Connect with us

Technology

Space-Based 3D Cell Culture Research Paves the Way for New Cancer Therapies

Published

on

ISS National Lab Helps Fuel the Development of Groundbreaking Treatment for All Types of Cancer and Beyond

KENNEDY SPACE CENTER, Fla., Oct. 28, 2024 /PRNewswire/ — In October, we think pink, and for a good reason—one out of every eight women will be diagnosed with breast cancer in their lifetime, and each year, 2 million women are given this frightening diagnosis. Biotechnology startup MicroQuin leveraged the International Space Station (ISS) National Laboratory to grow 3D breast and prostate cancer cell cultures to learn more about how these cancers develop and grow. However, the research team found something incredible that could lead to a way to treat not just breast and prostate cancers but all cancers.

Through MicroQuin’s ISS National Lab-sponsored research, the team identified microgravity-induced changes in cancer cell signaling that revealed something critical to cancer cell survival. Cancer cells’ survival depends on their ability to regulate changes in their intracellular environment (the environment within the cells). As part of MicroQuin’s research, the team crystallized a protein called TMBIM6 that plays a key role in regulating cells’ intracellular environment and determined its structure.

Based on this new knowledge, MicroQuin developed a small molecule therapeutic that binds to TMBIM6 and alters how cancer cells regulate intracellular environment changes, causing the cells to die. TMBIM6 is only activated in cancer cells, so the therapeutic does not harm healthy cells. When MicroQuin researchers tested the therapeutic in the lab, they found it worked for all types of cancer.

Even more incredible, MicroQuin discovered that the findings about intracellular environment regulation could apply to many other conditions like neurodegenerative diseases, traumatic brain injury, and even viral infection.

In a newly released article in Upward, official magazine of the ISS National Lab, MicroQuin founder and CEO Scott Robinson says, “What we’re seeing is that at the heart of every disease or injury, you have an intracellular environment change, and if you can alter how a disease changes the cell’s intracellular environment, you can either fully stop the disease or slow its progression.”

The idea that research on the space station, orbiting 250 miles above our planet, could impact your life may seem hard to imagine. But for Amelia Smith, ISS National Lab science communications manager, the value of MicroQuin’s space-based research hit close to home. In an Upward “View From the Cupola” feature, Smith shares her perspective on the company’s groundbreaking ISS cancer research and her own breast cancer diagnosis.

“Discoveries in space aren’t just achievements on a space station,” she says in the perspective piece, “they are breakthroughs that could lead to a world where families like mine are filled with hope instead of fear in the face of cancer and other devastating diseases.”

MicroQuin’s research was supported by the Technology in Space Prize, funded by the Center for the Advancement of Science in Space™ (CASIS®), which manages the ISS National Lab, and Boeing in partnership with the MassChallenge startup accelerator program.

To learn how MicroQuin’s ISS research led to a “massive paradigm shift” in how scientists think about cancer treatment, read the Upward feature “Orbital Oncology: 3D Cell Cultures in Space Reveal the Secret to Killing Cancer Cells on Earth.”

Download a high-resolution photo of NASA astronaut Christina Koch supporting the MicroQuin investigation while on the space station here.

About the International Space Station (ISS) National Laboratory:
The International Space Station (ISS) is a one-of-a-kind laboratory that enables research and technology development not possible on Earth. As a public service enterprise, the ISS National Laboratory® allows researchers to leverage this multiuser facility to improve quality of life on Earth, mature space-based business models, advance science literacy in the future workforce, and expand a sustainable and scalable market in low Earth orbit. Through this orbiting national laboratory, research resources on the ISS are available to support non-NASA science, technology, and education initiatives from U.S. government agencies, academic institutions, and the private sector. The Center for the Advancement of Science in Space™ (CASIS™) manages the ISS National Lab, under Cooperative Agreement with NASA, facilitating access to its permanent microgravity research environment, a powerful vantage point in low Earth orbit, and the extreme and varied conditions of space. To learn more about the ISS National Lab, visit our website.

As a 501(c)(3) nonprofit organization, CASIS accepts corporate and individual donations to help advance science in space for the benefit of humanity. For more information, visit our donations page.

