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YDS Pharmatech’s New Generative Diffusion Model Significantly Improves Structure-Based PROTAC Optimization and Ternary Interaction Analysis; Presentation at Drug Discovery Chemistry 2023 Conference

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ALBANY, N.Y., April 7, 2023 /PRNewswire/ — A groundbreaking study by a team of scientists at YDS Pharmatech, Inc. has introduced an innovative Generative Diffusion Model (GDM) for sampling ensembles of degrader-induced ternary interactions, enabling a more effective approach to structure-based optimization of Proteolysis Targeting Chimeras (PROTACs). The new model provides an efficient method for modeling ternary complexes and enhances the understanding of ligand-induced protein-protein interactions.

YDS Pharmatech will present their findings at the upcoming Drug Discovery Chemistry 2023 conference, showcasing the potential of the GDM approach to significantly enhance PROTAC optimization and ternary interaction analysis.

Traditionally, structure-based optimization of PROTACs has been a challenging task due to the difficulty of accurately modeling ternary structures. Conventional computational methods, such as RosettaDock, predict protein-protein complexes and then attempt to fit molecules into the interface. However, these methods are often limited in their ability to fully capture the dynamic nature of ternary interactions.

Xing Che, CEO of YDS Pharmatech, shared his thoughts on the breakthrough: “Our research team’s adoption of a generative diffusion model for sampling conformation ensembles and efficiently modeling ternary complexes has led to remarkable performance and new insights into the underlying mechanisms of PROTAC function. As one of the earliest adopters of using generative models for ternary thermodynamics interactions, I am amazed by the precision and insights from such modeling when our team presented the results.”

“YDS Pharmatech is a company with impressive expertise in simulation and AI technology. We have had the pleasure of collaborating with YDS on several ternary complex modeling projects, and the results have been consistently promising. We are confident that our fruitful association with them will continue to bring valuable insights and positively impact the progress of our research.” Commented by Kota Murasaki, Computational chemist of Mitsubishi Tanabe Pharma Corporation.

About YDS Pharmatech, Inc.:

YDS Pharmatech, Inc. is a drug discovery company developing computational platforms for multispecific drugs. The company uses AI-accelerated enhanced sampling molecular dynamics simulations to study ternary complex interactions, thermodynamics, and kinetics. Endeavoring to contribute to induced proximity studies and making degrader discovery transition from serendipitous to rational design. YDS Pharmatech focuses on PROTACs and molecular glue protein degraders at its current stage. Their interdisciplinary team of scientists collaborates with researchers worldwide to pioneer innovative treatments for various diseases.

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SOURCE YDS Pharmatech, Inc.

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MMA SMARTIES Thailand 2024 – Celebrates Unparalleled Marketing Innovation and Excellence in Thailand

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BANGKOK, Nov. 23, 2024 /PRNewswire/ — The SMARTIES Thailand 2024 Awards brought together pioneers and the brightest minds of the advertising and marketing world, celebrating marketing innovation. Ultimately, 47 exceptional winners were honored, comprising 13 Gold, 15 Silver, 8 Bronze awards and 11 industry awards.

More than just a celebration, the SMARTIES Awards are a global movement that empowers brands, advertisers, agencies, publishers, and technology enablers. With over 50,000 entries globally, SMARTIES has extensive reach, encompassing 19 country awards, 4 regional awards, and one global awards program. This year, Thailand presented numerous impressive entries spanning diverse sectors, underscoring the country’s influence in strategic marketing and creative innovation.

SMARTIES Thailand 2024 honored the best in the industry with a remarkable lineup of winners. Brilliant & Million, Thailand was awarded Digital Agency of the Year, while Grab took home both Publisher of the Year and Brand of the Year. Friends & Mana Company Limited was named Independent Agency of the Year, and Spa-Hakuhodo secured Creative Agency of the Year. M&C Saatchi emerged as the Media Agency of the Year, and Babi Mild was recognized as the Most Resilient Brand of the Year. Publicis Groupe earned the title of Holding Agency Company of the Year, while the Juror’s Choice Award went to the impactful “Under My Skin” campaign. Mondelēz International claimed the honor of Advertiser of the Year, and Best in Show was awarded to the captivating “Oreo Pokemon Catch ‘Em All!” campaign.

Check Out the Winner List Here! 

A rigorous selection process, led by a dedicated jury panel featuring top minds in marketing in Thailand, identified the best campaigns. These campaigns strengthened engagement through advanced technology, and elevated marketing practices.

