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Wheeler Bio Seals Agreement with Charles River to Offer Portable CMC® to Discovery Clients to Accelerate Their Journey to First-in-Human Use

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WILMINGTON, Mass. and OKLAHOMA CITY, Feb. 29, 2024 /PRNewswire/ — Wheeler Bio, Inc., an agile contract development and manufacturing organization (CDMO), announced today a new strategic agreement with Charles River Laboratories International, Inc. (NYSE: CRL), a global leader in pharma services, to offer Wheeler Bio’s Portable CMC® (Chemistry, Manufacturing and Controls) platform to Charles River Laboratory clients. The collaboration is designed to enable a swift transition from pre-clinical stages directly to human clinical trials.

Combining Charles River’s industry-leading experience in antibody discovery services, safety, and analytics with Wheeler’s Portable CMC® platform will accelerate therapeutic discovery to Investigational New Drug (IND) submission timelines. This umbrella offering efficiently connects the preclinical, clinical manufacturing, and release testing journeys, significantly reducing the complexity of managing multiple vendor relationships. Integrating CMC development early in discovery enables therapeutic developers to collaborate with experts across the organizations to utilize phase-appropriate manufacturing and analytics. The services and expertise come together to provide a single concept-to-commercial offering.

Wheeler Bio’s mission is to solve translational challenges inherent in advancing from discovery to CMC development and early-clinical trial material supply. Their Portable CMC® is a validation-ready production process which reduces technical and regulatory risk. The organization operates the Portable CMC® platform in Wheeler’s state-of-the-art process development labs in Oklahoma City, OK, which also houses a CGMP facility-of-the-future including a RightSource™ quality control testing lab. There is an additional satellite lab in Waltham, MA featuring protein sciences and bench scale process capabilities. Wheeler Bio provides startup biotechs with access to a high quality, agile, affordable path to clinical supply with thoughtfully designed, modular work packages featuring the industry leading Leap-In Transposase® mediated gene delivery system from ATUM for robust high titer CHO pool-based workflow parallelization, standard analytics, and discrete CMC milestones that align with innovators’ fundraising milestones.

Jesse McCool, CEO and Co-Founder of Wheeler Bio, stated, “Wheeler is excited to expand our relationship with Charles River and to link with their discovery organization.  By integrating discovery CRO and CDMO workflows, we can speed our clients’ path to first-in-human trials through better insights, thereby achieving clinical decisions faster. Our combined sales teams look forward to co-promoting these services for the benefit of our biotech partners and their pipelines towards clinical impact.”

Julie Frearson, Corporate Senior Vice President, Chief Scientific Officer at Charles River, highlighted the potential of this partnership: “We are thrilled to provide our clients with access to Wheeler’s innovative Portable CMC® platform, which will optimize their workflows and ultimately bring new treatments to patients faster.”

About Wheeler Bio
Wheeler Bio is a biomanufacturing pioneer, founded by a team of industry experts and strategic investors who believe a different CDMO model is needed to help innovators reach their clinical milestones faster. Wheeler’s novel hub-and-spoke operational model, centered in the biomanufacturing metro of Oklahoma City, and integrated with biotechs and discovery CROs, will revolutionize the speed of drug development. Wheeler Bio’s technology platform, Portable CMC® simplifies the path between drug discovery and clinical manufacturing by providing a new bridge for translating discoveries to first-in-human trials. Innovators benefit from increased momentum during technology transfer, shorter timelines, reduced risk, and lower costs. Additional information can be obtained by visiting www.wheelerbio.com or by following Wheeler Bio on LinkedIn

About Charles River
Charles River provides essential products and services to help pharmaceutical and biotechnology companies, government agencies and leading academic institutions around the globe accelerate their research and drug development efforts. Our dedicated employees are focused on providing clients with exactly what they need to improve and expedite the discovery, early-stage development and safe manufacture of new therapies for the patients who need them. To learn more about our unique portfolio and breadth of services, visit www.criver.com.

About ATUM
ATUM is a fully integrated Californian based CRDO (Contract Research & Development Organization) biotechnology industry leader. ATUM, over the last two decades, has served life science researchers by delivering high quality services including but not limited to Gene Design and Gene Synthesis, Protein Engineering, Protein Production, Leap-In Transposase®, Cell Line Development, and Master Cell Banking (MCB).  With a state-of-the-art machine learning platform, proprietary algorithms, and a fully integrated Laboratory Information Management System (LIMS), ATUM provides platforms and services that span from virtual sequence to manufacturing ready MCB. ATUM has a culture of continuous commitment to innovation where solutions are built on bioengineered solutions to bring speed to market, supporting the biotech ecosystem from pre-clinical research through IND and beyond. Contact us today for more information at www.atum.bio.

