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Nano Positioning Systems Market to Grow by USD 183.95 Million (2024-2028) as AI Powers Market Evolution, Nanotechnology Applications Boost Revenue – Technavio

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NEW YORK, Nov. 20, 2024 /PRNewswire/ — Report on how AI is driving market transformation – The global nano positioning systems market size is estimated to grow by USD 183.95 million from 2024-2028, according to Technavio. The market is estimated to grow at a CAGR of 13.48% during the forecast period. Wide application of nanotechnology is driving market growth, with a trend towards growing focus on development of hybrid nano positioning systems. However, high sensitivity of nano positioning systems to environmental conditions poses a challenge.Key market players include Aerotech Inc., Allied Motion Technologies Inc., CEDRAT TECHNOLOGIES SA, Dynamic Structures and Materials LLC, Grayfield Optical Inc., Harbin Core Tomorrow Science and Technology Co. Ltd., ISP System, Mad City Labs Inc., MICRONIX USA, MKS Instruments Inc., Novanta Inc., OME Technology Co. Ltd., OWIS GmbH, Physik Instrumente GmbH and Co. KG, Piezosystem Jena GmbH, Prior Scientific Instruments Ltd., Pro Lite Technology Ltd., SmarAct GmbH, Thorlabs Inc., and WITTENSTEIN SE.

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Forecast period

2024-2028

Base Year

2023

Historic Data

2018 – 2022

Segment Covered

Application (Optics, Automotive, Industrial, and Others), Type (Capacitive sensor, Piezoresistive sensor, and Piezoelectric sensor), and Geography (North America, Europe, APAC, Middle East and Africa, and South America)

Region Covered

North America, Europe, APAC, Middle East and Africa, and South America

Key companies profiled

Aerotech Inc., Allied Motion Technologies Inc., CEDRAT TECHNOLOGIES SA, Dynamic Structures and Materials LLC, Grayfield Optical Inc., Harbin Core Tomorrow Science and Technology Co. Ltd., ISP System, Mad City Labs Inc., MICRONIX USA, MKS Instruments Inc., Novanta Inc., OME Technology Co. Ltd., OWIS GmbH, Physik Instrumente GmbH and Co. KG, Piezosystem Jena GmbH, Prior Scientific Instruments Ltd., Pro Lite Technology Ltd., SmarAct GmbH, Thorlabs Inc., and WITTENSTEIN SE

Key Market Trends Fueling Growth

The nanopositioning systems industry is experiencing significant growth due to increasing demands for devices with higher accuracy and speed. Optics, microscopy, semiconductor manufacturing, and photonics packaging are key applications driving this trend. Unique sensor arrangements offer error-free measurement in three coordinate axes, providing nano-metric precision. Advanced positioning systems, such as MEMS and capacitive sensors, use ceramic technology for miniaturization. Piezoelectric actuators and sensors, including strain gauge and piezoresistive, enable mechanical integration and force generation with lower energy consumption. Nanotechnology and biotechnology applications, including QUT, robot vision, service robots, autonomous vehicle systems, biomedical engineering, healthcare, quantum computing, nanoscale electronics, and tools and systems, are expanding the industry’s scope. Optical scanning, bio-nanotechnology, and optical alignment are essential in the aerospace and automotive sectors for tight tolerances in microelectronics, microchips, and optical devices. Diagnostic and therapeutic purposes, biological samples, nanometer-scale accuracy, and rapid response times are critical in imaging, communication, and sensing applications. High-tech companies and startups are investing in nanopositioning systems to meet the demands of various industries. However, trade disputes and shutting down of some manufacturers may impact the market. Sub-nanometer resolution, optical components like lenses, mirrors, prisms, and fibers, and advanced control algorithms are essential for future developments. 

Nano positioning systems have long been recognized for their high accuracy in various industries. However, these traditional systems encounter limitations in terms of speed, adaptability, and versatility for diverse applications. To address these challenges, hybrid nano positioning systems have emerged as a promising solution. These systems integrate multiple positioning technologies, combining the strengths of traditional macro-positioning systems with advanced nano positioning techniques. Macro-positioning systems offer coarse positioning and general movement, while nano positioning elements provide fine-tuned control for high precision at the nanoscale. An illustrative example is the integration of piezoelectric actuators with servo motors, which enhances performance across a broader range of applications. This hybrid approach enables improved speed, adaptability, and versatility for nano positioning systems. 