“SMARTIES continues to set new benchmarks in the industry,” said Rohit Dadwal, CEO of MMA Global APAC & Global Head of SMARTIES™ Worldwide. “This year’s winners have demonstrated unparalleled brilliance, proving that Thailand is a hub for exceptional marketing talent. SMARTIES is not just about winning awards; it’s about pushing boundaries and setting global standards. With the launch of our new SMARTIES Sonic logo this year, we are redefining how the SMARTIES brand resonates and engages with audiences around the world, marking a new era of recognition and innovation”.

Winning a SMARTIES award brings more than recognition. Winners gain a competitive edge, credibility, and an impact on prestigious rankings, such as the MMA SMARTIES Business Impact Index, RECMA, and the WARC Media 100.

About MMA Global: MMA Global is the leading global trade association for marketers, providing essential resources and expertise to empower marketers to navigate the complex world of Marketing. With a commitment to driving innovation and effectiveness, MMA Global plays a pivotal role in shaping the future of marketing.

SMARTIES: SMARTIES is the prestigious marketing awards program hosted by MMA Global, recognizing excellence in Marketing. The SMARTIES Awards celebrate the most innovative and impactful campaigns that push the boundaries of creativity and drive measurable business impact in today’s dynamic landscape.

View original content to download multimedia:https://www.prnewswire.com/apac/news-releases/mma-smarties-thailand-2024—celebrates-unparalleled-marketing-innovation-and-excellence-in-thailand-302310807.html

SOURCE MMA Global APAC

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Redefining the Standard of Care: Introducing the Aulisa® Monitor Camera for Advanced Patient Monitoring

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PALO ALTO, Calif., Nov. 22, 2024 /PRNewswire/ — Aulisa® Medical USA, Inc., a leader in FDA-cleared, wearable, wireless continuous vital sign monitoring technology, proudly announces the launch of the Aulisa® Monitor Camera, an innovative solution designed to revolutionize patient care in both hospital and home settings. Seamlessly integrating with the Aulisa® Vital Signs Monitoring System, this advanced camera offers caregivers and healthcare professionals enhanced monitoring capabilities and peace of mind.

Redefining the Standard of Care
Hospitals constantly balance delivering exceptional patient care with managing operational costs. The Aulisa® Monitor Camera redefines patient monitoring by providing advanced, centralized solutions that enhance clinical and operational excellence. Designed to optimize patient care, the Aulisa® Monitor Camera integrates with the Centralized Multiple Patient Monitoring (CMPM) System, enabling simultaneous, wireless monitoring of oxygen saturation (SpO2), pulse rate, and body temperature across multiple patients from a centralized nursing station. With a simple app, the Aulisa® Monitor Camera can be integrated into a CMPM. In addition to monitoring a patient’s vital signs, caregivers and family members (such as parents of an infant) can also view the patient’s image and hear their voice. This feature is especially important in specific situations, such as for parents of an infant in the NICU.

This transformative approach eliminates cumbersome wires, streamlines operations, and ensures timely interventions, ultimately improving patient outcomes, enhancing safety standards, and optimizing workflow efficiency while driving significant cost savings and financial performance for healthcare facilities. With a steadfast commitment to compassionate, data-driven care and innovative solutions, Aulisa® Medical is advancing patient health and redefining healthcare excellence, one patient at a time.

Advanced Features for Comprehensive Care
The Aulisa® Monitor Camera offers crystal-clear 2K resolution with night vision, ensuring high-quality visuals day and night. Its two-way audio and human tracking features enable real-time communication and automated movement monitoring, while effortless Wi-Fi integration allows for quick and simple setup via mobile or web devices. With dual functionality as a standalone home surveillance camera, the Aulisa® Monitor Camera delivers unmatched flexibility for various care scenarios.

Engineered for Hospital Excellence
Designed with hospitals and patients in mind, the Aulisa® Monitor Camera addresses the unique demands of modern healthcare settings. From NICUs to patient rooms, it offers caregivers the ability to remotely monitor patients with visual, audio, and motion tracking capabilities. This streamlines workflows, enhances safety, and allows providers to focus on delivering compassionate care while staying equipped with FDA-cleared technology.

Founder’s Vision
“Introducing the Aulisa® Monitor Camera is a natural extension of our mission to enhance patient care and empower healthcare professionals,” said Augustine (Augie) Lien, founder and CEO of Aulisa Medical USA, Inc. “We strive to provide innovative solutions that bring peace of mind to caregivers and families alike. By delivering FDA-cleared technology with seamless functionality, we’re making it easier to ensure safety, connectivity, and exceptional care in every setting.”

Why Choose Aulisa®?
The Aulisa® Monitor Camera enhances efficiency by enabling remote monitoring, reducing physical check-ins, and providing reliable, FDA-cleared technology trusted by healthcare professionals worldwide. It is now available for purchase by healthcare facilities, caregivers, and families.

