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SIFI Receives European Commission Approval for AKANTIOR®

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AKANTIOR® (polihexanide) is the first and only approved drug for the treatment of acanthamoeba keratitis

CATANIA, Italy, Aug. 26, 2024 /PRNewswire/ — SIFI, a leading international ophthalmic company, today announced the European Commission has approved AKANTIOR® (polihexanide) for the treatment of acanthamoeba keratitis (AK) in adults and children from 12 years of age, confirming the orphan status of the product. AKANTIOR is the first and only approved therapy for people suffering from AK in Europe. 

AK is an ultra-rare, severe, progressive and sight threatening corneal infection characterized by intense pain and photophobia. AK is caused by a free-living amoeba, acanthamoeba, and primarily affects contact lens wearers.

“Today’s approval represents an important step towards delivering a new global standard of care for patients with AK and builds on 15 years of research and development,” said Fabrizio Chines, Chairman and CEO of SIFI. “For the first time in Europe AK patients have an approved therapy, marking a new era in the treatment of this disease, which may lead to blindness. AKANTIOR is the first and only approved medicine for AK, and our team is committed to developing polihexanide in other corneal infectious diseases, such as fungal keratitis, where we obtained orphan drug designation from the EMA and the FDA.”

“AKANTIOR, when used as monotherapy with the trial’s treatment protocol, achieves medical cure rates of over 86% and is set to become the standard of care for this severe and debilitating disease,” stated Professor John Dart, of Moorfields Eye Hospital and the UCL Institute of Ophthalmology, who was Principal Investigator of the Phase III ODAK trial. “After 15 years of research and effort development by SIFI, culminating in the pivotal Phase III clinical trial, polihexanide 0.08% has now been approved by the European Medicines Agency and European Commission as the first licensed treatment for acanthamoeba keratitis. This breakthrough offers significant improvement over current treatment options and has the potential to prevent blindness and save eyes. As the only approved therapy, it has been recommended for use with the detailed treatment delivery protocol used in the Phase 3 trial, which eliminates the need for the variable individualized treatment delivery currently used for patients, providing an effective standardized approach that can be followed by any clinician and which has been shown to be effective, not only in the Trial, but also in the current compassionate use program outside the more stringent Trial setting.”

“With the approval of AKANTIOR, AK patients (also known as AK Warriors) are now one step closer to having access to the best possible treatment in the EU. This milestone represents a significant step towards providing fair healthcare to all AK Warriors, giving them hope for a brighter future,” commented Juliette Vila Sinclair Spence, a rare disease patient advocate and the Chairwoman and Founder of AK Eye Foundation – the first global foundation dedicated exclusively to this condition.

In Europe, SIFI plans to initiate its first commercial launch in Germany during the last quarter this year, followed by additional markets based on local regulatory, healthcare technology assessment and reimbursement process timelines, including France, Italy, Romania, Spain, United Kingdom and Turkey addressing a total population of 430 million, and by Avanzanite, its commercial partner, in other European Countries addressing an additional population of 180 million. Based on scientific publications, the incidence of acanthamoeba keratitis is estimated at 1 to 4 patients per million inhabitants.

ABOUT AKANTIOR®: AKANTIOR (polihexanide 0.08%) is the first approved drug for the treatment of acanthamoeba keratitis in the world. It is an anti-amoebic polymer that acts on both the trophozoites and cysts of the protozoan acanthamoeba. It is formulated at a 0.8mg/ml (0.08%) concentration which makes it possible to administer as monotherapy eye drops in single-dose containers. The European Commission confirmed the orphan status of the product. The FDA granted SIFI Orphan Drug Designation for the treatment of acanthamoeba keratitis.

ABOUT Acanthamoeba Keratitis (AK): AK is an ultra-rare, acute, severe parasitic corneal infection caused by acanthamoeba, a free-living amoeba, although incidence of AK has been rapidly growing in recent years. AK is an ocular emergency and requires urgent treatment to save the eye. It can lead to poor vision, potential blindness, or even eye loss and often requires single or multiple corneal transplants. It affects people of all ages, most of whom are young or middle-aged soft contact lens wearers. Patients report unbearable pain and extreme light sensitivity and can rarely work or lead normal lives until symptoms resolve. 