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Market Challenges

The nanopositioning systems industry faces challenges in achieving high accuracy and speed in devices using optics for microscopy, semiconductor manufacturing, photonics packaging, and biotechnology applications. Unique sensor arrangements are essential for error-free measurement along three coordinate axes, requiring nanometer-level precision. Trade disputes and shutting down of factories pose risks, but increasing application scope in advanced positioning systems drives growth. MEMS technologies using capacitive sensors, ceramic technology, and miniaturization are key trends. Piezoelectric actuators, sensors like strain gauge and piezoresistive sensors, mechanical integration, and force generation are important for nanotechnology and biotechnology applications. Lowered energy consumption is a priority. Nanopositioning systems are used in quantum computing, nanoscale electronics, tools and systems, optical scanning, bio-nanotechnology, optical alignment, aerospace, automotive, quality control, and more. Applications include diagnostic and therapeutic purposes, drug delivery, imaging agents, personalized medicine, medical devices, and more. High-tech companies and startups are investing in piezoelectric technology for sub-nanometer resolution and rapid response times. Optical technologies, imaging, communication, sensing applications, and nanometer-level accuracy are key areas of focus. Optical components like lenses, mirrors, prisms, and fibers are essential.Nano positioning systems are essential for manipulating objects at the nanometer level. These systems are highly sensitive to environmental conditions, particularly temperature and humidity. Temperature fluctuations can cause material properties and dimensions to change, impacting the stability and calibration of the system. Thermal expansion and contraction must be carefully managed to minimize errors. Similarly, humidity can affect the performance of nano positioning systems by altering their electrical properties or causing condensation. Maintaining a stable and controlled environment is crucial for ensuring the accuracy and precision of these advanced systems.

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Segment Overview 

This nano positioning systems market report extensively covers market segmentation by

Application 1.1 Optics1.2 Automotive1.3 Industrial1.4 OthersType 2.1 Capacitive sensor2.2 Piezoresistive sensor2.3 Piezoelectric sensorGeography 3.1 North America3.2 Europe3.3 APAC3.4 Middle East and Africa3.5 South America

1.1 Optics- The global fiber optics market is experiencing significant growth due to the increasing number of data centers, rising Internet traffic, and growing disposable income of consumers. This trend is driving the demand for advanced fiber-optic components, leading to an increased need for precise measurement using nano positioning systems. Major players in the fiber-optics industry, such as SANWA Denki Kogyo Co., Ltd. And Cisco Systems, Inc., are expanding their presence through mergers and acquisitions (M&A), further fueling the demand for nano positioning systems. The commercialization of 5G technology and subsequent data growth, as well as substantial investments in fiber-optic infrastructure, are additional factors contributing to the market’s expansion. For instance, NTT DATA Corporation’s new data center campus in Maharashtra, India, and Peninsula Fiber Network, LLC and 123NET’s partnership for fiber-optic network investments in Michigan, USA, highlight the market’s growth potential. These developments underscore the importance of nano positioning systems in the fiber-optics industry, ensuring accurate component manufacturing and assembly for the expanding global market.

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Research Analysis

Nano positioning systems are advanced technology solutions that offer precise and high-speed motion control in three coordinate axes. These systems utilize unique sensor arrangements and control algorithms to ensure error-free measurement and alignment of devices, such as microscopy systems, semiconductor manufacturing equipment, photonics packaging systems, and optical devices. The accuracy and speed of these systems are crucial in various industries, including biotechnology, robot vision, service robots, autonomous vehicle systems, biomedical engineering, and the aerospace and automotive sectors. In microelectronics, nano positioning systems enable the manufacturing of microchips and optical devices with tight tolerances, ensuring optimal optical performance for diagnostic applications. Piezo actuators and optical alignment techniques are commonly used in these systems to achieve sub-nanometer positioning accuracy.

