Connect with us

Technology

Study published in the New England Journal of Medicine AI Concludes that the Sepsis ImmunoScore™, the First FDA-Authorized AI Tool for Sepsis, has both significant Diagnostic and Predictive Power

Published

1 month ago

on

Groundbreaking NEJM AI Study Highlights the Ability of Prenosis’ Sepsis ImmunoScore™ to Holistically Predict Adverse Outcomes, Ushering in a New Era of Predictive Sepsis Tools Powered by AI

CHICAGO, Dec. 4, 2024 /PRNewswire/ — A new study published in the New England Journal of Medicine AI (NEJM AI) concluded the Sepsis ImmunoScore™, the first FDA-authorized AI diagnostic for sepsis, has high accuracy for the diagnosis of sepsis and for prediction of key adverse patient outcomes, concretely demonstrating the benefit of AI to inform sepsis care. Sepsis, an overactive immune response to infection, costs the U.S. healthcare system billions of dollars annually and claims the lives of at least 350,000 people each year—more than all cancers combined.

The peer-reviewed study—FDA-Authorized AI/ML Tool for Sepsis Prediction: Development and Validation—found the Sepsis ImmunoScore™ has high accuracy for sepsis diagnosis and simultaneously predicted critical outcomes, including mortality during hospitalization, length of stay before discharge, ICU admission, need for mechanical ventilation, and use of vasopressors. This represents the first time an FDA-authorized tool for sepsis can predict all of these critical outcomes simultaneously.

This milestone publication underscores the potential of Prenosis Inc.’s Sepsis ImmunoScore™ to transform sepsis management by presenting providers with trustworthy predictive information, allowing them to shift from a reactive to a proactive approach to care.

While single biomarkers, such as Procalcitonin (PCT), have been valuable tools in diagnosing sepsis for over two decades, they have limitations when trying to predict the future. The study demonstrated the combination of multidimensional inputs—vital signs, lab data, and sepsis-specific biomarkers—into a comprehensive AI-driven tool provides more reliable diagnostic information and is predictive of future patient outcomes.

“The Sepsis ImmunoScore™ is the first FDA-authorized sepsis AI algorithm that functions by embedding in the EMR and is approved to aid providers in the identification and assessment of patients with sepsis,” said Nathan I. Shapiro, MD, MPH, a Professor of Emergency Medicine at Harvard Medical School and attending physician in the Department of Emergency Medicine at Beth Israel Deaconess Medical Center, and the paper’s corresponding author1.

“For too long, clinicians have struggled with the early and accurate prediction of adverse outcomes due to sepsis, a complex, rapidly progressing condition,” said Bobby Reddy, Jr., Prenosis Co-Founder and CEO. “By delivering FDA validated AI results with transparency and explainability for clinicians, tools like the Sepsis ImmunoScore™ offer critical insights to improve patient outcomes.”

“Hospitals and clinicians now have access to the first-ever FDA-authorized, peer-reviewed AI solution that provides unmatched insights into sepsis risk and prediction of the negative outcomes associated with sepsis,” said Akhil Bhargava, the study’s lead author. “This study confirmed that AI, when validated, can be a reliable, comprehensive tool to assist providers with identification of patients at high risk of sepsis and prediction of sepsis-related adverse outcomes,” added Bhargava, Prenosis’ Senior Data Scientist — Applied Machine Learning.

About the Sepsis ImmunoScore™

FDA-authorized via the De Novo pathway in April 2024, the Sepsis ImmunoScore™ outputs a combination of both diagnostic and predictive information previously unavailable in a legally marketed device for sepsis. Unlike early warning systems that alert clinicians to potential sepsis with high amounts of false positives, leading to alert fatigue, the Sepsis ImmunoScore™ delivers actionable and trustworthy insights. The Sepsis ImmunoScore™ works in concert with a clinician’s suspicion of serious infection, providing information exactly when needed for decision-making.