ABOUT SIFI: SIFI is a leading international ophthalmic company, headquartered in Italy, featuring an integrated business model, from research and development to manufacturing and commercialization both in pharmaceutical and biomedical sectors. Since our foundation in 1935, our mission is to improve people’s lives through meaningful innovation in eye care. SIFI exports to more than 40 countries worldwide with a direct presence in major European markets, Mexico and, through joint ventures, in China and the United Arab Emirates. More information available at www.sifigroup.com.

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Reap Receives In-Principle Approval for Major Payment Institution License from Monetary Authority of Singapore

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SINGAPORE, Jan. 9, 2025 /PRNewswire/ — Reap, a leading payment technology provider, is thrilled to announce today that it has received an In-Principle Approval (IPA) from the Monetary Authority of Singapore (MAS) for its application of the Major Payment Institution (MPI) License for its Singapore entity, Reap Singapore.

Obtaining the IPA marks a significant milestone for Reap. Reap is committed to regulatory excellence while continuously enhancing its capabilities and presence in Singapore and the broader Asia Pacific region. While the IPA marks a critical step forward, Reap Singapore remains steadfast in meeting the required conditions for the MPI License. Reap is equally committed to dedicating the necessary resources to support and assist Reap Singapore in achieving this goal. Together, Reap and Reap Singapore will continue to refine its compliance standards and beyond, ensuring it delivers enhanced value and trusted solutions to Singapore and the broader APAC customers.

“At Reap, compliance has always been paramount, not only to safeguard our users but also as a fundamental pillar for growth. Receiving this IPA from the MAS, a globally renowned financial regulator, is incredibly motivating and will be a key driver of secure growth in the region. It fuels our enthusiasm to continue collaborating closely with regulatory bodies to shape a secure and efficient money movement across the region. Reap is also committed to building a strong payment service.” stated Kevin Kang, Co-Founder of Reap.

Singapore is integral to Reap’s mission of enhancing global money movement. Its high regulatory standards and commitment to foster sustainable innovation align seamlessly with Reap’s vision for the future of payment services. This alignment empowers Reap to drive secure and efficient financial flows while delivering exceptional value to its clients and partners.

About Reap

Reap group is a leading global payment technology provider that enables financial connectivity and access for businesses worldwide. By bridging disparate economies, merging technological divides, and connecting key financial players, we are transforming the financial landscape into a more interconnected and interoperable space for efficient money movement.

With corporate cards, payout solutions, and expense management tools, we streamline financial operations and empower businesses to scale. Our APIs enable businesses to embed finance into their own products and services, from issuing Visa cards to facilitating cross-border payments.

Founded in 2018 in Hong Kong, Reap has since expanded to a team of over 100 across the globe, including Singapore. Reap is supported by a strong network of investors, including Acorn Pacific Ventures, Arcadia Funds, HashKey Capital, Hustle Fund, Fresco Capital, Abacus Ventures, and Payment Asia.

For media enquiries, please contact:

Christine Cheuk
Marketing & PR Manager, Reap
christine@reap.global

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Mirae Asset Launches Global X G2 Tech ETF (3402): Investing in the Future of Technology

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HONG KONG, Jan. 10, 2025 /PRNewswire/ — Mirae Asset Global Investments (Hong Kong) Limited (referred to as “Mirae Asset”) today announced the launch of Global X G2 Tech ETF (3402), designed to track the Mirae Asset G2 Tech Index. This innovative ETF offers investors a unique opportunity to invest in leading technology companies from two of the world’s most influential economies: The United States and China.