Market Research Overview

Nano positioning systems are advanced technology devices that offer nanometer-level accuracy and rapid response times. They utilize unique sensor arrangements and error-free measurement capabilities to control movement along three coordinate axes. These systems are finding increasing application scope in various industries, including semiconductor manufacturing, photonics packaging, and microscopy. Optics play a crucial role in these systems, with applications ranging from optical scanning and alignment to optical performance enhancement in microelectronics and optical devices. The nanopositioning systems industry is witnessing significant advancements, with the development of MEMS (Micro-Electro-Mechanical Systems) technologies using capacitive sensors, piezoelectric actuators, and strain gauge sensors. Ceramic technology and miniaturization are also key trends, enabling lower energy consumption and mechanical integration. Nanotechnology and biotechnology applications, such as QUT (Quartz Ultrasonic Transducers) and robot vision, are also driving growth. Trade disputes and shutting down of factories pose challenges, but the industry is expected to continue expanding due to the growing demand for advanced positioning systems in sectors like healthcare, quantum computing, nanoscale electronics, and the aerospace and automotive industries. Nano positioning systems are essential for achieving tight tolerances and ensuring quality control in various applications, including microchips, nanoparticles, drug delivery, and imaging agents for biomedical applications. Personalized medicine and medical devices markets are also significant consumers of these systems. Piezoelectric technology offers sub-nanometer resolution and rapid response times, making it a popular choice for many applications. Optical components, such as lenses, mirrors, prisms, and fibers, are also important in these systems, as they play a crucial role in achieving optimal optical performance. High-tech companies and startups are investing heavily in research and development to push the boundaries of nanopositioning technology and create innovative solutions for various industries.

Table of Contents:

1 Executive Summary
2 Market Landscape
3 Market Sizing
4 Historic Market Size
5 Five Forces Analysis
6 Market Segmentation

ApplicationOpticsAutomotiveIndustrialOthersTypeCapacitive SensorPiezoresistive SensorPiezoelectric SensorGeographyNorth AmericaEuropeAPACMiddle East And AfricaSouth America

7 Customer Landscape
8 Geographic Landscape
9 Drivers, Challenges, and Trends
10 Company Landscape
11 Company Analysis
12 Appendix

About Technavio

Technavio is a leading global technology research and advisory company. Their research and analysis focuses on emerging market trends and provides actionable insights to help businesses identify market opportunities and develop effective strategies to optimize their market positions.

With over 500 specialized analysts, Technavio’s report library consists of more than 17,000 reports and counting, covering 800 technologies, spanning across 50 countries. Their client base consists of enterprises of all sizes, including more than 100 Fortune 500 companies. This growing client base relies on Technavio’s comprehensive coverage, extensive research, and actionable market insights to identify opportunities in existing and potential markets and assess their competitive positions within changing market scenarios.

Contacts

Technavio Research
Jesse Maida
Media & Marketing Executive
US: +1 844 364 1100
UK: +44 203 893 3200
Email: media@technavio.com
Website: www.technavio.com/

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Safeguard Global Pay to Feature New Product Capabilities in Partnership with Workday at Marquee EMEA Event

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Safeguard Global Pay will serve as a key partner for joint go-to-market activities at Workday Rising EMEA

AMSTERDAM, Nov. 21, 2024 /PRNewswire/ — Safeguard Global Pay, a leading global managed payroll provider, today announced it will host an exclusive demo of Workday’s Global Payroll Connect at next month’s Workday Rising EMEA event. The innovations were born from Race to Rising, a competition hosted by Workday, Inc. (NASDAQ: WDAY), which Safeguard won earlier this year.

“As Workday’s original global payroll partner, we’re passionate about global pay and we’ve been doing it longer than anyone,” said Tristan Woods, Chief Product Officer at Safeguard Global Pay. “It is our mission to serve as a payroll provider that manages, accelerates and scales payroll for organizations globally, through a community of local payroll experts, partners, and a single, agile platform. And that’s why we’re positioned to offer the very best solutions in the global payroll market.”

In May 2024, Workday announced its Race to Rising competition, aimed at unifying the experience between Workday and global payroll providers. Safeguard Global Pay competed alongside six other invited brands and was given eight weeks to build and implement next-gen integrations for Workday’s Global Payroll Connect – a unified global payroll solution that can seamlessly connect with payroll providers to deliver an end-to-end global payroll experience. Only two of the seven global payroll providers made it to the finish line, with Safeguard Global Pay emerging as one of the winners

Safeguard Global Pay is bringing these innovations to life at Workday Rising EMEA. Attendees are invited to an exclusive demo of Workday’s Global Payroll Connect, presented by Woods, on Tuesday, December 10th, at 17:30 at Safeguard Global Pay’s booth #206.

Workday’s API-driven integrations were all designed to provide greater connectivity between Workday and payroll systems, increasing efficiency and eliminating reliance on manual spreadsheets. Together, the integrations revolutionize payroll processes by delivering more automation, easier access to accurate data, and less maintenance. 

