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Alys Pharmaceuticals launches with $100M financing from Medicxi to advance Immuno-Dermatology focused pipeline

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Co-founded by world leading dermatology experts and Medicxi Merger of six asset-centric companies to form a new R&D-centric multi-platform pipeline in immuno-dermatology to harness cutting edge-science and technologiesVision to transform the treatment paradigm for several dermatology indications of significant prevalence and major unmet need

BOSTON and GENEVA, Switzerland, Feb. 12, 2024 /PRNewswire/ — Alys Pharmaceuticals, Inc. (“Alys”), an immuno-dermatology focused company, launches today with an R&D pipeline enabled by multiple platform technologies and a $100 million financing by Medicxi. Originating from the aggregation of six asset-centric Medicxi companies, Alys boasts a robust pipeline of innovative programs and platforms targeting multiple dermatological indications.

Co-founded by Medicxi and several world leading dermatology and scientific experts, including John Harris (UMass Chan Medical School), Brian Kim (Icahn School of Medicine at Mount Sinai), Lars French (LMU, Munich), Nobel Prize winner Craig Mello (UMass Chan Medical School), Eric Deutsch (Gustave Roussy) and Mark Prausnitz (Georgia Institute of Technology), Alys aspires to redefine the landscape of dermatological treatments. The Company is run by co-founder and COO Thibaud Portal (formerly Galderma’s Global Head of Prescription Medicines) and Medicxi’s Francesco De Rubertis serves as Chairman of the Board.

Alys believes that emerging indications such as atopic dermatitis, vitiligo, alopecia areata and chronic spontaneous urticaria, will see the next breakthroughs in dermatological advancements. The pipeline also includes programs focused on underserved indications such as mastocytosis, cutaneous T-cell lymphoma or prevention of skin side effects of oncology therapies.

Alys is working with leading institutions such as Institut Gustave Roussy, UMass Chan Medical School, Icahn School of Medicine at Mount Sinai, Georgia Institute of Technology and Empa, the Swiss Federal Laboratories for Materials Science & Technology, demonstrating its commitment to collaborative research and development.

Alys combines the assets and platforms of Aldena Therapeutics, Graegis Pharmaceuticals, Granular Therapeutics, Klirna Biotech, Nira Biosciences and Vimela Therapeutics. With more than a dozen active programs, Alys anticipates further organic pipeline growth from its cutting-edge platforms, covering inflammatory diseases, autoimmune diseases, dermatology supportive care for cancer patients and rare dermatoses. Over the next three years, the company aims to deliver between seven to ten clinical Proof-of-Concept (POC) readouts, and potentially at least one program to advance to registrational studies.

Francesco De Rubertis, Chairman of Alys Pharmaceuticals and Partner at Medicxi commented: “We believe that bringing together several asset-centric companies with a phenomenal team will power up Alys to transform innovation in immuno-dermatology. Alys manages a broad pipeline of assets with diverse risk profiles and will hugely benefit from this change of scale and facilitated access to capital.”

Professor John Harris, Chief Innovation Officer of Alys Pharmaceuticals and Chair of Dermatology at UMass Chan Medical School, added: “It is uniquely exciting to oversee such a rich and diverse pipeline, bringing forward modalities that will break new ground in dermatology, including peptides, sophisticated antibodies, or vectorized siRNA.”

Professor Brian Kim, Vice Chair of Research in the Department of Dermatology at the Icahn School of Medicine at Mount Sinai, added: “With its diverse pipeline, Alys’ commitment to advancing the frontiers of immuno-dermatology has the potential to bring transformative solutions to patients worldwide.”

About Alys Pharmaceuticals

Alys Pharmaceuticals, Inc. (“Alys”) is a Boston and Geneva-based cutting edge pure-play immuno-dermatology company. Alys is backed by international investment firm Medicxi with $100M financing. Alys has a world class leadership team that brings together experts across dermatology and advanced scientific fields, including co-founders Craig Mello (UMass Chan Medical School), John Harris (UMass Chan Medical School), Brian Kim (Icahn School of Medicine at Mount Sinai), Lars French (LMU, Munich), Eric Deutsch (Gustave Roussy) and Mark Prausnitz (Georgia Institute of Technology). Alys is led by dermatology specialist, co-founder and COO Thibaud Portal

It was formed from the aggregation of 6 asset-centric Medicxi companies – Aldena Therapeutics, Graegis Pharmaceuticals, Granular Therapeutics, Klirna Biotech, Nira Biosciences and Vimela Therapeutics. Its pipeline boasts 14 active programs, targeting multiple dermatological indications, including atopic dermatitis, vitiligo, psoriasis and mastocytosis. For further information, please visit www.alyspharma.com.  

About Medicxi

Medicxi is a healthcare-focused investment firm with the mission to create and invest in companies across the full drug development continuum. Leveraging deep expertise in drug development and company creation spanning over two decades, Medicxi invests in early and late-stage therapeutics with a product vision that can fulfill a clear unmet medical need. For more information, please visit: www.medicxi.com.