Media Contact:

Patrick O’Neill

904-806-0035

PONeill@ISSNationalLab.org

 

International Space Station (ISS) National Laboratory

Managed by the Center for the Advancement of Science in Space, Inc. (CASIS)

6905 N. Wickham Rd., Suite 500, Melbourne, FL 32940 • 321.253.5101 • www.ISSNationalLab.org

 

View original content to download multimedia:https://www.prnewswire.com/news-releases/space-based-3d-cell-culture-research-paves-the-way-for-new-cancer-therapies-302288851.html

SOURCE International Space Station National Lab

Continue Reading
Click to comment

Leave a Reply

Your email address will not be published. Required fields are marked *

Technology

The Week in Canadian Press Releases: 10 Stories You Need to See

Published

on

By

A roundup of the most newsworthy press releases from Cision Distribution this week

TORONTO, Dec. 27, 2024 /CNW/ – With thousands of press releases published each week, it can be difficult to keep up with everything on Cision. To help journalists and consumers stay on top of the week’s most newsworthy and popular releases, here’s a recap of some major stories from the week that shouldn’t be missed.

The list below includes the headline (with a link to the full text) and an excerpt from each story. Click on the press release headlines to access accompanying multimedia assets that are available for download.

MNP WELCOMES 21 BDO CANADA OFFICES, PARTNERS, TEAMS, ACROSS FOUR PROVINCES 
MNP and BDO, two of Canada’s leading professional services firms, announced today that MNP will acquire a select number of BDO’s Canadian offices, partners and team members, effective December 31, 2024. In total, 21 BDO Canada offices, with more than 40 partners and 420 team members will join MNP. The transaction will include selected locations in B.C., Alberta, Ontario and P.E.I.; provinces where both firms have offices. A list of the selected offices can be found below. MNP’s business model is designed to support its clients, team members and communities with a locally focused approach. National Bank receives final approval to proceed with the acquisition of Canadian Western Bank
“This is a fantastic outcome for our clients, our teams and the communities in which we operate. We’re excited to join forces with National Bank to offer our clients access to a more comprehensive product and service platform on a national scale. We look forward to continuing to support our clients with the same highly personalized service and regional expertise we’ve always been known for,” said Chris Fowler, President and CEO of CWB. Following this last remaining approval, National Bank and CWB will work together to ensure a smooth transition to National Bank for CWB clients and employees, who will receive additional information shortly, as both banks work towards completing the transaction.BC Ferries Announces Discussions with Bondholders 
Following its conversations, BC Ferries has received feedback from such bondholders and is considering the launch of a formal consent and proxy solicitation to amend the MTI which would be conducted pursuant to the process required by the MTI.  It is also expected that if such a consent and proxy solicitation were to be launched, it would likely include the offering of a work consent fee in accordance with standard market practice for such transactions. This notice does not represent a notice of the launch of a consent solicitation, proxy solicitation or bondholder meeting and does not provide any assurance that such a process or transaction will be executed.Payfare Enters into Definitive Agreement to be Acquired by Fiserv 
“Our Board conducted a thorough strategic review process together with our financial advisors, having evaluated numerous acquisition, commercial partnership, and other opportunities, and concluded that the Transaction is in the best interests of the Company, its various stakeholders and its shareholders with certainty of value with an all-cash offer,” said Marco Margiotta, Payfare CEO, and Founding Partner. “This Transaction represents tangible recognition of the value and strength of what Payfare has built as we embark on this exciting new chapter.”UHN Announces Purchase of 522 University Avenue
University Health Network (UHN), Canada’s leading research hospital, is growing to meet the health care needs of the future. Today, UHN announced the purchase of 522 University Avenue, a 15-storey building located at the southwest corner of University Avenue and Elm Street in the heart of Toronto’s Discovery District. The newly acquired property will support the expansion of UHN programs in cancer care, research and education at UHN’s Princess Margaret Cancer Centre and Toronto General Hospital. The building will also serve as another important training ground for health care learners from UHN’s Michener Institute of Education and partner academic institutions.Tentative agreement reached between UCCO-SACC-CSN, the Treasury Board and Correctional Services Canada 
After a long and arduous bargaining round that has lasted for just over 2 years, the UCCO-SACC-CSN bargaining committee has managed to register some significant gains for the members it represents. Salary wise, the members of UCCO-SACC-CSN will receive a 15,73% over 4 years. Additionally, our members will be receiving a pensionable 6365$ yearly allowance beginning June 1st, 2025, and a prorated 6240$ allowance on the date of signature.  The total monetary package represents approximately a 23% monetary increase for our members working within the institution. Paladin Completes the Acquisition of Fission Uranium Corp. 
Paladin Energy Ltd (ASX: PDN) (OTCQX: PALAF) (“Paladin”) and Fission Uranium Corp. (TSX: FCU) (OTCQX: FCUUF) (FSE: 2FU) (“Fission”) are pleased to announce the successful completion of Paladin’s acquisition of all of the issued and outstanding shares of Fission (the “Fission Shares”) by way of a court-approved plan of arrangement under the Canada Business Corporations Act (“Arrangement”) pursuant to the terms of the arrangement agreement among Fission, Paladin, and 1000927136 Ontario Inc. (the “Purchaser”) dated June 24, 2024, as amended on July 25, 2024 and August 29, 2024.Ontario Teachers’ Makes Investment in Omega Healthcare and Joins Private Equity at Goldman Sachs Alternatives as Co-Lead Investor 
Ontario Teachers’ Pension Plan (“Ontario Teachers'”) makes investment in Omega Healthcare Management Services (“Omega” or “the Company”) and joins Private Equity at Goldman Sachs Alternatives as Co-Lead investors. Omega is a leading technology-enabled healthcare management solutions provider. Terms of the transaction were not disclosed. Omega Healthcare works with healthcare institutions to empower them to deliver exceptional care while enhancing financial performance. Omega aims to help its clients increase revenues, decrease costs, and improve the overall patient experience through their comprehensive portfolio of technology-enabled and clinically-led solutions.Vermilion Energy Inc. Announces Strategic Deep Basin Acquisition 
The Acquisition enhances depth and quality of Vermilion’s Deep Basin inventory and complements the Company’s high-growth, liquids-rich Montney asset. Vermilion’s Canadian liquids-rich gas assets, combined with over 100 mmcf/d of high-netback, low-decline European natural gas production provides the Company with a premium realized natural gas price. Vermilion is committed to strategically growing its international assets both organically, as demonstrated by recent successes in Germany and Croatia, and via acquisitions. EDC welcomes new President and CEO Alison Nankivell 
Ms. Nankivell has more than 25 years of experience in international investments and finance, strategic planning, and leading high performing teams through transformation, all of which will be invaluable as EDC continues evolving to meet Canadian businesses’ changing needs. She joins EDC from MaRS Discovery District, where she served as CEO. Prior to her role with MaRS, Ms. Nankivell held progressively senior investment and leadership roles at EDC and EDC’s sister financial crown corporation, BDC.