This announcement comes on the heels of Safeguard Global Pay being named a Platinum Innovation Partner with Workday earlier this year. As the first global payroll partner to attain Platinum Innovation Partner, Safeguard Global Pay seamlessly connects with Workday and standardizes payroll data and processes, streamlining and unifying everything into one platform and one process for customers in over 170 countries.

To learn more, visit safeguardglobal.com/pay.

About Safeguard Global Pay
Safeguard Global Pay manages, accelerates and scales payroll for organizations around the world. We deliver a unified client experience through a global community of local payroll experts, partners, and an agile platform, for accurate, compliant, complete and timely pay with every cycle. As a leading global managed payroll provider, we offer certified, bi-directional integrations with Workday for a consistent and optimized experience. Seamlessly integrate HR and payroll data around the world, gain comprehensive insights to labor costs, and ensure maximum engagement with Workday.

Media Contact
Lindsay Mahaney
safeguardglobal@meetkickstand.com

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U.S. MORTGAGE LENDING RISES IN Q3 2024 AMID REFINANCING SURGE, BUT REMAINS BELOW HISTORIC HIGHS

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Residential Lending Grows Just 2 Percent Even as Rates Keep Declining; Refinance and Home-Equity Deals Rise While Purchase Loans Decrease

IRVINE, Calif., Nov. 21, 2024 /PRNewswire/ — ATTOM, a leading curator of land, property data, and real estate analytics, today released its third-quarter 2024 U.S. Residential Property Mortgage Origination Report, which shows that 1.67 million mortgages secured by residential property (1 to 4 units) were issued in the United States during the third quarter. That led to modest quarterly and annual increases of 1.9 percent.

The growth marked the second straight quarterly gain – a pattern not seen for more than three years. But even as home-mortgage rates dropped close to 6 percent for a 30-year fixed loan by the end of Q3 2024, the increase in business for lenders was far below a spike during the Spring of 2024 and still left total mortgages off by nearly two-thirds from a high point hit in 2021.

The latest trend resulted from improvements in refinance and home-equity lending as opposed to more buyers taking out loans. Mortgage rollovers increased 6.9 percent quarterly, to about 588,000, while home-equity packages went up 2.3 percent, to roughly 297,000.

Those improvements more than made up for a 1.7 percent decrease in purchase loans, to 782,000, as the annual peak home-buying season wound down and supplies of properties for sale remained tight.

Measured monetarily, lenders issued roughly $550 billion worth of residential mortgages in the third quarter of 2024. That was up 2.9 percent from the second quarter of 2024 and 6.6 percent from the third quarter of last year.

The differing pattern of increases among various loan types slightly raised the portion of all residential mortgages represented by refinance and home-equity credit lines, while lowering the purchase component. Still, purchase loans remained the most common form of mortgages around the U.S. during the third quarter, comprising almost half.

“Mortgage lending rose again in the third quarter, but at a far slower pace than during the Spring of this year when activity spiked nearly 25 percent,” said Rob Barber, CEO at ATTOM. “The latest increase, small as it was, likely came mainly from homeowners trading higher-rate loans they got in 2021 and 2022 for cheaper mortgages resulting from declining mortgage rates. But it looked like the third-quarter rate dip wasn’t as helpful for purchase lending as buyers kept facing elevated prices and low supplies of properties for sale.”

The latest lending trends reflected another round of mixed forces affecting home sales and the cost of borrowing. Average 30-year mortgage rates dropped a full percentage point in the third quarter, the kind of decline that can save homeowners thousands of dollars a year on all kinds of loans. But the number of homes for sale remained at some of the lowest levels in the past decade, which continues putting a damper on the market, and purchase loans.

Total lending up again but still far below peaks
Banks and other lenders issued a total of 1,666,816 residential mortgages in the third quarter of 2024, up from 1,636,073 in the second quarter of 2024 and from 1,635,056 in the third quarter of 2023.

Total activity rose for the second quarter in a row – a pattern that hadn’t happened since early in 2021. But the latest figure still remained 60 percent behind a recent high point of 4,165,695 hit in the first quarter of 2021 when average 30-year mortgages rate hovered around 3 percent.

A total of $553.1 billion was lent to homeowners and buyers in the third quarter of this year. That was up from $537.5 billion in the prior quarter and from $518.6 billion in the third quarter of 2023, although still less than half the recent peak of $1.3 trillion in 2021.