COI Statement

Mount Sinai and Brian Kim, UMass Chan Medical School, Craig Mello and John Harris, Georgia Institute of Technology and Mark Prausnitz, Gustave Roussy and Eric Deutsch, Lars French have financial interests in Alys.

 

View original content:https://www.prnewswire.co.uk/news-releases/alys-pharmaceuticals-launches-with-100m-financing-from-medicxi-to-advance-immuno-dermatology-focused-pipeline-302059125.html

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Reliable Link: Pioneering a New Era of Reliable Connectivity for Everything

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HONG KONG, Dec. 24, 2024 /PRNewswire/ — In this era where everything is connected, reliable communication networks have become more than just a service provided by operators; they are the key to linking the entire ecosystem of devices. Breaking down barriers between terminal equipments, allowing every corner and every device to be ‘reliably connected anytime, anywhere,’ is not only a technological breakthrough but also a beautiful vision for the future way of life. GrowthEase, in partnership with China Telecom, has brought together a top-tier team of communication technology experts to co-develop the “Reliable Link” project. Centered around the three core principles of “Reliability, Openness, and Ubiquity,” this project utilizes innovative communication technologies to integrate advanced cloud-network capabilities into various ubiquitous terminal devices such as drones, smart cameras, smart speakers, and smart locks. This aims to break the traditional constraints of terminal forms and capabilities, ushering in a new era of reliable communication connectivity. Leveraging the open capabilities provided by GSMA Open Gateway, and relying on the high-quality global network nodes deployed by NetEase Zhiqi and China Telecom, this project ensures end-to-end latency for audio and video calls remains within 200ms, guaranteeing 99.9% lag-free call experiences. Through highly reliable connectivity services, the project prioritizes the quality and security of connections and transmission in any environment, realizing “reliable connectivity anytime, anywhere” across all types of ubiquitous terminal devices.

Specifically, the Reliable Link project, through the Reliable-link AS platform and the Reliable-link applet, allows users to remotely control terminals like drones during a mobile voice call. For example, in the drone inspection scenario, Reliable Link can retrieve real-time flight routes, and with the Geofencing feature, set up electronic fences to ensure the drone stays within a safe area. When the drone detects a hazardous behavior, such as smoking, the system automatically triggers an alert and reports the location. Reliable Link combines VoLTE capabilities to initiate a video call to regional managers’ mobile phones, promptly pushing the alert information. Through Dev Loc verification and Location retrieval, the drone’s position is confirmed. Once the manager answers the video call, the QOD feature ensures high-quality video transmission, allowing the manager to issue control commands in real time through the call interface to control the drone’s flight. This not only ensures network reliability but also brings more efficient cross-terminal communication and smarter device management, making interactions between different devices smoother and more convenient, truly realizing “seamless connectivity” across ubiquitous terminal devices.

The Reliable Link Drone Communication Connectivity Project tightly integrates drones with the PaaS communication infrastructure, empowering drones with high-reliability, high-quality communication transmission capabilities. This drives upgrades and innovation in the drone industry, contributing to the prosperity of the low-altitude economy. Looking ahead, Reliable Link will continue to innovate and collaborate with ecosystem partners, establishing industry benchmarks. From connecting everything to empowering countless industries, the project aims to create a new landscape for reliable communication applications, enabling the thriving development of industries worldwide.

View original content:https://www.prnewswire.com/apac/news-releases/reliable-link-pioneering-a-new-era-of-reliable-connectivity-for-everything-302338544.html

SOURCE China Telecom

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BeyondTrucks Streamlines EDI Transaction Management Processes with Orderful Partnership

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BeyondTrucks and Orderful solution brings EDI workflow into an updated, intuitive and timesaving format for trucking companies

SAN MATEO, Calif., Dec. 23, 2024 /PRNewswire-PRWeb/ — BeyondTrucks, a transportation management system provider that delivers streamlined operations to private and specialty fleets through a connected and configurable platform, has announced a partnership with Orderful to embed their Electronic Data Interchange (EDI) Platform in the company’s multi-tenant SaaS Transportation Management System (TMS).

BeyondTrucks’ commitment to simplifying fleet operations aligns perfectly with Orderful’s mission to modernize EDI.

“EDI of the past is opaque, time-consuming, expensive and just simply outdated,” said Hans Galland, chief executive officer at BeyondTrucks. “Now with Orderful as our partner, our customers can elect to use the Orderful portal to manage EDI transactions in a rapid intuitive manner for all transactions and all trading partners. We are eliminating the need for a custom integration into BeyondTrucks with each and every partner.”

Embedded in the BeyondTrucks TMS, the Orderful EDI Platform seamlessly builds EDI connections between shippers and carriers by converting EDI data via an API. The integration provides users with real-time data synchronization, instant visibility, automated compliance checks, and intuitive error handling.

BeyondTrucks is also offering their fleet customers access to the Orderful portal for visibility into EDI data from shippers. The optional capability provides an interface where fleets can see when shippers make changes to load information but don’t communicate them or they are not passed through to the TMS. The carrier can then respond manually to avoid loads being missed or the shipper being poorly serviced.