To learn more about the Aulisa Monitor Camera, the Guardian Angel® CMPM System and other Aulisa Medical products, visit:

www.aulisa.com/products/aulisa-monitor-camerawww.aulisa.com/products/cmpmwww.aulisa.com/collections/guardian-angel-remote-gateway-systems

About Aulisa Medical
Based in Silicon Valley, Aulisa® Medical is a leading medical technology company founded by serial medical technologies entrepreneur, Augustine (Augie) Lien. The company specializes in developing wireless, wearable monitoring systems that provide continuous, cloud-based vital sign data in both clinical and home environments. Through the development of new healthcare innovations, Aulisa® continues to grow the application of digital health technologies that empower both consumers and healthcare providers, incorporating Artificial Intelligence (AI) technologies that can detect adverse events and potentially save lives.

Media Contact:
Kyle Thompson, Vice President of Sales & Marketing
Email: kyle.thompson@aulisa.com
Direct: (650) 387-0001
www.aulisa.com

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SOURCE Aulisa Medical USA, Inc.

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Redefining Financial Frontiers: Nucleus Software Celebrates 30 Years with Synapse 2024 in Singapore

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SINGAPORE, Nov. 23, 2024 /PRNewswire/ — The thriving IndiaSingapore partnership in banking and technology reached a new milestone as Nucleus Software celebrated 30 years of transformative innovation at Synapse 2024, held in Singapore. The event underscored the company’s role in redefining financial services across Southeast Asia (SEA) and the globe, bringing together leaders in finance and technology to explore a shared vision for the future of banking.

Synapse 2024 celebrated 30 years of Nucleus Software’s leadership in driving transformative change across Singapore and Southeast Asia’s financial ecosystem. The event also shone a spotlight on the Global Finance & Technology Network (GFTN), an initiative supported by the Monetary Authority of Singapore (MAS) to champion responsible technology adoption. The event highlighted the deepening synergies between India and Singapore, driven by their shared commitment to innovation, cross-border collaboration, and financial inclusion. As the financial services sector undergoes rapid evolution with advancements in artificial intelligence, blockchain, and digital banking, these partnerships are setting the stage for a more connected, resilient, and inclusive global ecosystem.

Vishnu R. Dusad, Co-founder and Managing Director of Nucleus Software, reflected on the milestone: “For over 30 years, we’ve had the privilege of aligning our journey with Singapore’s ascent as a global financial powerhouse. Back in 1994, when we chose to go East instead of West, it was a bold and emotional decision—guided by our belief in Singapore as a hub for innovation and collaboration. We saw then what remains true today: Singapore is at the heart of the global financial landscape, a place where new ideas take root, and partnerships thrive.”

The event brought together a distinguished array of participants, highlighting the transformative potential of IndiaSingapore collaboration. Mr. Piyush Gupta, CEO of DBS Group and the Guest of Honor, set the tone for the event with his opening remarks, emphasizing the transformative role of big tech in reimagining scalable, customer-centric financial services in the digital age.

Following his address, key speakers enriched the discussions with their insights. Mr. Sopnendu Mohanty, Chief Fintech Officer at the Monetary Authority of Singapore and Group CEO-Designate of The Global Finance & Technology Network (GFTN), underlined the importance of fostering responsible technology adoption and building inclusive financial ecosystems. Mr. Vinod Rai, globally respected public policy expert, Distinguished Visiting Research Fellow at the National University of Singapore, and former Comptroller and Auditor General of India, shared his perspectives on governance and policy frameworks in financial systems. Mr. S.M. Acharya, Chairman of Nucleus Software and former Defence Secretary of India, offered a visionary outlook on leveraging technology to modernize and secure banking frameworks. Finally, Mr. Pieter Franken, Co-founder and Director of GFTN (Japan), a global FinTech pioneer and deep tech innovator, discussed the future of decentralized finance and its implications for the financial sector.

The event showcased the transformative role of technology in global financial systems, emphasizing innovations that set benchmarks for scalability and inclusivity. Panelists discussed the importance of localized solutions, the challenges of cross-border integration, and leveraging dual business models to optimize capital and foster public participation. The dialogue highlighted the need for common standards, unified frameworks like APIs, and collaborative efforts to accelerate financial inclusion and drive global connectivity in the digital age.

For 30 years, Nucleus Software has consistently introduced advanced lending and banking solutions that support financial institutions’ evolving needs in Singapore and South East Asia. Driven by lean development methodologies like Acceptance Test-Driven Development (ATDD) and Continuous Integration/Continuous Delivery (CICD), Nucleus Software continues to push boundaries in efficient, flexible, and secure financial technology.

Photo: https://mma.prnewswire.com/media/2565374/Synapse_2024.jpg
Logo: https://mma.prnewswire.com/media/2565373/Nucleus_Software_Logo.jpg

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