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ShiraTronics Unveils Data on their Neurostimulation System for Chronic Migraine

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MIAMI BEACH, Fla., July 16, 2024 /PRNewswire/ — ShiraTronics, a trailblazing clinical-stage neurostimulation company, proudly presented findings from its Australian Pilot Study, RELIEV-CM, at the American Society of Pain and Neuroscience (ASPN) Pain Conference. This pioneering study showcases the world’s first fully implantable neurostimulation system specifically engineered for chronic migraine.

Study participants have shown significant improvements in pain levels, migraine-days, and quality of life indicators

Promising Potential Migraine Treatment

The ASPN (American Society of Pain & Neuroscience) Conference, a premier gathering of the world’s leading experts in pain management and neuromodulation, was the perfect venue for ShiraTronics to present their Pilot Study results. The presentation highlighted ShiraTronics’ leadership in medical innovation and reinforced its commitment to addressing unmet patient needs in the realm of chronic migraine.

Dr. Steven Falowski, a renowned neurosurgeon from The Argires Marotti Neurological Associates Clinic in Lancaster, PA, and a leading expert in neurostimulation therapies, presented the compelling 12-week results. He emphasized the potential transformative impact of ShiraTronics’ system, which may offer a promising treatment for chronic migraine sufferers. ShiraTronics’ system is a minimally invasive, head-located device designed to provide continuous stimulation without interruption.

About the RELIEV-CM Pilot Study

The RELIEV-CM Pilot Study is evaluating the preliminary safety and performance of the ShiraTronics Migraine Therapy System. The system is designed to provide a discreet, continuous solution for chronic migraine sufferers. Chronic migraine, affecting millions worldwide, is characterized by severe headaches occurring at least 15 days per month, frequently accompanied by debilitating symptoms such as nausea and light sensitivity. Current treatment options often fail to deliver consistent and lasting relief.

ShiraTronics’ innovative system administers precise electrical pulses intended to disrupt migraine pain signals. Its unique, head-located design marks a significant departure from traditional neurostimulation systems typically intended for spinal placement. This novel approach is intended to address the mechanical and functional challenges unique to providing implantable stimulation to both the occipital and supraorbital nerves while delivering uninterrupted therapy 24 hours a day.

Key Highlights from the 12-Week Data:

Significant Reduction in Migraine Frequency: Participants experienced a substantial decrease in the number of headache and migraine days per month, alongside notable reductions in the severity of migraines.Improved Quality of Life: Participants reported marked enhancements in daily activities and overall well-being.High Safety Profile: The system demonstrated an excellent safety profile.

Dr. Falowski stated, “The RELIEV-CM study’s results are very promising. For the first time, we have a fully implantable neurostimulation system designed specifically for chronic migraine patients, placed in the head and above the flex points of the neck and spine. This customized approach reduced migraine frequency and significantly enhanced the quality of life for participants in the Pilot Study. This has the potential to be a transformative solution for millions suffering from chronic migraine disease.”

Physician Insights and Next Steps

Dr. Matthew Green, a Pain Medicine physician at Pain Med SA and the Director of CerCare Clinical Research in Adelaide, Australia, was among the first to implant the system. Reflecting on the Pilot Study, he said, “Our experience in this Australian Pilot Study has highlighted the positive health impacts of the innovative ShiraTronics Migraine Therapy System for chronic migraine suffers who have tried and failed standard treatment options. Excitingly, our participants have shown significant improvements in pain levels, migraine-days, and quality of life indicators. We look forward to continuing our involvement in the upcoming randomized controlled trial to further explore the benefits of this technology for patients worldwide.”

