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Avirmax CMC Successfully Delivers First GMP Lot of AAV Vector Product for Clinical Trial Use

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HAYWARD, Calif., July 17, 2024 /PRNewswire/ — Avirmax CMC, a leader in the innovation and manufacture of adeno-associated virus (AAV) vector-mediated biotherapeutics, announces the successful delivery to its first client with Good Manufacturing Practice (GMP) lots of AAV vector product trial use.

Avirmax CMC Inc. Successfully Delivers GMP Lots of AAV Vector Products for Client’s Phase I/IIa Clinical Trial in the US

This milestone marks a significant achievement in Avirmax CMC’s mission to provide high-quality gene therapy solutions. The GMP-compliant AAV vectors were produced using Avirmax’s state-of-the-art VSaf™ rBV-Sf9 technology platform, which ensures high titers at extremely low empty capsid ratio, and enhanced expression of the gene of interest (GOI). The delivered vector product will play a crucial role in the upcoming clinical trial, aimed at treating ocular diseases.

“Our team at Avirmax CMC is thrilled to have reached this pivotal point in our journey. Delivering to our first customer with GMP lot of AAV vector product underscores our commitment to excellence and our capability to meet stringent regulatory standards and customer’s satisfaction,” said Dr. Shengjiang Shawn Liu, CEO & CSO of Avirmax CMC Inc. “We are dedicated to advancing gene therapy development for partners and making these innovative treatments accessible to patients in need.”

The GMP AAV product lots were produced, tested and packaged at Avirmax CMC’s cutting-edge facility in the City of Hayward, the heart of San Francisco Bay Area, which is equipped with single use technologies for scalable and robust manufacturing processes. The production process ensures that the vector products meet the highest standards of quality and safety required for clinical use.

The successful delivery of this GMP lot demonstrates Avirmax CMC’s readiness to support clinical trials and contribute to the development of effective gene therapies. The company’s focus on innovation and quality positions it as a key player in the biopharmaceutical industry.

About Avirmax CMC Inc.

Avirmax CMC is dedicated to the innovation, development, and manufacture of AAV vector-mediated biotherapeutics. Based in the San Francisco Bay Area, the company leverages its proprietary technologies to deliver safe, effective, and affordable gene therapy solutions. Avirmax CMC’s mission is to advance gene therapy and improve the lives of patients with ocular and CNS diseases. For more information about Avirmax CMC and its services, please visit Avirmax CMC’s website (https://www.avirmaxcmc.com/).

Contact

June Song, Associate Director for Operations
Email: business@avirmax.com
Tel: +1-510-641-0201

Address
25503 Whitesell Street
Hayward, CA 94545
USA

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SOURCE Avirmax

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Keynode Launches BTC Staking Service as Bitcoin Approaches $100K Milestone

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Keynode introduces a new BTC staking service, offering users an opportunity to earn rewards as Bitcoin nears the $100K milestone.

NEW YORK , Nov. 16, 2024 /PRNewswire-PRWeb/ — Keynode, a recognized leader in the crypto staking platform, is excited to introduce its latest BTC staking option, providing a unique opportunity for investors to participate in Bitcoin‘s growth journey. This new staking service aims to enable users to benefit from Bitcoin‘s market potential while contributing to broader adoption as Bitcoin targets the highly anticipated $100K threshold.

As one of the first platforms to offer Bitcoin staking in a straightforward, user-friendly manner, Keynode positions itself as a valuable tool for investors seeking to earn passive income through cryptocurrency. By offering a BTC staking option, Keynode combines the power of Bitcoin‘s market strength with the stability and growth potential of a staking-based approach. This program allows investors to stake their Bitcoin holdings and generate a steady yield, without needing to trade or sell assets.

Accessible Staking with Competitive Rewards

The BTC staking service on Keynode is designed to attract both new and experienced investors interested in diversifying their crypto portfolios. Keynode’s platform features an accessible structure with competitive staking rewards, making it appealing for a wide range of users. With staking periods and potential yield options crafted to meet different financial goals, Keynode ensures that users can tailor their participation according to their preferred level of commitment and growth expectation.