The Global X G2 Tech ETF aims to capture growth and innovation across critical sectors, including semiconductors, artificial intelligence (AI), software, computer hardware, online retail, internet platforms, telecommunications, and technology products and services. With direct access to a diversified portfolio of 32 high-quality technology companies (as of Jan 10, 2025), investors can benefit from the rapid evolution of technology on a global scale. The ETF comes with an estimated annual ongoing charge of just 0.68%, making it an efficient way to gain exposure to the dynamic tech landscape.

Mr. Wanyoun CHO, Chief Executive Officer of Mirae Asset Global Investments (Hong Kong) Limited, stated, “As we launch the Global X G2 Tech ETF, we reaffirm our commitment to providing innovative investment solutions that empower our clients. This ETF reflects our dedication to harnessing growth opportunities in the technology sectors of the US and China. We believe in the transformative power of technology and are excited to offer investors direct access to a diversified portfolio of leading companies. Together, we are embarking on a journey to capture the future of innovation.”

For more information about the Global X G2 Tech ETF (3402), please visit the Global X ETFs website at www.globalxetfs.com.hk.

About Mirae Asset Global Investments Group

Mirae Asset Global Investments Group (the “group”) is an asset management organization with over US$272 billion in assets under management as of Sep 30, 2024[1]. The organization provides a diverse range of investment products including mutual funds, exchange traded funds (“ETFs”), and alternatives. Operating out of 25 offices worldwide, the group has a global team of more than 1,000 employees, including more than 200 investment professionals.

The group’s global ETF platform features a line-up of 601 ETFs that offer investors high quality and cost-efficient exposure to newly emerging investment themes and disruptive technologies in the global markets.[2] The group’s ETFs have combined assets under management of US$137 billion and are listed in Australia, Canada, Colombia, Europe, Hong Kong (SAR), India, Japan, Korea, Vietnam, the United Kingdom, and the United States.[3]

About Global X ETFs

Global X ETFs was founded in 2008. For more than a decade, our mission has been empowering investors with unexplored and intelligent solutions. Our product line-up features over 384 ETF strategies and over $92 billion in assets under management.[4] While we are distinguished for our Thematic Growth, Income, and International Access ETFs, we also offer Core, Commodity, and Alpha funds to suit a wide range of investment objectives. Global X is a member of Mirae Asset Financial Group, a global leader in financial services, has a presence in 19 global markets and the group’s managed assets exceed US$606 billion in assets under management worldwide.[5]

Mirae Asset Global Investments Hong Kong: https://www.am.miraeasset.com.hk/ 
Global X ETFs Hong Kong:  www.globalxetfs.com.hk 

Important Information

Global X G2 Tech ETF (3402)

Investors should not base investment decisions on this document alone. Please refer to the Prospectus for details including product features and the risk factors. Investment involves risks. Past performance is not indicative of future performance. There is no guarantee of the repayment of the principal. Investors should note:

Global X G2 Tech ETF (the “Fund”)’s investment objective is to provide investment results that, before fees and expenses, closely correspond to the performance of the Mirae Asset G2 Tech Index (the “Index”).The Fund will primarily use a full replication strategy through investing directly in constituent stocks of the Index in substantially the same weightings in which they are included in the Index (the “Replication Strategy”).Where the adoption of the Replication Strategy is not efficient or practicable or where the Manager considers appropriate in its absolute discretion, the Manager may pursue a representative sampling strategy and hold a representative sample of the constituent securities of the Index selected by the Manager using rule-based quantitative analytical models to derive a portfolio sample (the “Representative Sampling Strategy”).The Index is a new index. The Index has minimal operating history by which investors can evaluate its previous performance. There can be no assurance as to the performance of the Index. The Fund may be riskier than other exchange traded funds tracking more established indices with longer operating history.Due to the concentration of the Index in the technology sector, the performance of the Index may be more volatile when compared to other broad-based stock indices. The price volatility of the Fund may be greater than the price volatility of exchange traded funds tracking more broad-based indices.The Fund has high exposure to technology themes. The technology business is subject to complex laws and regulations including privacy, data protection, content regulation, intellectual property, competition, protection of minors, consumer protection and taxation. These laws and regulations are subject to change and uncertain interpretation, and could result in claims, changes to the business practices, monetary penalties, increased cost of operations or declines in user growth, user engagement or advertisement engagement, or otherwise harm the technology business. All these may have impact on the business and/or profitability of the technology companies that may be invested by the Fund and this may in turn affect the Net Asset Value of the Fund.The base currency of the Fund is USD but the trading currencies of the Fund are in HKD and USD. The Net Asset Value of the Fund and its performance may be affected unfavourably by fluctuations in the exchange rates between these currencies and the base currency and by changes in exchange rate controls.The borrower may fail to return the securities in a timely manner or at all. The Fund may as a result suffer from a loss or delay when recovering the securities lent out. This may restrict the Fund’s ability in meeting delivery or payment obligations from redemption requests. As part of the securities lending transactions, there is a risk of shortfall of collateral value due to inaccurate pricing of the securities lent or change of value of securities lent. This may cause significant losses to the Fund.The trading price of the Shares on the SEHK is driven by market factors such as the demand and supply of the Shares. Therefore, the Shares may trade at a substantial premium or discount to the Fund’s Net Asset Value.Payments of distributions out of capital or effectively out of capital amounts to a return or withdrawal of part of an investor’s original investment or from any capital gains attributable to that original investment. Any such distributions may result in an immediate reduction in the Net Asset Value per Share of the Fund and will reduce the capital available for future investment.

Disclaimer

This document is for Hong Kong investors only. This document is provided for information and illustrative purposes and is intended for your use only. It is not a solicitation, offer or recommendation to buy or sell any security or other financial instrument. The information contained in this document has been provided as a general market commentary only and does not constitute any form of regulated financial advice, legal, tax or other regulated services.

Certain of the statements contained in this document are statements of future expectations and other forward-looking statements. Views, opinions and estimates may change without notice and are based on a number of assumptions which may or may not eventuate or prove to be accurate. Actual results, performance or events may differ materially from those in such statements.

Investment involves risk. Past performance is not indicative of future performance. It cannot be guaranteed that the performance of the Funds will generate a return and there may be circumstances where no return is generated or the amount invested is lost. It may not be suitable for persons unfamiliar with the underlying securities or who are unwilling or unable to bear the risk of loss and ownership of such investment. Before making any investment decision, investors should read the Prospectus for details and the risk factors. Investors should ensure they fully understand the risks associated with the Funds and should also consider their own investment objective and risk tolerance level. Investors are advised to seek independent professional advice before making any investment.

Information and opinions presented in this document have been obtained or derived from sources which in the opinion of Mirae Asset Global Investments (Hong Kong) Limited (“MAGIHK”) are reliable, but we make no representation as to their accuracy or completeness. We accept no liability for a loss arising from the use of this document.

Products, services and information may not be available in your jurisdiction and may be offered by affiliates, subsidiaries and/or distributors of MAGIHK as stipulated by local laws and regulations. This document is not directed to any person in any jurisdiction where the availability of this document is prohibited. Persons in respect of whom such prohibitions apply or persons other than those specified above must not access this document. It is your responsibility to be aware of and to observe all applicable laws and regulations of any relevant jurisdiction. Please consult with your professional adviser for further information on the availability of products and services within your jurisdiction.

This document is issued by MAGIHK (Licensed by the Securities and Futures Commission for Types 1, 4 and 9 regulated activities under the Securities and Futures Ordinance). This document has not been reviewed by the Securities and Futures Commission or the applicable regulator in the jurisdiction in which this article is posted and no part of this publication may be reproduced in any form, or referred to in any other publication, without express written permission of MAGIHK.

Copyright © 2025 Mirae Asset Global Investments. All rights reserved.

[1] Source: Mirae Asset Global Investments, Sep 30, 2024.

[2] Source: Mirae Asset Global Investments,  Sep 30, 2024.

[3] Source: Mirae Asset Global Investments, Sep 30, 2024.

[4] Source: Mirae Asset Global Investments, Sep 30, 2024.

[5] Source: Mirae Asset Financial Group, Jun 30, 2024.

