Connect with us

Technology

Vanderbilt University School of Medicine Basic Sciences Adds Carterra’s LSAXT Instrument to Speed Drug and Vaccine Research and Advance Patient Care

Published

on

The Center for Structural Biology in the School of Medicine Basic Sciences will be a hub of research innovation using Carterra’s platform in traditional and AI-driven workflows for characterizing both antibodies and other biomolecules

SALT LAKE CITY and NASHVILLE, Tenn. , Sept. 25, 2024 /PRNewswire/ — Carterra® Inc., the world leader in innovative technologies enabling high-throughput biology, and the Vanderbilt University School of Medicine Basic Sciences announced today the addition of the Carterra LSAXT label-free interaction analysis platform to the Center for Structural Biology (CSB). Vanderbilt and Vanderbilt University Medical Center researchers will be able to discover and characterize large molecules including antibodies.

“Many of our researchers are trying to identify antibodies that bind to a protein involved in health or disease,” said Borden Lacy, director of the CSB and Edward and Nancy Fody Chair in Pathology and professor of biochemistry and pathology, microbiology and immunology. “The ability to rapidly screen and quantify binding for large libraries of antibodies will shape the way molecular discovery moves forward at Vanderbilt. The work we spend months on will now be completed in a matter of days. It is incredibly exciting.” 

Carterra’s LSA platform was used by pharmaceutical giant Eli Lilly during the COVID-19 pandemic to find antibodies effective against SARS-CoV-2. Within 90 days of isolating antibodies from an early COVID-19 survivor, Lilly was in clinical trials with the world’s first COVID-19 therapeutic, the antibody Bamlanivimab.

BAM, as it became known, is the fastest drug ever discovered and saved countless lives.  The publication in Science describing the feat concluded, “The resulting speed at which this drug discovery and development effort progressed…is a testament to the advanced discovery and characterization platforms.”

Vanderbilt investigators will now be able to leverage the Carterra platform for a variety of research aims. 

Two projects that are getting early traction include:

Stephanie Wankwicz, assistant professor of molecular physiology and biophysics and a faculty affiliate of the Center for Applied AI in Protein Dynamics, is elucidating the role of entropy in substrate specificity and catalysis.  Wankowicz is planning to use Carterra’s platform to more quickly and efficiently analyze a large panel of peptide sequence variants against a kinase. Older methods are very low throughput and would require high concentrations of the protein/peptide solution.

Brian Wadzinski, associate professor of pharmacology, recently submitted a grant application to characterize pan- and phosphor-specific nanobodies for investigating MAPK and PP2A signalling. Affinity measurements for these large panels of nanobodies and high-resolution epitope binning can only be performed on Carterra’s platform.

The LSAXT instrument includes hardware and software features that build upon the capabilities of Carterra’s original and highly successful LSA instrument while maintaining its impressive throughput and sample efficiency. The LSA platform delivers 100 times the data in 10 percent of the time-to-answer and uses only 1 percent of the sample required by other label-free platforms.

Just last year, Vanderbilt launched the Center for Applied AI in Protein Dynamics which will also benefit from the addition of Carterra’s platform.  The LSA® is the only label-free biosensor that can generate enough data, quickly and efficiently, to train algorithms and learning models used to predict the affinity and epitope coverage of drug candidates. Pharmaceutical and biotech companies who have now moved to AI-driven drug discovery workflows have standardized on the LSA.

Vanderbilt has always led its peers in research innovation,” commented Tim Germann, Chief Commercial Officer at Carterra. “To enable the use of AI in antibody discovery and characterization by adding the LSAXT to its stable of technologies cements Vanderbilt’s position as the academic leader in this rapidly evolving research landscape.”