About ShiraTronics

ShiraTronics is a pioneering medical device company dedicated to developing state-of-the-art neurostimulation solutions aimed at improving the quality of life for patients with chronic migraine. “We are delighted to present these groundbreaking results to the global medical community,” said Rob Binney, President and CEO of ShiraTronics. “Our unwavering focus has always been on addressing the unmet needs of chronic migraine sufferers. The results of our Pilot Study validate the potential impact our therapy represents for the patients we serve, and who contend with the debilitating symptoms associated with chronic migraine. This data provides early indicators that our innovative platform has the potential to transform patient outcomes, restore functionality and improve quality of life. We are enthusiastic about accelerating our next phase of clinical research and continuing the relentless pursuit of our mission. Thank you to our Pilot Study investigators, advisors and, most importantly, our patients who participated in the RELIEV-CM Pilot Study.”

For more information about ShiraTronics and the RELIEV-CM study, please visit shiratronics.com.

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SOURCE ShiraTronics, Inc.

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CGTN: Starting a new era in Asia-Pacific development amid global uncertainty

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BEIJING, Nov. 16, 2024 /CNW/ — Over the decades, the Asia-Pacific region has been a vital driver of global economic growth. In October, the International Monetary Fund predicted the region would contribute approximately 60 percent to global economic growth in 2024.

At the same time, Asia-Pacific cooperation is confronted with challenges such as rising tendencies of geopolitics, unilateralism and protectionism. In this regard, Chinese President Xi Jinping on Saturday called on leaders of Asia-Pacific Economic Cooperation (APEC) members to shoulder greater responsibilities.

“We must act in solidarity and cooperation to meet the challenges, fully deliver on the Putrajaya Vision 2040, build an Asia-Pacific community with a shared future, and start a new era in Asia-Pacific development,” said Xi, when attending the 31st APEC Economic Leaders’ Meeting in Peru’s capital Lima.

China’s proposal

To deepen Asia-Pacific cooperation, the Chinese president on Saturday made three proposals.

Firstly, Xi stressed the need to build an open and interconnected paradigm for Asia-Pacific cooperation, calling for staying committed to multilateralism and an open economy.

China has made great efforts towards an open Asia-Pacific economy. According to the Chinese Foreign Ministry, China is the largest trading partner of 13 APEC economies and has actively advanced the building of the China-ASEAN Free Trade Area, promoted high-quality implementation of the Regional Comprehensive Economic Partnership (RCEP), and applied to join the Comprehensive and Progressive Agreement for Trans-Pacific Partnership (CPTPP) and the Digital Economy Partnership Agreement.

Secondly, Xi emphasized the need to make green innovation a catalyst for the Asia-Pacific, saying APEC economies should push forward coordinated digital and green transformation and development to create new momentum and new drivers for Asia-Pacific development.

China is developing new quality productive forces in light of actual conditions and deepening cooperation with interested parties on green innovation. Xi announced on Saturday that China will launch a Global Cross-Border Data Flow Cooperation Initiative.

China has put forward initiatives for cooperation between APEC member economies in green agriculture, sustainable city development, green and low-carbon energy transition, and marine pollution control and prevention.

The Chinese president also urged efforts to uphold a universally beneficial and inclusive vision for Asia-Pacific development. The data unveiled by the Chinese Foreign Ministry showed China contributes 64.2 percent of the region’s economic growth, 37.6 percent of the growth in goods trade, and 44.6 percent of the growth in services trade.

Xi told APEC leaders that China will advance initiatives through the APEC platform on increasing residents’ income and promoting the industrial cluster development of small- and medium-sized enterprises, for the purpose of bringing about universally beneficial and inclusive development of Asia-Pacific economies.

China’s commitments

China will host the APEC Economic Leaders’ Meeting in 2026, Xi announced on Saturday, saying China welcomes all parties to continue riding the “express train” of its development and grow together with the Chinese economy.

The Chinese president reiterated China’s commitments to reform and opening up. “Reform and opening up is a historic process in which China and the world achieve development and progress together,” he said.

The 20th Central Committee of the Communist Party of China, at its third plenum in July, laid out systematic plans for further deepening reform across the board with more than 300 consequential reform measures being unveiled, pertaining to building a high-standard socialist market economy, advancing high-quality economic development, promoting high-standard opening up, improving the people’s quality of life, and building a beautiful country.

