Technology

10x Genomics Launches 5,000-Plex Gene Panel for Xenium

Published

6 months ago

May 29, 2024

New Xenium Prime 5K Pan-Tissue and Pathways panel increases plex by an order of magnitude and delivers industry-leading speed and throughput

PLEASANTON, Calif., May 29, 2024 /PRNewswire/ — 10x Genomics, Inc. (Nasdaq: TXG), a leader in single cell and spatial biology, announced today the launch of its Xenium Prime 5K Pan-Tissue and Pathways panel. The new assay features an enhanced chemistry to increase plex by an order of magnitude while delivering excellent per-gene sensitivity, improved specificity and spatial fidelity, integrated multimodal cell segmentation, and industry-leading speed and throughput.

“Seeing the Xenium Prime 5K data reminded me of the excitement I experienced when I saw single cell RNA-seq data for the first time,” said Dr. Kevin Wei, M.D., Ph.D., Assistant Professor of Medicine at Harvard Medical School. “Now, we can identify relevant molecular pathways in human diseases and explore new biological hypotheses, all from one glass slide.”

The high-plex Xenium Prime 5K assay enables a new level of exploration for pathways, biomarkers, ligand-receptor pairings and cell-cell interactions. Key features include:

Highest plex Xenium panel for comprehensive profiling of cell types and states and cell signaling pathways across multiple tissue and disease types.Excellent data quality to unlock mechanisms of disease, therapeutics and cell behavior. The Xenium Prime 5K assay is optimized for performance and paired with 10x Genomics’ advanced multimodal cell segmentation, enabling high sensitivity, specificity and spatial fidelity.Rapid turnaround time with easy, tissue-agnostic workflows. 10x Genomics’ industry-leading throughput enables researchers to analyze up to 472 mm² of tissue in six days or less.Easily customizable with up to 100 additional genes to capture customers’ specific research needs.Rigorously designed and developed using single cell RNA-seq data from dozens of different organs and tissues, gene expression profiles from hundreds of cell types and a screen of more than 750,000 peer-reviewed publications to pinpoint highly cited biomarkers.

“We successfully launched Xenium with a broad menu of curated and highly customizable gene panels so customers could target specific biology important for their research,” said Michael Schnall-Levin, Founding Scientist and Chief Technology Officer at 10x Genomics. “With the launch of our 5K gene panel, researchers can now also use Xenium for spatial exploration, enabling more biology and more breakthroughs. This assay is yet another example of how we put our innovation engine to work for our customers and build best-in-class products that deliver best-in-class results.”

The Xenium Prime 5K assay, optimized for human and mouse species, is now available for preorder and is expected to ship next month.

About 10x Genomics
10x Genomics is a life science technology company building products to accelerate the mastery of biology and advance human health. Our integrated solutions include instruments, consumables and software for single cell and spatial biology, which help academic and translational researchers and biopharmaceutical companies understand biological systems at a resolution and scale that matches the complexity of biology. Our products are behind breakthroughs in oncology, immunology, neuroscience and more, fueling powerful discoveries that are transforming the world’s understanding of health and disease. To learn more, visit 10xgenomics.com or connect with us on LinkedIn or X (Twitter).