 

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SOURCE Mirae Asset Global Investments (Hong Kong) Limited

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Cohesity Expands Cyber Event Response Service with Incident Response Provider Partnerships, Fortifying Cyber Resilience

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Partnerships with Incident Response Leaders Palo Alto Networks Unit 42, Arctic Wolf, Sophos, Fenix24, and Semperis Speed Incident Recovery with Dedicated Expertise and Coordinated Support

SINGAPORE, Jan. 10, 2025 /PRNewswire/ — Cohesity, the leader in AI-powered data security, today announced it has expanded the Cohesity Cyber Event Response Team (CERT) service to include partnerships with leading incident response (IR) vendors. The Cohesity CERT team has years of specialized incident response expertise and has helped numerous customers respond and recover quickly from high-stakes security events since its formation in 2021. By partnering with leading IR vendors such as Palo Alto Networks Unit 42, Arctic Wolf, Sophos, Fenix24, and Semperis, Cohesity CERT augments the traditional IR process, infusing rich data and backup and recovery expertise, helping to speed investigations and enable customers to recover quicker from incidents.

Using native platform capabilities, Cohesity CERT can share a consolidated set of customer-approved operational data with its IR partners, including logs, reports, inventories, and more. This rich dataset, together with Cohesity CERT’s deep data security and recovery expertise, enhances the digital forensics, threat intelligence, and containment capabilities of IR partners, enabling them to perform more effective and efficient analysis of the cyber incident and quickly resolve issues while reducing business downtimes. Customers also have peace of mind their IR partner of choice can collaborate directly with Cohesity to streamline their cyber response and ensure they restore clean data faster.[1]

“With ransomware, data breaches, and other cyber threats becoming an unavoidable reality, organizations need the assurance that they can bounce back faster, stronger, and smarter,” said Sanjay Poonen, CEO, Cohesity. “Cohesity CERT is a natural extension of our mission to empower organizations with resilient, secure data management. We’re doubling our commitment to our customers by ensuring they have the expertise and tools to navigate and recover from cyber crises effectively. Cyber resilience is the cornerstone of modern cybersecurity, and we are committed to helping our customers achieve it.”

Cohesity CERT is available to all Cohesity customers as part of their existing subscription. Customers can benefit from:

Minimized Business Disruption and Financial Loss: As cyberattacks become more frequent and damaging, Cohesity aids customers in swiftly detecting, investigating, and recovering from incidents, preventing and minimizing extended operational disruptions.Comprehensive, Coordinated Response and Recovery: Working alongside its broad ecosystem of industry-leading IR partners, Cohesity has developed a methodology that utilizes native platform capabilities and integrations with its Data Security Alliance to provide greater insight into data breaches. This methodology includes a consolidated set of customer-approved operational data, including logs, reports, inventories, and more, which can be rapidly shared with approved parties, including an external incident response provider, to enable more effective and efficient analysis leading to safer and faster recovery after a destructive cyber attack.24/7 Availability and Multi-vendor Integrated Support: Cohesity CERT handles a wide range of incidents, from sophisticated ransomware and data breaches to targeted attacks, and assists customers whenever cyber incidents occur. Cohesity and its partners maintain communication throughout the response and recovery process, allowing for faster decision-making and a more agile response to cyberattacks.Specialized Expertise and Proactive Recommendations: Personnel from Cohesity CERT and its partners are seasoned cybersecurity experts with specialized knowledge in incident response, threat intelligence, and forensics, making them an invaluable resource during critical incidents. The service provides actionable recommendations and valuable expertise that help businesses strengthen their defenses over time, enabling customers to stay ahead of evolving cyber threats.

“Cybercriminals are increasingly emboldened by new technology, making cyberattacks more effective and efficient. Unit 42 provides customers with leading incident response expertise, threat intelligence and proactive services, enabling them to effectively address the most challenging threats. Through this new partnership, Cohesity will play a crucial role in expediting backup and business recovery processes of shared customers. This collaboration will greatly benefit our customers, ensuring a comprehensive approach to cybersecurity that enhances the overall investigation process for Unit 42,” said Sam Rubin, SVP of Consulting and Threat Intelligence, Unit 42 at Palo Alto Networks.