Driving Market Participation with Innovative Solutions

As Bitcoin continues to garner attention from both retail and institutional investors, reaching record highs has become a topic of market speculation. Keynode’s BTC staking program contributes to this momentum by offering secure and user-centric ways to support the Bitcoin ecosystem. As more individuals choose to stake BTC, the overall scarcity and demand for Bitcoin may be influenced, helping support a long-term vision of reaching new price heights.

“BTC staking represents a forward-looking approach in cryptocurrency investments,” said a Keynode spokesperson. “With this service, we are making it simpler for investors to stay invested in Bitcoin while also enjoying staking rewards, which aligns with Bitcoin‘s journey toward greater market adoption and potentially even the much-anticipated $100K mark.”

About Keynode

Keynode is a leader in crypto staking solutions, dedicated to offering accessible and reliable staking options for users across the globe. With a commitment to security and user-friendly features, Keynode continues to innovate in the crypto space, providing services that support investors in reaching their financial goals.

For more information on Keynode’s BTC staking service, visit Keynode.net or contact Keynode at (+1) 678-310-6834 or info@keynode.net.

Media Contact

Kiven Scott, Keynode, (+1) 678-310-6834, info@keynode.net, https://keynode.net/

View original content to download multimedia:https://www.prweb.com/releases/keynode-launches-btc-staking-service-as-bitcoin-approaches-100k-milestone-302307613.html

SOURCE Keynode

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Sustainable Infrastructure Holding Company (“SISCO”) Q3FY24 revenue (excluding accounting construction revenue) increases by 23.8% to 341.8 million

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Revenue grew by 23.8% compared to previous yearGross profit of SAR 179.8 million, a 21.7% increase compared to Q3FY23Adjusted EBITDA rose 29.5% to SAR 210.2 million

JEDDAH, Saudi Arabia, Nov. 16, 2024 /PRNewswire/ — Sustainable Infrastructure Holding Company (“SISCO”, “TADAWUL: 2190”), Saudi Arabia’s leading strategic investor in Ports & Logistics and Water Solutions has announced its financial results for the quarter ended 30 September 2024.

Revenues for the third quarter of 2024, excluding accounting construction revenue, grew by 23.8% compared to Q3FY23 to reach SAR 341.8 million. On a quarter-to-quarter basis, revenues grew by 13.0% compared to Q2FY24.

The third-quarter gross profit of SAR 179.8 million represents 14.7% quarter-on-quarter growth and 21.7% growth compared to Q3FY23. The gross profit margin for Q3FY24 was down 0.9% year-on-year, due to increased depreciation and direct costs, but was up 0.8% quarter-on-quarter, in line with expectations. Year-to-date saw gross profits increase by 13.8% to SAR 469.5 million.

Adjusted EBITDA growth rose 29.5% to SAR 210.2 million compared to Q3FY23, aligning SISCO with strategic goals. Quarter-on-quarter growth was 20.8%, with a year-to-date increase of 17.7% to SAR 543.8 million.

SISCO reports a strong recovery in the Red Sea Gateway Terminal from subdued Q3FY23 Port segment results due to the Red Sea situation. Port volume reached 828,868 TEUs in Q3FY24, returning to levels similar to Q4FY23.

Commenting on the results: Eng. Khalid Suleimani, Group CEO, SISCO said:

“I am pleased to report that SISCO has continued to demonstrate strong growth and operational performance in Q3FY24, with revenues improving by 23.8% compared to Q3FY23. Our Ports segment, which remains a key growth driver, saw a significant increase, leading to robust results despite the Red Sea challenges.

Net income remains strong, despite the one-off payment of SAR 25 million to Zakat. Another highlight of the quarter is the impressive recovery in the Red Sea Gateway Terminal, highlighting it’s resilience.

We are also excited to announce the Multi-Purpose Terminals (MPT) concession, which will allow us to expand operations across all non-containerised port facilities in the Red Sea Gateway Terminal. This strategic initiative positions SISCO to capture further growth opportunities domestically and internationally.

Looking ahead, we remain committed to executing our five-year strategy to double revenues by 2026 and continue delivering long-term value to our shareholders.”