In his written speech at the APEC CEO Summit on Friday, Xi also said China will introduce more policies for voluntary and unilateral opening up, expand its globally-oriented network of high-standard free trade areas, and open its door even wider to the world.

https://news.cgtn.com/news/2024-11-17/Starting-a-new-era-in-Asia-Pacific-development-amid-global-uncertainty-1yAvmNr7lYc/p.html 

View original content:https://www.prnewswire.com/news-releases/cgtn-starting-a-new-era-in-asia-pacific-development-amid-global-uncertainty-302307697.html

SOURCE CGTN

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CGTN: How does Chancay Port light up Asia-Pacific cooperation?

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BEIJING, Nov. 16, 2024 /CNW/ — From the arrival of the first ship at Chancay Port to its official inauguration, the port has gained global attention in recent days, boosting confidence in the prospects of more open and inclusive Asia-Pacific economic development.

The port, a cooperative project between Peru and China under the Belt and Road Initiative (BRI), will reduce sea shipping time from Peru to China to 23 days, cutting logistics costs by at least 20 percent. It is expected to generate $4.5 billion in annual revenue for Peru and create over 8,000 direct jobs. The port, capable of accommodating ultra-large container ships with a capacity of 18,000 twenty-foot equivalent units (TEUs), has a designed annual throughput capacity of 1 million TEUs in the near term and 1.5 million TEUs in the long term, positioning it as a key hub for trade between Latin America and Asia.

Noting that the port connects Chancay and Shanghai, Chinese President Xi Jinping remarked that “what we are witnessing is not only the root and blossom of the BRI in Peru but also the birth of a new gateway that connects land and sea, Asia and Latin America” during his address via video link at the port’s inauguration ceremony.

Peruvian officials: ‘More job opportunities and economic growth’ brought to Peru

Senior Peruvian officials and ordinary citizens have said they are looking forward to benefiting from the first smart and green port in South America.

Prime Minister of Peru Gustavo Adrianzen said that cooperation between China and Peru, including the Chancay Port project and other fields, will bring more job opportunities and economic growth to Peru, improving people’s living standards.

Jose Tam, president of the Chinese-Peruvian Chamber of Commerce, talked about the significance of Peru’s Chancay megaport with CGTN, saying the port will be an “engine” for the local economy.

Juan Carlos Capunay, former executive director of the APEC Secretariat and former Peruvian ambassador to China, also stated that the port will play an important role in deepening bilateral relations and fostering practical cooperation between China and Peru.

Entrepreneur Cielo Augusto from Chancay said he is looking forward to building the first levels of business while noting that industries such as hospitality will also be boosted, as there will be a significant influx of people from abroad.

“The port will save time, increase efficiency and bring new opportunities to Peru,” Karla Santuyomarca, a Peruvian citizen, told CGTN.

Some 78.3 percent of respondents to a CGTN survey of Peruvians said they support their country’s participation in the BRI, which includes Chancay Port. Additionally, 93.6 percent of respondents expressed support for deepening practical cooperation in various fields between China, Peru and other Latin American countries.

Open, interconnected Asia-Pacific cooperation

With its official opening on Thursday, Chancay Port is expected to integrate the entire Latin American region into the dynamic economic framework of the Asia-Pacific, greatly enhancing connectivity within and beyond the continent.

Peruvian Foreign Minister Elmer Schialer Salcedo said, “The Pacific Ocean does not separate us, but it connects us,” adding that Chancay Port will halve the time and costs of connecting South America with Asia.

Carlos Aquino Aquino Rodriguez, professor of Asian economies at San Marcos National University, said the port is crucial to the economic development and connectivity of the Asia-Pacific and can also promote mutual benefits for raw material buyers, suppliers of manufactured goods and investors.