Forward Looking Statements
This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 as contained in Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, which fall under the “safe harbor” provisions of those sections. All statements, other than statements of historical facts, may be forward-looking statements. Forward-looking statements generally can be identified by the use of forward-looking terminology such as “may,” “might,” “will,” “should,” “expect,” “plan,” “anticipate,” “could,” “intend,” “target,” “project,” “contemplate,” “believe,” “estimate,” “predict,” “potential” or “continue” or variations of them or similar terminology, but the absence of these words does not mean that a statement is not forward-looking. These forward-looking statements include statements regarding 10x Genomics, Inc.’s (“10x Genomics”) product launches, performance, configuration, capabilities, adoption and pipeline. These statements are based on management’s current expectations, forecasts, beliefs, assumptions and information currently available to management, and actual outcomes and results could differ materially from these statements due to a number of factors. Other risks and uncertainties that could affect 10x Genomics’ financial and operating results and cause actual results to differ materially from those indicated by the forward-looking statements made in this press release include those discussed under the captions “Risk Factors” and “Management’s Discussion and Analysis of Financial Condition and Results of Operations” and elsewhere in the documents 10x Genomics files with the Securities and Exchange Commission (the “SEC”) from time to time. Although 10x Genomics believes that the expectations reflected in the forward-looking statements are reasonable, it cannot provide any assurance that these expectations will prove to be correct nor can it guarantee that the future results, levels of activity, performance and events and circumstances reflected in the forward-looking statements will be achieved or occur. The forward-looking statements in this press release are based on information available to 10x Genomics as of the date hereof, and 10x Genomics disclaims any obligation to update any forward-looking statements provided to reflect any change in its expectations or any change in events, conditions or circumstances on which any such statement is based, except as required by law. These forward-looking statements should not be relied upon as representing 10x Genomics’ views as of any date subsequent to the date of this press release.

Disclosure Information
10x Genomics uses filings with the Securities and Exchange Commission, our website (www.10xgenomics.com), press releases, public conference calls, public webcasts and our social media accounts as means of disclosing material non-public information and for complying with our disclosure obligations under Regulation FD.

Contacts
Investors: investors@10xgenomics.com
Media: media@10xgenomics.com

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SOURCE 10x Genomics, Inc

Technology

BobVila.com Announces “Tool of the Year” Program and Inaugural Winners

Published

2 seconds ago

November 14, 2024

Featuring more than 30 products, the 2024 list celebrates the best new items that improve DIYer’s house projects

NEW YORK, Nov. 14, 2024 /PRNewswire/ — Today, BobVila.com proudly announces its inaugural Tool of the Year winners. The home-improvement-focused editorial brand launched its expansive and exciting program dedicated to celebrating the tools and products that make home DIY projects a more seamless and accessible experience.

Since 2011, BobVila.com has been carrying forward Bob Vila’s lifelong mission of educating and empowering Americans to build, fix, clean, chisel, and paint their way to a better living environment. The inaugural Tool of the Year Awards list features 36 winners across seven essential home-improvement categories: Hand Tools, Power Tools, Outdoor Tools, Hobbyist Tools, Gadgets and Tech, Cleaning Tools, and Multitools. Winning products combine utility, effectiveness, design, construction quality, and a spark of originality.

BobVila’s in-house writers, editors, product testers, and remodeling pros hand-selected each product. The winners include household names with innovative new products, such as DeWalt’s ToughSeries Construction Jack, Craftsman’s Verastack Mechanics tool set, Bissell’s CrossWave OmniForce Wet Dry Vac, Milwaukee’s Gen II 25′ Stud Heavy Duty Tape Measure with 17 ft. Reach, and Toro’s 60V Max 900 CFM Brushless Leaf Blower, as well as smaller businesses making a big splash, like Enbrighten’s Permanent Outdoor Lights, SimpliSafe’s Outdoor Camera 2 + Active Guard, Casabella’s Power Spin Scrubber, Flexcut’s Pro Range Wood Carving Knives, and Wera’s Click-torque Wrench.

“The Bob Vila brand’s mission to make home improvement more accessible often starts with helping homeowners choose the right tools for the task at hand. Our team passionately scouts for products that make projects and day-to-day to-do’s easier to get done. That’s why we launched our Tool of the Year Awards search,” said Editor-in-Chief Kathleen Corlett. “Our goal is to celebrate the products that stand out for their exceptional utility at home—whether they are traditional tools, problem-solving gadgets, or unique gear that makes tasks easier. We are proud to announce this diverse and exciting selection of tools, gadgets, and goods as 2024 winners of the inaugural BobVila.com Tool of the Year Awards.”