“BeyondTrucks’ commitment to simplifying fleet operations aligns perfectly with Orderful’s mission to modernize EDI,” said Jonathan Kish, chief revenue officer at Orderful. “By embedding our platform, BeyondTrucks customers gain real-time visibility and faster connections, eliminating the headaches of traditional EDI and enabling them to operate more efficiently.”

The BeyondTrucks flexible, multi-tenant SaaS solution combines system integrations, proprietary modules, and adaptable configurations in a seamless platform to unify data and workflows for automation and optimization of fleet operations. Advanced capabilities of the cloud-based platform include order intake automation, smart load planning, dispatch communication, configurable driver workflows, and flexible automation of invoicing and driver payroll.

About Orderful

Orderful is the modern EDI Platform revolutionizing how logistics providers, retailers, manufacturers, and technology companies manage their EDI trading partnerships and transactions in real-time. Its simplified integrations, pre-connected network, and user-friendly self-service approach minimize errors with customers onboarding new partners. Orderful has been recognized as a best-in-class EDI provider by industry leaders like G2 and SourceForge. To learn more, visit https://www.orderful.com/.

About BeyondTrucks

San Francisco, California-based BeyondTrucks is the provider of a configurable and connected multi-tenant SaaS Transportation Management System (TMS). The SOC2-compliant software allows specialty and private fleets to replace legacy TMS, add-on solutions, and fragmented manual processes with a modern platform that creates seamless workflows driven by unified data. Designed to handle the complexities of large specialty and private fleets, the highly configurable BeyondTrucks platform achieves deeper levels of adoption and intelligent automation fleets to make fleet operations smarter, simpler, and stronger. With the multi-tenant platform, fleets also benefit from more efficient integrations into other fleet technology providers so that all parts of a fleet are always in sync. For more information, visit http://www.beyondtrucks.com.

Media Contact

Susan Fall, Launchit PR, 6198909415, susan@launchitpr.com, www.launchitpr.com

View original content to download multimedia:https://www.prweb.com/releases/beyondtrucks-streamlines-edi-transaction-management-processes-with-orderful-partnership-302338443.html

SOURCE BeyondTrucks

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GDIN Successfully Supports Establishment of 10 New Joint Ventures in 2024 Alone

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GDIN CEO Jongkap Kim: “By matching technology needs with local markets, we create long-lasting joint ventures with multiple exit opportunities.”

SEOUL, South Korea, Dec. 23, 2024 /PRNewswire/ — Global Digital Innovation Network (GDIN), led by CEO Jongkap Kim, proudly announced the major achievements of its 2024 Joint Venture Program. This program, which supports the establishment of joint ventures between South Korean companies and international partners, is designed to lower market entry barriers and create sustainable growth opportunities through local collaborations.

Since the launch of the program in 2021, GDIN has supported the establishment of 44 joint ventures across various regions. This year alone, 10 joint ventures were successfully launched in 8 countries including the United States, Canada, Japan, India, Singapore, Vietnam, UAE, and Uganda.

The Joint Venture Program was created to address a common challenge faced by early-stage tech companies: while they may have products and services that meet market demand, they often lack the resources and workforce to enter international markets. Through this program, GDIN helps companies increase their chances of success by facilitating strategic market entry via local partnerships.

In addition to the 44 joint ventures established so far, 47 partnership agreements are in the pipeline for future joint ventures. The program’s success is largely attributed to GDIN’s extensive global network of partners, which includes government organizations, multinational corporations, and international agencies such as the World Bank, Central American Bank for Economic Integration (CABEI), Inter-American Development Bank (IDB), Investment Turkey etc. GDIN has organized multiple technology matching and investor relations events to introduce Korean companies and their innovative technologies to potential international partners.

At the year-end performance report event, held on December 19, GDIN recognized companies that successfully established joint ventures. Changsoft I&I, a digital construction management system company, was highlighted for its success in establishing joint ventures in Japan and Vietnam. CFO Jongeun Park of Changsoft I&I shared, “We were facing stagnating revenue growth, and expanding into new markets was critical. With GDIN’s support, we were able to establish joint ventures in Japan and Vietnam, allowing us to tailor our products to local market needs.”

Other companies that successfully established joint ventures in 2024 include Medicos Biotech, Bloomsbury Lab, Arbaim, Eucast, Pixelro, Hansol root one, Eco-Peace, and IESG.

GDIN CEO Jongkap Kim commented, “Unlike simple joint investments or distribution networks, these technology-driven joint ventures are based on market demand, ensuring their long-term sustainability. If these joint ventures achieve success in the local markets and even go public, they could offer multiple exit opportunities, creating a strong growth model for all involved.”

About GDIN 

Global Digital Innovation Network (formerly known as Born2Global Centre), registered under the Ministry of Science & ICT, is an independent foundation that promotes and fosters collaboration between next-level innovative companies from South Korea and the world.

Since 2013, we have established over 160 international partnerships, supported over 3,000 tech companies, conducted over 20,000 consulting services, and helped companies raise $3.6 billion USD in investments.

View original content to download multimedia:https://www.prnewswire.com/news-releases/gdin-successfully-supports-establishment-of-10-new-joint-ventures-in-2024-alone-302337060.html

SOURCE GDIN

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