, provided insights into the current state of Buddhism in their respective countries and the advancements made in the digitization of Buddhist scriptures. They both expressed a strong willingness to collaborate with Buddhist communities from other nations in these endeavors.

Looking to the Future: Consultation, Collaboration, and Sharing

Ven. YAN JUE, President of the Buddhist Association of China, concluded by emphasizing that Buddhist scriptures represent a shared cultural heritage of humanity. He noted that their digitization presents not only a technical challenge but also a cultural mission. He also underscored the commitment of the Chinese Buddhist community to the global governance principles of consultation, collaboration, and sharing. By partnering with Buddhist and academic communities worldwide, they aim to advance the digitization of Buddhist texts, share the outcomes of these efforts, and further disseminate the teachings and scriptures of Buddhism.

View original content to download multimedia:https://www.prnewswire.com/news-releases/bfas-10th-religious-sub-forum-highlights-global-digitization-project-of-buddhist-scriptures-302415071.html

SOURCE The Buddhist Association of Hainan Province

Continue Reading

Trending