View original content:https://www.prnewswire.co.uk/news-releases/sustainable-infrastructure-holding-company-sisco-q3fy24-revenue-excluding-accounting-construction-revenue-increases-by-23-8-to-341-8-million-302307352.html

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Carbon Mapper Achieves First Tanager-1 Methane Mitigation Success

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BAKU, Azerbaijan, Nov. 16, 2024 /PRNewswire/ — Carbon Mapper released over 300 methane and CO2 plume detections today— its first tranche of emissions data based on observations from the Tanager-1 satellite which was launched in August. Tanager-1 is built and operated by Planet Labs PBC and made possible by the Carbon Mapper Coalition, a philanthropically backed public-private partnership including Planet Labs and NASA’s Jet Propulsion Laboratory among others. This data offers granularity on sources of super-emitters around the world, driving direct actions to cut methane and carbon dioxide as proven by an early mitigation success story.

Tackling methane is a global priority. This mitigation success shows how remote sensing tech can be a game changer.

On Oct. 9, Tanager-1 detected a large plume of methane which Carbon Mapper determined was stemming from a gathering pipeline in the Texas Permian Basin. The team reported the leak to a state agency and the U.S. government, who subsequently notified the facility operator. The operator quickly responded and voluntarily conducted repairs, leading to meaningful emissions reduction. Follow up observations from Tanager-1 detected no plume, confirming the leak was successfully fixed.

Carbon Mapper’s preliminary emissions estimate of this leak is approximately 7,000 kilograms of methane per hour. Each hour it was emitting equaled the same CO2 emissions as driving 47 gas-powered cars for a year.

This first verified methane mitigation action adds to existing evidence that when decision makers are empowered with data on the exact sources of emissions, they can effectively prioritize actions that cut waste and eliminate methane. This mitigation is consistent with pilot airborne surveys Carbon Mapper has conducted in several U.S. states including California and Colorado. Through these pilots, Carbon Mapper has found that nearly half of super-emitting events flagged for state agencies and operators were previously unknown, and once identified, were voluntarily mitigated.

“Tackling methane quickly is a crucial global priority. This early mitigation success story shows that remote sensing technologies with unique capabilities like Tanager-1 can be a gamechanger in driving down emissions in the near-term,” said Carbon Mapper CEO Riley Duren.

To scale these local mitigation successes globally, Carbon Mapper is making new data from Tanager-1 publicly available on its data portal. These include detections of methane and CO2 in 34 countries across the oil and gas, waste, and agriculture sectors. This work is supported by the High Tide Foundation, Grantham Foundation for the Protection of the Environment, Bloomberg Philanthropies, Children’s Investment Fund Foundation, AKO Foundation, and Zegar Family Foundation, among others.

In the coming months, Carbon Mapper will continue to scale up observations and make methane and CO2 data routinely accessible to help decision makers fill gaps in their understanding of the exact sources of emissions and empower mitigation action at the source. These routine detections will be made publicly available for non-commercial use 30 days after collection. Together, with complementary satellite programs, like the Environmental Defense Fund’s MethaneSAT, Carbon Mapper will provide transparent data at different levels of granularity and ensure that the information gets into the right hands to catalyze faster and more effective emissions reductions.

Special Note to Reporters:
More information, including plume images and key data from Tanager-1, can be found in our press package here

About Carbon Mapper
Carbon Mapper is a nonprofit organization based in Pasadena, CA, with the mission to drive greenhouse gas emissions reductions by making methane and carbon dioxide data accessible and actionable. It focuses on filling gaps in the emerging ecosystem of methane and CO2 monitoring systems by delivering data at facility scale that is precise, timely, and accessible to empower decision making and direct mitigation action. The organization leads a public-private coalition that is developing and deploying a constellation of satellites capable of detecting, quantifying, and verifying methane emissions worldwide. Data from these satellites will offer the next major step in scaling up the organization’s robust data portal featuring thousands of direct observations of global methane and CO2 super-emitters. Learn more at carbonmapper.org, view data at data.carbonmapper.org, and follow us on X @carbonmapper.

View original content to download multimedia:https://www.prnewswire.com/news-releases/carbon-mapper-achieves-first-tanager-1-methane-mitigation-success-302307601.html

SOURCE Carbon Mapper Inc.

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