Since its launch in 2018, Carterra’s interaction analysis platform has penetrated 19 of the largest 20 pharmaceutical companies, major universities and vaccine makers, contract research organizations (CROs), and biotechs on four continents. Characterizing binding kinetics and epitope coverage of large numbers of antibodies in early research has been transformative. The LSA platform has been profiled in multiple Science, Nature, and Cell peer-reviewed papers.

Media Contact:
Cheri Salazar, Sr. Marketing Manager
Carterra, Inc.
(408) 594-9400
Csalazar@carterra-bio.com 

About Carterra, Inc.
Carterra® is privately held and is the leading provider of high-throughput technologies designed to accelerate and improve the discovery of novel therapeutic candidates. Carterra’s LSA® instrument, software, and consumables for biotherapeutic discovery and characterization deliver up to 100 times the throughput of existing platforms in 10% of the time while using only 1% of the sample required by other systems. The LSA combines patented microfluidics technology with real-time high-throughput Surface Plasmon Resonance (HT-SPR) and industry-leading data analysis and visualization software to revolutionize mAb screening. The new LSAXT provides enhanced optics to enable additional applications in biotherapeutic discovery and characterization. Carterra, Inc. is based in Salt Lake City, Utah, and has Customer Experience Centers in San Francisco, Salt Lake City, Boston, Manchester, England, and Munich, Germany. Carterra products are available in Asia-Pacific and Oceania through our exclusive distributor, Revvity. For additional information, please visit www.carterra-bio.com.

About the Vanderbilt Center for Structural Biology
The Vanderbilt Center for Structural Biology promotes the broad use of structural biology approaches in all life science research and provides resources for education and training in state-of-the-art technologies. Uniquely, the CSB merges applications of high resolution structural biology disciplines, X-ray crystallography, NMR spectroscopy, cryo-electron microscopy and computational biology, with the biophysical instrumentation needed to characterize biomolecular interactions. This strategy allows researchers to solve fundamental structural problems in medicine and biology. The CSB facilitates collaborations with investigators across a range of Departments in both the College of Arts and Science, the School of Medicine Basic Sciences, and the School of Medicine in Vanderbilt University Medical Center. The CSB is directed by Borden Lacy, Edward and Nancy Fody Chair in Pathology and professor of biochemistry and pathology, microbiology and immunology.

Photo – https://mma.prnewswire.com/media/2515106/Canterra_LSAXT_HT_SPR.jpg
Logo – https://mma.prnewswire.com/media/2491466/Carterra_Logo.jpg

View original content to download multimedia:https://www.prnewswire.com/news-releases/vanderbilt-university-school-of-medicine-basic-sciences-adds-carterras-lsaxt-instrument-to-speed-drug-and-vaccine-research-and-advance-patient-care-302258515.html

SOURCE Carterra

Continue Reading
Click to comment

Leave a Reply

Your email address will not be published. Required fields are marked *

Technology

Innatera Showcases Revolutionary Neuromorphic Processor Enabling Next-Generation Ambient Intelligence at CES 2025

Published

on

By

Delft University of Technology spin-off’s Spiking Neural Processor utilizes a proprietary analog-mixed signal computing architecture that harnesses spiking neural networks to deliver unprecedented, brain-inspired cognition performance within an ultra-low power envelope.

LAS VEGAS, Jan. 7, 2025 /PRNewswire/ — Innatera, the pioneer of groundbreaking ultra-low power neuromorphic processors, is showcasing its Spiking Neural Processor (SNP) that transforms the way battery-powered devices make sense of the physical world at CES 2025. Demonstrations will take place January 7-10 at the Venetian North Tower Suite #26-136.

“At this pivotal moment in computing, Innatera’s breakthrough Spiking Neural Processor delivers unmatched energy-efficient, brain-inspired cognition for sensors, unlocking the promise of ambient intelligence,” said Sumeet Kumar, CEO of Innatera. “This revolutionary processor provides an all-in-one solution that simplifies and optimizes sensor data processing at the edge.”