The Sepsis ImmunoScore™ was built using Prenosis’ Immunix™ platform, which enables precision medicine in acute care. Immunix™ facilitates the development and validation of new precision solutions, such as AI biomarkers, and their real-time implementation. Over a decade of collaboration with more than ten U.S. partner hospitals, Prenosis used Immunix™ to build a proprietary biobank and dataset of over 113,000 blood samples from more than 28,000 patients. Prenosis merges biological data extracted from these samples with clinical information from Electronic Medical Records, creating the world’s largest biological-clinical dataset for acute care patients with suspected serious infections. This dataset enables the development of AI algorithms to detect rapid immune responses and recommend personalized therapies in real time in hospitals and emergency departments.

About Prenosis

Prenosis Inc. is an artificial intelligence company pioneering precision medicine in acute care.  We believe healthcare should be tailored to individual biology. Our data-driven approach to fast-moving biology in acute care is ushering in a new era of precision medicine. Powered by our Immunix™ precision medicine platform, we generate proprietary biological insights that drive the development of precision products and enable real-time delivery of optimal therapy. With Immunix™, we created and validated the first FDA-authorized AI biomarker for sepsis, the Sepsis ImmunoScore™.

For more information, visit: www.prenosis.com

1 Disclosure: Shapiro holds private equity in and consults for Prenosis.

View original content to download multimedia:https://www.prnewswire.com/news-releases/study-published-in-the-new-england-journal-of-medicine-ai-concludes-that-the-sepsis-immunoscore-the-first-fda-authorized-ai-tool-for-sepsis-has-both-significant-diagnostic-and-predictive-power-302321806.html

SOURCE Prenosis

Related Topics:
Continue Reading
Click to comment

Leave a Reply

Your email address will not be published. Required fields are marked *

Technology

Thinkpal learning tablet from Think Academy wins TechRadar Pro Picks and Trusted Reviews Best in Show awards at CES 2025

Published

4 minutes ago

on

January 11, 2025

By

LAS VEGAS, Jan. 11, 2025 /PRNewswire/ — Think Academy debuted its Thinkpal tablet at CES 2025 and has won a TechRadar Pro Picks and Trusted Reviews Best in Show awards for this innovative new product.

Both awards are given to innovative products and solutions at CES that stand out from a packed crowd. Think Academy President, Alex Peng, was presented the awards at CES, noting the awards were given to Thinkpal because it is both a wholly unique product in the education technology market and also provides such value to parents and educators.

Designed to transform the way kids learn, explore, and thrive in an ever-evolving world, the Thinkpal is powered by cutting-edge AI that serves as a guide and tutor for young learners. With significant learning loss experienced in recent years, families and educators have faced unprecedented challenges as test scores in reading and math have seen steady declines. Parents have expressed their struggles in reigniting their children’s passion for learning, while educators grapple with the complexities of bridging diverse learning gaps.

To meet these challenges, the Thinkpal tablet offers a tailored, AI-powered solution that provides step-by-step writing guidance and real-time math support, making learning more intuitive and enjoyable.

Alex Peng introduced several key features of the Thinkpal during a press event. He showed the audience how Thinkpal’s “GeniusTutor,” an AI-powered system that transforms learning into an interactive and engaging experience, is the heart of this product’s features. Built on the Microsoft Azure OpenAI GPT-4o model, GeniusTutor provides real-time guidance and feedback, empowering students to:

Conquer complex math problems through logic-driven, step-by-step explanationsMaster writing with interactive prompts and instant feedback that build confidence and creativityEnhance vocabulary and reading skills with innovative tools like “Point-and-Discover,” where children can point to words in a physical book, and the tablet’s camera instantly provides explanations, along with guided reading exercises

Adding a touch of fun and companionship, “Thinkie,” an advanced AI-powered learning companion, engages children through voice-based natural language interactions. Thinkie chats, answers questions, and fosters curiosity, making the learning process enjoyable and dynamic.