Overall lending activity also rose quarterly and annually in a majority of metropolitan areas around the U.S. with enough data to analyze. The total increased from the second quarter to the third quarter of this year in 125, or 60.4 percent, of the 207 metropolitan statistical areas that had a population of 200,000 or more and at least 1,000 total residential mortgages issued from July through September of 2024.

The largest quarterly increases came in Anchorage, AK (total lending up 78.6 percent from the second quarter of 2024 to the third quarter of 2024); Yuma, AZ (up 33.3 percent); Ann Arbor, MI (up 33 percent); Huntington, WV (up 21 percent) and Trenton, NJ (up 20.5 percent).

Metro areas with a population of least 1 million that had the biggest increases in total loans from the second to the third quarter of 2024 were Rochester, NY (up 20.1 percent); Detroit, MI (up 14.7 percent); Grand Rapids, MI (up 13.5 percent); San Diego, CA (up 13.2 percent) and Hartford, CT (up 12.7 percent).

Metro areas with enough data to analyze where lending went down the most quarterly were Boulder, CO (down 44.3 percent); St. Louis, MO (down 36.5 percent); Jackson, MS (down 25.2 percent); Myrtle Beach, SC (down 20.4 percent) and Springfield, MO (down 19.4 percent)

Measured annually, the largest increases in total lending among metro areas with a population of at least 1 million were in Orlando, FL (total lending up 29.3 percent from the third quarter of 2023 to the third quarter of 2024); San Jose, CA (up 28.7 percent); San Diego, CA (up 27.9 percent); Honolulu, HI (up 25.9 percent) and Tucson, AZ (up 17.6 percent).

Purchase mortgages decline amid tight market but still make up almost 50 percent of all lending
While overall third-quarter lending activity increased, the number of mortgages issued to home buyers was down both quarterly and annually. The count of purchase loans remained only half of where it stood in 2021.

The third-quarter total of 782,220 was off from 796,046 in the second quarter of 2024, 814,610 in the third quarter of 2023 and 1.6 million in mid-2021.

The latest dollar volume of purchase loans, $306.6 billion, was 2.5 percent less than the $314.3 billion second-quarter level, although still up 0.8 percent from $304.1 billion a year earlier. It sat 43 percent below the 2021 peak

Residential purchase-mortgage originations decreased quarterly in 55.1 percent of the 207 metro areas in the report and annually in 56 percent of those markets.

The largest quarterly decreases were in Boulder, CO (purchase loans down 50.1 percent from the second quarter of 2024 to the third quarter of 2024); St. Louis, MO (down 42.4 percent); Springfield, MO (down 25.7 percent); Savannah, GA (down 25 percent) and Lake Havasu City, AZ (down 23.1 percent).

Including St. Louis, the biggest quarterly decreases in metro areas with a population of at least 1 million in the third quarter of 2024 came in Austin, TX (down 20.6 percent); San Francisco, CA (down 17.7 percent); Tucson, AZ (down 16.8 percent) and Atlanta, GA (down 15 percent).

The top annual decreases in purchase lending in metro areas with a population of at least 1 million were in St. Louis, MO (down 50.3 percent from the third quarter of 2023 to the third quarter of 2024); Austin, TX (down 48.2 percent); Houston, TX (down 29.7 percent); Dallas, TX (down 22.5 percent) and Raleigh, NC (down 21.3 percent).

Refinance mortgages up to highest level in two years
As interest rates declined during the third quarter of this year, lenders issued 587,691 residential refinance mortgages. That was up from 549,812 in the second quarter of 2024 and 539,738 a year earlier.

The most recent figure stood out as the most since the third quarter of 2022. It represented the latest in a series of increases following a spike in interest rates in 2021 and 2022 that caused refinance lending to plummet more than 80 percent.

The $191.1 billion dollar volume of refinance packages in the third quarter of 2024 was up 13.5 percent from $168.5 billion in the prior quarter and up 16.1 percent, from $164.7 billion, in the third quarter of 2023.

Refinancing activity increased quarterly in 75.8 percent and annually in 75.4 percent of the metro areas around the U.S. with enough data to analyze.

The largest quarterly increases were in Anchorage, AK (refinance loans up 59.1 percent from the second to the third quarter of 2024); Ann Arbor, MI (up 46.9 percent); Vallejo, CA (up 46.7 percent); Colorado Springs, CO (up 42.4 percent) and Charlottesville, VA (up 41.7 percent).