“Time and information are two of the most critical parts of incident response. The more information we have, the quicker we can return a customer to normal operations,” said Kerri Shafer-Page, Vice President, Incident Response, Arctic Wolf. “Cohesity’s quick response toolkit gives us access to all kinds of data that can enable a more comprehensive investigation and quicker recovery. Partnering with Cohesity CERT adds valuable expertise in backup and recovery and helps us ensure our joint customers are resilient no matter what attackers throw at them.”

“Your organization is only as safe as your backup controls are secure, redundant, immutable, and relevant to threat actor playbooks,” said John Anthony Smith, founder and chief security officer of Conversant Group. “However, incident response investigations can be complex and time-consuming. Therefore, our long-standing partnership with Cohesity CERT is highly beneficial to our joint customers because it adds valuable expertise in backup and recovery and helps us ensure resiliency no matter what attackers throw at them.”

“By partnering with Cohesity CERT, Sophos’ Incident Response (IR) team of experts who work 27/4 around the world identifying and neutralizing threats can jump right in to assess and react to active threats targeting Cohesity’s customers,” said Rob Harrison, senior vice president of Product Management for SecOps and Endpoint Security at Sophos. “This streamlined process is critical because the faster Sophos IR can get involved, the faster the team can disrupt and eject attackers before they exfiltrate data, carry out ransomware or other damaging activities. With this partnership, Sophos customers will also be referred to Cohesity’s quick response toolkit for comprehensive backup and recovery programs. This collaboration ensures our joint customers are more resilient and able to recover faster from cyberattacks.”

“Expanding our partnership with Cohesity will improve operational resilience for our joint customers and partners, by protecting the critical pathways that ransomware attackers use to compromise Microsoft Active Directory (AD) and Entra ID systems. In nearly all ransomware attacks, adversaries target AD or Entra ID as the key to the organization. Without sufficient backup and recovery solutions and regular continuity testing, disruptions of these identity systems can and do occur, costing organizations money and putting critical infrastructure at risk,” said Mickey Bresman, CEO, Semperis. “Semperis’ combined 150+ years of AD experience not only sets us apart in the hybrid identity system security market, it also enables us to protect top global organizations and rebuild compromised identity systems in hours rather than days, weeks, or months.”

“Enterprise security teams need all the help they can get. One third of enterprises have expressed that current staffing levels are inadequate for their organization’s challenges; the degrees of staff specialization have consistently increased. In lieu of additional staffing, enterprises are looking for vendors to provide value-added services that improve processes with their products.” – 451 Research, part of S&P Global Market Intelligence: 2023 VoTE Information Security Organizational Behavior & 2024 VoTE Information Security Budgets Study

For more information on Cohesity CERT, visit https://www.cohesity.com/cert/. In addition, join experts from Unit 42 at Palo Alto Networks, 451 Research, and Cohesity for a panel discussion entitled: “From Chaos to Collaboration: Partnerships Streamline Incident Response.” Visit https://www.cohesity.com/dm/from-chaos-to-collaboration/

About Cohesity

Cohesity is the leader in AI-powered data security. Over 12,000 enterprise customers, including over 85 of the Fortune 100 and nearly 70% of the Global 500, rely on Cohesity to strengthen their resilience while providing Gen AI insights into their vast amounts of data. Formed from the combination of Cohesity with Veritas’ enterprise data protection business, the company’s solutions secure and protect data on-premises, in the cloud, and at the edge. Backed by NVIDIA, IBM, HPE, Cisco, AWS, Google Cloud, and others, Cohesity is headquartered in San Jose, CA, with offices around the globe. To learn more, follow Cohesity on LinkedIn, X, and Facebook.

[1] For customer security, certain formalities and documentation may be required for advanced information sharing activities. Please contact Cohesity.

 

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