With an extensive library of ebooks, gamified coursework, and compatibility with popular applications like Google Classroom, the Thinkpal Tablet is a versatile tool for modern families. The 11-inch TÜV Rheinland-certified eye-care screen also safeguards children’s vision during extended use, while the optional keyboard transforms the tablet into a Chromebook-like device, enhancing productivity and usability.

“Our mission is to provide every child with a personalized, world-class tutor that inspires confidence and a lifelong love for learning”, noted Alex Peng during a media interview Q&A. “We’re honored that TechRadar and Trusted Reviews recognize the potential of the Thinkpal to improve learning through advanced and accessible technology.”

The Thinkpal Tablet will be available for $249 ($339 including keyboard) at shop.thethinkacademy.com. Pre-orders open today.

About Think Academy

Think Academy, a subsidiary of TAL Education Group (NYSE: TAL), has been at the forefront of education innovation for over two decades. Serving more than 5 million K-12 students across 10+ countries, Think Academy is dedicated to creating fair and comprehensive educational opportunities. By integrating advanced technology with expert curriculum design, Think Academy is shaping the future of learning to be more accessible, engaging, and impactful.

For media inquiries, contact:
Cecilia Qian
cecilia@impact5r.com

View original content to download multimedia:https://www.prnewswire.com/news-releases/thinkpal-learning-tablet-from-think-academy-wins-techradar-pro-picks-and-trusted-reviews-best-in-show-awards-at-ces-2025-302348472.html

SOURCE Think Academy

Continue Reading

Technology

MLVision M5 Unveiled at CES 2025: Pioneering Innovation in Wearable Technology with the World’s Lightest AI-Powered AR Glasses

Published

4 minutes ago

on

January 11, 2025

By

LAS VEGAS, Jan. 11, 2025 /PRNewswire/ — At CES 2025, MLVision has officially launched its groundbreaking MLVision M5, setting a new global standard for wearable technology. Weighing a mere 25.8 grams, the MLVision M5 is the world’s lightest AI-powered AR glasses. The device combines cutting-edge artificial intelligence, precision engineering, and a commitment to privacy and accessibility.

“MLVision M5 is more than just a wearable device; it represents a significant breakthrough in both weight and product design,” said CEO Zhaoen Dai. “Our goal is to create smart AR glasses that feel effortless to wear, leveraging cutting-edge AR display technology and advanced AI models to genuinely help users work and live more efficiently and conveniently.”

Crafted with aviation-grade titanium and ultra-lightweight floating plastic, this device achieves an unprecedented balance between durability and comfort. Weighing only 25.8g, 40% less than traditional AR glasses, it ensures an effortless, all-day wearing experience that feels almost weightless. The ergonomic design caters to users’ needs, making it a perfect companion for both work and leisure.

This device introduces an industry-first modular design, setting a new benchmark for adaptability in AR glasses. This innovation allows users to seamlessly transition between an all-in-one configuration and a clip-on style, accommodating diverse preferences and use cases. For nearsighted users, the M5 eliminates the need for custom prescription lenses—a common limitation in traditional AR glasses. Instead, it can be conveniently clipped onto existing prescription glasses, offering unmatched practicality and cost savings. This thoughtful modularity not only enhances accessibility but also positions the MLVision M5 as a versatile solution for a broad spectrum of users.

One of MLVision M5’s standout features is its immersive visual projection system, which offers an 86-inch private virtual screen. Powered by MLVision’s proprietary Hummingbird Micro-LED light engine and advanced nano-scale diffraction waveguide technology, the glasses create a secure and private viewing experience, ideal for reading confidential documents or browsing personal files. To prioritize eye health, the device utilizes soft green light with a projection distance of 4 meters, reducing strain during extended use.