Metro areas with a population of least 1 million where refinance activity increased most quarterly were San Jose, CA (up 28.7 percent); Milwaukee, WI (up 27.4 percent); San Diego, CA (up 27.2 percent); Richmond, VA (up 24.4 percent) and Los Angeles, CA (up 24 percent).

Metro areas with a population of least 1 million and the largest year-over-year increases in the number of refinance loans were San Diego, CA (up 62.5 percent from the third quarter of 2023 to the third quarter of 2024); San Jose, CA (up 59.1 percent); Los Angeles, CA (up 40.3 percent); Seattle, WA (up 39.8 percent) and Las Vegas, NV (up 39.3 percent).

Refinance packages comprised 35.3 percent of all loan originations in the third quarter of 2024. That was up from 33.6 percent in the prior quarter but far less than the 65.8 percent portion in early 2021.

HELOC lending up quarterly and annually
Home-equity lines of credit (HELOCs) also increased, to 296,905 in the latest three-month period. That was up from 290,215 in the second quarter of 2024 and 280,708 in the third quarter of last year. The improvement continued to reverse losses sustained from 2022 into early 2024.

The $55.4 billion volume of HELOC loans in the third quarter of 2024 was up from $54.7 billion in the prior quarter and from the $49.8 billion lent in the third quarter of last year.

HELOCs comprised 17.8 percent of all loans in the most recent quarter. That was almost the same as the 17.7 percent portion in the second quarter of 2024 but still almost four times the level recorded in early 2021.

HELOC mortgage originations increased from the second quarter to the third quarter of 2024 in 63.1 percent of the metro areas analyzed. The largest quarterly increases in metro areas with a population of at least 1 million were in Fresno, CA (up 33.4 percent); Hartford, CT (up 29.5 percent); Louisville, KY (up 22.9 percent); San Antonio, TX (up 20.8 percent) and San Jose, CA (up 20.6 percent).

FHA mortgage level holds steady while VA loan portion rises
Lenders issued 229,196 mortgages backed by the Federal Housing Administration (FHA) during the third quarter, or 13.8 percent of all residential property loans. That was unchanged from the second quarter of this year after 10 consecutive quarterly increases but was down from 15.1 percent in the third quarter of 2023.

Residential loans backed by the U.S. Department of Veterans Affairs (VA) totaled 97,669, or 5.9 percent of all residential property loans originated in the third quarter of 2024. That was up from 5 percent in the previous quarter and 4.8 percent in the third quarter of 2023.

Report methodology
ATTOM analyzed recorded mortgage and deed of trust data for single-family homes, condos, town homes and multi-family properties of two to four units for this report. Each recorded mortgage or deed of trust was counted as a separate loan origination. Dollar volume was calculated by multiplying the total number of loan originations by the average loan amount for those loan originations.

About ATTOM 
ATTOM provides premium property data and analytics that power a myriad of solutions that improve transparency, innovation, digitization and efficiency in a data-driven economy. ATTOM multi-sources property tax, deed, mortgage, foreclosure, environmental risk, natural hazard, and neighborhood data for more than 155 million U.S. residential and commercial properties covering 99 percent of the nation’s population. A rigorous data management process involving more than 20 steps validates, standardizes, and enhances the real estate data collected by ATTOM, assigning each property record with a persistent, unique ID — the ATTOM ID. The 30TB ATTOM Data Warehouse fuels innovation in many industries including mortgage, real estate, insurance, marketing, government and more through flexible data delivery solutions that include ATTOM Cloudbulk file licensesproperty data APIsreal estate market trendsproperty navigator and more. Also, introducing our newest innovative solution, making property data more readily accessible and optimized for AI applications – AI-Ready Solutions.

Media Contact:
Megan Hunt
Megan.hunt@attomdata.com

Data and Report Licensing:
949.502.8313
datareports@attomdata.com

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DP Technology and Lepu Biopharma Announce Milestone Collaboration: Leveraging Advanced Computational Methods to Accelerate ADC Drug Innovation

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This partnership has effectively integrated DP’s ADC Linker-Payload design platform with Lepu’s ADC technology development platform, capitalizing on their respective strengths. The overall optimization of the ADC drug has been achieved in a relatively short time.