For Further Information:
Wheeler Bio, Inc.
Contact: Jaden Polston
jpolston@wheelerbio.com

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Aiper Unveils a New Poolside Hero at CES: Introducing the Scuba X1 Pro Max

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The pinnacle of pool cleaning, the Scuba X1 Pro Max touts power and precision for perfect pools

LAS VEGAS, Jan. 9, 2025 /PRNewswire/ — Aiper, the global creator of award-winning smart yard technology, today announces the launch of its latest innovation in pool maintenance, the Scuba X1 Pro Max robotic pool cleaner. Combining power, precision, and intelligence, the Scuba X1 Pro Max delivers an unmatched pool cleaning experience, transforming tedious maintenance into a simple and effortless routine.

From the surface to the floor, and every corner in between, the Scuba X1 Pro Max cleaning coverage is unbeatable. Featuring OmniSense+™ 2.0, an advanced pool mapping system equipped with 40 ultrasonic sensors for adaptive path planning, the unit ensures a precise and efficient cleaning. And powered nine motors providing the world’s strongest suction at 8,500 gallons per hour (GPH), the Scuba X1 Pro Max also includes a patented MicroMesh™ ultra-fine filter to capture the smallest debris for an unmatched deep clean.

The all-in-one robotic pool cleaner intelligently adjusts its cleaning path using the FlexiPath™ 2.0 system, while Auto Mode optimizes suction power based on the pool’s debris levels, significantly boosting both cleaning efficiency and runtime. With a battery life of up to 10 hours when operating on the surface, along with true cordless operation, pool owners can enjoy a tangle-free and worry-free cleaning experience.

Additionally, the Scuba X1 Pro Max includes the brand’s new HomeComingDock™, enabling easy surface retrieval via the Aiper app, while a seamless integration with the optional HydroComm Pro provides real-time water quality monitoring, including metrics such as pH, temperature, and pool maintenance recommendations. The Scuba X1 Pro Max will be available for purchase in mid-February 2025 at $2,299 (MSRP) and will include a wireless charging dock. For a limited time, early customers will also receive a free Aiper Caddy for an easy and convenient way to transport and charge the Scuba X1 Pro Max when out of the water.

“At Aiper, we are constantly pushing the boundaries of what robotic pool cleaners can do and resetting the industry standard. The Scuba X1 Pro Max represents a significant leap forward, combining advance technology with user-friendly and user-centric design to deliver an effortless and enjoyable pool-cleaning experience,” said Richard Wang, CEO of Aiper.

To celebrate the new line up products, Aiper is thrilled to be named the Official Robotic Pool Cleaner of the Arizona Diamondbacks. Providing industry-leading entertainment in a clean, safe and family-friendly environment, MLB’s D-backs call Chase Field, in downtown Phoenix, home. Chase Field is the first Major League Baseball stadium to feature a pool, and Aiper will be keeping this famous water feature sparkling clean all season long. As part of the CES trade show launch event on January 8, former D-back outfielder, Luis “Gonzo” Gonzalez, along with the organization’s senior vice president of corporate partnerships, Steve Mullins, were in attendance at the Aiper booth (#52311) to show their support.

For more information about the Scuba X1 Pro Max visit www.aiper.com and follow Aiper on LinkedInFacebookInstagramTikTok, and X.

About Aiper

Aiper is the leading global creator of innovative cordless robotic pool cleaners on a mission to Bring Vacation Home by inspiring pool owners to turn their backyards into a personal oasis with the help of smarter cleaning solutions. After doing a deep dive into the pain points of traditional pool cleaners, the company embarked on a path to merge technology with innovative design to create the world’s most easy-to-use robotic pool cleaners that are not only cord and hassle-free but can automatically handle all the dirty work so pool owners can stop manually cleaning. Unlike other products on the market, each Aiper robot is guaranteed to minimize the time and money spent cleaning and give more time back to enjoy quality time with friends and family by the pool. Through that, Aiper has earned its place as the world’s best cordless robotic pool cleaner since its launch. In 2023 and 2024, Aiper products have been named CES Innovations Award Honorees.

 

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TENNIS: PIRELLI AND AUSTRALIAN OPEN SIGN A MULTI-YEAR PARTNERSHIP BEGINNING FROM 2025

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MELBOURNE, Australia, Jan. 9, 2025 /PRNewswire/ — From this year, Pirelli will be the Official Tyre Partner of the Australian Open, which will start on Sunday 12 January in Melbourne. After motorsport, football, sailing and skiing, Pirelli enters tennis, choosing to support the Grand Slam with a partnership which represents a high-profile showcase for promoting the brand throughout the world.