The MLVision M5 is also equipped with the AIOS platform, delivering unparalleled AI-driven capabilities to enhance user productivity and accessibility. With intelligent tools like document summarization, real-time translation in seven languages, and interactive AI chat for setting reminders and brainstorming ideas, the device seamlessly integrates into the modern workflow. Additionally, its innovative Care Mode provides real-time audio transcription, enabling a more inclusive experience for users with hearing impairments.

The MLVision M5 excels as a navigation powerhouse, offering intuitive, real-time directions to guide users seamlessly through various environments. Whether exploring a new city, finding the fastest route to your destination, or navigating while riding a bike, the M5 ensures you always stay on the right path with ease and confidence.

The MLVision M5 will launch in China at the end of January 2025. Pricing and pre-order details will be announced in the coming weeks.

MLVision, a global innovator in wearable technology, continues to push the boundaries of what is possible by merging innovation, style, and functionality. With the launch of MLVision M5, the company reinforces its commitment to accessibility, sustainability, and creating cutting-edge solutions that redefine how technology is integrated into everyday life.

View original content to download multimedia:https://www.prnewswire.com/news-releases/mlvision-m5-unveiled-at-ces-2025-pioneering-innovation-in-wearable-technology-with-the-worlds-lightest-ai-powered-ar-glasses-302348534.html

SOURCE MLVision

Continue Reading

Technology

Brandivio Launches Advanced Retail Allocation Platform for Inventory Excellence

Published

5 minutes ago

on

January 11, 2025

By

Brandivio’s inventory optimization solutions empower footwear and apparel brands and retailers to buy smarter, allocate & replenish faster, and meet demand with precision.

NEW YORK, Jan. 11, 2025 /PRNewswire-PRWeb/ — Brandivio, a new generation inventory excellence platform for apparel and footwear retailers, announces its expansion into North America, in conjunction with the National Retail Federation’s (NRF) Big Show in New York City.

The Brandivio platform addresses the unique needs of the retail allocation market, ensuring apparel and footwear retailers have innovative tools to grow and thrive,” said Keith Whaley, SVP of Retail Solutions at Brandivio.

Brandivio, already supporting top-tier brands in EMEA, is built by seasoned retail experts to solve critical inventory challenges in fashion and footwear.

Leveraging machine learning, real-time demand signals, and automation, the Brandivio platform optimizes the distribution of products across a retailer’s stores and e-commerce channels ensuring the right products are in the right places at the right times, ultimately improving sales and margin performance, customer satisfaction, and inventory efficiency.

Key Features of Brandivio –

Advanced Demand Sensing: Predict future demand for short lifecycle products using machine learning native algorithms incorporating hyper-local external datasets to map powerful demand drivers.Dynamic Inventory Allocation: Adjust inventory in real time at the SKU/location level based on in-season trends to reduce stockouts and overstock situations.Real-Time Analytics: Drive test and learn strategies, optimize assortment in-season and connect functional teams across the organization with actionable insights for rapid response to market trends.Automation: Reduce up to 80% of existing manual planning efforts and redirect planner focus towards even greater efficiencies.Ease of Use: Intuitive workflows ensure rapid adoption without extensive training.

“Retailers can no longer rely on outdated tools or seasonal strategies,” said James Townsend, CEO of Brandivio.

“Brandivio democratizes retail data science, enabling brands to level the playing field, compete effectively, and maximize profits in today’s fast-paced market.”

This launch underscores Brandivio’s mission to support U.S. retailers facing tighter margins and increasing competition. “Our platform addresses the unique needs of this market, ensuring retailers have the tools to grow and thrive,” added Keith Whaley, SVP of Retail Solutions.

Contact us for a demo at info@brandivio.com or visit Brandivio.com for more.

Media Contact

Keith Whaley, Brandivio, Inc., 1 9494453183, keith.whaley@brandivio.com, https://brandivio.com

View original content to download multimedia:https://www.prweb.com/releases/brandivio-launches-advanced-retail-allocation-platform-for-inventory-excellence-302345595.html

SOURCE Brandivio, Inc.

Continue Reading

Trending