BEIJING, Nov. 20, 2024 /PRNewswire/ — Lepu Biopharma Co., Ltd. (Lepu Biopharma) and Beijing DP Tech Co., Ltd. (DP Technology) have recently announced a significant milestone in their Antibody-Drug Conjugate (ADC) drug collaboration. This partnership has effectively integrated DP’s ADC Linker-Payload design platform with Lepu’s ADC technology development platform, capitalizing on their respective strengths. The overall optimization of the ADC drug has been achieved in a relatively short time. This project has reached an important milestone, further validating the approach of accelerating ADC innovative drug development through computational design. Moving forward, both parties will continue to deepen their R&D collaboration in this field, jointly committed to promoting the continuous optimization and advancement of innovative drug development processes.

The ADC Linker Payload design platform, meticulously crafted by DP Technology, utilizes “RiDYMO®”, an AI-for-Science driven hit discovery platform. Furthermore, “AI + first principles” based computational methods are employed to predict linker cleavage sites and ensure the correct payload release, achieving outstanding cell-killing and bystander effects. Additionally, the designed antibody-drug conjugates (ADCs) maintain excellent hydrophilicity and plasma stability. Leveraging Lepu’s mature and complete ADC development system, candidates developed by the new ADC platform have demonstrated significant efficacy in CDX models targeting multiple targets. This project has been successfully validated in animal models and is currently advancing the candidate ADC to the clinical stage.

Lei Fang, Ph.D., Vice President of Lepu Biopharma and CEO of CtM Bio Co., Ltd., expressed high appreciation for this cooperation: “Introducing advanced computational methods to solve scientific problems and jointly pioneering breakthrough explorations is our goal in the ADC project collaboration. As a leader in ‘AI for Science’, DP Technology has played a crucial role in this project with its newly developed ADC design platform. By integrating Lepu Biopharma’s advanced ADC development platform with AI-driven design, we proposed novel perspectives on ADC development while significantly expediting the process. By complementing each other’s strengths, we jointly provide new inspiration and ideas for innovative ADC drug design.”

Weijie Sun, CEO of DP Technology, expressed great anticipation for future collaboration: “Lepu Biopharma, as an innovative biopharmaceutical company focused on cancer treatment, particularly in the areas of targeted therapy and immunotherapy, has extensive experience and a long-standing track record in developing innovative ADC drugs. We firmly believe that our close cooperation will significantly accelerate the design and development of ADC drugs, and we are optimistic about the potential to develop innovative, highly effective, and differentiated new ADC therapies. I am eagerly anticipating the ongoing and deepened collaboration between both companies in the field of pharmaceutical innovation!”

Concerning the various demands from industry partners in the ADC field, DP Technology’s ADC platform has successfully empowered various scenarios and projects. For instance, it utilizes AI combined with first-principles calculations to predict linker cleavage sites and improve attachment stability. By integrating pre-trained models with fine-tuning strategies and expert insights, the platform can predict and modify physicochemical properties such as payload efflux and bystander effects. Additionally, there is ongoing exploration and collaboration in the overall evaluation of properties like aggregation effects in ADCs.

About Lepu Biopharma

Lepu Biopharma Co., Ltd. is an innovation-driven biopharmaceutical company focusing on oncology therapeutics, in particular, targeted therapy and oncology immunotherapy, with a strong China foundation and global vision. We are dedicated to developing innovative ADCs through an advanced ADC technology development platform. We aim to develop more optimal and innovative drugs to better serve the unmet medical needs of cancer patients. We endeavor to continuously develop a market-differentiating pipeline by combining in-house research and development as well as strategic collaborations, strengthen our in-house manufacturing capabilities and commercialize our pipeline products in China through dedicated sales and marketing forces, and internationally via partnerships. We have an integrated end-to-end capability across drug discovery, clinical development, CMC and GMP-compliant manufacturing, encompassing critical functions of the biopharmaceutical value chain, and are building dedicated sales and marketing forces.

About DP Technology

At DP Technology, we’re at the forefront of integrating artificial intelligence into scientific research and industrial R&D. Our “AI for Science” initiative is redefining how we tackle complex scientific challenges, making groundbreaking discoveries more accessible and actionable.

We’ve developed the “DP Particle Universe,” a suite of advanced pre-trained models that seamlessly connect cutting-edge research with real-world industrial applications. Our software suite includes: Bohrium® Scientific Computing Space Station, Hermite® Computational Drug Design Platform, RiDYMO® Hit Discovery Platform, Piloteye® Battery Design Automation Platform. Together, these platforms form a robust foundation for industrial innovation and an open ecosystem for AI in science, fostering advancements in key areas such as drug discovery, energy, materials science and information technology.

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