Read more of the latest releases from Cision, see our resources for journalists, and stay caught up on the top press releases by following @cnwnews.

About Cision Canada

Cision is a comprehensive communications platform enabling more than 100,000 public relations and marketing professionals around the world to understand, influence and amplify their stories. As the market leader, Cision enables the next generation of communication professionals to strategically operate in the modern media landscape where company success is directly impacted by public opinion. Cision has offices in 24 countries through the Americas, EMEA and APAC, and offers a suite of best-in-class solutions, including Newswire, Brandwatch, Cision Communications Cloud® and Cision Insights. To learn more, visit www.cision.ca and follow @CisionCA on Twitter.

SOURCE Cision Canada

Continue Reading

Technology

Fangzhou Inc. Honored as an “Outstanding Innovation Firm” by Yangcheng Evening News

Published

on

By

GUANGZHOU, China, Dec. 27, 2024 /PRNewswire/ — Fangzhou Inc. (“Fangzhou” or the “Company”) (06086.HK), a leader in Internet healthcare solutions, was honored as an “Outstanding Innovation Firm” at the “Precision Engineering: 2024 Technology Pioneers Gala” held by Yangcheng Evening News on December 13th. Fangzhou garnered recognition for its significant milestones in 2024, including a successful listing on the Main Board of the Hong Kong Stock Exchange, and its role in spearheading the ongoing digital transformation of China’s healthcare sector.

Dr. Xie Fangmin, founder, chairman, and CEO of Fangzhou, remarked, “We are thrilled to receive this award from Yangcheng Evening News as an ‘Outstanding Innovation Firm’. Adhering to our corporate mission of ‘Better Health for All’, we will continue to cultivate a bold vision for the future of the Internet healthcare sector.”

2024 has been a significant year in Fangzhou’s development journey. Following its IPO in July 2024, the Company received commendation from the Guangzhou Municipal People’s Government for its contributions in advancing the digital transformation of the healthcare industry and enhancing public health. In October, Fangzhou was featured on the 2024 Guangdong “AI Catalyst” Enterprise Billboard at the 2024 Guangdong-Hong Kong-Macao Greater Bay Area Artificial Intelligence Industry Conference. More recently, the Company launched its ” AI Agent Solution” in November 2024 in partnership with Tencent Healthcare and Baidu Health, providing more efficient access to healthcare information and analysis for both consumers and healthcare professionals.