Innatera’s SNP combines a Spiking Neural Network (SNN) engine with a RISC-V processor core and other accelerators to deliver a complete solution with exceptional performance in energy-constrained environments. The single-chip solution brings intelligence closer to sensors, enabling next-generation AI and signal processing for applications in consumer electronics, smart homes, and industrial IoT, such as audio interfaces, touch-free interfaces, presence detection, activity recognition, and ECG recognition.

The SNP achieves high-performance pattern recognition at the sensor edge and enables real-time analysis of sensor data to detect and identify embedded patterns, with sub-milliwatt power dissipation and sub-millisecond latency.

Ambient Intelligence marks a major departure from computing technology as we know it, paving the way for a future where digital interactions are as natural as breathing.

At CES 2025, Innatera is demonstrating how the SNP can transform computing in several real-world applications:

Audio Scene Classification: Audio scene classification allows devices to be aware of the environment they operate in and use this information to adapt their operation. For example, in noise canceling headphones, this might mean adapting to the ambient noise profile of an airplane or a city bus.Robust Human Presence Sensing: The detection of human presence is important in a wide range of indoor and outdoor applications, such as security cameras, smart lighting, video doorbells and smart TVs. Using a radar sensor, this demo showcases always-on, privacy-preserving human presence detection with exceptional accuracy and power efficiency.Robust People Counting Using Far Infrared Sensors: Innatera will showcase how its SNP enables advanced people counting and human presence detection with passive infrared sensors. Infrared technology is a non-intrusive, low-light, and privacy-preserving method for people counting and human presence detection.

The company’s presence at CES 2025 follows a remarkable year of growth and development for the innovation-driven Delft University of Technology spin-off. Earlier this year, the company announced the oversubscription of a Series A $21-million funding round that is now accelerating the company’s development of neuromorphic processors.

For the press kit, click here. To schedule a meeting or learn more about Innatera’s technology, click here.

About Innatera
Born out of a decade of research on energy-efficient neuromorphic computing at the Delft University of Technology, Innatera is pioneering a new breed of Ambient Intelligent microprocessors that revolutionize sensors with brain-like thinking. Backed by leading European deep-tech VCs Matterwave Ventures, MIG Capital, InvestNL, the European Innovation Council, Delft Enterprises and Innavest, Innatera is on a mission to infuse a billion sensors with brain-like intelligence by 2030. Innatera envisions a future where electronic devices integrate seamlessly into everyday life, making the world around us smarter, safer, and cleaner for everyone.

Media Contact
Samantha Bryton
Griffin360
388426@email4pr.com
212-481-3456

View original content:https://www.prnewswire.com/news-releases/innatera-showcases-revolutionary-neuromorphic-processor-enabling-next-generation-ambient-intelligence-at-ces-2025-302344581.html

SOURCE Innatera

Continue Reading

Technology

ID.me Appoints Brian Robins and Bill Welch to Board of Directors

Published

on

By

MCLEAN, Va., Jan. 7, 2025 /PRNewswire/ — ID.me, the market-leading digital identity wallet, today announced the appointments of SaaS industry leaders Brian Robins and William “Bill” Welch as independent members to ID.me’s Board of Directors. Robins, Chief Financial Officer of GitLab Inc., and Welch, Chief Executive Officer of Sysdig, bring decades of experience in scaling high-growth public and private technology companies. Robins and Welch join ID.me amid significant momentum, as the company has seen revenue grow more than 370% from 2020 through 2023.

“Brian and Bill are exceptional leaders whose complementary experience will be invaluable as ID.me continues to grow,” said Blake Hall, Founder and CEO of ID.me. “Brian’s financial and strategic leadership and Bill’s expertise in cloud security will strengthen our efforts to keep Americans safe while transacting online.”