The team also awarded Grizzly’s 21″ Variable-Speed Scroll Saw with Foot Pedal a DIY Game Changer award, an honor reserved for the year’s most exciting innovation. The Grizzly team reimagined the scroll saw design to offer more user control and precision, effectively making the craft even more accessible to beginners and experienced woodworkers alike. More information and the complete list can be found on BobVila.com.

ABOUT BOBVILA.COM
For nearly 30 years, Bob Vila showed people how to renovate and repair their homes. As the host of This Old House, Bob Vila’s Home Again, Restore America, and other groundbreaking television series, Bob Vila became known as the godfather of the current DIY movement. Since 2011, BobVila.com has been carrying forward Bob’s lifelong mission of educating and empowering Americans to build, fix, clean, chisel, and paint their way to a better living environment. A complete content toolbox, the brand provides accessible inspiration, advice, and nitty-gritty know-how across thousands of easy-to-understand guides and tutorials, on topics ranging from vegetable gardening to furnace repairs. BobVila.com is a part of Recurrent, a digital media company with over 15 enthusiast brands.

View original content:https://www.prnewswire.com/news-releases/bobvilacom-announces-tool-of-the-year-program-and-inaugural-winners-302306089.html

SOURCE BobVila.com

Technology

Introducing Level Lock+ (Matter): The World’s Most Advanced Smart Lock

Published

4 seconds ago

November 14, 2024

Endless compatibility: Matter support, Apple home keys, and Bluetooth — all within a design that enhances any home aestheticBuilt for the future: owners of previous generations of Level Lock+ can now update to Matter in a few simple steps

REDWOOD CITY, Calif., Nov. 14, 2024 /PRNewswire/ — Level Home today introduced Level Lock+ (Matter), the world’s smallest and most advanced smart lock. True to Level’s hallmark “invisible” design, this new version seamlessly integrates with major smart home systems. It enhances home aesthetics while offering secure, flexible control through Bluetooth and Matter-over-Thread, compatible with ecosystems from Google, Amazon, Apple, and Samsung.

“Technology in the home should always empower and never intrude,” said Ken Goto, Vice President and CTO of Level Home.

Every Level lock makes coming and going easier than ever, delivering the highest level of convenience, security, and control over home access. Through the Level app, users have complete control over their lock, with options to share access with guests, enable auto lock and unlock, view real-time activity history, and adjust custom access controls, letting users invite and manage trusted visitors from anywhere. No other smart lock has so many layers of access: mobile device, Level Key Fobs, the optional Level Keypad, and the traditional physical key.

The Only Smart Lock That Keeps Getting Better

The new device joins Level’s portfolio of smart locks that are the only ones on the market designed to evolve continuously, bringing new features and enhancements directly to customers. Through firmware updates, it adapts to new technology and changing user needs —without requiring replacement. This ensures users can rely on their Level lock for security, convenience, and seamless integration in the years ahead.

“We build our locks to be incredible out of the box and to keep getting better over time,” said John Martin, President and Head of Level Home. “With Level Lock+ (Matter), customers can simply connect with whatever matter-based smart home ecosystem they want—and have peace of mind that their lock will adapt as technology evolves in the future.”

Future-Proof Your Existing Level Lock+

The company also announced a free Matter firmware update program, allowing current Level Lock+ owners to seamlessly update their existing devices with the latest technology. With this program, customers can enjoy enhanced smart home functionality without the expense or hassle of replacing hardware—an advantage of Level’s forward-thinking design and engineering. For details. visit level.co/matter-update/.

Smallest Design, Biggest Functionality

At 62% smaller than other smart locks, Level Lock+ (Matter) packs cutting-edge technology into the world’s smallest form—all while maintaining a sleek, compact design that complements any home. No peripherals, add-ons, or unsightly technology are tacked on.

“Technology in the home should always empower and never intrude,” said Ken Goto, Vice President and CTO of Level Home. “We put the principle of ‘invisibility’ at the core of everything we do, creating smart locks that integrate naturally into daily life. This latest lock brings security, connection, and seamless integration, all without the need for bulky hardware or obtrusive tech.”