About Fangzhou Inc.

Fangzhou Inc. (06086.HK) is China’s leading online chronic disease management platform. With 45.6 million registered users and 217,000 registered doctors on its platform (as of June 30, 2024), the Company provides tailored medical care and precision medicine for a growing population of chronic disease patients. For more details, visit https://investors.jianke.com.

About Yangcheng Evening News

Yangcheng Evening News, first published in October 1957, was among the first broadly distributed evening newspapers established after the founding of People’s Republic of China. Produced in Guangzhou as the flagship publication of the Yangcheng Evening News Group, the newspaper has built a strong reputation for its critical and independent perspective, delivering engaging news coverage on a variety of topics that resonate with people’s daily lives.

Media Contact

For further inquiries or interviews, please reach out to:
Xingwei Zhao Associate Director of Public Relations Email: pr@jianke.com 

Disclaimer: This press release contains forward-looking statements. Actual results may differ materially from those anticipated due to various factors. Readers are cautioned not to place undue reliance on these statements

View original content to download multimedia:https://www.prnewswire.com/news-releases/fangzhou-inc-honored-as-an-outstanding-innovation-firm-by-yangcheng-evening-news-302339558.html

SOURCE Fangzhou Inc.

Continue Reading

Technology

XCMG Launches Used Equipment Certification to Drive Sustainable Development in Construction Machinery

Published

on

By

XUZHOU, China, Dec. 27, 2024 /PRNewswire/ — XCMG Machinery (“XCMG”, SHE: 000425) has officially launched the XCMG Certified Used Equipment brand, marking a significant milestone in the development of its circular business. This initiative reflects XCMG’s commitment to addressing industry challenges, promoting green circular economy principles, and accelerating the transition toward sustainable development and carbon neutrality.

In recent years, China’s construction machinery industry has made remarkable strides. Leveraging its deep technological expertise, extensive manufacturing experience, and well-established brand influence, XCMG has established its official certified used equipment brand. This initiative aims to empower industry transformation, enhance the lifecycle value of signature equipment, and offer customers comprehensive quality and service guarantees across the value chain.

At the recent bauma China Exhibition, XCMG and Ritchie Bros. co-hosted a used equipment auction, showcasing over 300 fully inspected and refurbished units from 16 XCMG product categories, including cranes, excavators, mining equipment, compactors, loaders, concrete machinery, and piling equipment. These units were launched on the Ritchie Bros. website, symbolizing a new chapter in the used equipment market.

In line with its vision to become the world’s premier service brand, XCMG also introduced the XCMG TrueCare (“TrueCare”) service brand. TrueCare embodies XCMG’s unrelenting pursuit of integrated solutions, aligning with the Solid to Succeed brand philosophy. The service brand is designed to deliver cutting-edge innovations, stringent quality control, and efficient services, empowering customers to maintain a competitive edge in global markets.

“This initiative will extend the value chain, foster innovation, and elevate XCMG to new heights as a globally recognized brand,” said Liu Jiansen, vice president of XCMG.

The five core missions of XCMG TrueCare are:

Swift: A global service network ensures rapid response to customer needs to minimize downtime.Optimal: Integration of XCMG’s five advanced digital management systems delivers tailored solutions to enhance operational efficiency.Long-term: TCO service models, including extended warranties and certified pre-owned programs, provide full lifecycle care and build lasting customer relationships.Intelligent: Comprehensive smart solutions address customer-specific requirements through the integration of R&D, production, supply, sales, and service.Dedicated: A global call center and a professional team provide 24/7 support, ensuring efficient equipment operation and 100% customer satisfaction.

With these strategic advancements, XCMG is poised to redefine industry standards, driving the adoption of sustainable practices and reinforcing its leadership in the global construction machinery market.

Photo – https://mma.prnewswire.com/media/2588046/XCMG_Launches_Used_Equipment_Certification_Drive_Sustainable_Development_Construction_Machinery.jpg

View original content:https://www.prnewswire.co.uk/news-releases/xcmg-launches-used-equipment-certification-to-drive-sustainable-development-in-construction-machinery-302339562.html

Continue Reading

Trending