Brian Robins will serve as Chair of the ID.me Board’s Audit Committee. Currently serving as CFO of GitLab, the DevSecOps platform, Robins brings over 25 years of experience leading both private and public high-growth software companies. Robins is responsible for GitLab’s financial and business systems functions, including accounting, tax, treasury, corporate finance, and investor relations. Robins led GitLab’s IPO readiness effort and public offering. In addition, he has led and advised multibillion dollar technology companies through hyper growth, IPO readiness/listings, and capital markets transactions. Prior to GitLab, Robins served as CFO at Cylance (acquired by BlackBerry), AlienVault (acquired by AT&T), and Verisign. Robins has a proven track record of improving financial performance, increasing go to market productivity, and creating shareholder value. Robins currently serves as special advisor at Brighton Park Capital, and on the Advisory Council at ForgePoint Capital Cybersecurity, and also serves on the GitLab Foundation Board of Directors.

“I am honored to help ID.me make identity verification through use of its digital wallet simpler and more secure for millions of Americans, as well as many critical government agencies and companies,” said Robins. “I’m looking forward to contributing to ID.me’s next phase of growth and helping to ensure that no identity is left behind.”

Bill Welch will serve as Chair of the ID.me Board’s Compensation Committee and Member of the Audit Committee. As CEO of Sysdig, the leader in real-time cloud security, Welch drives the company’s vision to stop cloud attacks instantly with AI-powered Sysdig Sage™ and open source Falco, the standard for cloud threat detection. Welch is a Cybersecurity industry veteran, bringing over 30 years of extensive experience leading public and private software companies and operationalizing and scaling product development and innovation, customer experience, talent acquisition, and strategic alliances globally. Prior to joining Sysdig as CEO, Welch served as President and COO of Talkdesk, where he was responsible for advancing the company’s long-term vision and global go-to-market operations. Welch also previously served as COO of Zscaler, where he led Zscaler’s global sales, channel, operations, customer care, and strategy, culminating in an industry-leading initial public offering and a nearly $32 billion market capitalization today. Welch has held senior leadership roles at Duo Security, HP Americas Software and Symantec, and, while serving as President and COO of Duo, Welch helped secure a $2.35 billion merger transaction with Cisco. Welch currently serves on Sysdig’s Board of Directors.

“I have always believed that fostering a performance-driven culture with a strong focus on customer-centered decisions leads to success,” said Welch. “I’m excited to join a dynamic leadership team at ID.me as the company provides a growing number of Americans with a better, safer experience online.”

ID.me is proud to welcome both Brian and Bill to the Board while we continue driving towards a safer, simpler, and more convenient way to interact online.

About ID.me
ID.me is the next-generation digital identity wallet that simplifies how individuals securely prove their identity online. Consumers can verify their identity with ID.me once and seamlessly login across websites without having to create a new login and verify their identity again. Over 135 million users experience streamlined login and identity verification with ID.me at 19 federal agencies, 44 state government agencies, and 66 healthcare organizations. More than 600 consumer brands use ID.me to verify communities and user segments to honor service and build more authentic relationships. ID.me’s technology meets the federal standards for consumer authentication set by the Commerce Department and is approved as a NIST 800-63-3 IAL2 / AAL2 credential service provider by the Kantara Initiative. ID.me is committed to “No Identity Left Behind” to enable all people to have a secure digital identity. To learn more, visit https://network.id.me/.

View original content to download multimedia:https://www.prnewswire.com/news-releases/idme-appoints-brian-robins-and-bill-welch-to-board-of-directors-302344712.html

SOURCE ID.me, Inc.

Continue Reading

Technology

KYOCERA AVX EXHIBITS AT CES 2025

Published

on

By

KYOCERA AVX and Kyocera Corporation are showcasing an extensive selection of highly engineered component and device technologies designed to enable state-of-the-art innovations in the automotive, transportation, industrial automation, logistics, communications, and medical industries.