One Lock, Endless Compatibility

Level’s Matter implementation for Level Lock+ is the first smart lock to concurrently support both Bluetooth and Matter-over-Thread, allowing users to connect with multiple platforms at once:

Apple Home, with support for home keysGoogle HomeAmazon AlexaSamsung SmartThings

Starting today, Level Lock+ (Matter) is available in Matte Black and Satin Nickel on level.co.

About Matter

Matter is a universal smart home connectivity standard designed to add compatibility across a range of smart home devices, regardless of brand. With Matter-enabled products (like Level Lock+ with Matter), users can control their smart home ecosystem more easily through their preferred platforms. Matter-over-Thread, specifically, offers a low-power, low-latency network that enables faster and more secure device connections without needing Wi-Fi. This makes managing a connected home more seamless, flexible, and user-friendly.

About Level Home

Level Home, an ASSA ABLOY Group brand, is transforming the smart home landscape with its approach to invisible technology. We have purposely started our journey at square zero and choose to design products that make “smart” invisible. By focusing on elegant design, uncompromising quality, and forward-thinking engineering, Level Home creates products that bring people together, without compromising on the home’s aesthetics. With Level Lock+, the world’s smallest and most innovative smart lock, and Level Bolt, the first invisible smart lock, Level continues to lead the market in creating seamless and sustainable home solutions. For more information, please visit level.co.

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SOURCE Level Home, Inc.

Technology

Predactica Achieves Snowflake Ready Technology Validation, Expands Integrations and Solutions with Snowflake

Published

5 seconds ago

November 14, 2024

Validation program optimizes Predactica’s AI / ML-focused Snowflake integrations with emphasis on functional and performance best practices.

DALLAS, Nov. 14, 2024 /PRNewswire-PRWeb/ — Predactica today announced that it has been approved by Snowflake, the AI Data Cloud company, as a Snowflake Ready Technology Validation partner, confirming that the company’s Snowflake integrations adhere to the platform’s best practices around performance, reliability, and security.

“Predactica’s no-code AI and ML SaaS platform for citizen data scientists can help ensure seamless user experience for our joint customers leveraging Predactica’s native integrations with Snowflake.” – Tarik Dwiek, Head of Technology Alliances at Snowflake

“With this validation, customers can fully trust that our technology and integrations are tested and proven to work seamlessly with Snowflake,” said Pawan Bhati, VP of Marketing, Predactica. “We’ve been a proud Snowflake partner and this validation demonstrates our continued commitment to our shared vision for the modern data stack. Additionally, with our support for AI Agents, we empower businesses to drive even greater operational efficiencies and intelligence within the Snowflake ecosystem”.

The Snowflake Ready Validation Program recognizes partners that have completed a third party technical validation to confirm their Snowflake integrations are optimized with an emphasis on functional and performance best practices. This validation comes on the heels of recent expanded integrations and solutions for Predactica and Snowflake, including:

Predactica’s Snowpark Accelerated validation for AI and machine learning (ML), enabling customers to quickly and efficiently execute machine learning workflows and collaborate on the Snowflake Data Cloud with native SQL integrations.Predactica’s explainable AI (XAI) integration with Snowflake, helping customers decode black box AI models.Predactica’s MLOps capabilities integrated with Snowflake, enabling customers to deploy, monitor, and validate models without ever leaving their Snowflake environment.

To understand how Predactica can help you accelerate your Snowflake investment please contact us at www.predactica.com/contactus

Media Contact

Sridhar Ratakonda, Predactica, 1 4692606593, sratakon@predactica.com, www.predactica.com

View original content:https://www.prweb.com/releases/predactica-achieves-snowflake-ready-technology-validation-expands-integrations-and-solutions-with-snowflake-302300897.html

SOURCE Predactica; Predactica

Technology5 days ago

CloudOne Digital Appoints Packet Cofounder and Former Equinix Executive Zach Smith to Board of Directors to Drive Growth in Bare Metal and Hybrid-Cloud Solutions