In a CGTN global poll on Asia-Pacific cooperation, 93.7 percent of respondents called on all parties in the region to forge consensus and build an Asia-Pacific community with a shared future featuring openness and inclusiveness, innovative growth, connectivity and win-win cooperation.

https://news.cgtn.com/news/2024-11-17/How-does-Chancay-Port-light-up-Asia-Pacific-cooperation–1yAAAYcaP28/p.html

View original content:https://www.prnewswire.com/news-releases/cgtn-how-does-chancay-port-light-up-asia-pacific-cooperation-302307698.html

SOURCE CGTN

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Effeect’s CEO David Ispiryan Shares Insights on Maximizing PPC Campaigns Through AI and Machine Learning in Forbes Council Post

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David Ispiryan’s Forbes Article Offers Actionable Advice for Leveraging AI in PPC Advertising

SHERIDAN, Wyo., Nov. 16, 2024 /PRNewswire-PRWeb/ — David Ispiryan, CEO of Effeect and member of the Forbes Agency Council, recently published a featured article on Forbes titled “AI And Machine Learning In PPC: How To Automate For Maximum Results.” In this insightful piece, Ispiryan shares strategies for automating PPC advertising campaigns through AI and machine learning. This article aims to equip businesses with the knowledge needed to optimize PPC performance, reduce costs, and drive higher returns.

The digital advertising space is rapidly evolving, and AI-powered tools are changing how businesses approach PPC campaigns. From automated bid management to audience segmentation and predictive analytics, Ispiryan’s article on Forbes covers the core ways that AI and machine learning are transforming PPC.

Key Highlights from David Ispiryan’s Article

AI-Powered Bid Management: Bid management can be a complex and time-intensive task in PPC campaigns. Ispiryan highlights that AI algorithms streamline this process by automatically adjusting bids based on several factors. He explains that advertisers can automate their bids for optimized conversions. “AI-driven bid management allows businesses to spend less time adjusting bids” said Ispiryan. “Tools like Smart Bidding make it easier to achieve optimal ROI by targeting the most valuable customers.”Automated Ad Creation with Dynamic Search Ads (DSAs): Ispiryan underscores the importance of Dynamic Search Ads (DSAs), which automatically create ads based on a website’s content. By targeting long-tail keywords, DSAs help businesses capture high-intent users further along in the buying process. This automation fills potential keyword gaps, reaching audiences who are ready to convert.Enhanced Audience Targeting through AI: In his article, Ispiryan explains how AI tools analyze user behavior, demographics, and search history to create customized audiences. By using tools like Google’s Custom Audiences and Facebook’s Lookalike Audiences advertisers can ensure their ads resonate with their leads.Predictive Analytics for Smarter Budget Allocation: Predictive analytics allows advertisers to anticipate user behavior and make informed budget decisions. AI-powered tools in Google Ads and Microsoft Ads use historical data to predict conversion likelihood, making it easier for businesses to allocate budgets effectively. “Predictive analytics enables businesses to target users who are most likely to convert, maximizing the effectiveness of their ad spend,” said Ispiryan. “With predictive bid adjustments, companies can stay agile, responding to market changes in real time.”Automated A/B Testing with Responsive Search Ads (RSAs): A/B testing is crucial for PPC success, and Ispiryan discusses how Google’s Responsive Search Ads (RSAs) simplify this process. By inputting multiple headlines and descriptions, Google’s AI tests and determines the most effective combinations, continuously optimizing ad performance without manual effort.

Maximizing PPC Campaigns with AI and Machine Learning

According to Ispiryan, AI and machine learning are revolutionizing PPC by automating processes that once required hours of manual work. Through actionable advice in his Forbes article, Ispiryan urges businesses to set clear goals and regularly review campaign performance to ensure their automation strategies align with their broader marketing objectives.

“Automation is a powerful tool, but it works best when complemented by human insight,” Ispiryan concluded.

Read the Full Article

To explore more on these groundbreaking PPC automation strategies, read David Ispiryan’s full article on Forbes

Pull Quote

Automation is a powerful tool, but it works best when complemented by human insight.

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Bill Adams, Digital Marketing Agency, 1 3072882822, info@digitalmarketingarticle.com, https://digitalmarketingarticle.com/ 

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SOURCE Digital Marketing Agency; Digital Marketing Agency

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