FOUNTAIN INN, S.C., Jan. 7, 2025 /PRNewswire/ — KYOCERA AVX, a leading global manufacturer of advanced electronic components engineered to accelerate technological innovation and build a better future, is co-exhibiting with its parent company, Kyocera Corporation, at CES 2025 in Las Vegas this week.

CES is widely renowned as one of the world’s foremost tech events and has earned a reputation for presenting the industry’s boldest breakthroughs, sharpest minds, and most impactful brands and uniting key stakeholders committed to pioneering the future and transforming how we live.

In light of this, KYOCERA AVX and Kyocera Corporation are showcasing an extensive range of highly engineered component and device technologies designed to enable state-of-the-art solutions to the world’s most pressing and pervasive challenges.

Kyocera Corporation is showcasing a number of new products and technologies optimized for next-generation, high-reliability automotive, transportation, industrial automation, logistics, communications, and medical applications, including:

A cutting-edge, High-Definition Aerial Display that uses curved mirrors and a variety of non-contact sensors to produce realistic, high-resolution floating images while minimizing physical space requirements and power consumption. CES attendees can experience the new display in a futuristic automotive navigation demonstration at the co-branded booth, #4816 in the Vehicle Tech and Advanced Mobility zone.A breakthrough AI-Based Depth Sensor that accurately measures challenging targets, including extremely small, shiny, and semi-transparent objects, with best-in-class resolution that’s 10 times more accurate than traditional monocular measurements and, in turn, helps users better contend with labor shortages and improve productivity. Ideal applications include helping robots sort tiny parts in industrial manufacturing operations, accurately measuring elements of the human body, identifying shiny metallic surgical instruments, and enabling the peripheral monitoring of transportation robots in logistics and retail operations.A groundbreaking new Underwater Wireless Optical Communication technology that delivers the world’s fastest underwater communication speeds — up to 2Gb/s — thanks to a combination of fast-response, semi-polar gallium nitride (GaN) lasers that enhance data communication capabilities by expanding optical bandwidth and unique beam shape propagation characteristics. In addition to being fast, this new optical communication technology is highly reliable and secure, capable of sending transmissions to specific receivers, and resistant to sunlight.A smart, contactless, Millimeter-Wave (mmWave) Sensing System that accurately detects even minute vibrations in vital sensing applications, including autonomous driving and health (e.g., heart rate) monitors.A mmWave Simultaneous Localization and Mapping (SLAM) technology designed to replace mechanical-based LiDAR with 4D imaging radar to enable safer, more accurate autonomous driving capabilities, even in bad weather conditions, while minimizing cost.The versatile new Camera-LiDAR Fusion Sensor — the world’s first LiDAR sensor equipped with an integrated camera, an optical axis, and a unique MEMS mirror that delivers the world’s highest resolution and durability and enables the real-time superimposition of camera image data and LiDAR distance data for advanced object recognition. Ideal applications include ADAS, ships, and heavy machinery.A new Bifocal Mirror that displays enlarged images in the distance, making it easier for farsighted drivers to adjust their focus and clearly see their surroundings, and leverages augmented reality (AR) technology to better support safe driving by instantly displaying information recognized by the rearview camera in the mirror.

KYOCERA AVX is showcasing a selection of advanced components designed to enable next-generation technologies in a number of different industries. Featured components on display at CES 2025 include:

Antennas optimized to facilitate wireless connectivity in a wide variety of applications extending throughout the automotive, industrial, IoT, consumer, medical, transportation, and networking industries, including high-reliability standard and ultra-small chip antennas rigorously tested to AEC-Q200 requirements, such as the A-Series all-in-one (LTE, GNSS, and NTN) embedded automotive broadband antennas and 2.4GHz automotive corner chip antennas.Multilayer ceramic capacitors (MLCC) that exhibit low parasitics, excellent EMI filtering capabilities, high capacitance values, and various voltage ratings over a wide temperature range and are available in chip, leaded, and stacked configurations in addition to unique geometries.The industry’s widest range of high-reliability tantalum capacitors, which includes the smallest case size, highest temperature, and lowest DCL MnO2 solid tantalum technologies available on the market.An award-winning portfolio of conductive, low-profile, lead- and halogen-free solid electrolytic polymer capacitors that exhibit excellent stability, high capacitance, low-ESR performance, and a benign failure mode under recommended use conditions — including the smallest, highest-voltage, and highest reliability polymer capacitors available on the market.Aluminum electrolytic chip capacitors that deliver high-CV, high endurance, and very low ESR performance in smaller packages than competing can-type aluminum capacitors and specialized conductive polymer and hybrid electrolytic versions that also exhibit higher tolerance for ripple currents, inrush currents, and high temperatures than standard versions.Low-, medium-, and high-power dry and oil-impregnated film capacitors based on polyester and polypropylene dielectrics that exhibit controlled self-healing capabilities, are engineered for power electronics applications rated for 75V to 100kV, and are ideal for applications ranging from DC filtering and semiconductor protection and tuning to discharge and high energy storage.Supercapacitors or double-layer capacitors that provide a unique combination of characteristics, including very high pulse power and capacitance densities.An extensive portfolio of high-quality sensing and control products that make engines more efficient, emissions cleaner, and cars safer and are designed and produced according to the stringent requirements of the global automotive industry.A variety of unique connectors based on industry-proven contact technology and proven to provide robust, performance-driven solutions in a wide range of harsh-environment applications, including the industry’s first dual-entry card-edge connectors, which also feature the company’s lowest above-board height profile.

For more information about the future-forward component and device technologies that KYOCERA AVX and Kyocera Corporation are showcasing and demonstrating at CES 2025, please visit the links embedded here or visit them at Booth #4816 in the Vehicle Tech and Advanced Mobility Zone in the West Hall. For all other inquiries, please visit https://www.kyocera-avx.com/, email inquiry@kyocera-avx.com, follow them on LinkedInX (Twitter), and Instagram, like them on Facebook, call 864-967-2150, or write to One AVX Boulevard, Fountain Inn, S.C. 29644.

About KYOCERA
Kyocera Corporation (TOKYO:6971), the parent and global headquarters of the Kyocera Group, was founded in 1959 as a producer of fine ceramics (also known as “advanced ceramics”). By combining these engineered materials with metals and integrating them with other technologies, Kyocera has become a leading supplier of industrial and automotive components, semiconductor packages, electronic devices, smart energy systems, printers, copiers, and mobile phones. During the year ended March 31, 2024, the company’s consolidated sales revenue totaled 2.0 trillion yen (approx. US$13.3 billion). Kyocera is ranked #874 on Forbes magazine’s 2024 “Global 2000” list of the world’s largest publicly traded companies and has been named among “The World’s 100 Most Sustainably Managed Companies” by The Wall Street Journal.

About KYOCERA AVX
KYOCERA AVX is a leading global manufacturer of advanced electronic components engineered to accelerate technological innovation and build a better future. As a wholly owned subsidiary of Kyocera Corporation structured to capitalize on shared resources and technical expertise, KYOCERA AVX has an expansive global footprint comprised of several dozen research, development, and manufacturing facilities spanning more than 15 countries and staffed with talented personnel dedicated to innovation, component quality, customer service, and enabling a brighter future through technology. KYOCERA AVX designs, develops, manufactures, and supplies advanced capacitors, antennas, interconnects, circuit protection and timing devices, sensors, controls, filters, fuses, diodes, resistors, couplers, and inductors optimized for employment in the international 5G, IoT, aerospace, automotive, consumer electronics, industrial, medical, and military markets.

PR Image Download:
KAVX107 CES 2025 PR.jpg

View original content to download multimedia:https://www.prnewswire.com/news-releases/kyocera-avx-exhibits-at-ces-2025-302344375.html

SOURCE KYOCERA AVX

Continue Reading

Trending