Andrea Casaluci, CEO of Pirelli: “For Pirelli, the Australian Open represents a very important opportunity for visibility because of the great interest in tennis at the global level. In particular, the sponsorship will help increase awareness of our brand in Australia which is a market with a high concentration of prestige cars. Precisely in Melbourne, home of the tournament, in 2019 we opened a Pirelli P Zero World, our flagship store model currently present in only four other cities in the world”.

Cedric Cornelis, Tennis Australia Chief Commercial Officer: “We are very pleased to announce Pirelli as the Official Tyre Partner of the Australian Open. Pirelli is synonymous with innovation and performance, making it a great fit for one of the world’s premier tennis events. We are delighted that Pirelli has chosen the Australian Open to mark its first investment in a Grand Slam.”

PIRELLI AND SPORT

Pirelli’s connection with tennis dates to 1930 when the company began making tennis balls, until the 1970s. The passion for sport has always characterized the history of Pirelli, as demonstrated by the different disciplines in which it participates, from football to sailing to skiing. In motorsport, where Pirelli has competed since 1907, it is today present in over 350 competitions starting from the top level with Formula 1©.

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IndiaBonds.com Launches Digital Fixed Deposits – Expands Fixed Income Product Suite

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MUMBAI, India, Jan. 9, 2025 /PRNewswire/ — IndiaBonds.com, a SEBI-registered Stock Broker (Debt Segment) & licensed Online Bond Platform Provider (OBPP), has launched Digital Fixed Deposits (FDs), making fixed-income investments more accessible and convenient for individual investors across India. With this addition, IndiaBonds.com now offers a unified platform for managing both bonds and fixed deposits seamlessly, bringing all fixed-income investments under one ambit. This launch is in line with IndiaBonds’ vision to deliver stable and rewarding investment options to retail investors while simplifying portfolio management.

The platform offers a fully digital, paperless onboarding process, including quick KYC completion, making it easy for retail investors to get started. On the platform, the investors can earn up to 9.4% interest in their fixed deposit investments. Its integrated portfolio dashboard provides clear insights into cashflows, returns, and fixed income allocations, helping investors track and manage their investments efficiently.

By combining the stability of fixed deposits with the big flexibility of bonds, the platform empowers investors to build balanced, diversified portfolios. Additionally, investors benefit from customizable payout options, low minimum investment requirements, and the convenience of managing all their fixed-income investments in one place. The platform will expand its offerings with additional FD partners in the coming weeks.

Vishal Goenka, Co-founder of IndiaBonds.com, said, “At IndiaBonds, we have always focused on making regulated fixed-income investments simple, transparent, and accessible for individual investors. The launch of Digital Fixed Deposits is a natural step forward in our journey of expanding product offerings. By integrating bonds and FDs on one platform, we are enabling investors to optimize their portfolios effortlessly and take full advantage of fixed-income opportunities in the current market environment.”

He added, “We are committed to continuously evolving our platform and product suite to provide clients with seamless access to stable and diversified investment options, empowering them to make informed financial decisions with ease.”

This innovative offering not only caters to the growing demand for diverse investment options but also reinforces IndiaBonds.com’s commitment to empowering individual investors with tools to make informed and rewarding financial decisions.

About IndiaBonds

Launched in 2021, IndiaBonds is a SEBI-registered leading Online Bond Platform Provider. It provides access to investors in the fixed-income market in a low-cost, transparent, and easy-to-use manner.

At the helm of this bondtech company are industry veterans — Vishal Goenka, Co-Founder, and Aditi Mittal, Co-Founder & Director. This core team is committed to pioneering the digital revolution in the corporate bond market in India.

IndiaBonds provides a wholesome solution to bond investing to its customers and enables them to unlock the value of the fixed-income asset class. The experienced team assists investors with access to a wide choice of bond investment opportunities that provide stability, generate predictable income, and meet their investment objectives.

Within the Online Bond Platform Providers community, IndiaBonds is recognized as a revolutionizing fintech start-up owing to some of its ground-breaking innovations in the fixed-income industry.

In 2022, it announced the launch of its strategic tool, the Bond Yield Calculator, which aids investors by simplifying the complexities of calculating corporate bond prices and yield.

In 2021, it launched a comprehensive Bond Directory for the general public to have detailed information on all INR-denominated bonds outstanding in India.

 

View original content:https://www.prnewswire.com/in/news-releases/indiabondscom-launches-digital-fixed-deposits–expands-fixed-income-product-suite-302346780.html

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